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ISSN: 2071-2510
Vol. 9 No. 1
For further information contact:
World Health Organization
Regional Office for the Eastern Mediterranean
Health Publications, Production & Dissemination (HPD)
Library & Health Literature Services (LHL)
Abdul Razzak Al-Sanhouri Street,
P.O. Box 7608,
Nasr City, Cairo 11371, Egypt
http://www.emro.who.int/lin
e-mail: [email protected]
Tel: +20 2 22765047
Fax: +20 2 22765424
IMEMR Current Contents
June 2011
Vol. 10 No. 2
Providing Access to Health Knowledge
to Build a Healthy Future
Index Medicus for the WHO
Eastern Mediterranean Region
with Abstracts
IMEMR Current Contents
June 2011
Vol. 10 No. 2
© World Health Organization 2011
All rights reserved.
The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever
on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or
concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate borderlines for which there may not
yet be full agreement.
The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the
World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of
proprietary products are distinguished by initial capital letters.
All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication.
However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the
interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising
from its use.
Publications of the World Health Organization can be obtained from Health Publications, Production and Dissemination, World Health
Organization, Regional Office for the Eastern Mediterranean, P.O. Box 7608, Nasr City, Cairo 11371, Egypt (tel: +202 2670 2535,
fax: +202 2670 2492; email: [email protected]). Requests for permission to reproduce, in part or in whole, or to translate publications of
WHO Regional Office for the Eastern Mediterranean – whether for sale or for noncommercial distribution – should be addressed to
Regional Adviser, Global Arabic Programme, WHO Regional Office for the Eastern Mediterranean, at the above address: email:
[email protected]
Design, layout and printing by WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt
ISSN: 2071-2510
Table of Contents
IMEMR Current Contents ................................................................................................... vii
Subject Index ....................................................................................................................... ix
ABO Blood-Group System ............................................................................................ 1
Accidents, Aviation ....................................................................................................... 1
Accidents, Traffic .......................................................................................................... 1
Acrocallosal Syndrome ................................................................................................. 2
Adnexal Diseases ......................................................................................................... 2
Aircraft .......................................................................................................................... 2
Albinism, Oculocutaneous ............................................................................................ 2
Algae ............................................................................................................................ 3
Alkaloids ....................................................................................................................... 3
Amino Acids ................................................................................................................. 3
Anemia ......................................................................................................................... 4
Anemia, Iron-Deficiency ............................................................................................... 4
Angioplasty, Transluminal, Percutaneous Coronary ..................................................... 4
Anodontia ..................................................................................................................... 5
Anticholesteremic Agents ............................................................................................. 5
Antidepressive Agents .................................................................................................. 6
Antigens, CD95 ............................................................................................................ 6
Antihypertensive Agents ............................................................................................... 7
Antineoplastic Agents, Phytogenic ............................................................................... 7
Apiaceae ......................................................................................................................7
Apnea ........................................................................................................................... 8
Appendectomy ............................................................................................................. 8
Attention Deficit Disorder with Hyperactivity ................................................................. 8
Behcet Syndrome ......................................................................................................... 9
beta-lactams .................................................................................................................9
Beverages .................................................................................................................. 10
Blepharophimosis ....................................................................................................... 10
Body Composition ...................................................................................................... 10
Body Fluids ................................................................................................................. 11
Body Mass Index ........................................................................................................ 11
Bone Density .............................................................................................................. 11
Breast Neoplasms ...................................................................................................... 12
Bundle-Branch Block .................................................................................................. 12
Burns .......................................................................................................................... 13
Camels .......................................................................................................................13
Cantharidin ................................................................................................................. 14
Carcinoma, Basal Cell ................................................................................................ 14
Carcinoma, Ductal, Breast .......................................................................................... 15
Carcinoma, Small Cell ................................................................................................ 15
Carnitine .....................................................................................................................15
Catfishes ....................................................................................................................16
Celiac Disease ........................................................................................................... 16
Cell Differentiation ...................................................................................................... 17
Cell Physiological Phenomena ................................................................................... 17
Central Serous Chorioretinopathy .............................................................................. 17
Cholestasis ................................................................................................................. 18
i
Classical Lissencephalies and Subcortical ................................................................. 18
Communication .......................................................................................................... 19
Congenital Abnormalities ............................................................................................ 19
Contraception ............................................................................................................. 19
Coronary Angiography................................................................................................ 20
Coronary Artery Bypass ............................................................................................. 20
Coronary Artery Disease ............................................................................................ 20
Cyclooxygenase 2 Inhibitors ....................................................................................... 21
Delivery of Health Care .............................................................................................. 21
Dental Devices, Home Care ....................................................................................... 21
Dermatomycoses........................................................................................................ 22
Diabetes Mellitus ........................................................................................................ 22
Diabetes Mellitus, Type 2 ........................................................................................... 22
Diet ............................................................................................................................. 23
Disease Management................................................................................................. 23
Drug Prescriptions ...................................................................................................... 23
Dysmenorrhea ............................................................................................................ 25
Ear, Inner .................................................................................................................... 25
Echinococcosis, Hepatic............................................................................................. 26
Education, Medical ..................................................................................................... 26
Education, Medical, Undergraduate ........................................................................... 27
Entamoeha histolytica ................................................................................................ 27
Epilepsy ......................................................................................................................27
Erythrocyte Indices ..................................................................................................... 28
Esophageal Fistula ..................................................................................................... 28
Esophageal Neoplasms.............................................................................................. 28
Eye Foreign Bodies .................................................................................................... 29
Fatty Acid-Binding Proteins ........................................................................................ 29
Fatty Liver ...................................................................................................................30
Fissure in Ano ............................................................................................................ 31
Fluoroquinolones ........................................................................................................ 31
Food Microbiology ...................................................................................................... 31
Food-Drug Interactions ............................................................................................... 32
Foreign Bodies ........................................................................................................... 32
Foxes.......................................................................................................................... 32
Ganglioneuroma ......................................................................................................... 33
Gangrene ................................................................................................................... 33
Glaucoma ................................................................................................................... 33
Glucagonoma ............................................................................................................. 34
Graves Ophthalmopathy............................................................................................. 34
Growth ........................................................................................................................34
Guillain-Barre Syndrome ............................................................................................ 35
Head and Neck Neoplasms ........................................................................................ 35
Health Manpower ....................................................................................................... 35
Health Personnel ........................................................................................................ 36
Health Services Research .......................................................................................... 36
Hearing ....................................................................................................................... 36
Hearing Loss, Sensorineural ...................................................................................... 37
Heart Defects, Congenital .......................................................................................... 37
Hepatitis B Surface Antigens ...................................................................................... 37
Hepatitis B Vaccines................................................................................................... 38
Hepatitis C Antibodies ................................................................................................ 38
Hepatitis C, Chronic.................................................................................................... 39
Hernia, Ventral ........................................................................................................... 40
ii
Homocysteine ............................................................................................................. 40
Horner Syndrome ....................................................................................................... 40
Humeral Fractures ...................................................................................................... 41
Hydroxyurea ............................................................................................................... 41
Hyperparathyroidism .................................................................................................. 42
Hyperprolactinemia..................................................................................................... 42
Hypertension, Renovascular ...................................................................................... 42
Ibuprofen .................................................................................................................... 43
Infection Control ......................................................................................................... 44
Influenza A virus, H1N1 Subtype ................................................................................ 44
Injections ....................................................................................................................45
Interferon Alfa-2a ........................................................................................................ 45
Intervertebral Disk Displacement ................................................................................ 46
Intestinal Diseases ..................................................................................................... 46
Intubation, Intratracheal .............................................................................................. 47
Iron ............................................................................................................................. 47
Kidney Neoplasms...................................................................................................... 47
Laryngeal Neoplasms ................................................................................................. 48
Laryngoscopy ............................................................................................................. 48
Leishmaniasis, Visceral .............................................................................................. 48
Lenses, Intraocular ..................................................................................................... 48
Leukemia, Lymphoid .................................................................................................. 49
Leukoeytes ................................................................................................................. 49
Lipoma........................................................................................................................ 50
Liver Function Tests ................................................................................................... 50
Mastitis ....................................................................................................................... 50
Measles ......................................................................................................................51
Measles Vaccine ........................................................................................................ 51
Medical Records ......................................................................................................... 52
Medication Errors ....................................................................................................... 52
Medicine, Traditional .................................................................................................. 52
Melatonin .................................................................................................................... 53
Meningioma ................................................................................................................ 53
Meningitis, Bacterial ................................................................................................... 53
Menorrhagia ............................................................................................................... 54
Mental Retardation ..................................................................................................... 54
Metformin ................................................................................................................... 55
Methemoglobin ........................................................................................................... 55
Miosis ......................................................................................................................... 56
Misoprostol ................................................................................................................. 56
Motor Activity .............................................................................................................. 57
Multiple Sclerosis........................................................................................................ 57
Mupirocin ....................................................................................................................57
Mycobacterium bovis .................................................................................................. 58
Mycoplasma ............................................................................................................... 58
Myelodysplastic Syndromes ....................................................................................... 59
Myeloproliferative Disorders ....................................................................................... 59
Myxoma ...................................................................................................................... 59
Necrobiotic Disorders ................................................................................................. 60
Neoplasms ................................................................................................................. 60
Nutrition Assessment.................................................................................................. 61
Obesity .......................................................................................................................61
Olfactory Bulb ............................................................................................................. 62
Oral Health ................................................................................................................. 62
iii
Orbit............................................................................................................................ 63
Orthodontics, Interceptive........................................................................................... 63
Osteoma, Osteoid....................................................................................................... 63
Overweight ................................................................................................................. 64
Pain ............................................................................................................................ 64
Pancreatic Neoplasms................................................................................................ 64
Paternity ..................................................................................................................... 65
Patient Satisfaction ..................................................................................................... 65
Pericarditis, Constrictive ............................................................................................. 65
Perinatal Mortality ....................................................................................................... 66
Phacoemulsification.................................................................................................... 66
Pharmacogenetics ...................................................................................................... 66
Physician's Practice Patterns ..................................................................................... 66
Physician-Patient Relations ........................................................................................ 67
Plant Extracts ............................................................................................................. 67
Plant Gums ................................................................................................................. 68
Plants, Medicinal ........................................................................................................ 68
Polycystic Ovary Syndrome ........................................................................................ 69
Polyps......................................................................................................................... 70
Postoperative Hemorrhage ......................................................................................... 71
Postpartum Hemorrhage ............................................................................................ 71
PPAR gamma ............................................................................................................. 72
Pregnancy Outcome ................................................................................................... 72
Pregnant Women........................................................................................................ 72
Prenatal Care ............................................................................................................. 73
Publications ................................................................................................................ 73
Purkinje Cells ............................................................................................................. 74
Referral and Consultation ........................................................................................... 74
Retinal Vein Occlusion ............................................................................................... 74
Retinoblastoma .......................................................................................................... 75
Rh-Hr Blood-Group System ........................................................................................ 75
Rhinitis, Allergic, Persnnial ......................................................................................... 76
Rhinitis, Allergic, Seasonal ......................................................................................... 76
Schistosomiasis .......................................................................................................... 76
Schools, Medical ........................................................................................................ 77
Sepsis......................................................................................................................... 77
Skin Diseases, Vesiculobullous .................................................................................. 78
Smoking ..................................................................................................................... 78
Snake Venoms ........................................................................................................... 79
Somatoform Disorders................................................................................................ 79
Soybeans ................................................................................................................... 79
Stomach ..................................................................................................................... 79
Stress, Psychological ................................................................................................. 80
Strongyloidiasis .......................................................................................................... 81
Students, Medical ....................................................................................................... 81
Substance-Related Disorders ..................................................................................... 81
Surgery, Computer-Assisted ...................................................................................... 82
Survival Analysis ........................................................................................................ 82
Technetium Tc 99m Sestamibi ................................................................................... 82
Theileria ...................................................................................................................... 83
Thyroid Function Tests ............................................................................................... 83
Thyroid Neoplasms..................................................................................................... 83
Thyrotoxicosis ............................................................................................................ 84
Timolol ........................................................................................................................ 84
iv
Tooth .......................................................................................................................... 84
Tracheostomy ............................................................................................................. 85
Trial of Labor .............................................................................................................. 85
Trigonella .................................................................................................................... 85
Tuberculosis, Meningeal............................................................................................. 86
Tuberculosis, Pulmonary ............................................................................................ 86
Tumor Lysis Syndrome............................................................................................... 87
Urinary Bladder Neoplasms ........................................................................................ 87
Urinary Diversion ........................................................................................................ 87
Urological Manifestations ........................................................................................... 88
Uterine Prolapse ......................................................................................................... 88
Venous Thrombosis.................................................................................................... 89
Vesicovaginal Fistula .................................................................................................. 89
Wounds and Injuries ................................................................................................... 89
Appendix I : Author Index.................................................................................................. 91
Appendix II : List of EMR Journals Indexed in IMEMR (by country) ........................... 111
Appendix III : List of EMR Journals Indexed in IMEMR (by Title) ................................. 127
v
IMEMR Current Contents
Rationale
The Index Medicus for the WHO Eastern Mediterranean Region (IMEMR) has sustained its indexing
policy, which has made it a vital current awareness information tool, for technical staff of the Regional
Office, health care staff, and medical professionals who are able now to access heath literature
published in the Region as soon as it is published. A document delivery service to support the Index has
also been activated which will enable any user to acquire a copy of any article listed in the Index.
The cumulative version of the Index Medicus is available now on the Internet as part of EMRO web site.
A CD-ROM version of the same is also being provided upon request.
Scope and Coverage
The IMEMR Current Contents is issued on a quarterly basis including the most recent articles added to
1
Index Medicus for the Eastern Mediterranean Region (IMEMR) Database .
Indexing Level
Each article has been indexed and assigned to a “Main Heading”, plus added headings according to the
Medical Subject Headings (MeSH) list of the National Library of Medicine (NLM). Up to five added
headings (including the respective country) have been allowed. Subheadings (or qualifiers) are used in
indexing to qualify MeSH headings by pinpointing some specific aspects of the concept represented by
the heading, e.g. “LIVER-Drug Effects” indicates that the article is not about the liver in general, but
about the effect of drugs on the liver.
Organization of the IMEMR
Subject Index
The Index is organized in alphabetical order, according to the Main Subject Headings (MeSH). In most
cases one main subject is assigned to each article. Under the main subject, entries are sorted by
Subheading in alphabetical order also. Each entry includes the bibliographic information of the article
e.g. title of the article, author(s), first author’s affiliation, journal title, year (date of publication), volume
number, issue number, page numbers, number of references, subject descriptors and geographic
descriptors. Abstracts have been added and are searchable on the database on the Internet. (as shown
in Figure 1)
Author Index
The IMEMR includes the author’s index, which also indicates the subjects covered by each author.
(Appendix I)
List of EMR Journals by Country
The IMEMR includes an updated list of EMR Journals, which are indexed in the index. The list is sorted
in alphabetical order by the country of publication, which also indicates the number of journals in each
country. (Appendix II)
List of EMR Journals by Title
The IMEMR includes an updated list of EMR Journals, which are indexed in the index. The list is sorted
in alphabetical order by journal’s title, which also indicates the status of indexing for each journal.
(Appendix III)
Computer facilities
The Current Contents has been produced using the UNESCO WINISIS package. Countries or journals
publishers interested in a subset of the database may be provided with data sets in WINISIS format
upon request.
1
Including the countries of Afghanistan, Bahrain, Djibouti, Egypt, Islamic Republic of Iran, Iraq, Jordan, Kuwait,
Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arabia, Somalia, Sudan, Syrian
Arab Republic, Tunisia, United Arab Emirates, Yemen vii
Availability of photocopies
Photocopies of articles cited in IMEMR may be obtained from EMRO Library free of charge upon
request.
Availability on the Internet
This issue, as well as all forthcoming issues, will appear in WHO/EMRO web site on the Internet, as part
of the complete edition of the Index. Internet address is http://www.emro.who.int/HIS/VHSL/Imemr.htm Antibodies, Antinuclear
immunology
Main Subject Heading
Subheading
Title
Evaluation of anti-DS DNA antibodies in anti-nuclear antibody positive Omani patients.
Author(s)
Alnaqdy, Adel; Al Busaidy, Juma; Hassan, Batool
E-mail:[email protected]
First author's e-mail address
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Microbiology and Immunology
Pakistan Journal of Medical Sciences 2007; 23 (2): 211-215 (22 ref.)
