Endocrinology ExpEctEd ValuEs & S.I.

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Endocrinology
Expected
Values
& S.I.
Unit
Conversion
Tables
Disclaimer:
This data applies to
the highly sensitive and
specific assay methods
developed, validated,
and performed solely
at Endocrine Sciences.
Endocrinology Expected Values and
S.I. Unit Conversion Tables
TABLE OF CONTENTS
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 – 3
Expected Values . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 – 67
S.I. Unit Conversion Table . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 – 79
(E) = Esoterix Test Number
(L) = LabCorp Test Number
Esoterix is a wholly owned subsidiary of LabCorp where its Endocrine Sciences laboratory
operates as a Center of Excellence for specialized endocrinology. Endocrine Sciences’ testing
can be accessed directly from Esoterix or through LabCorp and any of its regional facilities.
1
EXPECTED VALUES
ENDOCRINOLOGY
INTRODUCTION
As a specialized laboratory, Endocrine Sciences recognizes the need for comprehensive
reference values for hormone tests. In response to this need, we maintain an active program
to determine hormone levels in healthy individuals at all ages and over a broad range of
physiologic conditions. The value of this information is appreciated by physicians, who because
of the nature of endocrine disease, rely extensively on laboratory results for diagnosis.
Diagnostic problems in pediatric endocrinology are further complicated by dramatic changes
in hormone levels which occur during the neonatal and prepubertal periods, at adrenarche,
and during pubertal development. Comprehensive reference values are indispensable to the
assessment of hormonal dysfunction in children. Since its founding in 1972, Endocrine Sciences
has maintained a continuous program to obtain reference intervals in children.
Through collaborative studies conducted with pediatricians, hospitals and university research
centers, we have obtained comprehensive pediatric values for the majority of our tests. The
information accumulated over the past several years is published herein to facilitate the
interpretation of endocrine test results on pediatric patients. Endocrine Sciences would like
to express its gratitude to the many clinicians and researchers who have participated in our
program and generously contributed their time and patient samples.
2
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
The difficult nature of certain studies has limited the ability to collect all of the necessary
data through this program, therefore some values included here are from research publications.
This outside data is included only after extensive review and careful examination to insure
that methods demonstrated adequate specificity and that values were comparable to those
determined at Endocrine Sciences. Determining reference values for hormone tests is
an on-going program. We will continue to collect data on current assays and establish
reference values for new tests. We cordially invite interested physicians to join us in this
continuing project.
(E) Esoterix Test Number
(L) LabCorp Test Number
3
EXPECTED VALUES
ENDOCRINOLOGY
Acid Labile Subunit (ALS)
BLOOD ASSAYS
500012 (E)
500120 (L)
Range (mg/L)
INFANTS
0 – 2 Months: 0.2 – 5.1
3 – 6 Months: 0.7 – 5.6 7 – 11 Months: 0.7 – 7.9
4
Mean
2.1
3.4
4.0
PREPUBERTAL
1 – 2 Years: 3 – 4 Years: 5 – 7 Years: 8 – 10 Years: 0.9 – 9.3
1.9 – 10
2.3 – 11
4.2 – 13
5.5
6.8
7.2
8.9
PUBERTAL
11 – 13 Years: 14 – 18 Years: 5.6 – 16
5.6 – 16
12
12
ADULTS
19 – 25 Years: 26 – 35 Years: 36 – 45 Years: 46 – 55 Years: 56 – 65 Years: 7.0 – 16
7.0 – 16
7.0 – 16
7.0 – 16
7.0 – 16
12
12
11
11
10
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Adrenocorticotropic Hormone (ACTH)
BLOOD ASSAYS
500011 (E)
500471 (L)
ADULTS
Range
6 – 48 pg/mL
Aldosterone
BLOOD ASSAYS
500014 (E)
500467 (L)
Ad Lib Sodium Intake
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
SupineUpright
(ng/dL)
(ng/dL)
5 – 635
19 – 141
not applicable
not applicable
FULL-TERM INFANTS
3 Days:
7 Days:
1 – 11 Months:
7 – 184
5 – 175
5 – 90
not applicable
not applicable
not applicable
CHILDREN
12 – 23 Months:
24 Months – 9 Years:
10 – 14 Years:
7 – 54
3 – 35
2 – 22
not applicable
5 – 80
4 – 48
ADULTS
3 – 16
7 – 30
Values are based on early morning samples from subjects on ad lib sodium intake.
Diurnal variations and values in pediatric patients on different sodium diets are
currently unavailable.
(E) Esoterix Test Number
(L) LabCorp Test Number
5
EXPECTED VALUES
ENDOCRINOLOGY
Aldosterone, Urine (Includes Creatinine)
urine ASSAYS
500018 (E)
Ad Lib Sodium Intake
NEWBORN
1 – 3 Days:
500760 (L)
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
0.5 – 5
20 – 140
PREPUBERTAL CHILDREN
4 – 10 Years:
1 – 8
4 – 22
ADULTS
Low Sodium Intake:
Normal Sodium:
High Sodium:
20 – 80
3 – 19
2 – 12
Not determined
1.5 – 20
Not determined
Aldosterone excretion rates in infants and children on high and low sodium intake are not
available. Aldosterone excretion rates in newborns correlate highly with potassium: sodium
ratios but not with sodium intake.
6
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Alpha Subunit
BLOOD ASSAYS
500016 (E)
140269 (L)
RANGE (ng/mL)
ADULT
Males:
< 50 Years:
0.05 – 0.53
>/= 50 Years:
0.09 – 0.76
Females:
Premenopausal:
Postmenopausal:
0.04 – 0.38
0.09 – 1.23
Androstanediol Glucuronide
500026 (E)
BLOOD ASSAYS
500881 (L)
RANGE (ng/dL)
PREPUBERTAL CHILDREN
0 – 10 Years:
< 5 – 42
ADULTS
Males:
Females*:
190 – 900
35 – 200
*Occasionally, normal females with no evidence of hirsutism may have levels well beyond the
normal range.
(E) Esoterix Test Number
(L) LabCorp Test Number
7
EXPECTED VALUES
ENDOCRINOLOGY
Androstenedione, HPLC-MS/MS
BLOOD ASSAYS
500030 (E)
500152 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
63 – 935
31 – 35 Weeks, Day 4:
50 – 449
FULL–TERM INFANTS
1 – 7 Days:
<10 – 279
Levels decrease rapidly to a range of <52 ng/dL after one week.
1 – 11 Months:
<10 – 37
Androstenedione gradually decreases during the first six months to prepubertal levels.
PREPUBERTAL CHILDREN
1 – 10 Years:
<10 – 17
PUBERTY
TANNER AGE STAGE (years)
RANGE
(ng/dL)
MEAN (ng/dL)
MALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
<10 – 17
<10 – 33
17 – 72
15 – 115
33 – 192
<10
12
36
52
77
TANNER
STAGE
FEMALE
1
2
3
4
5
AGE (years)
RANGE
(ng/dL)
MEAN
(ng/dL)
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
<10 – 17
<10 – 72
50 – 170
47 – 208
50 – 224
<10
33
97
105
137
RANGE (ng/dL)RANGE (ng/dL)
ADULTS
MALE
FEMALE (entire cycle)
18 – 40 Years:
44 – 186
28 – 230
Postmenopausal:
<10 – 93
8
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Antidiuretic Hormone (ADH) *RUO*
500035 (E)
BLOOD ASSAYS
500846 (L)
RANGE (pg/mL)
ADULTS
0.7 – 3.8
With normal serum osmolality
Anti-Mullerian Hormone (AMH), Serum *RUO*
500043 (E)
BLOOD ASSAYS
500183 (L)
RANGE (ng/mL)
Males
0 – 13 Days:
15.5 – 48.7
14 Days -11 Months:
39.1 – 91.1
12 Months – 6 Years:
48.0 – 83.2
7 – 8 Years:
33.8 – 60.2
Adult:
3.0 – 5.4
Females
0 – 8 Years:
Adult:
(E) Esoterix Test Number
0.0 – 7.1
0.0 – 6.9
(L) LabCorp Test Number
9
EXPECTED VALUES
ENDOCRINOLOGY
Bone Specific Alkaline Phosphatase, Serum
500074 (E)
BLOOD ASSAYS
500602 (L)
RANGE (ng/mL)
Males
<20.2
Females
Premenopausal:
Postmenopausal:
<=14.3
<=22.4
Calcitonin
BLOOD ASSAYS
500047 (E)
500636 (L)
RANGE (pg/mL)
MALES
0 – 150y:
< 8.4
FEMALES
0 – 150y:
10
< 5.0
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Catecholamines, Fractionated, Plasma
BLOOD ASSAYS
500052 (E)
500883 (L)
NOREPINEPHRINE EPINEPHRINE
RANGE (pg/mL)RANGE (pg/mL)
NEWBORN
1 – 7 Days:
200 – 420
20 – 130
CHILDREN
1 – 16 Years:
Basal:
150 – 400
20 – 115
ADULTS
20 – 54 Years:
Basal:
Standing: 125 – 310
167 – 515
20 – 97
20 – 109
55 – 64 Years:
Basal:
Standing: 130 – 455
210 – 915
20 – 97
20 – 109
65 – 74 Years:
Basal:
Standing: 165 – 700
300 – 1140
20 – 97
20 – 109
Values were obtained from samples collected under optimal, basal conditions whenever
possible. Catecholamine levels are elevated by many variables, including the stress of
venipuncture and by numerous pharmacological agents.
(E) Esoterix Test Number
(L) LabCorp Test Number
11
EXPECTED VALUES
ENDOCRINOLOGY
Catecholamines, Fractionated, Urine, HPLC-MS/MS
(Includes Creatinine)
500062 (E)
URINE ASSAYS
500520 (L)
Note: Listed reference range values effective as of May 17th, 2010.
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
NOREPINEPHRINE
0 – 9 Years:
< 60
< 151
10 – 19 Years:
< 91
< 68
> 20 Years:
< 136
< 112
< 12
< 38
EPINEPHRINE
0 – 9 Years:
12
10 – 19 Years:
< 19
< 18
> 20 Years:
< 21
< 20
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Catecholamines, Total, Urine, HPLC-MS/MS
(Includes Creatinine)
500060 (E)
URINE ASSAYS
500473 (L)
Note: Listed reference range values effective as of May 17th, 2010.
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
0 – 9 Years:
< 66
< 204
10 – 19 Years:
< 108
< 85
> 20 Years:
< 144
< 113
(E) Esoterix Test Number
(L) LabCorp Test Number
13
EXPECTED VALUES
ENDOCRINOLOGY
Corticosteroid Binding Globulin (CBG)
500076 (E)
BLOOD ASSAYS
500130 (L)
RANGE (mg/dL)
NEWBORN
0 – 3 Weeks:
1.6 – 2.5
14
INFANTS
4 Weeks – 11 Months:
2.2 – 8.3
FEMALES
12 Months – 8 Years 4.3 – 10
MALES
12 Months – 9 Years 4.3 – 10
OLDER CHILDREN
AND ADULTS
2.3 – 3.9
ESTROGEN THERAPY
AND PREGNANCY
> 6.0
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Corticosterone, HPLC-MS/MS
BLOOD ASSAYS
500084 (E)
500135 (L)
RANGE (ng/dL)RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4: 235 – 1108
31 – 35 Weeks, Day 4: 150 – 1700
NEWBORN
1 – 7 Days: 30 Days – 11 Months: 70 – 850
80 – 1500
CHILDREN
1 – 16 Years: 8:00 a.m.
135 – 1860
4:00 p.m.
70 – 620
Adults
130 – 820
60 – 220
Cortisol, Free, Urine (Incl. Creatinine), HPLC-MS/MS
500102 (E)
URINE ASSAYS
500410 (L)
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
PREPUBERTAL CHILDREN 3 – 9
7 – 25
ADULT MALE
11 – 84
7 – 45
ADULT FEMALE
10 – 34
9 – 32
PREGNANCY
16 – 60
14 – 59
(E) Esoterix Test Number
(L) LabCorp Test Number
15
EXPECTED VALUES
ENDOCRINOLOGY
Cortisol, Saliva, HPLC-MS/MS
SALIVA ASSAYS
500094 (E)
500179 (L)
RANGE (ug/dL)
CHILDREN and adults
8:00 a.m. 0.025 – 0.600
Noon <0.010 – 0.330
4:00 p.m. 0.010 – 0.200
Midnight <0.010 – 0.090
Cortisol, Serum, HPLC-MS/MS
BLOOD ASSAYS
500092 (E)
500154 (L)
RANGE (ug/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
1 – 11
31 – 35 Weeks, Day 4:
2.5 – 9.1
16
FULL–TERM INFANTS
Day 3:
Day 7: 31 Days – 11 Months: 1.7 – 14
2.0 – 11
2.8 – 23
CHILDREN
12 Month – 15 Years:
8:00 a.m.
3.0 – 21
4:00 p.m.
Not Determined
ADULTS
8.0 – 19
4.0 – 11
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
C-Peptide, Plasma
BLOOD ASSAYS
500104 (E)
500642 (L)
RANGE (ng/mL)
CHILDREN
8:00 a.m. Fasting:
0.4 – 2.2
ADULTS
8:00 a.m. Fasting:
2 Hours Post Prandial
(Sustacal):
2 Hours Post Glucose:
0.4 – 2.1
1.2 – 3.4
2.0 – 4.5
C-Telopeptide, Serum (pg/mL)
500130 (E)
BLOOD ASSAYS
500089 (L)
RANGE
(pg/mL)
MALES
115 – 748
Females
Premenopausal
Postmenopausal
(E) Esoterix Test Number
112 – 738
142 – 1351
(L) LabCorp Test Number
17
EXPECTED VALUES
ENDOCRINOLOGY
Dehydroepiandrosterone (DHEA)
BLOOD ASSAYS
500116 (E)
500156 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
236 – 3640
31 – 35 Weeks, Day 4:
80 – 3150
FULL–TERM INFANTS
3 Days:
8 – 30 Days:
31 Days – 5 Months:
6 – 11 Months:
65 – 1250
50 – 760
26 – 385
20 – 100
PREPUBERTAL CHILDREN
12 Months – 5 Years:
6 – 7 Years:
8 – 10 Years:
20 – 130
20 – 275Values begin to increase progressively at
about six years of age prior to any physical
evidence of puberty.
31 – 345
PUBERTY
TANNER AGE RANGE
MEAN STAGE (years)
(ng/dL)
(ng/dL)
MALE 1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
ADULTS
20 – 50 Years:
18
31 – 345
110 – 495
170 – 585
160 – 640
250 – 900
156
300
390
395
505
TANNER AGE RANGE
STAGE (years)
(ng/dL)
FEMALE
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
31 – 345
150 – 570
200 – 600
200 – 780
215 – 850
MEAN
(ng/dL)
156
330
385
430
540
160 – 800
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Dehydroepiandrosterone Sulfate (DHEA-S)
BLOOD ASSAYS
500120 (E)
500161 (L)
RANGE (ug/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
123 – 882
31 – 35 Weeks, Day 4:
122 – 710
FULL–TERM INFANTS
3 Days:
88 – 356
1 – 11 Months:
5 – 111 ug/dL by first month,
5 – 48 ug/dL by 6 months.
PREPUBERTAL 1 – 5 Years:
< 5 – 57
CHILDREN
6 – 7 Years:
9 – 72
8 – 10 Years:
13 – 115
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
STAGE (years)
(ug/dL)
(ug/dL) STAGE
(years)
(ug/dL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
ADULTS
21 – 30 Years:
31 – 40 Years:
41 – 50 Years:
51 – 60 Years:
61 – 70 Years:
71 – 80 Years:
(E) Esoterix Test Number
13 – 83
42 – 109
48 – 200
102 – 385
120 – 370
36
93
122
206
230
1
2
3
4
5
MALE Range (ug/dL)
100 – 460
88 – 305
70 – 218
29 – 220
26 – 213
20 – 172
(L) LabCorp Test Number
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
19 – 144
34 – 129
32 – 226
58 – 260
44 – 248
MEAN
(ug/dL)
40
72
88
120
148
FEMALE Range (ug/dL)
76 – 255
48 – 247
19 – 210
20 – 157
10 – 115
not determined
19
EXPECTED VALUES
ENDOCRINOLOGY
Deoxycorticosterone (DOC), HPLC-MS/MS
500124 (E)
BLOOD ASSAYS
500138 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
20 – 105
34 – 36 Weeks, Day 4:
28 – 78
NEWBORN
Levels are markedly elevated at birth and
decrease rapidly during the first week to
the range of 7-49 as found in older infants.
20
FULL–TERM INFANTS
1 – 11 Months:
7 – 49
PREPUBERTAL CHILDREN
2 – 10 Years:
2 – 34
PUBERTAL CHILDREN
AND ADULTS
8:00 a.m.:
2 – 19
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Deoxypyridinolines, Urine (Includes Creatinine)
500127 (E)
URINE ASSAYS
500211 (L)
RANGE
ADULTS
Males: up to 5.4 nmole/mmole creatinine
Females:
Premenopausal:
Postmenopausal:
up to 7.4 nmole/mmole creatinine
up to 8.5 nmole/mmole creatinine
Results higher than the above ranges indicate an accelerated bone resorption rate.
Desoxycortisol, 11-, (Compound S for Metyrapone Test)
500136 (E)
BLOOD ASSAYS
500550 (L)
RANGE (ug/dL)
CHILDREN AND ADULTS
Baseline:
<1
Post Metyrapone:
Single Dose Test:
Multiple Dose Test:
(E) Esoterix Test Number
7 – 18
10 – 25
(L) LabCorp Test Number
21
EXPECTED VALUES
ENDOCRINOLOGY
Desoxycortisol, 11-, (Specific Compound S), HPLC-MS/MSBLOOD ASSAYS
500132 (E)
500171 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
110 – 1376
31 – 35 Weeks, Day 4:
48 – 579
FULL–TERM INFANTS
3 Days:
31 Days – 11 Months:
13 – 147
< 10 – 156
PREPUBERTAL CHILDREN
8:00 a.m.:
20 – 155
PUBERTAL CHILDREN
AND ADULTS
8:00 a.m.:
12 – 158
Dexamethasone, HPLC-MS/MS
500140 (E)
BLOOD ASSAYS
500118 (L)
RANGE (ng/dL)
ADULTS
Baseline:
< 30
8:00 a.m.: 140 – 295
Following 1 mg Dexamethasone, Previous Evening
8:00 a.m.: 1600 – 2850
Following 8 mg Dexamethasone, (4 x 2 mg Doses) Previous Day
22
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Dihydrotestosterone (DHT), HPLC-MS/MS
BLOOD ASSAYS
500144 (E)
500142 (L)
PREMATURE INFANTS
MALE RANGE (ng/dL)FEMALE RANGE (ng/dL)
10 – 53
2 – 13
FULL–TERM NEWBORNS
5 – 60
< 2 – 15
RANGE (ng/dL)
2 Weeks – 6 Months:
Male:DHT decreases rapidly the first week, then increases to
12–85 ng/dL between 30–60 days. Levels then decrease
gradually to prepubertal values by seven months.
Female:Levels decrease during the first month to < 3 ng/dL and
remain there until puberty.