First author's affiliation
No. of References
Journal Title
Year
Volume
Pages
Issue
Descriptors
Keywords: Arthritis, Rheumatoid-diagnosis; Lupus Erythematosus, Systemic-diagnosis; Enzyme-Linked
Immunosorbent Assay; Crithidia; Fluorescent Antibody Technique
Abstract
Abstract: To study the correlation between enzyme linked Immunosorbent assay [ELISA] and immunofluoresencent
[IF] anti-dsDNA antibody measurement in different diseases. One hundred and forty sera from patients with systemic
lupus erythematosus [SLE, n=40], rheumatoid arthritis [RA, n=30], disease control [n=40] and from healthy control
subjects [n=30] were included. Using the ELISA, serum anti-dsDNA was detected in 24/40 [60%] SLE, 5/30 [16.6%]
RA, 9/40 [22.5%] disease controls and 1/30 [3.3%] of normal healthy controls. When IF assay was employed, anti-ds
DNA antibodies were detected in 16/40 [40%] SLE, 3/30 [10%] RA, 5/40 [12.5%] disease controls but none in the
normal subjects. These results suggest that both ELISA and IF techniques can be used for the measurement of antids DNA antibodies in clinical laboratories and, these antibodies are not unique to SLE. Figure (1): Sample of IMEMR citation
viii
Subject Index
IMEMR Current Contents
Subject Index
ABO Blood-Group System
Frequency of ABO, subgroup ABO and Rh [D] blood groups in major Sudanese ethnic groups.
Hassan, Fathelrahman Mahdi
E-mail:[email protected]
Sudan University of Science and Technology - College of Medical laboratory Science
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 21-23 (21 ref.)
Keywords: Rh-Hr Blood-Group System
Abstract: There are differences in the distribution of ABO, subgroup ABO and Rh [D] blood groups in different
populations of the world. Relatively little information is available about blood group distributions in Sudanese
population. To see the frequency of ABO, subgroup ABO and Rh [D] blood groups in major Sudanese ethnic groups
[Danagla, Shaygia and Gaaleen]. Blood testing for ABO, subgroup ABO and Rh [D] typing was done over six months,
in 300 unrelated individuals, from both genders. Blood samples were collected from students of the college of medical
laboratory science - Sudan University of Science and Technology using finger prick method and following routine slide
method. Blood group [O] was the most predominant [52.7%] in both Rh positive and negative subjects, followed by
blood group A, B and AB. Majority [98.0%] of the subjects were Rh [D] positive and only 2% were Rh negative. The
predominant subgroup of ABO was A2 [14.1%]. The frequency of ABO blood groups in both Rh positive and negative
subjects among the major Sudanese ethnic group was similar to that reported from neighbouring regions.
Accidents, Aviation
To err is human-case reports of two military aircraft accidents: possible mechanisms of human
failure.
Dikshit, Mohan B.
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Physiology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 120-125 (12 ref.)
Keywords: Military Personnel; Wounds and Injuries; Environment
Abstract: It has been postulated that pilot error or in-flight incapacitation may be the main contributory factors to 7080% of aircraft accidents. Two fatal aircraft accidents are presented in which either of the above possibilities may have
played a role. The first case report describes an erroneous decision by a fighter pilot to use a seat position adjustment
of the ejection seat leading to fatal injuries when he had to eject from his aircraft. Injuries to the body of the pilot, and
observations on the state of his flying clothing and the ejection seat were used to postulate the mechanism of fatal
injury and establish the cause of the accident. The second case report describes the sequence of events which
culminated in the incapacitation of a fighter pilot while executing a routine manouevre. This resulted in a fatal air crash.
Possible contributions of environmental factors which may have resulted in failure of his physiological mechanisms are
discussed.
Accidents, Traffic
Smashed to pieces: a patient's view of a road traffic accident.
Freeman, Helen
E-mail:[email protected]
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 133-135
Keywords: Wounds and Injuries; Intensive Care Units; Patients
mortality
Life loss and disability from traffic accidents: it is imperative we all act now.
Al Lamki, Lamk
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 1-5 (23 ref.)
Keywords: Mortality; Disability Evaluation; Safety
1
IMEMR Current Contents
Subject Index
Acrocallosal Syndrome
Caudal regression syndrome with partial agenesis of the corpus callosum and partial lobar
holoprosencephaly: case report.
Al Hashami, Hilal; Bataclan, Maria F.; Mathew, Mariam; Krishnan, Lalitha
Sultan Qaboos University Hospital - Department of Child Health
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 89-93 (11 ref.)
Keywords: Holoprosencephaly; Pregnancy in Diabetics; Hyperglycemia-complications; Syndrome
Abstract: Caudal regression syndrome is a rare fetal condition of diabetic pregnancy. Although the exact mechanism
is not known, hyperglycaemia during embryogenesis seems to act as a teratogen. Independently, caudal regression
syndrome [CRS], agenesis of the corpus callosum [ACC] and partial lobar holoprosencephaly [HPE] have been
reported in infants of diabetic mothers. To our knowledge, a combination of all these three conditions has not been
reported so far.
Adnexal Diseases
ultrasonography
Review of gray-scale ultrasonographic findings: a valuable guide to suspect adnexal torsion.
Arab, Maliheh; Tehranian, Afsaneh; Mohammadi, Akram Ghara; Hashemieh, Mojgan
E-mail:[email protected]
Shahid Beheshti University of Medical Sciences - Imam Hossein Hospital - Department of Ob and Gynecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 300-303 (24 ref.)
Keywords: Adnexal Diseases-diagnosis; Ovary-ultrasonography; Torsion, Mechanical; Retrospective Studies
Abstract: To report preoperative gray-scale sonographic characteristics of adnexal Torsion. In a retrospective multicentric study in 20 hospitals, 148 out of 3303 adnexal mass operations, proved histopathologically as Adnexal Torsion,
were reviewed regarding age, involved side and gray-scale abdominal sonographic findings. Torsion occurred in 5% of
benign adnexal surgeries. Mean age was 29 [SD=12], Mean mass diameter was 9 cm and they mostly revealed a
cystic pattern [84%]. Free peritoneal fluid was seen in 29%. Right-sided involvement was shown in 62%. Gray-scale
sonographic findings are valuable besides clinical findings to suspect adnexal Torsion.
Aircraft
Re: to err is human: case report of two military aircraft accidents: possible mechanisms of
human failure.
Masters, Ken
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Medical Education Unit
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 278-279 (1 ref.)
Keywords: Accidents; Military Personnel
Albinism, Oculocutaneous
Oculocutaneous albinism associated with axenfeld's anomaly: three case reports.
Keshav, B.R.; Mohammed, Mahmood J.; Mahmood, Nasir
E-mail:[email protected]
Sur Hospital - Department of Ophthalmology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 111-113 (8 ref.)
Keywords: Mesoderm-abnormalities; Consanguinity; Comorbidity
Abstract: Oculocutaneous albinism and anterior mesodermal dysgenesis are well-known heritable conditions, but
their occurrence in association has only been rarely reported. We present cases of three siblings of a family with
identical presentation suggesting that this association may be more than just a coincidence. This association is worth
noting, as this could be one of the causes of ocular morbidity and poor vision in oculocutaneous albinism.
2
IMEMR Current Contents
Subject Index
Algae
Biological importance of marine algae.
El Gamal, Ali A.
E-mail:[email protected]
King Saud University - College of Pharmacy - Department of Pharmacognosy
SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 1-25 (236 ref.)
Keywords: Biological Products; Seawater-microbiology; Oceans and Seas
Abstract: Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that might
represent useful leads in the development of new pharmaceutical agents. Algae can be classified into two main
groups; first one is the microalgae, which includes blue green algae, dinoflagellates, bacillariophyta [diatoms]. etc., and
second one is macroalgae [seaweeds] which includes green, brown and red algae. The microalgae phyla have been
recognized to provide chemical and pharmacological novelty and diversity. Moreover, microalgae are considered as
the actual producers of some highly bioactive compounds found in marine resources. Red algae are considered as the
most important source of many biologically active metabolites in comparison to other algal classes. Seaweeds are
used for great number of application by man. The principal use of seaweeds as a source of human food and as a
source of gums [phycocollides]. Phycocolloides like agar agar, alginic acid and carrageenan are primarily constituents
of brown and red algal cell walls and are widely used in industry.
Alkaloids
isolation and purification
Bioactive alkaloids produced by fungi I. updates on alkaloids from the species of the genera
boletus, fusarium and psilocybe.
Mahmood, Zafar Alam; Ahmed, Syed Waseemuddin; Azhar, Iqbal; Sualeh, Mohammad; Baig, Mirza Tasawer; Zoha,
S.M.S.
E-mail:[email protected]
University of Karachi - Faculty of Pharmacy - Department of Pharmaceutics
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 349-357 (60 ref.)
Keywords: Basidiomycota-metabolism; Psilocybe-metabolism; Fusarium-metabolism
Abstract: Fungi, in particular, are able in common with the higher plants and bacteria, to produce metabolites,
including alkaloids. Alkaloids, along with other metabolites are the most important fungal metabolites from
pharmaceutical and industrial point of view. Based on this observation, the authors of this review article have tried to
provide an information on the alkaloids produced by the species of genera: Boletus, Fusarium and Psilocybef from
1981-2009. Thus the review would be helpful and provides valuable information for the researchers of the same field .
Amino Acids
urine
Prevalence of statin use in type 2 biabetes mellitus and/or hypertensive patients at risk of
coronary heart disease in Shamiya family practice health center-kuwait.
Al Mutairi, Ghaida'a F.; Al Baghli, Amani A.; Abdul Halim, Ibrahim M.; Abdul Jalil, Huda K.; Karraz, Samer A.; Ali,
Seham A.
Ministry of Health - International Shamiya Family Practice Health Center - Department of Primary Health Care
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 685-690 (22 ref.)
Keywords: Diabetes Mellitus, Type 2; Hypertension; Coronary Disease; Community Health Centers; Prevalence
Abstract: Hyperlipidemia represents an important risk factor in the development and progression of coronary heart
disease. Statin, as a lipid-lowering therapy, is associated with a significant reduction in the risk of primary and
secondary cardiovascular events. To determine the prevalence of statin use in patients with type 2 diabetes mellitus,
and/or hypertensive patients at high risk of coronary heart disease. The study design was cross sectional descriptive
one that was carried out in Shamiya primary health care center-Kuwait. All patients with type 2 diabetes and/or
hypertension attended for follow-up during the study period were potentially eligible for the study if their age was</=30
years and free from cardiovascular disease. Recruitment effort revealed 265 diabetic and 155 hypertensive patients.
The study questionnaire included personal characteristics, clinical data, statin use, in addition to biochemical
investigations, Framingham risk assessment equation was used to stratify hypertensive patients into low, intermediate
and high coronary heart disease risk groups. Patients in intermediate risk group were re-evaluated for indication of
statin use by counting the number of risk factors they had. Overall, borderline and high lipid profiles were detected in
3
IMEMR Current Contents
Subject Index
44.3%, 88.3%, 78.1% and 33.5% of the studied subjects for total cholesterol, HDL-C, LDL-C and triglycerides
respectively. The total number of hypertensive patients in whom statin was recommended was 26 patients [10 high risk
category and 16 intermediate risk category]. Statin was used by 45 diabetic patients [17%] and 9 hypertensive patients
[34.6%]. It was freely supplied by the government for 59.3% of patients [68.1% of Kuwaiti versus 0.0% for Non-Kuwaiti
patients]. Statin was significantly under-used in diabetic and hypertensive patients at risk of coronary heart disease in
primary health care. A multidimensional intervention program is necessary to combat barriers to adequate treatment of
high-risk patients including patient, physician and health care system.
Anemia
epidemiology
Anaemia prevalence and associated sociodemographic and dietary factors among Palestinian
adolescents in the West Bank.
Mikki, N.; Abdul Rahim, H.F.; Stigum, H.; Holmboe Ottesen, G.
E-mail:[email protected]
University of Oslo - Institute of General Practice and Community Medicine - Section of Preventive Medicine and
Epidemiology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 208-217 (26 ref.)
Keywords: Prevalence; Socioeconomic Factors; Diet; Questionnaires; Hemoglobins; Anthropometry
Abstract: Anaemia still persists among children and women of childbearing age in Palestine. We investigated the
prevalence of anaemia and associated factors among Palestinian school adolescents [aged 13-15 years] in Ramallah
and Hebron governorates. Haemoglobin levels were measured to assess the prevalence of anaemia. The prevalence
of anaemia was significantly higher in Hebron than in Ramallah among boys [22.5% versus 6.0% respectively], while
among girls the figures were similar [9.2% and 9.3% respectively]. Linear binomial regression analysis showed that
among boys, anaemia was independently associated with residence in Hebron and higher standard of living, while
among girls, anaemia was associated with higher father's education. Consumption of iron-rich foods, as recorded in
food frequency questionnaires, had no significant effects on anaemia prevalence in both boys and girls.
Anemia, Iron-Deficiency
diagnosis
A new valid formula in differentiating iron deficiency Anemia from beta thalassemia trait.
Keikhaei, Bijan
E-mail:[email protected]
Ahwaz Jondishapour University of Medical science - Research Center for Thalassemia and Hemoglobinopathy
Pakistan Journal of Medical Sciences 2010; 26 (2): 368-373 (25 ref.)
Keywords: beta-Thalassemia-diagnosis; Sensitivity and specificity; Predictive Value of Tests
Abstract: To compare the validity of a new index [HbxRDWx100/ [RBC] 2xMCHC] with twelve discriminating
functions [DFs] to differentiate iron deficiency anemia [IDA] and beta-thalassemia trait [beta-TT]. A total of 823 patients
[317 IDA and 506 beta-TT] aged 15 to 35-year-old were enrolled in this study. The diagnostic sensitivity, specificity and
other validity parameters were calculated to assess the diagnostic reliability of the novel index [Keikhaei index [KI]] visa-vis the other published DFs [Mentzer Index [MI], Green and King Index [G and KI] ,red cell distribution width index
[RDWI], England and Fraser Index [E and FI], Bessman and Feinstein index [B and FI] , Telmissani et al index [TI],
Srivastava and Bevington index [S and BI], Shine and Lal index [S and LI], Ricerca et al index [RI], Ehsani et al index
[EI], Sirdah et al index [SI], and Red Blood Cell Count [RBC] were calculated in all patients. All thirteen DFs didn't have
the sensitivity and specificity of 100%. The KI, RDWI, G and KI and E and FI showed the most sensitivity and
specificity for both IDA and TT; moreover, the lowest reliable indices belonged to B and FI, S and LI and RI. According
to Youden's index [YI], DFs in the order of highest to lowest were KI>G and KI> RDWI>E and FI>RBC>M
I>EI>TI>SI>S and BI>RI>S and LI>B and FI.
Angioplasty, Transluminal, Percutaneous Coronary
Percutaneous coronary intervention in unprotected left main coronary artery disease.
Ahmed, Hafeez; Tai, Javed Majid; Dhakam, Sajid
E-mail:[email protected]
The Aga Khan University Hospital - Department of Medicine
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 287-288 (5 ref.)
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Keywords: Coronary Angiography; Coronary Vessels; Shock, Cardiogenic
Abstract: Percutaneous coronary intervention for unprotected left main coronary artery disease is potentially an
important intervention in surgically unstable patients. A detailed review of medical record and visual analysis of
coronary angiography and PCI procedure was undertaken. The study was conducted at the Aga Khan University
Hospital, from January 2003 to December 2007. Patients included in the study had unprotected > 70% left main
stenosis with ongoing ischemia, considered unsuitable for surgical revascularization. A total of 9 patients were included
with a mean age of 70.1 years. Six patients had cardiogenic shock. Eight patients had bifurcation lesion. Simultaneous
kissing stenting technique was used in 4 patients. There were 4 in-hospital deaths while 5 patients were alive at
discharge. All 4 patients who expired had cardiogenic shock. Four patients were alive at a mean follow-up of 17
months. PCI turned out to be an alternative therapeutic option for unprotected left main coronary artery disease when
surgery is declined.
Anodontia
Oral stereognostic ability in hypodontia patients.