PREPUBERTAL CHILDREN
<3
PUBERTY
TANNER AGE RANGE MEAN TANNER AGE RANGE
STAGE (years)
(ng/dL) (ng/dL) STAGE (years)
(ng/dL)
MALE
FEMALE
1
< 9.8
< 3
1
2
9.8 – 14.5 3 – 17 8
2
3
10.7 – 15.4 8 – 33 19
3
4
11.8 – 16.2 22 – 52 36
4
5
12.8 – 17.3 24 – 65 43
5
RANGE (ng/dL)
ADULTS
Male:
30 – 85
Female:
4 – 22
(E) Esoterix Test Number
(L) LabCorp Test Number
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
<3
5 – 12
7 – 19
4 – 13
3 – 18
MEAN
(ng/dL)
8
12
7
9
23
EXPECTED VALUES
ENDOCRINOLOGY
Dopamine, Urine, HPLC-MS/MS
URINE ASSAYS
500138 (E)
500733 (L)
Note: Listed reference range values effective as of May 17th, 2010.
RANGE (ug/24hrs)RANGE (ug/g creatinine)
0 – 9 Years:
< 415
< 1489
24
10 – 19 Years:
< 576
< 355
> 20 Years:
< 511
< 349
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Estradiol, HPLC-MS/MS
BLOOD ASSAYS
500152 (E)
500108 (L)
RANGE (pg/mL)
NEWBORNLevels are markedly elevated at birth and fall rapidly during the
first week to prepubertal values of < 15pg/mL.
1 – 6 Months:
Male:Levels increase to 10 – 32 pg/mL between 30 and 60 days,
then decline to prepubertal levels of < 15 pg/mL by six months.
1 – 11 Months:
Female:Levels increase to 5.0 – 50 pg/mL between 30 and 60 days, then
decline to prepubertal levels of < 15 pg/mL during the first year.
PREPUBERTAL CHILDREN
1 – 10 Years:
< 15 pg/mL
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
STAGE (years)
(pg/mL)
(pg/mL) STAGE (years)
(pg/mL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
5.0 – 11
5.0 – 16
5.0 – 25
10 – 36
10 – 36
8.0
11
16
22
21
ADULTS
Male:
8 – 35 pg/mL
Female:
Follicular:
Luteal:
Postmenopausal: 30 – 100 pg/mL
70 – 300 pg/mL
< 15 pg/mL
(E) Esoterix Test Number
(L) LabCorp Test Number
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
5.0 – 20
10 – 24
7.0 – 60
21 – 85
34 – 170
MEAN
(pg/mL)
8.0
16
25
47
110
25
EXPECTED VALUES
ENDOCRINOLOGY
Estrogens, Total
BLOOD ASSAYS
500148 (E)
500714 (L)
RANGE (pg/mL)
FULL–TERM INFANTS
Newborn:Markedly elevated at birth and fall rapidly during the first
week to < 25 by seven days.
30 Days – 11 Months:
Male:Levels increase to 10 – 40 between 30 – 60 days then
decline to < 25 by 12 months
Female:Levels increase to 10 – 60 between 30 – 60 days then
decline to < 25 by 12 months
PREPUBERTAL CHILDREN
1 – 10 Years:
< 25 pg/mL
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
STAGE (years)
(pg/mL)
(pg/mL) STAGE (years)
(pg/mL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
ADULTS
Male:
Female:
Follicular:
Luteal:
Postmenopausal:
10 – 38
17 – 45
22 – 55
27 – 80
25 – 80
20
30
41
53
50
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
10 – 46
22 – 63
24 – 110
40 – 180
60 – 280
MEAN
(pg/mL)
23
41
61
91
170
20 – 80 pg/mL
60 – 200 pg/mL
160 – 400 pg/mL
< 50 pg/mL
Note: Esoterix’ assay is specific for estrone and estradiol, and does not measure estriol.
26
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Estrone, HPLC-MS/MS
BLOOD ASSAYS
500172 (E)
500634 (L)
RANGE (pg/mL)
NEWBORNValues are strikingly elevated at birth, then
decrease rapidly during the first week to
prepubertal levels of < 15.
PREPUBERTAL CHILDREN
1 – 10 Years:
< 15 pg/mL
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
STAGE (years)
(pg/mL)
(pg/mL) STAGE (years)
(pg/mL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
5.0 – 17
10 – 25
15 – 25
15 – 45
20 – 45
11
16
21
33
32
1
2
3
4
5
ADULTS
Male:
10 – 50 pg/mL
Female:
Follicular:
Luteal:
30 – 100 pg/mL
90 – 160 pg/mL
Postmenopausal: < 40 pg/mL
(E) Esoterix Test Number
(L) LabCorp Test Number
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
4.0 – 29
10 – 33
15 – 43
16 – 77
29 – 105
MEAN
(pg/mL)
13
21
30
36
61
27
EXPECTED VALUES
ENDOCRINOLOGY
Follicle Stimulating Hormone (FSH) ECL
BLOOD ASSAYS
500192 (E) (Expressed in terms of W.H.O. International Standard, Human Pituitary FSH 83/575)
RANGE (mIU/mL)
502280 (L)
INFANTS
4 Weeks – 11 Months:
Male:
0.16 – 4.1
Levels are for infants from 4 weeks of age to one year. FSH in
males declines to prepubertal levels by the end of the first year.
Female:
0.24 – 14.2
Levels are for infants from 4 weeks of age to one year. FSH
declines more slowly than in males to reach prepubertal levels
by the end of the second year.
PREPUBERTAL CHILDREN
MALE
FEMALE
12 Months – 8 Years:
0.26 – 3.0
1.0 – 4.2
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE MEAN
STAGE (years)
(mIU/mL) (mIU/mL) STAGE (years)
(mIU/mL) (mIU/mL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
ADULT
Males 20 – 50 Years:
Females
Follicular & Luteal:
Mid–cycle:
Post Menopausal:
28
0.26 – 3.0
1.8 – 3.2
1.2 – 5.8
2.0 – 9.2
2.6 – 11.0
0.98
2.5
2.9
4.4
6.1
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
1.0 – 4.2
1.0 – 10.8
1.5 – 12.8
1.5 – 11.7
1.0 – 9.2
2.1
4.0
5.1
6.4
4.9
2.0 – 9.2
1.8 – 11.2
6 – 35
30 – 120
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Glutamic Acid Decarboxylase (GAD-65) Autoantibodies
500236 (E)
BLOOD ASSAYS
500611 (L)
RANGE
ALL AGES
< 0.5 U/mL
GlycoMark
BLOOD ASSAYS
500609 (E)
RANGES
500115 (L)
REFERENCE INTERVAL
(ug/mL) 1, 5AG
MALES
10.7 – 32.0
FEMALES
6.8 – 29.3
Growth Hormone Antibodies
500214 (E)
MEAN (SD)
(ug/mL) 1, 5AG
22.5 (5.8) 17.7 (6.2)
BLOOD ASSAYS
500144 (L)
RANGE
ALL AGES
Negative
(E) Esoterix Test Number
(L) LabCorp Test Number
29
EXPECTED VALUES
ENDOCRINOLOGY
Growth Hormone Binding Protein (GHBP)
500209 (E)
BLOOD ASSAYS
500177 (L)
RANGE (pmol/L)
CHILDREN
Under 2 Years:
<125 – 762
2 – 9 Years:
267 – 1638
10 – 14 Years:
431 – 1892
ADULTS
20 – 50 Years:
686 – 2019
LARON DWARFISM
< 125
Growth Hormone, ICMA
500213 (E)
BLOOD ASSAYS
500647 (L)
RANGE
All Ages
0 – 6 ng/mL
NOTE: GH is secreted episodically. An individual may have levels ranging from undetectable to
elevated over the course of a day.
RESPONSE TESTING (CHILDREN AND ADULTS):
GH response to provocative stimuli among normal individuals is highly variable. Response
values greater than 6 ng/mL using two-site assays have historically been considered to reflect
normal GH secretory function, while values below 6 ng/mL have been considered to indicate
some degree of GH deficiency. However, it should be noted that this limit is arbitrarily derived.
A significant percentage of normal controls exhibit response values well below this 6 ng/mL
limit. The clinical research literature should be consulted for a more recent detailed review of
the interpretation of GH response data.
30
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Growth Hormone, RIA
BLOOD ASSAYS
500212 (E)
500632 (L)
RANGE (ng/mL)
NEWBORN
1 Day:
5 – 53
2 – 7 Days:
5 – 27
31 Days – 11 Months:
2 – 10
Following an 8 – 12 hour overnight fast:
CHILDREN
0–6
ADULTS
0–6
RESPONSE TESTING (CHILDREN AND ADULTS):
The assessment of GH secretory capacity is complicated because of the episodic nature of GH
release from the pituitary. Basal GH levels can exhibit considerable variability throughout a
24-hour period, thus limiting their clinical utility. Alternatively, measurement of GH response
to various stimuli has commonly been used to improve the diagnostic assessment of GH
secretion. GH response to provocative stimuli among normal individuals, however, is highly
variable. Response values greater than 10 ng/mL have historically been considered to reflect
normal GH secretory function, while values below 10 ng/mL have been considered to indicate
some degree of GH deficiency. However, it should be noted that this limit is arbitrarily derived.
A significant percentage of normal controls exhibit response values well below this 10 ng/mL
limit. The clinical research literature should be consulted for a more recent detailed review of
the interpretation of GH response data.