Ahmed, Bilal; Mirza, Kamran Masood; Butt, Amir Mehmood; Hussain, Mehmood; Yazdanie, Nazia
E-mail:[email protected]
University of the Faisalabad - Department of Prosthodontics and Oral Implantology
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 14-17 (20 ref.)
Keywords: Case-Control Studies; Stereognosis; Perception
Abstract: Hypodontia is congenital absence of one or more, but not all, of the normal complement of teeth. It is one
of the most frequent alterations of human dentition. Hypodontia either alone or association with craniofacial
developmental disorders can pose speech and masticatory dysfunctions along with aesthetic and functional problems.
Oral Stereognostic ability can be used to diagnose and predict the prognosis of different treatment modalities in
hypodontia patients. To compare oral Stereognostic ability in hypodontia patients with those having normal dentition.
Case Control study, conducted in the Department of Prosthodontics, de'Montmorency College of Dentistry/ Punjab
Dental Hospital, Lahore, Pakistan. Forty hypodontia subjects were selected. Forty dental students of third and final
year with normal dentition were selected as controls. Oral Stereognostic ability scores were calculated using specific
test samples for both groups. This study showed that oral Stereognostic ability scores were reduced in hypodontia
subjects with a significant p value<0.001. It confirms that hypodontia subjects had some difficulty in perceiving the intra
oral objects. Oral Stereognostic ability was impaired in hypodontia subjects; correction at early age might improve the
case.
Anticholesteremic Agents
therapeutic use
Hypocholesterolemic and antiatherosclerotic effect of Artemisia aucheri in hypercholesterolemic
rabbits.
Dinani, N. Jafari; Asgary, S.; Madani, H.; Naderi, Gh.; Mahzoni, P.
Isfahan University of Medical Sciences - Isfahan Cardiovascular Research Center
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 321-325 (17 ref.)
Keywords: Artemisia; Atherosclerosis-drug therapy; Phytotherapy; Rabbits; Hypercholestrolemia-drug therapy
Abstract: Atherosclerosis which results from gradual deposition of lipids in arteries is a leading cause of mortality
worldwide. Diet is one of the most important factors underlying atherosclerosis. High-cholesterol diets enhance
atherosclerosis and vegetarian diets are known to slow down the process. Artemisia aucheri is a herb of the Composite
family. Many species of Artemisia have proven hypolipidemic and antioxidant properties. This study determine the
effects of Artemisia aucheri on lipoproteins and atherosclerosis in hypercholesterolemic rabbits. Fifteen male rabbits
were randomly divided into three groups. Normal diet group, high-cholesterol diet group [1% cholesterol] and Artemisia
aucheri group [1% cholesterol diet supplemented with 100 mg/kg body weight the Artemisi aucheri every other day].
Biochemical factors were measured at the start, end of the first and second months of the study. At the end of the
study, the aorta were removed for assessment of atherosclerotic plaques. The results indicate that Artemisia aucheri
significantly reduced the level of total cholesterol, LDL cholesterol and triglycerids and increased HDL cholesterol. The
degree of atherosclerotic thickness was significantly reduced in the treated group. Therefore, Artemisia aucheri is one
of the useful herbal medicine for preventation of atherosclerosis and more studies in this regard is recommended.
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Antidepressive Agents
pharmacology
Acute effects of serotonergic antidepressants on tryptophan metabolism and corticosterone
levels in rats.
Bano, Samina; Gitay, Mehnaz; Ara, Iffat; Badawy, Abdulla
E-mail:[email protected]
University of Karachi - University of Wales Institute Cardiff - Department of Biochemistry
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 266-272 (45 ref.)
Keywords: Corticosterone-blood; Tryptophan-metabolism; Brain-metabolism; Serotonin-biosynthesis; Liverenzymology; Rats, Wistar
Abstract: The aim of present study is to see the effects of antidepressants in relation to tryptophan metabolism and
disposition and to know whether they share any common mechanism of action in this regard. These are the
monoamine oxidase inhibitor [moclobemide], atypical tricyclic [tianeptine], selective serotonin reuptake inhibitors
[SSRIs] namely sertraline and citalopram and an herbal St John's Wort [SJW]. Liver tryprophan pyrrolase activity,
serum tryptophan, corticosterone and brain indoles were determined after drug administration in Albino Wistar rats at a
dose of 10mg/kg. All five antidepressants inhibited tryptophan pyrrolase activity. Serum total tryptophan concentrations
were increased by 19% and 33% by tianeptine and moclobemide respectively, however 34% decrease in total
tryptophan was observed after SJW administration. Free tryptophan was increased by all the drugs being maximum
[65% P<0.001] by sertraline and minimum [15%, P<0.05] by tianeptine. Corticosterone levels were significantly
[P<0.01] decreased by 52 and 58 percent by citalopram and St John's Wort respectively. By contrast an increase by
16% was observed by tianeptine. It was also observed that all the drugs increase brain tryptophan by 21-61 percent
but increases in 5-hydroxytryptamine [5-HT] were observed only by two drugs that is moclobemide and SJW, however
in comparison increases were greater [68%] after SJW administration. 5-hydroxyindoleacetic acid [5HIAA]
concentrations were increased by 45-64% by all other drugs except tianeptine and moclobemide. It is concluded that
attenuation of peripheral tryptophan metabolism and elevation of brain tryptophan contributes to the mechanism of
action of antidepressants of different classes and pharmacological profile tested.
Antigens, CD95
blood
High concentration of serum soluble fas in patients with head and neck carcinoma: a
comparative study before and after surgical removal of tumor.
Habibagahi, Mojtaba; Jaberipour, Mansooreh; Fattahi, Mohammad Javad; Hashemi, Seyed Baslr; Shariati, Mahmood
Shiraz University of Medical Sciences - lmmunotherapy Laboratory - Department of Immunology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 21-26 (30 ref.)
Keywords: Antigens, CD95-diagnostic use; Fas Ligand Protein-blood; Alternative Splicing; Fas Ligand Proteindiagnostic use; Head and Neck Neoplasms-blood; Head and Neck Neoplasms-surgery; Prognosis; Enzyme-Linked
Immunosorbent Assay
Abstract: Alternative splicing of the Fas transcript can produce a natural secreted isoform of this molecule. Some
cancer cells can also produce soluble Fas [sFas] which may have suppressive effects on the immune system's antitumor response. Elevated concentrations of sFas have been detected in the sera of patients with different
malignancies. The concentrations of sFas in sera of patients with head and neck carcinoma [HNC, n=98] and healthy
individuals [n=30] were measured by Sandwich ELISA and compared to values obtained six months after surgical
removal of the tumor [n=48]. Data were correlated with different clinical findings of the patients. sFas concentrations in
the sera of HNC patients were found to be significantly higher in patients with different tumor stages. sFas
concentration did not correlate with age or tumor invasiveness, however a higher concentration of sFas was found in
the sera of patients who had higher tumor grades. Surgical removal of tumors in patients resulted in a substantial
decrease in sFas concentration. The initial rise in sFas concentration in the sera of HNC patients and its consequent
decrease could be regarded as a sign of tumor suppressive mechanisms. Additional studies are needed to fully
elucidate this mechanism however these findings might show the prospective use of such biomarkers to determine
disease prognosis and even immunotherapeutic applications.
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Antihypertensive Agents
analysis
Determination of mirtazapine in spiked human plasma and tablets by first derivative
spectrofluorimetric method.
Youssef, Rasha M.
E-mail:[email protected]
University of Alexandria - Faculty of Pharmacy - Department of Pharmaceutical Analytical Chemistry
SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 45-49 (20 ref.)
Keywords: Mianserin-analoges and derivatives; Spectrometry, Fluorescence; Tablets; Mianserin-analysis
Abstract: A sensitive first derivative spectrofluorimetric method [[1]D-spectrofluorimetry] was developed for the
determination of mirtazapine. Calibration graph for mirtazapine determination was established using the first derivative
amplitudes of the mirtazapine emission spectrum [lamda[ex]= 314 nm] in 0.1 M sulphuric acid measured at 375-435
nm from peak to peak, as the analytical signals. Moreover, the ratio of [1]-spectrophotometric peak amplitudes at these
wavelengths was calculated and used for the detection of the presence of interferences. Linearity range was found to
be between 1 and 40 ng ml[-1] with correlation coefficient [r] = 0.9999. The limit of quantitation [LOQ] was 1.0 ng ml[-1]
and the limit of detection [LOD] was 0.2 ng ml[-1]. The proposed method was validated according to ICH; and it has
been applied for the drug determination in human plasma without prior extraction and in tablets. The proposed
method's accuracy, reproducibility, selectivity and simplicity suggest its application in quality control analysis of the
drug.
Antineoplastic Agents, Phytogenic
Effect of inganen anticancer properties on microtobule organization.
Khaleghian, Ali; Riazi, Gholam Hossein; Ghafari, Mahmoud; Rezaie, Marzieh; Takahashi, Akira; Nakaya, Yutaka;
Nazari, Hossain
Semnan University of medical science - Department of Biochemistry and Hematology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 273-278 (32 ref.)
Keywords: Euphorbia-chemistry; Microtubules-chemistry; Microtubules-drug effects; Polymers-chemistry;
Spectrometry, Fluorescence
Abstract: Euphorbia tirucalli [Euphorbiaceae family] an environmental risk factor for Burkitt's lymphoma also has
pharmacological activities. In the northeast of region in Brazil its latex is used as an antimicrobial, antiparasitic in the
treatment of coughs, rheumatism, cancer and other disease as folk treatment. The prevalent constituents of this plant
latex are diterpenes from the Inganen types [ingenol esters] as well as the tigliane [phorbol esters]. Scientifically, there
is not any data till now about anticancer effects of the Euphorbia tirucalli Linn., since the Ingenol esters have already
presented tumor-promoting ability. Microtubules [MTs], and cytoskeletal proteins are essential in eukaryotic cells for a
variety of functions, such as cellular transport, cell motility and mitosis. Single Inganen in cytoplasm can interact with
these proteins and affect on their crucial functions. In this study, we showed the effects of Inganen on MT organization
using ultraviolet spectrophotometer and fluorometry. The fluorescent spectroscopy showed a significant tubulin
conformational change at the presence of Inganen which decrease polymerization of tubulin as well as the ultraviolet
spectroscopy results. The aim of this study is to find the potential function of Inganen for treatment of cancer in cells
and human organs.
Apiaceae
Antibacterial agents from the seeds of Peucedanum zenkeri L. [Umbelliferae].
Mbah, James A.; Gatsing, Donatien; Efange, Simon M.N.
University of Buea - Department of Chemistry
Pakistan Journal of Medical Sciences 2010; 26 (2): 314-318 (17 ref.)
Keywords: Anti-Bacterial Agents; Seeds
Abstract: In a search for natural substances with potential for the treatment of typhoid fevers and urogenital
infections, the methylene chloride extract of the seeds of Peucedanum zenkeri was investigated. The extract was
subjected to column chromatography leading to the isolation of seven compounds. Their structures were determined
using modern 2D NMR techniques and by comparison with published NMR data. These compounds were tested
against Salmonella typhi, Salmonella paratyphi B, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae
and Staphylococcus aureus, using both agar diffusion and broth dilution techniques. The compounds isolated were
umbelliprenin [1], prangenin [2], imperatorin [3], isopimpinellin [4], bergapten [5], cnidilin [6] and stigmasterol [7].
Among the above seven compounds, only two [1 and 2] exhibited antibacterial activity. For compound 1, the MIC value
was 300 micro g/ml against P. aeruginosa, S. aureus, S. typhi and S. paratyphi B. For compound 2, the MIC values
varied between 200 and 300 micro g/ml against all the bacteria strains tested. These data suggest that Peucedanum
7
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Subject Index
zenkeri seed extract contains antibacterial agents which are active against Salmonella species causing typhoid and
paratyphoid fevers, and some bacteria strains causing urogenital infections. The antibacterial activity of compound 2
appears to be due to the epoxide group present in its structure.
Apnea
Fentanyl and midazolam induced respiratory arrest and neuromuscular paralysis during day
care surgery: a case report.
Khan, Rashid M.; Kaul, Naresh; Neelakanthan, Punnuvella H.
Khoula Hospital - Department of Anesthesia
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 255-257 (8 ref.)
Keywords: Paralysis; Fentanyl; Midazolam; Ambulatory Surgical Procedures; Lipoma-surgery; Anesthesia, Local
Abstract: We report a 44 year-old, American Society of Anesthesiologist Class I [ASA I], female patient scheduled
for elective excision of a small lipoma of the left thigh. She went into a 90 minute apnea and complete muscle paralysis
as evidenced by the absence of all stimulatory responses by a peripheral nerve stimulator after receiving midazolam
[1.0 mg] and fentanyl [100 micro g] intravenously for sedation and analgaesia. The patient made an uneventful
recovery after 90 minutes. No cause and effect relationship could be established between the administered drugs and
this unusual response.
Appendectomy
methods
Experience of laparoscopic appendecectomies versus open appendecectomies.
Rooh ul Muqim; Khan, Mansoor; Zarin, Mohammad
E-mail:[email protected]
University of Peshawar - Khyber Teaching Hospital and Khyber Medical College - Surgical C Unit
Pakistan Journal of Medical Sciences 2010; 26 (2): 324-328 (18 ref.)
Keywords: Laparoscopy; Prospective Studies; Treatment Outcome; Surgical Wound Infection; Postoperative
Complications
Abstract: To compare the outcome of laparoscopic and open appendecectomies in terms of operative time and postoperative morbidity. This prospective study was done from March, 2008 to March, 2009, at Surgical "C" Unit of Khyber
Teaching Hospital, Peshawar. All consecutive appendectomies [open and laparoscopic] performed over this time were
included. Demographic details, operative time, conversion, infective post-operative complications and delay in
discharge were recorded. The patients were divided into two groups, laparoscopic appendectomies [LA] and open
appendectomies [OA]. A total of 165 appendectomies were performed, 72 in the LA group and 93 in OA group.
Eighteen appendectomies were perforated at the time of operation. The patients' ages ranged from 12-65 years
[median 24 years]. Eighty were males and eighty five were females. Operative time in LA group was longer with mean
duration of 45 minutes [range 35-75 minutes] compared with 35 minutes [range 30-55 minutes] in OA group. A glove
finger was used as extraction bag in 59 [83%] in LA group. LA patients' wound infection was recorded in12 patients,
two out of 72 in LA and 10 out of 93 in OA group. The site of infection was the port of specimen extraction in LA group.
Intra-abdominal abscesses complication was observed in one case in the OA group. LA group had shorter hospital
stay [mean 1.5 days] than [OA] [mean 3.5 days], and early return to normal activity, 8-15 [mean 10.5] days in LA
and15-25 [mean18.5] days in OA. Laparoscopic Appendectomy [LA] is safe and has major benefits like less postoperative pain, decreased wound infection, early hospital discharge and earlier return to work than Open
Appendectomy [OA]. LA is recommended in all patients with acute appendicitis if laparoscopy is not contraindicated.
Attention Deficit Disorder with Hyperactivity
diagnosis
A rare presentation of attention deficit/hyperactivity disorder: a recommendation to be more
alert.
Al Sharbati, Marwan; Al Zaidi, Rashid; Al Naamani, Rahma; Al Futaisi, Amna; Jain, Rajeev
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Behavioral Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 84-88 (16 ref.)
Keywords: Tuberous Sclerosis; Bipolar Disorder; Comorbidity
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Abstract: We report the case of a 7 year-old Omani girl with tuberous sclerosis [TS], attention deficit hyperactivity
disorder [ADHD] and bipolar disorder [BD], at Sultan Qaboos University Hospital [SQUH], Oman. For a year she had
been suffering from hyperactivity, aggression, over talkativeness, insomnia, risk-taking behaviour, distractibility, poor
attention and seizures. This clinical picture evolved slowly, but was progressive in nature. Before the consultation at
her local health centre, she was given four drugs without being properly investigated; she continued to deteriorate. In
SQUH, she showed hyperactive-impulsive behaviour, elation, flight of ideas, preoccupation with self and high selfconfidence. The physical examination revealed multiple hypomelanotic patches all over the body and a shagreen patch
at the sacral area. The electroencephalogram showed generalised epileptic discharges, while brain imaging showed
multiple parenchymal calcified foci in both cerebral hemispheres. Other investigations were normal. She was given
valproate, and then a psychostimulant, methylphenidate, that controlled her state. Our aim in reporting this case is not
only because it is unique, given its rare comorbidity [ADHD, TS and BD], but also to remind our junior colleagues to be
alert to the possibility of an underlying neuropathology when performing clinical examinations and investigations of
children presenting with neuropsychiatric symptoms.