(E) Esoterix Test Number
(L) LabCorp Test Number
31
EXPECTED VALUES
ENDOCRINOLOGY
Growth Hormone, Urine (Includes Creatinine)
500211 (E)
URINE ASSAYS
500330 (L)
RANGERANGE
Overnight Collection
(ng/g creatinine)
24 Hour
Collection
(ng/g creatinine)
PREPUBERTAL CHILDREN
1 – 8 Years
7.5 – 42
10.2 – 30.1
PUBERTAL CHILDREN
9 – 18 Years
6.7 – 39
9.3 – 29
ADULTS
19 – 43 Years
0.2 – 14.8
0.2 – 13
Hemoglobin A1c BLOOD ASSAYS
502080 (E)
501270 (L)
RANGE
ADULTS
4.2% – 5.9%
32
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Hydroxycorticosteroids, 17, Urine (Includes Creatinine)
500216 (E)
URINE ASSAYS
500852 (L)
Glenn–Nelson Procedure
RANGERANGE
(mg/24 hours)
(mg/g creatinine)
PREPUBERTAL CHILDREN
1 – 4 Years:
0.2 – 2.5
1.7 – 6.4
5 – 9 Years:
0.5 – 2.5
2.2 – 6.0
PUBERTAL CHILDREN
AND ADULTS
Male:
Female:
(E) Esoterix Test Number
3 – 10
2 – 6
(L) LabCorp Test Number
2.4 – 4.3
1.6 – 3.6
33
EXPECTED VALUES
ENDOCRINOLOGY
Hydroxycorticosterone, 18, HPLC-MS/MS
BLOOD ASSAYS
500088 (E)
500778 (L)
18–OH–Corticosterone/
18–OH–Corticosterone Aldosterone Ratio
RANGE (ng/dL)RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
10 – 670
1.0 – 4.5
31 – 35 Weeks, Day 4:
57 – 410
1.1 – 5.2
FULL–TERM INFANTS
3 Days:
31 Days – 11 Months:
31 – 546
5 – 220
2.6 – 5.3
2.3 – 6.0
CHILDREN
12 – 23 Months: 24 Months – 9 Years:
10 – 14 Years:
18 – 155
6 – 85
10 – 72
1.7 – 5.0
2.4 – 10.5
2.0 – 8.3
ADULTS
8:00 a.m. Supine:
8:00 a.m. Upright:
9 – 58
4 – 21
5 – 46
1.7 – 8.8
Samples were collected without regard to posture from subjects on ad lib sodium
intake. For additional information on the effects of posture and sodium intake, contact
the laboratory.
34
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Hydroxyindoleacetic Acid, 5- (5-HIAA), Urine
(Includes Creatinine)
500215 (E)
URINE ASSAYS
500720 (L)
RANGE(mg/24 hour)
ADULTS
< 16.0
Hydroxypregnenolone, 17-, HPLC-MS/MS
500262 (E)
BLOOD ASSAYS
140715 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
375 – 3559
31 – 35 Weeks, Day 4:
64 – 2380
FULL–TERM INFANTS
3 Days:
1 – 5 Months:
6 – 11 Months:
10 – 829
36 – 763
42 – 540
PREPUBERTAL CHILDREN
12 – 23 Months:
24 Months – 5 Years:
6 – 9 Years:
14 – 207
10 – 103
10 – 186
PUBERTAL AGE GROUPS
44 – 235
ADULTS
53 – 357
(E) Esoterix Test Number
(L) LabCorp Test Number
35
EXPECTED VALUES
ENDOCRINOLOGY
Hydroxyprogesterone, 17a-, (17-OHP), HPLC-MS/MS
BLOOD ASSAYS
500270 (E)
500163 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
124 – 841
31 – 35 Weeks, Day 4:
26 – 568
FULL–TERM INFANTS
Day 3:
7 – 77
Male 1 – 11 Months: Levels increase after the first week to peak values ranging
from 40 – 200 ng/dL between 30 and 60 days. Values then
decline to prepubertal range of 3 – 90 before one year.
Female 1 – 11 Months :
13 – 106
PREPUBERTAL CHILDREN
1 – 10 Years: 3 – 90
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
STAGE (years)
(ng/dL)
(ng/dL) STAGE (years)
(ng/dL)
MALE
FEMALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
ADULTS
3 – 90
5 – 115
10 – 138
29 – 180
24 – 175
1
2
3
4
5
MALE RANGE (ng/dL)
27 – 199
36
38
51
57
80
97
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
3 – 82
11 – 98
11 – 155
18 – 230
20 – 265 MEAN
(ng/dL)
31
49
70
91
108
FEMALE RANGE (ng/dL)
Follicular: 15 – 70
Luteal:
35 – 290
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
ICA-512 Autoantibodies 500255 (E)
BLOOD ASSAYS
141531 (L)
RANGE
All Ages
< 1.0 U/mL
IGF Binding Protein-1 (IGFBP-1)
500283 (E)
BLOOD ASSAYS
140822 (L)
RANGE (ng/mL)
PREPUBERTAL CHILDREN
Fasting:
30 – 1000
Random:
10 – 500
PUBERTAL CHILDREN
Fasting:
Random:
20 – 200
20 – 100
ADULTS
Fasting:
Random:
10 – 150
0 – 40
(E) Esoterix Test Number
(L) LabCorp Test Number
37
EXPECTED VALUES
ENDOCRINOLOGY
IGF Binding Protein-2 (IGFBP-2)
BLOOD ASSAYS
500284 (E)
500133 (L)
RANGE (ng/mL)
0 – 11 Months:
348 – 922
12 – 23 Months:
280 – 750
24 Months – 5 Years:
275 – 700
6 – 9 Years:
255 – 540
10 – 14 Years:
200 – 470
15 – 24 Years:
215 – 518
25 – 44 Years:
220 – 570
45 – 64 Years:
225 – 710
65 – 74 Years:
225 – 850
75 – 85 Years:
300 – 1038
38
MEAN
567
460
435
370
305
325
345
390
450
560
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
IGF Binding Protein-3 (IGFBP-3)
BLOOD ASSAYS
500281 (E)
500644 (L)
PREMATURE INFANTS
0 Days – 1 Month:
2 – 3 Months:
4 – 5 Months:
6 –11 Months:
RANGE (mg/L)
MEAN (mg/L)
0.3 – 1.4
0.9 – 2.3
0.4 – 2.2
1.0 – 2.3
0.9
1.6
1.5
1.5
FULL-TERM INFANTS
0 Days – 1 Month:
2 – 3 Months:
4 – 5 Months:
6 –11 Months:
0.4 – 1.7
0.5 – 2.1
0.6 – 2.4
0.5 – 2.4
0.9
1.3
1.4
1.4
CHILDREN
12 Months – 4 Years:
5 – 6 Years:
7 – 8 Years:
9 – 11 Years:
12 – 13 Years:
14 – 15 Years:
16 – 18 Years:
0.8 – 3.0
1.5 – 3.4
2.1 – 4.2
2.0 – 4.8
2.1 – 6.2 2.2 – 5.9
2.5 – 4.8
2.1
2.4
3.0
3.3
3.8
4.2
3.8
ADULTS
19 – 30 Years:
31 – 70 Years:
2.0 – 4.2
1.9 – 3.6
3.0
2.7
(E) Esoterix Test Number
(L) LabCorp Test Number
39
EXPECTED VALUES
ENDOCRINOLOGY
IGF-I
BLOOD ASSAYS
500282 (E)
500485 (L)
TERM RANGE (ng/mL) MEAN
NEWBORNS AND INFANTS
Birth:
15 – 109
59
1 Day – 2 Months:
15 – 109
55
3 – 4 Months:
7 – 124
50
5 – 6 Months:
7 – 93
41
7 – 11 Months:
15 – 101
56
PRE–TERM* RANGE (ng/mL) MEAN
21 – 93
23 – 163
23 – 171
15 – 132
15 – 179
51
81
74
61
77
* Values from preterm infants were determined at these ages from expected term gestation
40
CHILDREN AND YOUNG ADULTS
1 – 2 Years:
3 – 4 Years:
5 – 6 Years:
7 – 8 Years:
9 – 10 Years:
11 – 12 Years:
13 – 14 Years:
15 – 16 Years:
17 – 18 Years:
19 – 20 Years:
MALE
MEAN FEMALE
MEAN
30 – 122
54 – 178
60 – 228 113 – 261
123 – 275
139 – 395
152 – 540 257 – 601
236 – 524
281 – 510
76
116
144
187
199
267
346
429
380
371
56 – 144
74 – 202
82 – 262
112 – 276
140 – 308
132 – 376
192 – 640
217 – 589
176 – 452
217 – 475
100
138
172
194
224
254
416
403
314
323
ADULTS
21 – 30 Years:
31 – 40 Years: 41 – 50 Years: 51 – 60 Years: 61 – 70 Years: 71 – 80 Years: 155 – 432
132 – 333
121 – 237
68 – 245
60 – 220
36 – 215
289
226
160
153
132
131
87 – 368
106 – 368
118 – 298
53 – 287
75 – 263
54 – 205
237
225
205
172
180
156
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
IGF-II
BLOOD ASSAYS
500228 (E)
141770 (L)
RANGE (ng/mL)
PREPUBERTAL
334 – 642
MEAN
488
PUBERTAL
245 – 737
491
ADULTS
288 – 736
512
Insulin
BLOOD ASSAYS
500220 (E)
500564 (L)
PREPUBERTAL
0 – 8 Years:
RANGE (uU/mL)*
0 – 13
PUBERTAL CHILDREN
AND ADULTS
0 – 17
ADULTS
2 Hours Post Meal
(Sustacal):
7.6 – 26
2 Hours Post
Glucose (75 gm):
15 – 53
* Following a 4 – 12 hour fast
(E) Esoterix Test Number
(L) LabCorp Test Number
41
EXPECTED VALUES
ENDOCRINOLOGY
Insulin Antibodies
BLOOD ASSAYS
500225 (E)
CHILDREN
4 – 19 Years:
42
141598 (L)
BINDING CAPACITY (uU/mL)
< 5.0
ADULTS
20 – 40 Years:
< 5.0
TYPE I DIABETES
5 – 420
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Insulin, Free and Total
BLOOD ASSAYS
500226 (E)
501561 (L)
RANGE (uU/mL)
NON–DIABETIC
In the absence of insulin–binding antibodies, the free and
total insulin assays are equivalent. However, this assay is
intended for use in diabetics with insulin autoantibody
present. Measurement is performed on acid–treated
samples and, therefore, the sensitivity and absolute values
by this method may differ from our direct insulin RIA.