Behcet Syndrome
Behcet's disease associated with hyperthyroidism: case report and review of literature.
Abro, Ali Hassan; Abdou, Ahmed M. Saleh; Al Saleh, Jamal; Ustadi, Abdulla M.; Younis, Nadeem J.; Doleh, Wafa F.
E-mail:[email protected]
Rashid Hospital Dubai
Pakistan Journal of Medical Sciences 2010; 26 (2): 464-469 (38 ref.)
Keywords: Hyperthyroidism; Comorbidity
Abstract: Behcet's Disease is a multi-system, chronic inflammatory disorder characterized by chronic relapsing
course. Its principal manifestations are oral and genital ulcers as well as inflammation of the eyes, skin and joints, while
vascular and neurological complications may results in death. The etiology and pathogenesis of the disease are still
obscure and specific treatment is not available. We report the case history of a patient with Behcet's Disease. He
presented with fever, arthritis and weight loss of 3-week duration. He was also found to have hyperthyroidism, extrapulmonary tuberculosis, and strongyloidiasis. Although, the association between thyroid diseases and auto-immune
connective tissue disorders as well as tuberculosis is well recognized, there had been, to the best of our knowledge, no
reports of Behcet's Disease associated with thyroid dysfunction. However, further studies are required to investigate
any association between Behcet's Disease and thyroid dysfunction.
beta-lactams
Study the effect of antibiotic combination of beta-lactam and aminoglycosid with another group
antibiotic their synergism effect.
Abdullah, Rana M.; Samaan, Samer F.; Al Shwaikh, Arwa M.
E-mail:[email protected]
Uuniversity of Baghdad - College of Education - Department of Biology
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 62-69 (28 ref.)
Keywords: Aminoglycosides-therapeutic use; Anti-Bacterial Agents; Drug Therapy, Combination; Drug Synergism;
Ciprofloxacin-therapeutic use; Pseudomonas Infections-drug therapy; Treatment Outcome; Drug Resistance, Bacterial;
Microbial Sensitivity Tests
Abstract: This study aimed to evaluate the effect of antibiotic combination between beta-lactams and aminoglycosids
with another group of antibiotics. Fifty isolates of Pseudomonas aeruginosa were identified using different microscopic,
cultural characteristics and biochemical tests. Eight isolates [16%] were from burn infections, 20 [40%] from urinary
tract infections, 16 [32%] from burn infections and 6 [12%] from otitis media cases. Antimicrobial susceptibility tests
and minimal inhibitory concentration MIC were performed. Pseudomonas aeruginosa exhibited [100%] resistance to
amoxicillin, amoxicillin/clavulanic acid and cefazolin. While percentages of resistance to carbenicillin, cefotaxime and
ceftazidime were [84%], [80%] and [78%] respectively. Resistance percentages to gentamycin, tobramycin, piperacillin,
amikacin and ciprofloxacin were [52%], [26%], [24%], [6%] and [4%] respectively. All isolates of Pseudomonas
aeruginosa were highly sensitive [100%] to aztreonam, cefepime, imipenem, peofloxacin and ofloxacin. Combinations
of ciprofloxacin with gentamycin and ceftazidime gave interesting results against the local bacterial isolates in reducing
their MIC values. Gentamycin and ceftazidime gave an obvious decrease in MIC values after combination of these
drugs and used against Pseudomonas aeruginosa. The study shows that the combination of beta-lactams and
aminoglycosids with ciprofloxacin is highly effective in treatment of Pseudomonas aeruginosa infections.
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Beverages
microbiology
Microbial assessment of un-bottled synthetic juices sold in Peshawar.
Abid, Hamida; Ali, Javed; Hussain, Arshad
PCSIR Laboratories Complex - Food Technology Centre
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 5-9 (14 ref.)
Keywords: Food Contamination; Food Microbiology; Food Preservation; Microbial Sensitivity Tests
Abstract: Un-bottled synthetic juices are sold by street venders and hawkers raising the concern about their safety.
To examine the quality of un-bottled synthetic beverages from different locations of Peshawar city using standard
techniques. A total of 56 samples of un-bottled synthetic juices were collected from 8 different locations of Peshawar
city and analyzed for Total Plate Count, Total Coliform Bacteria, Total Fecal Coliform bacteria, E. coli, Yeast and
Mould. In all localities, the street vended un-bottled synthetic juices were found hygienically of poor quality as all had
high total plate count which ranged from 2 x 102 to 5 x 107 and total coliform bacteria ranged from < 0.3 to >110
MPN/ml. Total Fecal Coliform ranged from < 0.3 to 110 MPN/ml. The presence of E. coli contamination was found in
[25] 44% samples, while all the analyzed samples were contaminated with yeasts and moulds. All un-bottled synthetic
juices sold on roadside were highly contaminated with disease causing microorganisms. Periodic monitoring of street
beverages should be carried out to make them safe for consumption.
Blepharophimosis
Blepharophimosis-ptosis-epiconthus inversus syndrome in a Pakistani pedigree.
Chaudhry, Tanveer Anjum; Khalid, Mirza Umair; Saleem, Taimur; Khabir, Ahmad
E-mail:[email protected]
The Aga Khan University - Department of Surgery, Section of Ophthalmology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 285-286 (9 ref.)
Keywords: Blepharoptosis; Syndrome; Pedigree; Family
Abstract: Blepharophimosis-ptosis-epicanthus inversus syndrome [BPES] is a rare developmental ocular disorder.
We report this condition affecting 4 members of a Pakistani family across three generations. A 2-year-old girl was
brought to the clinic by her father for the correction of her shortened palpebral fissures. Examination findings were
consistent with BPES. The girl's father, paternal grandfather and paternal aunt also had identical features. The
distance between the medial canthi of the index case was 30 mm, and the lengths of vertical and horizontal palpebral
fissure were 6 mm and 20 mm, respectively. BPES must be considered an important differential diagnosis in patients
presenting with blepharoptosis and blepharophimosis.
Body Composition
Optimum anthropometric criteria for ideal body composition related fitness.
Kilani, Hashem; Abu Eisheh, Asem
E-mail:[email protected]
Sultan Qaboos University - College of Education - Department of Physical Education
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 74-79 (16 ref.)
Keywords: Anthropometry; Physical Fitness; Body Mass Index; Body Weight; Resistance Training
Abstract: The three aims of this study were to establish equations for ideal body composition related fitness to be
used by adults willing to gain optimum body composition related fitness; to predict the possible symmetrical major
muscle circumference, and to compute the ideal body fat percentage [BFP] with ideal body weight [IBW] based on the
body mass index [BMI]. Twenty-four athletes were intentionally selected, with heights of 166-190 cm and aged 20-42
years, according to a judging committee that used modified International Fitness Federation criteria for the Mr. Fitness
competition "super body category". Common anthropometric and body composition measurements were taken for the
following independent variables: body height, upper limb length, lower limb length, thigh length, arm length, shoulder
width, forearm length, shank length, and wrist girth; and for the following dependent variables: circumferences of
shoulder, thigh, waist, hip, chest, biceps, forearm, shank, and neck. Skin fold thickness was measured at three sites by
a Harpenden caliper to calculate BFP. The findings indicate that there was a predictive correlation between major
independent variables and body circumferences. The mean range used to find out the ideal BFP percentage which
was 5.6 +/- 6.7%. The BMI equation used to find the IBW was H2 23.77 +/- 2 SE. Stepwise multiple regressions were
also used to derive predictive equations. The most predictive independent variables were wrist girth and height. It is
suggested that the above equations, the ideal BFP percentage and the IBW be used as criteria in training sessions to
achieve ideal body composition related fitness.
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Body Fluids
The efficacy of workshop on body fluids in health and disease and its impact on nurses training.
Altun, Insaf
E-mail:[email protected]
Kocaeli University - Department of Fundamentals in Nursing
Pakistan Journal of Medical Sciences 2010; 26 (2): 426-429 (23 ref.)
Keywords: Nurses; Knowledge; Education, Nursing; Educational Measurement; Teaching
Abstract: To determine the efficacy of workshop on body fluids in health and disease and its impact on nurses
training. Nurses attended an interactive lecture-based workshop on body fluids in health and disease. Participants had
to accept an invitation to the presentation prior to the training event. They completed a multiple choice question [MCQ]
test, derived from topics covered in the presentation, prior to the lecture. The MCQ test was repeated after the lecture
to assess retention and application of knowledge. Thirty-six nurses participated in the workshop. There was a
significant improvement in mean test scores after the lecture when compared with pre-lecture scores [Mean=30.9,
SD=4.4 vs. Mean=11.7, SD=3.4, p<0.001]. Pre-post data in according to the Kolmogorove-Smirnov test were normally
distributed [Asy mp.sig.05, 0.02]. Lecture based interactive workshop on body fluids in health and disease helps
improve nurses' knowledge. It also helps in overcoming deficiencies in nurses training.
Body Mass Index
[Body mass index and body fat in Lebanese female adolescents].
Fazah, Abdallah; Jacob, Christophe; El Hage, Rawad; Delamarche, Paul; Moussa, Elie
E-mail:[email protected]
University of Balamand - Division of Physical Education - Laboratory of Physiology and Biomechanics of Motor
Performance
LMJ - Lebanese Medical Journal 2010; 58 (2): 97-100 (25 ref.)
Keywords: Adipose Tissu; Obesity-epidemiology; Absorptiometry, Photon
Abstract: The aim of this study is to investigate the relation between body mass index [BMI] and body fat [BF] among
Lebanese female adolescents. 51 Lebanese females aged 12 to 18 years participated in this study. BMI was
calculated as weight/height. Adiposity was measured by dual energy X-ray absorptiometry [DEXA]. Correlation
coefficient of percent body fat [%BF] with BMI is 0.82. Correlation coefficient of fat mass [BF] with BMI is 0.93. The two
linear regression formulas are:%BF=6.89+ [1.1 *BMI] and BF=-0.425+ [129 *BMI]. Correlations of BMI with DEXA
measurements were higher with BF than%BF. For a given BMI, Lebanese girls have a higher than expected%BF.
Based on the current findings, there may be a need to develop new cutoff points. From a public health perspective, this
may considerably increase the prevalence of obesity among Lebanese female adolescents.
Bone Density
Bone mineral density in beta thalassemia major and intermedia, correlation with biochemical
and hormonal profiles.
Rafsanjani, Khadijeh Arjmandi; Azar, Maryam Razzaghy; Shoolami, Leila Zahedi; Vossough, Parvaneh; Modarres,
Aliakbar; Taheri, Nima
E-mail:[email protected]
Iran University of Medical Sciences - Hazrat Aliasghar Hospital, Grant number: 555
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 121-127 (22 ref.)
Keywords: beta-Thalassemia; Cross-Sectional Studies; Osteoporosis; Puberty; Ferritins-blood; Hypogonadism
Abstract: Expansion of bone marrow cavity and decreased cortical and trabecular bone tissues and osteoporosis are
resulted from beta-thalassemia. The aim of this study was to assess bone mineral density [BMD] in patients with beta
thalassemia major and intermedia, and to determine their biochemical and hormonal profiles that may affect BMD. In a
cross sectional study from October 2004 to April 2006, 305 patients [273 thalassemia major [137 males and 136
females] and 32 thalassemia intermedia [13 males and 19 females]] were evaluated for BMD. Dual x-ray
absorptiometry was performed at 3 sites: spine [L2-L4], femoral neck, and radius. Z score< -2.5 was considered as
osteoporosis, and between -1 and -2.5 as osteopenia. Z-scores were calculated according to bone density values
based on age and sex. Patients were grouped according to age 3-6, 6-10, 10-13, 13-16, and over 16 years old. The
stage of puberty was determined according to Tanner staging and its progression was followed. Biochemical and
hormonal profiles of patients were recorded. In thalassemia major, mean age was 14 +/- 6.5 years, and mean BMD Zscore of spine, radius and hip were -2.3 +/- 0.9, -2.8 +/- 1.2, and -1.9 +/- 1.4, respectively. Mean age of patients with
thalassemia intermedia was 13.4 +/- 6.2 years, and the mean Z-score of spine, radius, and hip were -2.1 +/- 0.9, -2.0
+/- 1.3, and -2.3 +/- 1.3, respectively. Hypogonadism was detected in 36% of thalassemia major and 35% of
thalassemia intermedia; but hypothyroidism, diabetes mellitus, and hypoparathyroidism were detected only in
thalassemia major with frequency of 2.8%, 1.8%, and 1.2%, respectively. BMD in spine and radius were significantly
lower in patients with hypogonadism than in patients with normal puberty [P=0.039 and P=0.015, respectively]. Height
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Standard Deviation Score [HSDS] was not significantly different in groups of osteoporosis and normal. Osteoporosis
was seen in all age groups, and was more common in males than females at spine and radius bones [P<0.001]. It was
less common in patients with hypothyroidism, hypoparathyroidism, and diabetes mellitus. BMD Z-Score had significant
correlation with serum ferritin only in radius area [P=0.04], and it had no significant correlation with serum Ca, P, Mg
and Zn. Our results showed that the patients with thalassemia major and intermedia had low BMD. Patients with
hypogonadism and males had lower BMD. Young children also had low bone mass, so early attention is essential.
Breast Neoplasms
The current status of breast cancer among resource-limited countries.
Masood, Shahla
E-mail:[email protected]
University of Florida - College of Medicine Jacksonville - Department of Pathology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 1-4 (21 ref.)
Keywords: Early Detection of Cancer; Culture; Mass Screening; Incidence; Developing Countries; Health Priorities
etiology
Assessment of breast cancer risk factors in asymptomatic hospital staff women aged 32-59: a
descriptive report.
Hamdi, K.; Yahyazadeh, S.H.; Bahoor, F.; Ziaee, F.; Arefi, Sh.; Jafarnia, N.; Asadi, S.
Iran University of Medical Science - Akbarabadi Hospital - Department of Gynaecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 288-293 (23 ref.)
Keywords: Risk Factors; Health Personnel; Questionnaires; Breast Neoplasms-epidemiology
Abstract: Iranian breast cancer patients are relatively younger than their Western counterparts. The objective of the
present study was to investigate risk factors for breast cancer in Iranian women and compare it with other data driven
from other studies. A study was conducted in April 2008 in Tehran, Iran. Demographical data and risk factor related
information, including data from their mammograms were collected using a questionnaire. In all, 109 participants were
interviewed. The mean age of participants was 40.48 +/- 0.56 years. 1.8% of women were unmarried, while 78% were
married and 20.2% were divorced/widowed. The mean age for menarche was 13.34 +/- 1.47 years and 46.89 +/- 4.98
for the menopause, respectively. The mean parity time was 2.36 +/- 1.13 and breastfeeding in women was 23.27 +/14.16 months. About 5.5% of the participants used oral contraceptive as a method for contraception. 8.3% of women
experienced menopause, at the mean age of 46.89 +/- 4.98. 33.3% of menopaused women, used Hormone Replace
Therapy [HRT]. Moreover, 8.3% of women had a positive history of breast cancer in their family. Of those women on
whom mammography was done, 10.1% had breast mass in radiological findings, mostly in favour of fibrocystic change.
In 20.2% of participants, further investigation was advised. The findings of the present study were in accordance with
other studies done in Iran and in some aspects in tune with other studies about breast cancer in other countries.
However, more multicentric larger scale studies should be conducted in Iran to determine a pattern for breast cancer in
Iranian women.
Bundle-Branch Block
etiology
Asymptomatic permanent left bundle branch block [LBBB] complicating diagnostic left heart
catheterisation.
Al Hadi, Hafidh; Sallam, Mansour
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 114-119 (13 ref.)
Keywords: Bundle-Branch Block-diagnosis; Heart Catheterization-adverse effects; Coronary Angiography;
Electrocardiography
Abstract: This case report describes a routine diagnostic left heart catheterisation [coronary angiography,
aortography and left ventriculography] procedure at Sultan Qaboos University Hospital, Oman, which was complicated
by the development of new asymptomatic, but permanent, left bundle branch block that was observed incidentally
towards the end of the procedure. The patient was completely asymptomatic and haemodynamically stable throughout
the procedure and afterwards. Urgent investigations, immediately after the procedure, including routine blood, serial
cardiac troponin I, serial electrocardiograms, chest X-ray, and urgent echocardiography were normal and failed to
show any possible causation of the LBBB. The results of left heart catheterisation showed two vessel coronary artery
disease and severe mitral valve regurgitation. After eight days, the patient went on to have coronary artery bypass
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surgery and mitral valve replacement surgery both of which were successful. To the best of our knowledge, this is the
first case report to describe the occurrence of permanent LBBB after left heart catheterisation. This report describes
the case and reviews the literature for the incidence and implications of such a complication.