Following a 4 – 12 hour fast:
INFANTS AND PREPUBERTAL
CHILDREN
0 – 13 uU/mL
PUBERTAL CHILDREN
AND ADULTS
0 – 17 uU/mL
INSULIN DEPENDENT
DIABETIC PATIENTS
Total insulin levels are dependent on the binding capacity of
circulating antibodies and the patient’s insulin dose. Values range from about 50 uU/mL to more than 1000 uU/mL. Free
insulin levels vary depending on the capacity and affinity of circulating insulin–binding antibodies and the dose of
insulin given to the patient. Values range from non–diabetic
levels up to about 100 uU/mL.
(E) Esoterix Test Number
(L) LabCorp Test Number
43
EXPECTED VALUES
ENDOCRINOLOGY
Ketosteroids, 17-, (17-KS), Urine (Includes Creatinine)
500230 (E)
URINE ASSAYS
501809 (L)
RANGERANGE
(mg/24 hours)
(mg/g creatinine)
CHILDREN
1 – 4 Years:
< 1.0 – 2.0
Not Determined
5 – 9 Years:
< 1.0 – 3.2
Not Determined
10 – 12 Years:
1.0 – 5.0
Not Determined
13 – 14 Years:
1.0 – 5.5
Not Determined
15 – 16 Years:
Male:
3.0 – 13
Not Determined
Female:
2.5 – 8.0
Not Determined
ADULTS
Male:
Female:
44
10 – 25
6 – 14
6 .7 – 12
5.6 – 10
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Leptin
BLOOD ASSAYS
500237 (E)
500716 (L)
RANGE (ng/mL)RANGE (ng/mL)
MALE FEMALE
ADULTS (BMI = 22)
0.7 – 5.3
3.3 – 18.3
Range is 5th – 95th percentile.
NOTE: Leptin values are gender–dependent and highly correlated with the Body Mass Index
(BMI). This reference range is provided only for an average BMI value. Contact Esoterix to
obtain reference ranges correlated with other BMI’s. To obtain appropriate data, please furnish
patient’s age and sex, plus height and weight, or BMI.
(E) Esoterix Test Number
(L) LabCorp Test Number
45
EXPECTED VALUES
ENDOCRINOLOGY
Luteinizing Hormone (LH), ECL
BLOOD ASSAYS
500234 (E)
502286 (L)
RANGE (mIU/mL)
(Expressed In Terms of W.H.O. 2ND International Standard, Human Pituitary LH 80/552)
INFANTS
2 Weeks – 11 Months:Values begin to increase about two weeks after birth to a
range of 0.02 – 7.0 mIU/mL within the first three months,
then decline to prepubertal values, by the end of the first
year.
PREPUBERTAL CHILDREN
12 Months – 8 Years:
0.02 – 0.3
PUBERTY
TANNER AGE RANGE
MEAN TANNER AGE RANGE
MEAN
STAGE (years)
(mIU/mL) (mIU/mL) STAGE (years)
(mIU/mL) (mIU/mL)
MALE
FEMALE
1
2
3
4 – 5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 17.3
ADULTS
Male:
Female:
Follicular:
Mid–cycle:
Luteal:
Postmenopausal: 46
0.02 – 0.3
0.2 – 4.9
0.2 – 5.0
0.4 – 7.0
0.09
1.8
1.9
2.6
1
2
3
4 – 5
< 9.2
0.02 – 0.18 0.06
9.2 – 13.7 0.02 – 4.7 0.72
10.0 – 14.4 0.10 – 12.0 2.3
10.7 – 18.6 0.4 – 11.7 3.3
1.5 – 9.0 mIU/mL
2.0 – 9.0 mIU/mL
18.0 – 49.0 mIU/mL
2.0 – 11.0 mIU/mL
20.0 – 70.0 mIU/mL
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Macroprolactin
500375 (E)
BLOOD ASSAYS
500324 (L)
RANGE
< 50%
NOTE: Normal populations are defined as having low percentage of macroprolactin (<50%).
(E) Esoterix Test Number
(L) LabCorp Test Number
47
EXPECTED VALUES
ENDOCRINOLOGY
Metanephrines, Fractionated Urine (Includes Creatinine) URINE ASSAYS
500240 (E)
501533 (L)
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
NORMETANEPHRINE
CHILDREN
< 1 Year:
Not Determined
180 – 1900
12 – 23 Months:
Not Determined
250 – 830
24 Months – 7 Years:
Not Determined
150 – 735
8 – 14 Years:
Not Determined
95 – 705
ADULTS
110 – 720
109 – 596
METANEPHRINE
CHILDREN
< 1 Year:
12 – 23 Months:
24 Months – 7 Years:
8 – 14 Years:
Not Determined
Not Determined
Not Determined
Not Determined
150 – 310
60 – 250
55 – 460
70 – 380
ADULTS
35 – 278
22 – 205
Pediatric values were determined on both random and overnight urine collections.
48
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Metanephrines, Total, Urine (Includes Creatinine)
500242 (E)
URINE ASSAYS
500480 (L)
RANGERANGE
(ug/24 hours)
(ug/g creatinine)
CHILDREN
< 1 Year:
Not Determined
410 – 2000
12 – 23 Months:
Not Determined
300 – 1200
24 Months – 7 Years:
Not Determined
200 – 900
8 – 14 Years:
Not Determined
140 – 830
ADULTS
300 – 900
180 – 700
Pediatric values were determined on both random and overnight collections.
Microalbumin, Urine (Includes Creatinine)
502440 (E)
URINE ASSAYS
500870 (L)
RANGERANGE
(mg/24 hours)
(mg/g creatinine)
ADULTS
Overnight Collection:
Not Determined
< 15
24 Hour Collection:
< 25
< 20
(E) Esoterix Test Number
(L) LabCorp Test Number
49
EXPECTED VALUES
ENDOCRINOLOGY
Parathyroid Hormone, Intact (IPTH) (Includes Calcium)
500246 (E)
BLOOD ASSAYS
500692 (L)
RANGE
Children and Adults
10 – 65 pg/mL
Pregnanetriol, Urine (Includes Creatinine)
500256 (E)
URINE ASSAYS
500340 (L)
RANGE RANGE
(mg/24 hour)
(mg/g creatinine)
INFANTS
50
<0.2
Not Determined
CHILDREN
<1.0
0.1 – 0.9
ADULTS
<2.0
0.1 – 1.6
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Pregnenolone, HPLC-MS/MS
500258 (E)
BLOOD ASSAYS
140707 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
260 – 2104
34 – 36 Weeks, Day 4:
203 – 1024
NEONATES
1 – 7 Days:
150 – 2000
Levels decrease after birth, and are within the prepubertal range, by three months.
PREPUBERTAL CHILDREN
20 – 140
PUBERTAL AND ADULTS
< 20 – 150
(E) Esoterix Test Number
(L) LabCorp Test Number
51
EXPECTED VALUES
ENDOCRINOLOGY
Progesterone, HPLC-MS/MS
500266 (E)
BLOOD ASSAYS
500167 (L)
MALES
1-16 Years
Adults
RANGE (ng/dL)
<10 – 15
<10 – 11
FEMALES
1 – 10 Years
11 Years
12 Years
13 Years
14 Years
15 Years
16 Years
RANGE (ng/dL)
<10 – 26
<10 – 255
<10 – 856
<10 – 693
<10 – 1204
<10 – 1076
<10 – 1294
ADULT
CYCLE DAYS
1 – 6
7 – 12
13 – 15
16 – 28
RANGE (ng/dL)
<10 – 17
<10 – 135
<10 – 1563
<10 – 2555
POST MENOPAUSAL
<10 ng/dL
Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23.
52
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Proinsulin
BLOOD ASSAYS
500272 (E)
500722 (L)
PROINSULIN/INSULIN*
PROINSULIN
(Molar Ratio As %)
RANGE (pmol/L)RANGE
NORMAL CHILDREN
Fasting:
1.8 – 10
6.4 – 16
NORMAL ADULTS
Fasting:
1.7 – 12
3.4 – 21
* Ratio calculated using actual insulin value, not the sum of insulin and proinsulin in the
denominator.
Prolactin
BLOOD ASSAYS
500274 (E)
500557 (L)
RANGE (ng/mL)
NEWBORN
1 – 7 Days:
30 – 495
1 – 8 Weeks: Values decline during the first two months of life to those
observed in adult males 3-18 and females 3-24.
CHILDREN AND ADULTS
Male:
Female:
(E) Esoterix Test Number
3 – 18
3 – 24
(L) LabCorp Test Number
53
EXPECTED VALUES
ENDOCRINOLOGY
Renin, Plasma (Plasma Renin Activity)
500278 (E)
BLOOD ASSAYS
500458 (L)
RANGE (ng/dL/hr)
PREMATURE
1 – 7 Days:
1100 – 16, 700
FULLTERM
1 – 7 Days:
200 – 3500
Plasma renin activity in newborns is elevated and highly variable. Premature infants generally
exhibit substantially higher values ranging from 1100 – 16,700 ng/dL/hr.
CHILDREN*
31 Days – 11 Months:
12 Months – 2 Years:
3 – 4 Years:
5 – 9 Years:
10 – 14 Years:
235 – 3700
171 – 1115
100 – 650
50 – 585
50 – 330
SUPINEUPRIGHT
RANGE (ng/dL/hr)RANGE (ng/dL/hr)
ADULTS**
20 – 160
70 – 330
* Normal Sodium Diet, Supine Posture
** Normal Sodium Diet
NOTE: Normal studies of plasma renin activity in young children and adolescents
are incomplete.
54
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Sex Hormone Binding Globulin (SHBG), IRMA
500299 (E)
BLOOD ASSAYS
500848 (L)
RANGE (nmol/L)
INFANTS
1 Month – 2 Years:
60 – 252
PREPUBERTAL CHILDREN
1 – 8 Years:
72 – 220
PUBERTAL AGES
Males: Females: 16 – 100
36 – 125
ADULTS
Males: Females:
Premenopausal
Postmenopausal
(E) Esoterix Test Number
20 – 60
40 – 120
28 – 112
(L) LabCorp Test Number
55
EXPECTED VALUES
ENDOCRINOLOGY
Testosterone, Bioavailable BLOOD ASSAYS
500288 (E)
500650 (L)
RANGE(ng/dL)
INFANTS AND PREPUBERTAL
CHILDREN
1 – 9 Years:
< 0.2 – 1.3 ng/dL
PUBERTY
TANNER AGE RANGE
MEAN STAGE (years)
(ng/dL)
(ng/dL)
MALE
1
2
3
4 – 5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 17.3
< 0.2 – 3.4
2 – 58
12
12 – 70 30
84 – 350 210
TANNER AGE RANGE
STAGE (years)
(ng/dL)
FEMALE
1
2
3
4 – 5
ADULTS
Male:
20 – 39 Yrs:
40 – 49 yrs
50 – 69 yrs
70 – 79 yrs
RANGE (ng/dL)
Female:
1.1 – 14.3
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 18.6
MEAN
(ng/dL)
< 0.2 – 3.4
0.8 – 4.7 3.6
1.1 – 9.6 4.7
2.3 – 13.9 6.1
128 – 430
95 – 350
95 – 285
60 – 240
NOTE: For additional information on interpretation of Bioavailable Testosterone levels, contact
the laboratory.
56
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Testosterone, Free, by Equilibrium Dialysis
BLOOD ASSAYS
500290 (E)
500102 (L)
FULL–TERM INFANTS
1 – 15 Days:
1 – 2 Months:
3 – 4 Months:
5 – 6 Months:
PREPUBERTAL CHILDREN
1 – 10 Years:
MALE RANGE (pg/mL)
FEMALE RANGE (pg/mL)
1.5 – 31
3.3 – 18
0.7 – 14 0.4 – 4.8
0.5 – 2.5
0.1 – 1.3
0.3 – 1.1
0.2 – 0.6
0.15 – 0.6
0.15 – 0.6
PUBERTYComprehensive values for free testosterone by dialysis for
both males and females throughout puberty are currently
unavailable.
ADULTS
% FREE TESTOSTERONE
FULL–TERM INFANTS
1 – 15 Days:
1 – 2 Months:
3 – 4 Months:
5 – 6 Months:
PREPUBERTAL CHILDREN
1 – 10 Years:
52 – 280
1.1 – 6.3
MALE RANGE (%)
FEMALE RANGE (%)
0.9 – 1.7
0.4 – 0.8
0.4 – 1.1
0.4 – 1.0
0.8 – 1.5
0.4 – 1.1
0.5 – 1.0
0.5 – 0.8
0.4 – 0.9
0.4 – 0.9
PUBERTYComprehensive values for free testosterone by dialysis for
both males and females throughout puberty are currently
unavailable.
ADULTS
(E) Esoterix Test Number
1.5 – 3.2
(L) LabCorp Test Number
0.8 – 1.4
57
EXPECTED VALUES
ENDOCRINOLOGY
Testosterone, Total, HPLC-MS/MS
BLOOD ASSAYS
500286 (E)
500159 (L)
MALE RANGE (ng/dL) FEMALE RANGE (ng/dL)
PREMATURE INFANTS
26 – 28 Weeks, Day 4:
59 – 125
5 – 16
31 – 35 Weeks, Day 4:
37 – 198
5 – 22
RANGE (ng/dL)
FULL–TERM INFANTS
Newborns:
75 – 400 20 – 64
Male 1 – 7 Months:
Levels decrease rapidly the first week to 20 – 50 ng/dL, then increase to 60 – 400 ng/dL
(Mean = 190) between 20 – 60 days. Levels then decline to prepubertal range of < 3 – 10 by
seven months.
Female 1 – 7 Months:
Levels decrease during the first month to <10 ng/dL and remain there until puberty.
PREPUBERTAL CHILDREN
1 – 10 Years: < 3 – 10
PUBERTY
TANNER AGE RANGE
MEAN STAGE (years)
(ng/dL)
(ng/dL)
MALE
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
< 3 – 10
18 – 150
100 – 320
200 – 620
350 – 970
4.9
42
190
372
546
TANNER AGE RANGE
STAGE (years)
(ng/dL)
FEMALE
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
< 3 – 10
7 – 28
15 – 35
13 – 32
20 – 38
MEAN
(ng/dL)
4.9
18
25
22
28
ADULTS 20 – 50 YearsRANGE (ng/dL)
Male:
350 – 1030
Female:
Premenopausal: 10 – 55
Postmenopausal: 7 – 40
58
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Thyroglobulin (w/Anti-thyroglobulin Screen), Comprehensive
500316 (E)
BLOOD ASSAYS
500540 (L)
RANGE (ng/mL)
THYROGLOBULIN ICMA
PREPUBERTAL CHILDREN 2.9 – 56
PUBERTAL CHILDREN
AND ADULTS
MEAN (ng/mL)
17
1.3 – 37
8.5
THYROGLOBULIN RIA
1 – 11 Months
12 –113
42
PREPUBERTAL CHILDREN
5 – 72
29
PUBERTAL CHILDREN
AND ADULTS
< 40
16
Assay quantitation limit: <0.1
Assay quantitation limit: <2.0
Thyroglobulin Antibodies (Anti-Tg)
500038 (E)
BLOOD ASSAYS
500555 (L)
RANGE (IU/mL)
Negative
<1.0
Positive
>or = 1.0
Low positive Thyroglobulin antibodies are seen in a portion of the asymptomatic populations
(E) Esoterix Test Number
(L) LabCorp Test Number
59
EXPECTED VALUES
ENDOCRINOLOGY
Thyroid Peroxidase Antibodies (Anti-TPO)
500042 (E)
BLOOD ASSAYS
500638 (L)
RANGE (IU/mL)
ALL AGES
0 – 20
Thyroid Stimulating Hormone (TSH), ICMA
500305 (E)
BLOOD ASSAYS
500477 (L)
RANGE (uU/mL)
PREMATURE INFANTS
26 – 32 Weeks,
Day 3 – 4:
0.8 – 6.9
FULL TERM INFANTS
Day 4:
1.3 – 16
Newborns: TSH surges within the first 15 – 60 minutes of life reaching
peak levels between 25 – 160 at about 30 minutes. Values
then decline rapidly and after one week are within the adult
normal range.
60
1 – 11 Months:
0.9 – 7.7
PREPUBERTAL CHILDREN
0.6 – 5.5
PUBERTAL CHILDREN
AND ADULTS
0.5 – 4.8
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Thyroxine (T-4)
BLOOD ASSAYS
500310 (E)
500348 (L)
RANGE (ug/dL)
PREMATURE INFANTS
26 – 30 Weeks,
Day 3 – 4:
2.6 – 14.0
FULL–TERM INFANTS
1 – 3 Days:
1 Week:
1 – 11 Months:
8.2 – 19.9
6.0 – 15.9
6.1 – 14.9
PREPUBERTAL CHILDREN
12 Months – 2 Years:
3 – 9 Years:
6.8 – 13.5
5.5 – 12.8
PUBERTAL CHILDREN
11 – 17 Years:
4.9 – 13.0
ADULTS
4.2 – 13.0
Thyroxine Binding Globulin (TBG)
500318 (E)
BLOOD ASSAYS
500724 (L)
RANGE (ug/mL)
CHILDREN
12.7 – 27.9
ADULTS
13.0 – 39.0
(E) Esoterix Test Number
(L) LabCorp Test Number
61
EXPECTED VALUES
ENDOCRINOLOGY
Thyroxine, Free by Dialysis and MS
500329 (E)
BLOOD ASSAYS
501902 (L)
RANGE (ng/dL)
1 – 11 years 0.65 – 1.9
PUBERTAL CHILDREN
AND ADULTS
0.8 – 1.7
PREGNANT FEMALES
1st Trimester (0-13.3 wks)
0.65 – 1.4
2nd Trimester (13.4-26.6 wks)
0.5 – 1.3
3rd Trimester (>26.6 wks)
0.5 – 1.1
Thyroxine, Free Automated
504001 (E)
BLOOD ASSAYS
500835 (L)
RANGE (ng/dL)
ADULTS (≥ 18yrs)
0.89 – 1.76
62
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Triiodothyronine (T-3)
BLOOD ASSAYS
500322 (E)
500563 (L)
RANGE (ng/dL)
PREMATURE INFANTS
26 – 30 Weeks,
Day 3 – 4:
24 – 132
FULL–TERM INFANTS
1 – 3 Days:
1 Week:
1 – 11 Months:
89 – 405
91 – 300
85 – 250
PREPUBERTAL CHILDREN
119 – 218
PUBERTAL CHILDREN
11 – 17 Years:
80 – 185
ADULTS
55 – 170
Triiodothyronine, Free Only
500323 (E)
BLOOD ASSAYS
500834 (L)
RANGE (pg/mL)
ADULTS
2.3 – 4.2
(E) Esoterix Test Number
(L) LabCorp Test Number
63
EXPECTED VALUES
ENDOCRINOLOGY
Triiodothyronine, Reverse *RUO*
500326 (E)
BLOOD ASSAYS
500875 (L)
RANGE (ng/dL)
NEWBORNS
90 – 250
Reverse T–3 levels are elevated at birth and during the first few days of life. Values then
decrease rapidly and are within the adult range by one week.