Burns
epidemiology
Epidemiology of burn injury in Erbil government: a hospital based study.
Shabila, Nazar P.; Al Hadithi, Tariq S.; Al Tawil, Namir G.; Faidulla, Rawand M.
E-mail:[email protected]
Hawler Medical Uuniversity - College of Medicine - Department of Community Medicine
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 55-61 (18 ref.)
Keywords: Burns-mortality; Age Distribution; Sex Distribution; Body Surface Area; Risk Assessment
Abstract: The aim of this study was to find out the burden of burn injury and identify the high risk groups in Erbil city
which could help in implementing effective preventive measures. The case records of patients with burn injury admitted
to the Emergency Management Center in Erbil city from January 1st 2006 to December 31st 2007 were reviewed. Data
on age and sex of patients, extent and aetiology of burn injury, and monthly and seasonal variations of injury were
extracted from the case records. Out of 1920 burn patients admitted to the hospital; 452 died with an overall mortality
rate of 23.54%; 70 [15.49%] were children and 382 [84.51%] were adults. The mortality rate was significantly higher
among adults than children, 35.30% and 8.35%, respectively [p<0.001] and among females than males, 34.38% and
9.63% respectively [p<0.001], giving a male: female ratio of 0.22:1. The highest mortality rate was among adult
females [47.88%] particularly the 15-29 years age group [53.07%]. The trend of injury and mortality showed fluctuation
with increasing frequencies during the summer months. Flame injury was the main aetiology of burn [94.47%], which
was significantly more common than scald injury among adults compared to children and among females compared to
males. The study reports a high rate of mortality from burn injury with very high total body surface area [TBSA] burned
especially among young adult females, and identifies the significance of burn injury as a public health problem and a
social concern.
Camels
Studies on pituitary [TSH]-thyroid [T3, T4, FT4]-liver axis during seasonal variation at two
different ages of male camel [camelus dromedarius].
Al Kheraije, K.
El-Qassim University - Faculty of Agriculture and Vet. Medicine - Department of Vet. Medicine
Veterinary Medical Journal 2009; 57 (1): 7-22 (52 ref.)
Keywords: Age Factors; Thyroid Gland-anatomy and histology; Thyroid Function Tests; Liver-anatomy and
histology; Liver Function Tests-blood; Cholesterol-blood; Triglycerides-blood; Seasons; Breeding; Male
Abstract: This study was undertaken to investigate the intricate relationship between pituitary, thyroid and liver of
male camel. Thyroids and corresponding livers and blood at two ages during breeding and non-breeding seasons were
collected from slaughter houses. Tissues were used for histological examination and evaluation of T3 and T4 content.
Serum was used for determination of TSR, T3, T4 and FT4. Some fat and protein profiles were estimated. Serum
activity of certain enzymes as ALT, AST, LDH, and ALP were also measured. The data showed that most of the thyroid
follicles were large in old non-breeding and were small in young and old breeding animals. Mild to moderate fatty
infiltration and small to medium sized lipid inclusions were common feature in hepatocytes of all tested animals
especially in old age. TSFI and T3 in old non-breeding were significantly decreased than old breeding. No significant
variation between the different seasons and ages concerning FT4 while a significant decrease in serum T4 was
observed in old non-breeding than young breeding camel. No significant variation in the amount of T3 and T4 in the
liver extracts while thyroid extract obtained from camel in the non-breeding season showed a significant increased in
T4 at both ages than breeding season at any age. Old camel had a significant increased in serum triglyceride, total
lipids and cholesterol than young. No significant variation between the two different seasons and ages concerning total
protein, albumin, globulin, albumin globulin ratio, ALP and LDH. In the breeding season, level of serum AST was
significantly higher in old than young camel, while, old camel during non-breeding season showed a significant
increase in serum ALT than young at any season. It is clearly that the old camel during the non-breeding season
[summer], their physiological activities concerning pituitary [TSH], thyroid hormones [T3 and T4] and liver function
parameters [fat metabolism, ALT and AST] were negatively affected.
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Microbiology
Studies on some salmonella serovars isolated from slaughtered imported camels.
Scharawe, Hala I.; Ibrahim, Hanan M.; Safwat, El Sawy
Veterinary Medical Journal 2009; 57 (1): 23-33 (29 ref.)
Keywords: Abattoirs; Salmonella-isolatin and purification; Prevalence; Lymph Nodes
Abstract: The present study was undertaken to determine the prevalence and distribution of salmonellae from
apparently healthy slaughtered camels in Cairo abattoir. One hundered imported slaughtered camels were examined
for salmonellae. The mesenteric lymph nodes were collected from all animals after slaughtering. In addition to 55
camels were examined by taking muscle swabs [diaphragmatic or abdominal]. Salmonellae were found in 5% of the
mesenteric lymph nodes and in 3.6% of the muscle swabs. Four different serovars were identified, namely salmonella
typhimurium, S.Florida, S.Washington and S.Uganda. antibiogram patteren of 7 isolated salmonella serovars against
16 antibiotics was studied. Plasmid profiles of other S.typhimurium Isolates and other S.typhimurium From other
sources were compared. Public health importance and hygienec measures were discussed.
Cantharidin
poisoning
Cantharidin poisoning due to blister beetle ingestion in children: two case reports and a review
of clinical presentations.
Al Binali, Ali M.; Shabana, Medhat; Al Fifi, Suliman; Dawood, Sami; Shehri, Amer A.; Al Barki, Ahmed
E-mail:[email protected]
King Khalid University - College of Medicine - Department of Child Health
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 258-261 (14 ref.)
Keywords: Beetles; Eating; Infant; Hematemesis
Abstract: Cantharidin is an intoxicant found in beetles in the Meloidae [Coleoptera] family. Ingestion may result in
haematemesis, impaired level of consciousness, electrolyte disturbance, haematurea and renal impairment. Here, we
report two paediatric cases of meloid beetle ingestion resulting in cantharidin poisoning and the clinical presentation of
the ensuing intoxication.
Carcinoma, Basal Cell
pathology
Mast cells in basal cell carcinoma.
Heidarpour, Mitra; Rajabi, Parvin; Heidarpour, Majid; Khalife, Ali
E-mail:[email protected]
Isfahan University of Medical sciences - School of Medicine - Department of Pathology
Pakistan Journal of Medical Sciences 2010; 26 (2): 398-401 (18 ref.)
Keywords: Mast Cells; Proto-Oncogene Proteins C-Kit-analysis
Abstract: Many researchers have been more interested in inflammatory changes in tumor stroma recently. Recent
studies have shown that mast cells are significantly increased in human skin basal cell carcinoma [BCC] and are
associated with tumor aggressiveness. In this study, we compared the number of mast cell population expressing c-kit
in the BCC samples and normal skin. We also evaluated the number of this cell type in infliltrative and noninfiltrative
subtypes of this tumor. Tissue sections containing 30 cases of BCCs and 30 normal skins were prepared and after
staining with c-kit were analyzed for the number of stromal mast cells. Our results indicate that the number of c-kit
positive mast cells was significantly higher in BCC when compared with normal skin [P<0.01], and number of mast
cells in the stroma of infiltrative subtypes of this tumor is higher than noninfiltrative subtypes [p<0.04]. In our study
there wasn't any correlation between sex and age with mast cells count. Our results are in line with previous studies
indicating that mast cell numbers are increased in BCC. In addition, the results suggest that mast cell populations may
contribute to BCC progression. Besides, we demonstrated that this increase in mast cell density was independent of
the patient's ages and sexes.
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Carcinoma, Ductal, Breast
pathology
Association of carcinoma breast: grade and estrogen progesterone receptor expression.
Kamil, Muhammad; Khalid, Imran; Hashim, Hasnah; Biswas, Mrinal; Kaur, Gurjeet; Islam, Rajakul
E-mail:[email protected]
University Sains Malaysia - Advanced Medical and Dental Institute
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 250-252 (15 ref.)
Keywords: Receptors, Estrogen; Receptors, Progesterone; Prognosis
Abstract: To determine the association between histological grade of tumour and estrogen progesterone receptors
[ER/PR] expression in unselected invasive carcinoma of breast in Malaysian patients. An observational study.
Advanced Medical and Dental Institute and Hospital, Kepala Batas, from year 2002 to 2007. Ethical approval from
Ministry of Health of Malaysia was obtained. Retrospective case records of patients presented between 2002- 2007
were reviewed for obtaining information on grade of tumour and expression of ER/PR in unselected carcinoma of
breast patients. Records with missing data were discarded. Out of 195 cases evaluated, 42 cases of grade-l tumour
were recorded of which 08 [19%] tested positive for ER and 34 [81%] tested negative, 86 cases represented grade-ll
tumour of which 33 [38%] tested positive for ER and 53 [62%] were negative for ER, while out of 67 grade-Ill tumours
22 [33%] were positive for ER receptors while 45 [67%] were negative, [chi[2] statistic [df] 4.831, p=0.089]. For PR, 192
cases were evaluated and data was missing for 3 cases on PR status. Grade-l tumour consisted of 39 cases of which
PR +ve represented 07 [17.94%] and 32 [82.05] cases PR -ve; 86 cases were of grade-ll of which 31 [36.04%] were
PR +ve and 55 [63.95%] PR -ve. Sixty seven cases of grade-Ill tumour of which 19 [28.35%] were PR +ve and 48
[71.64] were PR -ve [chi[2] statistic [df]: 4.297; p=0.117]. ER/PR positivity trend was highest for grade-ll tumours
compared to grade-l and grade-l 11 tumours. In general ER positivity was more with grade-ll and grade-Ill tumours
compared to grade I tumours. Although results did not reach statistical significance but there was a trend towards
ER/PR positivity in grade-ll and III tumours. So far, studies from South East Asia reported ER/PR expression more with
low grade tumours.
Carcinoma, Small Cell
pathology
[Small cell neuroendocrine carcinoma of the urinary bladder: report on two cases and review of
the literature].
Chouairy, Camil J.; Salloum, Ali N.; Ghazal, George Y.
E-mail:[email protected]
St George Hospital University Medical Center - Department of Pathology
LMJ - Lebanese Medical Journal 2010; 58 (2): 111-119 (41 ref.)
Keywords: Carcinoma, Small Cell-diagnosis; Carcinoma, Small Cell-DRUG THERAPY; Urinary Bladder Neoplasmspathology; Urinary Bladder Neoplasms-diagnosis; Cystoscopy; Immunohistochemistry
Abstract: Small cell [Neuroendocrine] carcinoma of the urinary bladder is a rare but highly aggressive malignancy.
The neoplastic cells exhibit both neuroendocrine and epithelial differentiation. It is morphologically indistinguishable
from the more common pulmonary small cell carcinoma. It can occur either in association with urothelial [transitional
cell] carcinoma or in a pure form. Presenting signs and symptoms are non specific. Histologically, it can mimic poorly
differentiated urothelial carcinoma and lymphoma. Muscle invasion is almost invariably present at diagnosis and
mortality is mainly due to metastases rather than loco regional recurrence. The optimal therapeutic modality is still
controversial. In this article, we report on two cases occurring in a pure form and we briefly review the published
literature regarding the clinical presentation, morphology, differential diagnosis, prognosis and treatment.
Carnitine
pharmacology
Pharmacological preconditioning with l-carnitine: relevance to myocardial hemodynamic
function and glycogen and lactate content.
Najafi, Moslem; Javidnia, Ali; Ghorbani Haghjo, Amir; Mohammadi, Sadollah; Garjani, Alireza
Tabriz University of Medical Sciences - School of Pharmacy - Department of Pharmacology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 250-255 (25 ref.)
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Keywords: Ischemic Preconditioning, Myocardial; Hemodynamics-drug effects; Glycogen-analysis; Lactic Acidanalysis; Rats; Myscardium-metabolism
Abstract: Carnitine is a vital biologic substance facilitating fatty acids transport into mitochondria for ATP production.
This study was to investigate the effects of pre-ischemic pharmacological preconditioning [PC] with L-carnitine [L-Car]
on myocardial infarct size and cardiac functions in ischemic and reperfused isolated rat heart and meanwhile on left
ventricular glycogen and lactate content. Isolated rat hearts were subjected to 30 min coronary artery occlusion
followed by 120 min reperfusion. The hearts [n=8-12] were perfused with L-Car [0.5-5 mM] only for 15 min before to 10
min after induction of ischemia. Preconditioning of the hearts with L-Car provided concentration-dependent
cardioprotection as evidenced by improved postischemic ventricular functional recovery [developed pressure, left
ventricular end diastolic pressure and coronary flow rate] and reduced myocardial infarct size [p<0.001]. L-Car [2.5
mM] decreased both glycogen [p<0.001] and lactate [p<0.05] content in left ventricle during ischemia compared with
the control. The results of this study demonstrate that L-Car pharmacologically precondition the hearts against
ischemic and reperfusion injury in part by recovery of postischemic ventricular hemodynamic functions, depletion of
glycogen and therefore reduction of lactate accumulation.
Catfishes
Variability of serum biochemistry in wild catfish clarias gariepinus collected from South and
North Cairo area. I. liver and kidney functions.
Rizkalla, Esam H.; Fahmy, Basem A.G.; Fudllalah, Ferial M.N.
Department of Nutritional Deficiency Diseases and Toxicology
Veterinary Medical Journal 2009; 57 (1): 77-96 (59 ref.)
Keywords: Liver Function Tests; Gamma-Glutamyltransferase; Kidney Function Tests; Seasons
Abstract: Fish serum reflects status of many biochemical processes in the metabolism. Many environmental
stressors alter serum biochemical parameters in fishes. Thus, both sexes of Nile catfish, Clarias gariepinus, were
collected from south [Al-Aiat] and north [Barrage] Cairo city to investigate the responses of serum gamma glutamyl
transferase [Y-GT], alkaline phosphatase [ALP], urea, uric acid and creatinine to environment in different seasons.
Different seasonal patterns were reflected for serum biochemical parameters in all fish groups studied. Season
significantly affected the serum ALP in all groups. Male's serum urea and uric acid from the two regions showed
significant seasonal changes in addition to the female's serum urea from Barrage region. For serum creatinine, only
females from Al-Aiat region demonstrated significant seasonal changes. Serum Y-GT did not show any significant
seasonal change in this study.Location effect appeared more evident with serum ALP and urea and to lesser degree
with serum creatinine. Serum Y-GT and uric acid were the lowest parameters affected with the location of samples.
Serum Y-GT, ALP, urea and uric acid were affected by fish sex, while serum creatinine shoved no sigilicant sex
change.All the serum biochemical parameters were effected andy die interactions of season with location and season
with both location and sex, while the interaction of location with sex affected only serum ALP and creatinine. No
change was detected for the effect of season interaction with sex on the serum parameters.
Celiac Disease
diagnosis
Evaluation of endoscopic versus serologic and histopathologic changes in the diagnosis of
celiac disease.
Saeed, Bashar Ali; Strak, Sarkis K.; Al Haroon, Sawsan S.
M.B.Ch.B
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 2-8 (37 ref.)
Keywords: Celiac Disease-immunology; Celiac Disease-pathology; Endoscopy; Sensitivity and Specificity;
Predictive Value of Tests
Abstract: To evaluate the endoscopic versus serologic and histopathologic changes in the diagnosis of celiac disease and to
correlate the endoscopic changes with the degree of mucosal damage. Seventy two patients with symptoms of chronic diarrhea,
38 females whose ages ranged from 11 to 60 years and 34 males whose ages ranged from 10-59 years were tested for antitissue transglutaminase after they underwent upper gastroduodenoscopy. Duodenal mucosa was visualized carefully for any
changes of celiac disease. Four endoscopic biopsies were taken from each patient and sent for histopathologic
examination.Duodenal biopsies were classified according to modified. Marsh's classification. Among the 72 patients who were
enrolled in the study, 28 patients tested positive for anti tissue transglutaminase, 47 patients had histopathologic changes, 26
patients who had both anti tissue transglutaminase and histopathologic changes were classified as celiac patients, among them
19 patients had endoscopic changes. The sensititvity, specificity, positive predictive value and negative predictive value of
endoscopic changes were [73.07%], [86.95%], [76%], and [85.1%], respectively. The endoscopic appearance of the duodenum
may be predictive of the severity of mucosal damage; but overall, the endoscopic changes have a wide range of sensitivity
because the endoscopic findings had been normal in the presence of minor mucosal changes. Anti tissue transglutaminase was
well correlated with histopatholgic changes in celiac disease.
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Cell Differentiation
drug effects
Phorbol myristate acetate [PMA] induced megakaryocytic differentiation of K562 cells from
human chronic myelogenous leukaemia patient.
Naseer, Muhammad Imran; Zubair, Hassan; Ikramullah; Najeebullah; Lee, Hae Young; Kim, Myeong Ok.
Gyeongsang National University
Pakistan Journal of Medical Sciences 2010; 26 (2): 352-357 (25 ref.)
Keywords: K562 Cells-drug effects; Tetradecanoylphorbol Acetate; Megakaryocyte Progenitor Cells-drug effects;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Abstract: To observe the K562 cell line derived from a patient of chronic myelogenous leukemia differentiated into
megakaryocytes by growing in the presence of phorbol myristate acetate [PMA]. The differentiation process of K562
cells was monitored by the expression of a platelet cell marker, CD61 through immunocytochemistry using mouse
alkaline phosphatase antialkaline phosphatase [APAAP] complex employing fast red TR as substrate, crystal violet and
MTT assay used for cell growth analysis. The crystal in the presence of PMA, cells obtained were of large size and
less in number as compared to cells incubated without PMA where they were of smaller size and more in number and
immunochemical reaction used to detect the presence of CD61, a platelet cell marker that is expressed during
differentiation of K562 cells to megakaryocytes. The results showed that the addition of PMA to the growing culture of
K562 cell lines induced differentiation, observed through CD61 expression and increase in cell size and cessation of
proliferation.
Cell Physiological Phenomena
Phenomenological explanation of cell inactivation cross section in terms of direct and indirect
action.
Azooz, Faika A.; Meerkhan, Suaad A.
E-mail:[email protected]
University of Mosul - College of Education - Department of Physics
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 64-73 (23 ref.)
Keywords: DNA Damage; Cross-Sectional Studies; Survival; Radiation; Cells-radiation effects
Abstract: The aim of this study was to use survival curves data for the inactivation of V79 cells and CHO-K1 cells by
protons, neutrons, C12 ions and He3 ions to study the role of direct and indirect action in cell inactivation. A large
number of survival curves for the inactivation of V79 cells by protons, neutrons, and C12 ions and for CHO-K1 cells
inactivated by He3 ions over a wide energy range were taken from published references. Experimental data points
were extracted from the published survival curves using MATLAB [Version 7.0] and fitted to the linear quadratic
equation. The fit parameters were used to calculate the inactivation cross section [segma] at the initial slope, the 2Gy
dose and at 10% survival for each particle type separately. The results, in general, showed that the inactivation cross
section decreases nearly exponentially when increasing the mean free path for primary ionisation [lamda], except in
the case of protons, and to some extent neutrons, where the cross section takes a constant value at specific lamda
values. The cross section increased with increasing linear energy transfer [LET] and also became independent of LET
at specific LET values. The results indicate that the cell damage due to the double strand breaks of DNA caused by
indirect action is much larger than that caused by the direct action.
Central Serous Chorioretinopathy
drug therapy
Role of avastin in management of central serous chorioretinopathy.
Mehany, Shaaban A.; Shawkat, Ahmad M.; Sayed, Mohamed F.; Mourad, Khaled M.
El-Minia University - El-Minia University Hospital - Department of Ophthalmology
Saudi Journal of Ophthalmology 2010; 24 (3): 69-75 (17 ref.)
Keywords: Antibodies, Monoclonal-therapeutic use; Vascular Endothelial Growth Factors A; Angiogenesis Inhibitors;
Prospective Studies; Treatment Outcome
Abstract: To evaluate the short-term safety and efficacy of intravitreal bevacizumab for the treatment of intraretinal or
subretinal fluid accumulation secondary to central serous chorioretinopathy [CSC]. Prospective interventional series
non-comparative study. Department of Ophthalmology, Al-Minya University Faculty of Medicine, Egypt. The study
included 20 eyes of 20 patients with central serous chorioretinopathy [CSC], Out of them 10 eyes with acute CSC
[group I] , 6 eyes with chronic CSC [defined as symptoms present for longer than 6 months] and four eyes with
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Subject Index
recurrent [defined as more than one episode of the disease] chronic and recurrent cases are considered in one group
[group II], all patients were injected with intravitreal Avastin [IVA] 1.25 mg [0.05 mL] of commercially available
bevacizumab [Avastin; Genentech, Inc., San Francisco, CA] as a primary treatment. At baseline and follow up visits
patients had best corrected visual acuity [BCVA], IOP assessment, dilated fundus examination, fundus photography,
fluorescein angiography [FA] and optical coherence tomography [OCT] imaging is used for measurement of central
retinal thickness [CRT]. Main outcome measures were the resolution of neurosensory detachment, improvement in
visual symptoms and visual acuity, and resolution of leakage in FA. Secondary outcome and measures were the need
for re-injection and the adverse effects. The mean number of injections was 2 [range 1-3 injections] 6-8 weeks intervals
and follow up for 6 months [range 5-7 months]. All finding at baseline and each follow up visit were reported and
compared. The mean age of all patients was 40.3 years +/- 6.5 [range 25-50 years], 15 males and five females
patients. In acute CSC group, the mean baseline BCVA was 20/60 [log MAR 0.48] and improved to 20/30 [log MAR
0.18] with statistically significance difference change [P<0.003] and in [chronic and recurrent group], the mean baseline
VA was 20/80 [log MAR 0.60] and improved to 20/40 [log MAR 0.30] with statistically significance difference change
[P<0.002]. The mean baseline CRT for all patients was 486 +/- 86 micro m [range, 386-580], decreased to 316 +/- 56
micro m [range, 276-368] after 1 months with statistically significance difference change [P<0.02] and to 272 +/- 52
micro m [range 220-338] at last follow up with statistically significance difference change from the baseline [P<0.001].
Intravitreal Avastin [IVA] injection was associated with visual improvement and reduced neurosensory detachment
without adverse events in patients with CSC. Although these results are promising, further randomized controlled
studies would be helpful to understand this therapy for patients with CSC.
Cholestasis
etiology
Protective effect of Jasonia montana against ethinylestradiol-induced cholestasis in rats.
Hussein, Mohammed A.; Abdel Gawad, Soad M.
E-mail:[email protected]
October 6th University - Faculty of Pharmacy - Department of Biochemistry
SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 27-33 (65 ref.)
Keywords: Cholestasis-prevention and control; Cholestasis, Intrahepatic; Estrogens-therapeutic use; Ethinyl
Estradiol-therapeutic use; Rats; Plants, Medicinal
Abstract: Estrogens, and particularly glucuronides such as ethinylestradiol [EE], have been shown to cause
cholestasis in animal studies, by reducing bile acid uptake by hepatocytes. The aim of the present article is to
investigate anticholestatic activity of the ethanolic extract of the aerial parts of Jasonia montana against liver
cholestasis induced by EE in adult female rats in an attempt to understand its mechanism of action, which may pave
the way for possible therapeutic applications. Subcutaneous administration of 100 micro g/kg b.w. ethinylestradiol to
rats induced hepatocellular cholestasis with a significant decrease in serum cholesterol, bile acids and bilirubin levels
as well as in hepatic superoxide dismutase [SOD], glutathione peroxidase [GPx], glutathione reductase [GR] activities
and hepatic total, protein-bound and non-protein sulfhydryl groups. Also, treatment with EE produced significant
increase in serum Pi-glutathione-s-transferase [Pi-GST], gamma glutamyl transpeptidase [gamma-GT] and alphaglutathione-s-transferase [alpha-GST] activities as well as serum nitric oxide [NO] and tumor necrosis factor alpha
[TNF-alpha] level and hepatic malondialdehyde [MDA] level as compare to control group. Oral administration of the
aerial parts of ethanolic extract at a concentration of 150 mg/kg b.w. daily to rats treated with EE for 15 days showed a
significant protection against-induced decrease in serum cholesterol, bile acids and bilirubin levels. The treatment also
resulted in a significant increase in hepatic SOD, GPx and GR activities as well as hepatic total, protein-bound and
non-protein sulfhydryl groups. In addition, the extract could inhibit serum Pi-GST, gamma-GT and alpha-GST activities
as well as reduce serum TNF-alpha, NO and hepatic MDA as compare to ethinylestradiol treated rats. High content of
flavonoids and phenolic compounds was found in ethanolic extract, which may be responsible for free radical activity.
The results clearly suggest that the aerial parts of J, montana extract may effectively normalize the impaired
antioxidant status in ethinylestradiol [EE]-cholestatic model. Thus the extract may have a therapeutic value in druginduced biliary cholestasis as well as in hormonal therapy.
Classical Lissencephalies and Subcortical
A ten year-old girl with band heterotopia or double cortex [two brains].
Koul, Roshan; Alfutaisi, Amna; Alazri, Faisal; Jain, Rajeev
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Child Health
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 136-137
Keywords: Band Heterotopias-diagnosis; Magnetic Resonance Imaging; Seizures-etiology; Seizures-diagnosis
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Communication
Communication skills of doctors in a paediatric department, their perceptions and practices.
Ejaz, Muzamil Shabana; Ahmed, Aneela; Ali, S.M. Inkisar
E-mail:[email protected]
Dow University of Health Sciences - Civil Hospital and Lyari General Hospital - Department of Paediatrics
Pakistan Journal of Medical Sciences 2010; 26 (2): 384-389 (17 ref.)
Keywords: Clinical Competence; Physicians; Pediatrics; Professional Practice; Mothers; Perception; CrossSectional Studies
Abstract: To determine the perceptions and practices regarding communication skills of doctors in a paediatric
department of a tertiary care hospital. This was a cross-sectional study conducted in the Department of Paediatrics,
Dow Medical College and Civil Hospital Karachi from October to December 2008. Fifty four doctors including faculty,
consultants, registrars, postgraduates and medical officers of indoor and outdoor departments and wards were
enquired regarding their behavior and communication with parents and physicians. Their responses were recorded on
a questionnaire based on standards IMNCI/WHO guidelines for good communication skills. The data was later
analyzed and given as frequencies and percentages. Sixty five percent doctors were spending less than 10 minutes
with patients, seventy percent of the doctors claimed that they were polite and friendly with their patients, thirty seven
percent were using simple language, thirty nine percent were listening carefully without interruption whereas eighty
percent did not know the appropriate time of follow up. Seventy four percent doctors claimed that lack of parental
understanding is one of the important reasons for lack of effective communication. Other reasons reported were large
number of patients [56%] lack of adequate time [50%], inadequate numbers of doctors [35%] and other paramedical
staff [30%]. Majority of doctors of Paediatric Department are using inadequate communication skills. Large number of
patients, lack of adequate number of doctors and paramedical staff and lack of parental understandings were the
reasons given by the doctors for inadequate communication practices.
Congenital Abnormalities
epidemiology
Incidence and determinants of birth defects and enzyme deficiencies among live births in Oman:
a review of the 2005 national register.
Khandekar, Rajiv; Jaffer, Yasmin
E-mail:[email protected]
Ministry of Health - Department of Non-communicable Diseases Control
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 23-30 (37 ref.)
Keywords: Congenital Abnormalities-etiology; Incidence; Risk Factors; Consanguinity
Abstract: In 2003, the Omani Ministry of Health Child Health Care Program initiated a national Birth Defects [BD]
Register. This paper reviews the magnitude and risk factors of birth defects in children born and registered in 2005
using data from the BD Register. Pediatricians and neonatologists examined children with BDs found either during
screening at birth or when attending clinics in their first year of their life. Clinical examination, laboratory, sonographic
and radiological investigations were carried out. A pre-tested form was used to note personal details, type of birth
defect including International Classification of Diseases-10 [ICD-10] codes of BD and selected risk factors. The
incidence rates per 100 live births were calculated. The annual incidence of BD in Oman was 2.53% [95% CI
2.382.68]. Males had a significantly higher risk of BD than females [relative risk [RR]=2.0]. The regional variation of BD
was also significant [X [2]=363]. The incidence of anaemia due to enzyme disorders was 1.4%. BD of urogenital
organs, hands and feet and Down's syndrome were the main types of anatomical defects. Consanguinity among
parents [RR=0.85] and low birth weight [RR=0.28] was negatively associated to birth defects. Mothers giving birth at
gestational age of<37 weeks [RR=1.89] had a higher risk of having children with BD. Maternal and paternal age were
not associated to BD. The national Register for BD is an important evaluation tool. Both genetic and acquired risk
factors seem to affect BD rates and types in Oman.
Contraception
Non-enzymatic antioxidant status of women using four different methods of contraception.
Akinloye, O.; Oyabiyi, S.A.; Oguntibeju, O.O.; Arowojolu, A.O.
Ladoke Akintola University of Technology - College of Health Sciences - Department of Chemical Pathology
Pakistan Journal of Medical Sciences 2010; 26 (2): 374-379 (18 ref.)
Keywords: Antioxidants; Tocopherols-blood; Ascorbic Acid-blood; Selenium-blood; Cross-Sectional Studies;
Women; Body Mass Index
Abstract: To investigate antioxidant status of women on four different methods of contraception. Sixty non-pregnant
women aged 16-45 years on oral contraceptive pills, injectables, Norplant and intra-uterine contraceptive devices [IUD]
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Subject Index
attending the Family Planning Clinics of the University College Hospital [UCH] and Adeoyo Maternity Hospital, Ibadan
were recruited for the study. Fifty-eight apparently healthy women aged 16-45 years who were not on any
contraceptive served as a control group. The body mass index [BMI] of all participants [subjects and controls] was
determined following standard protocol. Serum levels of ascorbic acid, tocopherol, malondialdehyde, bilirubin,
creatinine, uric acid, total protein and albumin were determined using standard spectrophotometric methods.
Progesterone was estimated by the chemilumiscence method while selenium was determined by atomic absorption
spectrophotometry [AAS]. The BMI was significant in women on oral contraceptive pills [OCP] when compared to the
control group [P<0.05] but insignificant [P>0.05] in intra-uterine device [IUD], injectables and Norplant users. The mean
serum ascorbic acid [P<0.01], tocopherol [P<0.05], total protein [P<0.01], albumin [P<0.05], uric acid [P<0.05],
selenium [P<0.01] of women on OCP were significantly lower when compared to the control group but insignificant
[P>0.05] in users of other contraceptive methods. Serum levels of malondialdehyde was significantly elevated in
women on OCP [P<0.01] than in control group and insignificant P>0.05] in users of other contraceptive methods. There
was no significant association between progesterone and antioxidants in women on OCP, IUD, injectables and
Norplant. Oral contraceptive pills showed a significant decreasing effect on the antioxidant status of its users while
IUD, injectables and Norplant did not indicate any significant effect. Routine monitoring of the antioxidant status of
women on different methods of contraceptive particularly those on OCP is recommended.
Coronary Angiography
methods
The higher cross-over rate from transradial to transfemoral coronary angiography: do we have
the explanation?
Sallam, Mansour; Al Hadi, Hafidh
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Medicine and Health Sciences
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 269-271 (4 ref.)
Keywords: Radial Artery; Femoral Artery
Coronary Artery Bypass
psychology
The effect of education on the stress levels in patients undergoing coronary artery bypass graft
surgery.
Ozer, Nadiye; Akyil, Rahsan; Yurttas, Afife
Ataturk University - Health Sciences Faculty
Pakistan Journal of Medical Sciences 2010; 26 (2): 282-287 (18 ref.)
Keywords: Educational Status; Stress, Psychological
Abstract: To investigate the effect of education on the stress levels associated with Coronary Artery Bypass Graft
[CABG] surgery in the week after CABG surgery. The study used a quasi-experimental design. Patients were selected
through convenience sampling at a university hospital in Turkey. There were 60 patients in the study; 30 in the
experimental group and another 30 in the control group. Data were collected using the Stressors Scale associated with
CABG on the third day of the post-operative period. Cronbach's alpha of the scale was 0.89. Alpha coefficients ranged
from 0.82 to 0.79.The difference between the score averages of the experimental and control group was p=0.002 for
the illness-related subscale, p=0.031 for the hospital related subscale, and p=0.006 in total. Education was effective for
reduction of stress associated with CABG surgery.