CHILDREN AND ADULTS
10 – 50
TSH Receptor Antibody (TRAb)
500308 (E)
BLOOD ASSAYS
500538 (L)
RANGE (U/L)
ALL AGES
Antibody Titer
64
<1 U/L = Negative
1.1 - 1.5 U/L = Equivocal
>1.5 U/L = Positive
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
EXPECTED VALUES
Vanillylmandelic Acid (VMA), Urine (Includes Creatinine) URINE ASSAYS
500330 (E)
500496 (L)
RANGERANGE
(mg/24 hours)
(mg/g creatinine)
CHILDREN
Birth – 11 Months:
Not Determined
3 – 17
12 – 23 Months:
Not Determined
4 – 12
24 Months – 14 Years:
Not Determined
2 – 11
ADULTS
0.7 – 6.8
1.5 – 7.0
Pediatric values were determined on both random and 8 hour urine collections.
Vitamin D, 1, 25-Dihydroxy, HPLC-MS/MS
500342 (E)
BLOOD ASSAYS
500600 (L)
RANGE (pg/mL)
NEWBORNS
0 – 30 Days <10 – 72
INFANTS AND CHILDREN
31 Days – 17 Years 15 – 90
ADULTS
> 18 Years
21 – 65
(E) Esoterix Test Number
(L) LabCorp Test Number
65
EXPECTED VALUES
ENDOCRINOLOGY
Vitamin D, 25-Hydroxy, HPLC-MS/MS
500338 (E)
BLOOD ASSAYS
500510 (L)
RANGE (ng/mL)
NEWBORNS
5 – 42
CHILDREN AND ADULTS
10 – 55
Note: Adult target levels are 32-100 ng/mL
Vitamin D, 25-Hydroxy Fractionated, HPLC-MS/MS
500337 (E)
BLOOD ASSAYS
500116 (L)
Reference range provided is the same as Total Vitamin D above
66
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
(E) Esoterix Test Number
EXPECTED VALUES
(L) LabCorp Test Number
67
S.I. UNIT CONVERSION TABLE
68
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
ACTH (Corticotropin) Antidiuretic Hormone (ADH) Albumin Aldosterone, Serum Aldosterone, Urine Aldosterone/Creatinine Androstanediol Androstanediol Glucuronide Androstenedione Androsterone, Urine Androsterone/Creatinine Angiotensin I Angiotensin II Angiotensin III Angiotensin I Converting Enzyme Atrial Natriuretic Peptide (ANP) C-Peptide C-Peptide, Urine C-Peptide/Creatinine Calcitonin Calcium Calcium, Urine 4.5000 1.0840 0.1000 0.0360 0.3604 3.1859 0.0292 0.0469 0.0286 0.2905 2.5680 1.2960 1.0460 0.9310 1.0000 3.0800 3.0210 3.0210 26.7109 3.4180 4.0080 40.0800 pmol/L pmol/L g/L pmol/L nmol/d nmol/mmol
pmol/L pmol/L pmol/L umol/d umol/mmol
pmol/L pmol/L pmol/L U/L pmol/L nmol/L nmol/L nmol/mmol
pmol/L mmol/L mmol/d pg/mL
pg/mL
g/dL
ng/dL
ug/24 h
ug/g
ng/dL
ng/dL
ng/dL
mg/24 h
mg/g
pg/mL
pg/mL
pg/mL
mU/mL
pg/mL
ng/mL
ng/mL
ug/g
pg/mL
mg/dL
mg/24 h
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Catecholamines, Urine Catecholamines/Creatinine Corticosterone 18-Hydroxycorticosterone Cortisol, Serum Cortisol, Urine Cortisol/Creatinine Cortisone Creatinine, Urine Cyclic Amp, Urine Cyclic Amp/Creatinine Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone-Sulfate (DHEA-S)
Deoxycorticosterone (DOC) 18-Hydroxydeoxycorticosterone (18-OH-DOC)
11-Desoxycortisol (Compound S) Dexamethasone Dihydrotestosterone (DHT) Dopamine, Plasma Dopamine, Urine nmol/d nmol/mmol
pmol/L pmol/L nmol/L nmol/d nmol/mmol
pmol/L umol/d umol/L nmol/mmol
pmol/L nmol/L 0.1762 1.5572 0.0347 0.0362 0.0363 0.3625 3.2045 0.0361 0.1131 1.0000 0.0088 0.0288 0.0368 ug/24 h
ug/g
ng/dL
ng/dL
ug/dL
ug/24 h
ug/g
ng/dL
mg/24 h
nmol/mL
umol/g
ng/dL
ug/dL
pmol/L pmol/L 0.0331 0.0347 ng/dL
ng/dL
pmol/L pmol/L pmol/L pmol/L nmol/d 0.0346 0.0393 0.0290 0.1530 0.1530 ng/dL
ng/dL
ng/dL
pg/mL
ug/24 h
(E) Esoterix Test Number
(L) LabCorp Test Number
69
S.I. UNIT CONVERSION TABLE
70
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Dopamine/Creatinine Endorphin, Beta Epinephrine, Plasma Ephinephrine, Urine Epinephrine/Creatinine Estradiol Estriol Estrogens, Serum Estrone Estrone Sulfate Folic Acid Follicle Stimulating Hormone (FSH) Follicle Stimulating Hormone, Urine FSH/Creatinine Gastrin Glucagon Growth Hormone Human Chorionic Gonadotropin (HCG)
HCG, Urine HCG/Creatinine 5-Hydroxyindoleacetic Acid (5-HIAA), Urine
nmol/mmol pmol/L pmol/L nmol/d nmol/mmol pmol/L pmol/L pmol/L pmol/L pmol/L pmol/L IU/L IU/d IU/mmol ng/L ng/L ug/L IU/L 1.3528 4.0000 0.1831 0.1831 1.6186 0.272 0.0288 0.271 0.270 0.0350 0.0441 1.0000 1.0000 8.8420 1.0000 1.0000 1.0000 1.0000 ug/g
pg/mL
pg/mL
ug/24 h
ug/g
pg/mL
ng/dL
pg/mL
pg/mL
ng/dL
ng/dL
mIU/mL
IU/24 h
IU/g
pg/mL
pg/mL
ng/mL
mIU/mL
IU/d IU/mmol nmol/d 1.0000 8.8420 0.1912 IU/24 h
IU/g
ug/24 h
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
5-HIAA/Creatinine nmol/mmol Homovanillic Acid (HVA), Urine nmol/d HVA/Creatinine nmol/mmol 17-Hydroxycorticosteroids, Urine nmol/d 17-Hydroxycorticosteroids/Creatinine nmol/mmol IGF-I (Somatomedin C) nmol/L IGF-II nmol/L Inhibin U/L Insulin pmol/L 17-Ketosteroids, Urine umol/d 17-Ketosteroids/Creatinine umol/mmol Luteinizing Hormone (LH) IU/L Luteinizing Hormone, Urine IU/d LH/Creatinine IU/mmol Metanephrine, Urine nmol/d Metanephrine/Creatinine nmol/mmol Metanephrines,Total, Urine nmol/d Metanephrines,Total/Creatinine nmol/mmol Methoxytyramine, Urine nmol/d Methoxytyramine/Creatinine nmol/mmol Norepinephrine, Plasma pmol/L Norepinephrine, Urine nmol/d Norepinephrine/Creatinine nmol/mmol 1.6906 0.1822 1.6110 0.3625 3.2045 7.6490 7.5000 0.0010 0.1394 0.2884 2.5495 1.0000 1.0000 8.8420 0.1972 1.7432 0.1902 1.6814 0.1672 1.4786 0.1692 0.1692 1.4957 (E) Esoterix Test Number
(L) LabCorp Test Number
ug/g
ug/24 h
ug/g
ug/24 h
ug/g
ng/mL
ng/mL
U/mL
uU/mL
mg/24 h
mg/g
mIU/mL
IU/24 h
IU/g
ug/24 h
ug/g
ug/24 h
ug/g
ug/24 h
ug/g
pg/mL
ug/24 h
ug/g
71
S.I. UNIT CONVERSION TABLE
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
Normetanephrine, Urine Normetanephrine/Creatinine Osteocalcin Parathyroid Hormone Prednisolone Prednisone Pregnanediol, Urine Pregnanediol/Creatinine Pregnanetriol, Urine Pregnanetriol/Creatinine Pregnenolone 17-Hydroxypregnenolone Progesterone 17-Hydroxyprogesterone 20-Hydroxyprogesterone Prolactin Renin (Plasma Renin Activity) Reverse T-3 Secretin Sex Hormone Binding Globulin (SHBG)
72
MULTIPLY TO
BY
FIND
nmol/d 0.1832 nmol/mmol 1.6195 nmol/L 6.5000 pmol/L 9.5000 pmol/L 0.0361 pmol/L 0.0358 umol/d 0.3205 ng/dLumol 2.8332 umol/d 0.3365 umol/mmol 2.9747 pmol/L 0.0317 pmol/L 0.0333 pmol/L 0.0315 pmol/L 0.0331 pmol/L 0.0317 ug/L 1.0000 ng/L/s 3.6000 pmol/L 0.0651 pmol/L 3.0550 nmol/L 0.0288 ug/24 h
ug/g
ng/mL
pg/mL
ng/dL
pmol/L
mg/24 h
mg/g/mmol
mg/24 h
mg/g
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
ng/mL
ng/mL/h
ng/dL
pg/mL
ug/dL
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
(Binding Capacity)
Somatostatin-14 Somatostatin-28 Testosterone Free Testosterone Testosterone, Urine Testosterone/Creatinine Thyroglobulin Thyroid Stimulating Hormone (TSH)
Thyroxine (T-4) Thyroxine Binding Globulin Thyrotropin Releasing Hormone (TRH)