Coronary Artery Disease
Spontaneous coronary artery dissection associated with apical hypertrophic cardiomyopathy.
Tuncer, Mustafa; Gumrukcuoglu, Hasan Ali; Ekim, Hasan; Gunes, Yilmaz; Simsek, Hakki
E-mail:[email protected]
Yuzuncu Yil University - Faculty of Medicine - Department of Cardiology
Pakistan Journal of Medical Sciences 2010; 26 (2): 474-477 (10 ref.)
Keywords: Coronary Vessels-pathology; Cardiomopathy, Hypertrophic; Electrocardiography; Coronary Artery
Bypass
Abstract: Apical hypertrophic cardiomyopathy [HCM] is a relatively uncommon inherited disease. Spontaneous
coronary artery dissection [SCAD] is also uncommonly observed, which often occurs in pregnant or post partum
20
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Subject Index
women but is rare in men. This report describes a 38 years old man with apical hypertrophic cardiomyopathy who
developed SCAD leading to acute inferior myocardial infarction. After emergent appendectomy operation at another
hospital, he was immediately transferred to the Cardiology Department of our hospital due to acute myocardial
infarction. He emergently underwent coronary angiography which showed a long dissection involving the right
coronary. He underwent an emergent CABG with cardiopulmonary bypass. Postoperative recovery was uneventful and
he was discharged. According to our knowledge, no case of spontaneous coronary artery dissection associated with
apical hypertrophic cardiomyopathy unrelated to postpartum period or oral contraceptive use has been reported so far.
Cyclooxygenase 2 Inhibitors
administration and dosage
Preparation and evaluation of celecoxib transdermal patches.
Jayaprakash, S.; Halith, S. Mohamed; Firthouse, P.U. Mohamed; Yasmin; Nagarajan, M.
E-mail:[email protected]
KM College of Pharmacy - Department of Pharmaceutics
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 279-283 (20 ref.)
Keywords: Administration, Cutaneous; Pyrazsles-administration and dosage; Rabbits; Rats; Solubility;
Sulfonamides-administration and dosage
Abstract: Celecoxib Transdermal patches were prepared by using different polymers such as hydroxylpropylmethylcellulose [HPMC], methylcellulose [MC], Polyvinylpyrolidone [PVP] .The in-vitro release of the drug from
the formulations were studied using commercial semi permeable membrane. The prepared formulation were subjected
to various physicochemical evaluation test, in-vitro dissolution studies, kinetics studies shows diffusion might be one of
the prominent mechanism influencing the drug release. To confirm the fact Peppas plot was drawn, which confirmed
that the diffusion mechanism involved in the drug release was of non fickian diffusion type. ex-vivo diffusion studies by
using rat skin, guinea pig skin and pig ear skin and finally in-vivo evaluation studies [the patch F4 HPMC 0.75%, PVP
0.25%] were carried out by using rabbits.
Delivery of Health Care
Four decades of progress: evolution of the health system in Oman.
Alshishtawy, Moeness M.
E-mail:[email protected]
Ministry of Health - General of Planning Department
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 12-22 (33 ref.)
Keywords: Delivery of Health Care, Integrated; Health Systems Plans; Health Policy
Abstract: Since 1970, Oman has witnessed rapid and significant improvements in health made possible largely
because of the country's success in building a state-of-the-art health care infrastructure. This paper presents Oman's
experience in health development, analyses the whole system, highlights its strengths and delineates the factors to
which Oman's success could be attributed. Furthermore, health care financing and expenditures, health care
workforce, the delivery system, quality and other issues are discussed in detail. The paper intends also to study
thoroughly the organisation of Oman's health system and discuss health policy, and planning in Oman. This analysis
could serve as a source of information for future investigation and development of the health system in Oman.
Dental Devices, Home Care
Comparison of plaque removal efficacy of new and 3-month-old toothbrushes in children.
Malekafzali, B.; Biria, M.; Tadayon, N.; Abbasi, H.
Shahid Beheshti University of Medical Sciences - Faculty of Dentistry - Department of Paediatric Dentistry
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 115-120 (22 ref.)
Keywords: Toothbrushing; Dental Plaque; Dental Plaque Index
Abstract: The cost of replacing toothbrushes at frequent intervals may be prohibitive in underdeveloped countries.
The objective of this study in Tehran was to compare the plaque removal efficacy of new and 3-month-old
toothbrushes in children. In a randomized, crossover study, 93 children aged 7-9 years old received a new manual
toothbrush to use twice per day for 3 months. Plaque scores were measured using the modified Quigley-Hein plaque
index after children had brushed for 60 seconds with either a new or their used toothbrush. Bristle wear of worn
brushes was assessed by measuring brushing surface areas on digital images. Compared with new brushes in the
same subjects, no statistically significant differences were found for plaque score reductions for 3-month-old
toothbrushes exhibiting various degrees of wear. Worn toothbrushes are equally effective as new ones for children.
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Subject Index
Dermatomycoses
epidemiology
The prevalence of superficial fungal infections in the elderly.
Zarrin, Majid; Arab, Seyedeh Elham; Yaghoobi, Reza
E-mail:[email protected]
Ahvaz Jundishapur University of Medical Sciences - Medical School - Department of Parasitology and Mycology
Pakistan Journal of Medical Sciences 2010; 26 (2): 364-367 (20 ref.)
Keywords: Prevalence; Age Distribution; Sex Distribution
Abstract: The main goals of this study were to determine the distribution and frequency of dermatologic diseases in
geriatric patients according to age and gender, and the place of residence. A total of 349 patients aged 65 years and
over lived in elderly care centers and geriatric patients in Ahvaz Jundishapur University Hospitals were studied in
winter of 2008. Specimens were collected from clinically suspected fungal infections of various body sites including
toenail, fingernail, body and groin, head and scalp, face, hand, and foot. The distribution of the patients in the different
age groups was as follows: 16 patients in the 65-74 year age group [11 female [69%] and 5 male [31%]]; 11 patients in
the 75-84 year age group [7 female [58%] and 5 male [42%]]; and 3 patients in the>85 year age group [1 female [33%]
and 2 male [67%]]. Overall, the 3 most frequent diseases in this cohort of patients were erythrasma [16 patients
[53.3%]], onychomycosis [10 patients [33.3%]] and skin yeast infections [4 patients [13.4%]]. In this study
Corynebacterium minutissimum was the most frequent agent of infections [53.3%] followed by filamentous fungi
[23.3%], C. albicans, Candida sp. and yeasts [6.7% each]. Only one dermatophyte [T. verrucosum] was isolated [3.3%]
Diabetes Mellitus
prevention and control
Controlling diabetes mellitus: struggle continued.
Shaikh, M. Zaman
E-mail:[email protected]
Dow University of Health Sciences
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 223-224 (8 ref.)
Keywords: Diabetes Mellitus-history; Diabetes Mellitus-economics; Diabetes Complications-prevention and control;
Blood Glucose; Life Style
Diabetes Mellitus, Type 2
genetics
Clinically-defined maturity onset diabetes of the young in Omanis: absence of the Common
caucasian gene mutations.
Woodhouse, Nicholas J.Y.; Elshafie, Omayma T.; Al Mamari, Ali S.; Mohammed, Nagi H.S.; Al Riyami, Fatma;
Raeburn, Sandy
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 80-83 (21 ref.)
Keywords: Mutation-genetics; Family; Glucokinase
Abstract: We are seeing a progressive increase in the number of young patients with clinically defined maturity onset
diabetes of the young [MODY] having a family history suggestive of a monogenic cause of their disease and no
evidence of autoimmune type 1 diabetes mellitus [T1DM] . The aim of this study was to determine whether or not
mutations in the 3 commonest forms of MODY, hepatic nuclear factor 4alpha [HNF4 alpha], HNF1alpha and
glucokinase [GK], are a cause of diabetes in young Omanis. The study was performed at Sultan Qaboos University
Hospital [SQUH], Oman. Twenty young diabetics with a family history suggestive of monogenic inheritance were
identified in less than 18 months; the median age of onset of diabetes was 25 years and the median body mass index
[BMI] 29 at presentation. Screening for the presence of autoimmune antibodies against pancreatic beta cells islet cell
antibody [ICA] and glutamic acid decarboxylase [GAD] was negative. Fourteen of them consented to genetic screening
and their blood was sent to Prof. A. Hattersley's Unit at the Peninsular Medical School, Exeter, UK. There, their DNA
was screened for known mutations by sequencing exon 1-10 of the GCK and exon 2-10 of the HNF1alpha and
HNF4alpha genes, the three commonest forms of MODY in Europe. Surprisingly, none of the patients had any of the
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Subject Index
tested MODY mutations. In this small sample of patients with clinically defined MODY, mutations of the three most
commonly affected genes occurring in Caucasians were not observed. Either these patients have novel MODY
mutations or have inherited a high proportion of the type 2 diabetes mellitus [T2DM] susceptibility genes compounded
by excessive insulin resistance due to obesity.
Diet
Diet, nutritional status and school performance t among adolescents in Gaza Strip.
Abudayya, A.; Shi, Z.; Abed, Y.; Holmboe Ottesen, G.
E-mail:[email protected]
University of Oslo - Institute of Health and Society - Department of Community Medicine
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 218-225 (28 ref.)
Keywords: Nutritional Status; Educational Measurement; Schools; Questionnaires; Cross-Sectional Studies;
Anthropometry
Abstract: The associations between dietary intake, nutritional status and school performance among 932
adolescents aged 12-15 years were examined in a cross-sectional survey in 2002 in north Gaza Strip. School
performance was obtained from school records and height and weight were measured for body mass index [BMI]. Selfadministered questionnaires included sociodemographic characteristics and food frequency intakes. Adolescents
consuming fruit and vegetables more than 3 times per week were more likely to have good school performance [72.6%
versus 59.9%]. When adjusting for sociodemographic variables and BMI, fruit and vegetables intake was positively
associated with school performance [OR = 1.61, 95% Cl: 1.11-2.32] and stunting was negatively associated [OR =
0.53, 95% Cl: 0.31-0.90]. The findings support a broader implementation of school nutrition programmes.
Disease Management
Integrated Management of Childhood Illness in Lahej, Yemen: a qualitative analysis from the
perspective of health providers.
Basaleem, H.O.; Amin, R.M.
E-mail:[email protected]
University of Aden - Faculty of Medicine and Health Sciences - Department of Community Medicine and Public Health
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 101-108 (23 ref.)
Keywords: Health Personnel; Perception; Interviews as Topic
Abstract: Health providers' perceptions about the Integrated Management of Childhood Illness [IMCI] in Lahej
governorate, Yemen, were explored in a qualitative analysis of 12 in-depth interviews in 2007. The following themes
emerged: appreciation of clinical aspects of IMCI but unclear about community IMCI; IMCI working better in peripheral
than central health facilities; inflexible rules; lack of integration of services; poor supervision; multiple roles for one
person; success of immunization; basic equipment and drug supplies deficient; conflicting views about health
committees and community participation; and solutions for community health problems. After 4 years of IMCI
experience in Yemen, the gaps identified would endanger the positive influence of IMCI unless action is undertaken at
different levels.
Drug Prescriptions
Effectiveness of three interventions on primary care physicians' medication prescribing in
Riyadh city, Saudi Arabia.
Qureshi, N.A.; Neyaz, Y.; Khoja, T.; Magzoub, M.A.; Haycox, A.; Walley, T.
Ministry of Health - General Administration for Mental Health and Social Services and Medical Research
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 172-179 (33 ref.)
Keywords: Physician's Practice Patterns; Primary Health Care; Physicians, Primary Care; Teaching; Quality
Indicators, Health Care; Cost-Benefit Analysis
Abstract: A number of strategies have been shown to improve the quality of drug prescriptions. The objective of this
study was to implement and assess the effectiveness of 3 interventions on physicians' prescribing and cost
containment: training physicians about quality prescribing, regulatory and administrative measures to improve rational
drug prescribing; and a multi-faceted approach using 2 these strategies plus additional elements. Three public health
centres, 1 for each intervention, were randomly selected, 61 physicians were trained in drug prescribing and completed
a pre- and post-training questionnaire, and 100 post-intervention prescriptions from each centre were compared. All 3
interventions effectively improved the quality of drug prescriptions and the notation of drug-related information and
trainees returned positive evaluations of the training course. Whether or not physicians' improvement in prescribing will
be sustained is unclear and therefore subsequent follow-up evaluations are needed.
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Subject Index
Medication prescribing pattern in primary care in Riyadh city, Saudi Arabia.
Neyaz, Y.; Khoja, T.; Qureshi, N.A.; Magzoub, M.A.; Hoycox, A.; Walley, T.
Ministry of Health - General Directorate for Quality Development
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 149-155 (34 ref.)
Keywords: Physician's Practice Patterns; Primary Health Care; Physicians, Primary Care; Cross-Sectional Studies
Abstract: Physicians' prescribing behaviour is closely linked with patient safety and this area is poorly researched in
Saudi Arabia. The objective of this stulf was to analyse physicians' prescribing patterns and the adequacy of noted
information in the primary health care sector in Riyadh city. All medication prescriptions from 5 public [n = 1182] and 5
private [n - 1200] health centres were collected by simple random sampling during 1 working day. Antibiotics were the
most commonly prescribed drugs in both sectors. The mean number of drugs per prescription was 2.08 and 2.36 in the
public and private sectors respectively. Information and instructions noted on prescriptions varied considerably
between private and public health centres. Similarly the medication prescribing pattern differed across the 2 health
settings. Primary care physicians in Saudi Arabia need continuing training to improve their prescribing practices.
Physicians' medication prescribing in primary care in Riyadh city, Saudi Arabia. Literature
review, part1: variations in drug prescribing.
Neyaz, Y.; Qureshi, N.A.; Khoja, T.; Magzoub, M.A.; Haycox, A.; Walley, T.
Ministry of Health - General Directorate for Quality Development
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 126-131 (61 ref.)
Keywords: Physician's Practice Patterns; Medication Errors; Primary Health Care; Physicians, Primary Care;
Teaching
Abstract: Rational prescribing is associated with improved safety in drug use, better quality of life for patients and
cost-effective care. Medication prescribing is a relatively unexplored area of research in Saudi Arabia and until now
most studies have been in the secondary and tertiary health care system. This paper is the first of 3 review articles that
form the background for a series of 5 interconnected studies of prescribing patterns and medication errors in the public
and private primary health care sectors of Saudi Arabia. A MEDLINE search was conducted to identify papers
published in peer-reviewed journals over the previous 3 decades. The paper reviews variations in prescribing patterns
and influences on physicians' prescribing behaviour worldwide and in Saudi Arabia.
Physicians' medication prescribing in primary care in Riyadh city, Saudi Arabia. Literature
review, part 2: rational prescribing.
Khoja, T.; Qureshi, N.A.; Neyaz, Y.; Magzoub, M.A.; Haycox, A.; Walley, T
Cooperation Council for the Arab States of the Gulf
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 132-139 (71 ref.)
Keywords: Physician's Practice Patterns; Primary Health Care; Physicians, Primary Care; Quality of Health Care;
Medication Errors
Abstract: Unlike suB-optimal prescribing rational prescribing, coupled with certain indicators, is associated with
improved safety in drug use in drug for prescribing, better quality of life for patients and cost-effective care. Medication
prescribing is relatively unexplored area of research in Saudi Arabia and until now most studies have been health care
system. This paper is the second of 3 review articles that form the interconnected studies of prescribing patterns and
medication errors in the public care sectors of Saudi Arabia. A MEDLINE search was conducted to identify papers
published in peer- reviewed journals over the previous 3 decades. The paper reviews rational prescribing with its
indicators suboptimal prescribing, classification of medication errors, and how to achieve quality in health care
prescribing worldwide and in Saudi Arabia.
Physicians' medication prescribing in primary care in Riyadh city, Saudi Arabia. Literature
review, part 3: prescribing errors.
Qureshi, N.A.; Neyaz, Y.; Khoja, T.; Magzoub, M.A.; Haycox, A.; Walley, T.