Triiodothryonine (T-3) Vanillylmandelic Acid (VMA), Urine VMA/Creatinine Vitamin B-12 25-Hydroxy-Vitamin D 1, 25-Dihydroxy-Vitamin D (E) Esoterix Test Number
(L) LabCorp Test Number
MULTIPLY TO
BY
FIND
pmol/L pmol/L pmol/L pmol/L nmol/d nmol/mmol ug/L mU/L 1.6380 3.2760 0.0288 0.2884 0.2884 2.5495 1.0000 1.0000 pg/mL
pg/mL
ng/dL
pg/mL
ug/24 h
ug/g
ng/mL
uU/mL
nmol/L
mg/L pmol/L 0.0777 0.1000 0.3620 ug/dL
mg/dL
pg/mL
pmol/L nmol/d nmol/mmol pmol/L nmol/L pmol/L 0.0651 0.1982 1.7525 0.1355 0.4006 0.4166 ng/dL
ug/24 h
ug/g
ng/dL
ng/mL
pg/mL
73
S.I. UNIT CONVERSION TABLE
74
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
ACTH (Corticotropin) Antidiuretic Hormone (ADH) Albumin Aldosterone, Serum Aldosterone, Urine Aldosterone/Creatinine Androstanediol Androstanediol Glucuronide Androstenedione Androsterone, Urine Androsterone/Creatinine Angiotensin I Angiotensin II Angiotensin III Angiotensin I Converting Enzyme Atrial Natriuretic Peptide (ANP) C-Peptide C-Peptide, Urine C-Peptide/Creatinine Calcitonin Calcium Calcium, Urine 0.2222 0.9225 10.0000 27.7469 2.7747 0.3139 34.1997 21.3447 34.9162 3.4423 0.3894
0.7716 0.9560 1.0741 1.0000 0.3247 0.3310 0.3310 0.0374 0.2926 0.2495 0.0250 pg/mL pg/mL g/dL ng/dL ug/24 h ug/g ng/dL ng/dL ng/dL mg/24 h mg/g pg/mL pg/mL pg/mL mU/mL pg/mL ng/mL ng/mL ug/g pg/mL mg/dL mg/24 h pmol/L
pmol/L
g/L
pmol/L
nmol/d
nmol/mmol
pmol/L
pmol/L
pmol/L
umol/d
umol/mmol
pmol/L
pmol/L
pmol/L
U/L
pmol/L
nmol/L
nmol/L
nmol/mmol
pmol/L
mmol/L
mmol/d
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Catecholamines, Urine Catecholamines/Creatinine Corticosterone 18-Hydroxycorticosterone Cortisol, Serum Cortisol, Urine Cortisol/Creatinine Cortisone Creatinine, Urine Cyclic Amp, Urine Cyclic Amp/Creatinine Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone-Sulfate (DHEA-S)
Deoxycorticosterone (DOC) 18-Hydroxydeoxycorticosterone (18-OH-DOC)
11-Desoxycortisol (Compound S) Dexamethasone Dihydrotestosterone (DHT) Dopamine, Plasma Dopamine, Urine Dopamine/Creatinine ug/24 h ug/g ng/dL ng/dL ug/dL ug/24 h ug/g ng/dL mg/24 h nmol/mL umol/g ng/dL ug/dL 5.6770 0.6422 28.8600 27.5938 27.5862 2.7586 0.3121 27.7393 8.8420 1.0000 113.1000 34.6741 27.2109 nmol/d
nmol/mmol
pmol/L
pmol/L
nmol/L
nmol/d
nmol/mmol
pmol/L
umol/d
umol/L
nmol/mmol
pmol/L
nmol/L
ng/dL ng/dL 30.2572 28.8600 pmol/L
pmol/L
ng/dL ng/dL ng/dL pg/mL ug/24 h ug/g 28.8684 25.4777 34.4353 6.5359 6.5359 0.7392 pmol/L
pmol/L
pmol/L
pmol/L
nmol/d
nmol/mmol
(E) Esoterix Test Number
(L) LabCorp Test Number
75
S.I. UNIT CONVERSION TABLE
76
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Endorphin, Beta Epinephrine, Plasma Ephinephrine, Urine Epinephrine/Creatinine Estradiol Estriol Estrogens, Serum Estrone Estrone Sulfate Folic Acid Follicle Stimulating Hormone (FSH) Follicle Stimulating Hormone, Urine FSH/Creatinine Gastrin Glucagon Growth Hormone Human Chorionic Gonadotropin (HCG)
HCG, Urine HCG/Creatinine 5-Hydroxyindoleacetic Acid (5-HIAA), Urine
pg/mL pg/mL ug/24 h ug/g pg/mL ng/dL pg/mL pg/mL ng/dL ng/dL mIU/mL IU/24 h IU/g pg/mL pg/mL ng/mL mIU/mL 0.2500 5.4615 5.4615 0.6178 3.6711 34.6741 3.6845 3.6982 28.6123 22.6552 1.0000 1.0000 0.1131 1.0000 1.0000 1.0000 1.0000 I
pmol/L
pmol/L
nmol/d
nmol/mmol
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
IU/L
IU/d
IU/mmol
ng/L
ng/L
ug/L
U/L
IU/24 h IU/g ug/24 h 1.0000 0.1131 5.2301 IU/d
IU/mmol
nmol/d
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Homovanillic Acid (HVA), Urine ug/24 h HVA/Creatinine ug/g 17-Hydroxycorticosteroids, Urine ug/24 h 17-Hydroxycorticosteroids/Creatinine ug/g IGF-I (Somatomedin C) ng/mL IGF-II ng/mL IGF-II ng/mL Inhibin
U/mL Insulin uU/mL 17-Ketosteroids, Urine mg/24 h 17-Ketosteroids/Creatinine mg/g Luteinizing Hormone (LH) mIU/mL Luteinizing Hormone, Urine IU/24 h LH/Creatinine IU/g Metanephrine, Urine ug/24 h Metanephrine/Creatinine ug/g Metanephrines,Total, Urine ug/24 h Metanephrines,Total/Creatinine ug/g Methoxytyramine, Urine ug/24 h Methoxytyramine/Creatinine ug/g Norepinephrine, Plasma pg/mL Norepinephrine, Urine ug/24 h Norepinephrine/Creatinine ug/g 5.4885 0.6207 2.7586 0.3121 0.1307 0.1333 0.1333 1000.0 7.1750 3.4674 0.3922 1.0000 1.0000 0.1131 5.0710 0.5736 5.2576 0.5948 5.9809 0.6764 5.9100 5.9100 0.6686 (E) Esoterix Test Number
(L) LabCorp Test Number
nmol/d
nmol/mmol
nmol/d
nmol/mmol
nmol/L
nmol/L
nmol/L
U/L
pmol/L
umol/d
umol/mmol
IU/L
IU/d
IU/mmol
nmol/d
nmol/mmol
nmol/d
nmol/mmol
nmol/d
nmol/mmol
pmol/L
nmol/d
nmol/mmol
77
S.I. UNIT CONVERSION TABLE
78
ENDOCRINOLOGY
HORMONE
WHEN
YOU
KNOW
MULTIPLY TO
BY
FIND
Normetanephrine, Urine Normetanephrine/Creatinine Osteocalcin Parathyroid Hormone Prednisolone Prednisone Pregnanediol, Urine Pregnanediol/Creatinine Pregnanetriol, Urine Pregnanetriol/Creatinine Pregnenolone 17-Hydroxypregnenolone Progesterone 17-Hydroxyprogesterone 20-Hydroxyprogesterone Prolactin Renin (Plasma Renin Activity) Reverse T-3 Secretin Sex Hormone Binding Globulin (SHBG)
5.4585 0.6175 0.1538 0.1053 27.7393 27.9018 3.1201 0.3530 2.9718 0.3362 31.5956 30.0752 31.7965 30.2572 31.5956 1.0000 0.2778 15.3610 0.3273 34.6741 ug/24 h ug/g ng/mL pg/mL ng/dL ng/dL mg/24 h mg/g mg/24 h mg/g ng/dL ng/dL ng/dL ng/dL ng/dL ng/mL ng/mL/h ng/dL pg/mL ug/dL nmol/d
nmol/mmol
nmol/L
pmol/L
pmol/L
pmol/L
umol/d
umol/mmol
umol/d
umol/mmol
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
ug/L
ng/L/s
pmol/L
pmol/L
nmol/L
Expected values apply to assays performed at Endocrine Sciences only.
ENDOCRINOLOGY
S.I. UNIT CONVERSION TABLE
HORMONE
WHEN
YOU
KNOW
(Binding Capacity)
Somatostatin-14 Somatostatin-28 Testosterone
Free Testosterone Testosterone, Urine Testosterone/Creatinine Thyroglobulin Thyroid Stimulating Hormone (TSH) Thyroxine (T-4) Thyroxine Binding Globulin Thyrotropin Releasing Hormone (TRH)
Triiodothryonine (T-3) Vanillylmandelic Acid (VMA), Urine VMA/Creatinine Vitamin B-12 25-Hydroxy-Vitamin D 1, 25-Dihydroxy-Vitamin D (E) Esoterix Test Number
(L) LabCorp Test Number
MULTIPLY TO
BY
FIND
pg/mL pg/mL ng/dL pg/mL ug/24 h ug/g ng/mL uU/mL ug/dL mg/dL pg/mL 0.6105 0.3053 34.6741 3.4674 3.4674 0.3922 1.0000 1.0000 12.8717 10.0000 2.7624 pmol/L
pmol/L
pmol/L
pmol/L
nmol/d
nmol/mmol
ug/L
mU/L
nmol/L
mg/L
pmol/L
ng/dL ug/24 h ug/g ng/dL ng/mL pg/ml 15.3610 5.0454 0.5706 7.3779 2.4963 2.4004 pmol/L
nmol/d
nmol/mmol
pmol/L
nmol/L
pmol/L
79
Disclaimer:
This data applies to
the highly sensitive and
specific assay methods
developed, validated,
and performed solely at
Endocrine Sciences.
4301 Lost Hills Road, Calabasas Hills, CA 91301
Endocrine Sciences
© 2010 LCA All Rights Reserved. L5167-0410-5

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