E-mail:[email protected]
Ministry of Health - General Administration for Mental Health and Social Services and Medical Research
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 140-148 (100 ref.)
Keywords: Medication Errors; Physician's Practice Patterns; Primary Health Care; Physicians, Primary Care
Abstract: Medication errors are globally huge in magnitude and associated with high morbidity and mortality together
with high costs and legal problems. Medication errors are caused by multiple factors related to health providers,
consumers and health system, but most prescribing errors are preventable. This paper is the third of 3 review articles
that form the background for a series of 5 interconnected studies of prescribing patterns and medication errors in the
public and private primary health care sectors of Saudi Arabia. A MEDLINE search was conducted to identify papers
published in peer-reviewed journals over the previous 3 decades. The paper reviews the etiology, prevention
strategies, reporting mechanisms and the myriad consequences of medication errors.
Predictors of quality of medication prescribing in primary care in Riyadh city, Saudi Arabia.
Neyaz, Y.; Khoja, T.; Quresh, N.A.; Magzoub, M.A.; Haycox, A.; Walley, T.
Ministry of Health - General Directorate for Quality Development
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 167-171 (22 ref.)
Keywords: Physician's Practice Patterns; Primary Health Care; Physicians, Primary Care; Quality Indicators, Health
Care; Questionnaires; Cross-Sectional Studies
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Subject Index
Abstract: Identifying the indicators of good quality medication prescribing assists physicians in preventing medication
errors. This study in Riyadh city aimed to examine the relationship between physicians' self-reported influences on
prescribing and the quality of their prescribing, defined as the completeness and accuracy of their prescription
documentation. A sample of 600 randomly selected prescriptions written by 87 physicians were rated as high or low
quality. The same physicians completed a questionnaire to determine the indicators of quality prescribing. The 7
components identified with factor loadings +0.5 or -0.5 were subjected to binary logistic regression modelling. While a
range of potential quality indicators of drug prescribing were identified, none of the variables underpinning the 7
components/factors survived the binary logistic regression mode. More studies are needed that take into account other
quality indicators of medication prescribing in Saudi Arabia.
Dysmenorrhea
epidemiology
A study of dysmenorrhea among female residents aged 18-45 years in semirural area of West
Turkey.
Unsal, Alaettin; Ayranci, Unal; Tozun, Mustafa
Eskisehir Osmangazi University - Medical Faculty - Public Health Department
Pakistan Journal of Medical Sciences 2010; 26 (2): 335-340 (23 ref.)
Keywords: Prevalence; Cross-Sectional Studies; Family; Medical History Taking; Depression-epidemiology;
Dysmenorrhea-etiology
Abstract: To determine the correlates and the prevalence of Dysmenorrhea in a group of women. This cross
sectional study was carried out on the 556 subjects aged 18-45 years in a town of western Turkey between January,
and March 2009. We used visual analogue scale to assess the severity of dysmenorrhea. The data were evaluated by
Logistic Regression Analysis and Chi-square tests. The prevalence of dysmenorrhea was 66.7%. About 32.3% of the
women described their dysmenorrhea as severe. When compared to the age group of 35 and over, the risk of
dysmenorrhea was 2.677 fold higher in the age group of 24 and over. The risk of dysmenorrhea was nearly 2.5 fold
higher in those who had family history of dysmenorrheal. The prevalence of depression among women was relatively
high. This indicates the need for knowledge concerning dysmenorrhea to be addressed by menstruation-related health
education programs.
Ear, Inner
surgery
Hearing improvement after partial labyrinthectomy: resection of petrous apex cholesterol
granuloma.
Hagr, Abdulrahman A.
E-mail:[email protected]
King Saud University - King Abdulaziz University Hospital - Department of Otolaryngology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 249-254 (15 ref.)
Keywords: Hearing; Granuloma, Foreign-Body-surgery; Cholesterol; Petrous Bone; Cranial Nerves
Abstract: We present the case of a 57 year-old male presenting with symptomatic petrous apex cholesterol
granuloma, multiple cranial nerve weaknesses and deafness of the left ear. The chosen intervention was a cholesterol
granuloma resection via the translabyrinthine approach. This resulted in cranial nerve recovery and improved facial
functionality. Hearing in the operated ear improved within 3 months after surgery. The patient experienced no
postoperative complications. We conclude that a translabyrinthine approach can be used for drainage of petrous apex
cholesterol granulomas with a chance of hearing loss recovery.
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Echinococcosis, Hepatic
complications
Predictive clinical factors, diagnosis, and management of intrabiliary rupture of a hepatic
hydatid cyst in Erbil Teaching Hospitals, Erbil province-North Iraq.
Zangana, Abdulqadir Maghded; Aldabbagh, Ali Abdulrazak; Younis, Saeed Nahdem
E-mail:[email protected]
Hawler Medical University - College of Medicine - Department of General Surgery and Gastroenterology
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 22-31 (20 ref.)
Keywords: Rupture-diagnosis; Rupture-surgery; Echinococcosis, Hepatic-surgery; Prospective Studies; Early
Diagnosis
Abstract: This study investigates the clinical factors associated with an intrabiliary rupture of a hepatic hydatid cyst
for early diagnosis and management of cystobiliary communications in patients with liver echinococcosis and presents
our experience with this condition. A prospective study included patients with hepatic hydatid cysts treated between
years 2000 and 2007 in a single institution, Erbil Teaching hospital Erbil province-Iraq. Database containing 121
patients with a hepatic hydatid cyst were reviewed. The following variables were analyzed as potential predictors of an
intrabiliary rupture: age, sex, type, duration of symptoms, findings on physical examination, leukocyte count, liver
function test results, serologic test results, suggestive ultrasonographic findings, ltrasonographic cyst features [type,
diameter, number, and localization], and whether the cyst is primary or recurrent. Multivariate analysis showed that the
independent clinical factors for the presence of an occult rupture were a history of gastric upset in the form of nausea
and vomiting [p=0.004], alkaline phosphatase level greater than 140 U/L [p=0.004], total bilirubin level greater than 0.7
mg/dL [>13.5 micro mol/L] [p<0.001], and cyst diameter greater than 14.5 cm [p<0.001] in multivariate analysis.
Multivariate analysis also showed that history of jaundice [p<0.001], jaundice found on physical examination [p=0.05],
cyst diameter greater than 10.5 cm [p=0.009], a type IV cyst [p<0.001], and suggestive ultrasonographic findings
[p<0.001] were the independent clinical predictors for the presence of a frank intrabiliary rupture. Patients with
cystobiliary communications had increased morbidity rates to 47.8% of 23 patients vs. 9.9% of 98 patients [p<0.001],
and longer mean postoperative hospital stays [11.5 versus 8.4 days; p=0.03] compared with others. Clinical predictors
should be considered for early diagnosis and proper management of intrabiliary ruptures in patients with hepatic
hydatid cysts, since a frank intrabiliary rupture of hepatic hydatid cyst is a rare but serious event, and one should be
aware of it in differential diagnosis of obstructive jaundice. Patients with cystobiliary communications had increased
morbidity rates.
Education, Medical
Assessment of self-reported cardoimetabolic risk awareness among physicians.
Alfadhli, Eman; Hanafi, Manal Ibrahim; Sultan, Intessar
Alexandria University - Faculty of Medicine - Department of Community Medicine
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 677-684 (20 ref.)
Keywords: Physicians; Health Knowledge, Attitudes, Practice; Coronary Disease; Risk Factors; Life Style; Primary
Prevention; Questionnaires
Abstract: Lack of coronary artery disease [CAD] risk factors [RFs] knowledge and orientation among physicians
would indicate a defect in their attitude towards primary preventive strategies. To assess the prevalence and the
awareness of self-reported major and life-style CAD risk factors among physicians working in Medina, Saudi Arabia. A
cross-sectional survey was conducted from May 2008 to January 2009 to screen a stratified random sample of 209
physicians aged 41.8 +/- 9.1 years. Using a p re-coded questionnaire, the prevalence and awareness of CAD major
and life-style RFs were self-reported by the participants. Life-style RFs were more prevalent than major RFs among
physicians [86% Vs 48.8%], 41.2% of the physicians were having combined RFs increasing their future risk of CAD.
Female physicians lost their gender protection despite being significantly younger than males [39.9 +/- 8.1 Vs 42.6 +/9.4 years, p < 0.00], however they had longer duration of diabetes [6.7 +/- 6.4 vs 5.6 +/- 4.3 years, p < 0.000] and
hypertension [8.5 +/- 6.8 Vs 7.98 +/- 7] years, p < 0.00]. Less than 10% of physicians were unaware of their serum
lipids with no gender difference. Physicians were likely to be aware of their serum lipids if they had hypertension [p =
0.3] or family history of diabetes [p = 0.04]. While physicians who were unaware of their serum lipids tend to consume
more dairy products [P = 0.02]. Life-style RFs are prevalent among physicians working in Medina together with
substantial unawareness of their lipid profile this indicates a need for increasing their awareness about lipid screening
programs and initiating healthy lifestyle modifications as essential primary preventive strategies to minimize their future
risk of CAD.
Privatisation of medical education: viewpoints with a global perspective.
Shehnaz, Syed I.
E-mail:[email protected]
Gulf Medical University - Department of Pharmacology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 6-11 (47 ref.)
Keywords: Privatization; Students, Medical
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Re: evaluation tools in postgraduate medical education-do we need "made in oman" tools?
Al Wardy, Nadia
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Medical Education Unit
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 280-281 (2 ref.)
Keywords: Educational Measurement
Education, Medical, Undergraduate
Assessment methods in undergraduate medical education.
Al Wardy, Nadia M.
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Medical Education Unit
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 203-209 (51 ref.)
Keywords: Educational Measurement-methods; Knowledge
Abstract: Various assessment methods are available to assess clinical competence according to the model
proposed by Miller. The choice of assessment method will depend on the purpose of its use: whether it is for
summative purposes [promotion and certification], formative purposes [diagnosis, feedback and improvement] or both.
Different characteristics of assessment tools are identified: validity, reliability, educational impact, feasibility and cost.
Whatever the purpose, one assessment method will not assess all domains of competency, as each has its
advantages and disadvantages; therefore a variety of assessment methods is required so that the shortcomings of one
can be overcome by the advantages of another.
Entamoeha histolytica
isolation and purification
Prevalence of entamoeba histolytica in humans.
Tasawar, Zahida; Kausar, Shabana; Lashari, M.H.
Bahauddin Zakariya University - Institute of Pure and Applied Biology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 344-348 (57 ref.)
Keywords: Feces-parasitology; Prevalence; Age Factors; Sex Characteristics
Abstract: The present survey was carried out to determine the prevalence of human amebiasis. During the study,
1360 fecal samples were examined from February 2007 to December 2007 at Nishtar Hospital, Multan. Out of 1360
hosts examined, 295 were infected with E. histolytica. The overall prevalence of E. histolytica was [21.69%].
Relationship between sex and E. histolytica in humans showed that the infection of E. histolytica was more prevalent in
male hosts [22.36%] as compared to female hosts [20.9%]. However the difference was statistically non-significant [P>
0.05]. Results regarding the relationship between age and E. histolytica revealed that the parasite had highest
prevalence [30.82%] in age group of 1 day to 15 years and lowest prevalence [17.34%] in age group of 31 to 45 years.
The difference was statistically significant [P<0.05] .
Epilepsy
surgery
[Brain tumors and epilepsy : postoperative evaluation of surgical procedures].
Ghostine, B.; Ali, Y.; Menassa, L.; Okais, N.; Nohra, G.; Rizk, T.; Maarawi, J.; Samaha, E.; Moussa, R.
University of Saint-Joseph - Department of Radiology
LMJ - Lebanese Medical Journal 2010; 58 (2): 71-75 (14 ref.)
Keywords: Brain Neoplasms-surgery; Brain Neoplasms-pathology; Prognosis; Treatment Outcome; Magnetic
Resonance Imaging
Abstract: To study the efficacy of surgery on the postoperative control of epilepsy in patients operated for brain
tumors. Forty patients operated for supratentoriel cerebral tumors with epilepsy, at Hotel-Dieu de France [HDF]
hospital center, between 1983 and 2005, were included in this study. Clinical, paraclinical and surgical information
were collected. The extent of the tumor resection was based on the postoperative MRI results. The mean duration of
the follow-up was 52 +/- 6 months [from 6 months to 10 years]. 62.5% of our patients have had acute seizures [<1
year] and 37% had experienced chronic seizures [>/=1 year]. The histopathologic exam revealed 2 DNET, 3 pilocytic
astrocytomas, 2 diffuse astrocytomas, 6 A oligodendrogliomas, 7 B oligodendrogliomas, 7 anaplastic astrocytomas and
27
IMEMR Current Contents
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glioblastomas and 13 meningiomas. Twenty-two patients had a complete resection, whereas the postoperative MRI of
18 patients have shown a tumoral remnant. After one year of follow-up, a complete remission was noted in 57,5% of
the patients [EngelI]. The prognostic factors of good outcome were : low-grade glial tumors [I +/- II] , meningiomas, and
complete tumor resection. The efficacy of surgery for epilepsy associated to cerebral tumors, established by the
majority of articles, matched the results obtained for the patients operated at HDF, with complete seizures control in
57,5% of patients. This control depended essentially on the extent of tumor resection and on tumor's nature.
Erythrocyte Indices
Role of mean corpuscular volume as screening test for thalassaemia in pregnant women at Isra
University Hospital Hyderabad.
Amna, A.; Zehra, N.; Haider, G.; Anjum, F.; Rani, S.; Munir, A.A.
E-mail:[email protected]
Isra University Hospital - Department of Obstetrics and Gynecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 390-393 (14 ref.)
Keywords: beta-Thalassemia-diagnosis; Prenatal Diagnosis; Sensitivity and Specificity; Predictive Value of Tests
Abstract: To see the sensitivity, specificity, positive and negative predictive value of mean corpuscular volume [MCV]
in screening for beta thalassemia minor in pregnant women attending antenatal clinic at Isra University Hospital [IUH]
Hyderabad. This validation study was conducted at the department of obstetrics and gynecology Isra University
Hospital Hyderabad from 1st November 2004 to 30th October 2005. Women were interviewed using a pre designed
questionnaire regarding their demographic profiles and Gestational age at the time of presentation. On their first
antenatal visit MCV were checked as less than or equal to 70 fl on complete blood picture. HbA2 level were assessed
by Hemoglobin electrophoresis to find out the carrier of beta thalassaemia minor. The data was analyzed on SPSS vr
15. This study showed that MCV is a good screening test for beta thalassemia minor. Out of 100 screened subjects
53% had MCV less than 70 fl or equal to 70 fl. Positive MCV test [<70 fl] showed a sensitivity of 79% and specificity of
30% in screening for beta thalassaemia trait. The positive and negative predictive values were 56% respectively. Our
study showed that MCV is 79.9% sensitive and 30% specific and positive and negative predictive value is 56% in
detection of beta thalassaemia minor. It was found to be a good screening tool in pregnant women for beta
thalassaemia. This test can be adopted in future as part of evaluation for sub fertility in all young women.
Esophageal Fistula
radiography
Aortoesophageal fistula caused by a foreign body.
Al Saqri, Badriya; Kamona, Atheel; Al Lamki, Neela
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Radiology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 266-268 (6 ref.)
Keywords: Aorta-pathology; Radiography, Thoracic; Foreign Bodies; Aneurysm, False; Tomography, X-Ray
Computed
Esophageal Neoplasms
epidemiology
Esophageal cancer in Iran: a review.
Sadjadi, Alireza; Marjani, Hajiamin; Semnani, Shahryar; Moghaddanr, Siavosh Nasseri
Tehran University of Medical Sciences - Shariati Hospital - Digestive Disease Research Center
MEJC - Middle East Journal of Cancer 2010; 1 (1): 5-14 (72 ref.)
Keywords: Carcinoma, Squamous Cell-epidemiology; Incidence; Risk Factors; Adenocarcinoma-epidemiology;
Esophageal Neoplasms-etiology; Esophageal Neoplasms-pathology; Esophageal Neoplasms-prevention and control
Abstract: Esophageal cancer is the second and third most common malignancy in Iranian males and females,
respectively, claiming lives of approximately 5800 Iranians each year. Squamous cell carcinoma [SCC] is presently the
most common type accounting for about 90% of all esophageal cancers in Iran. Recent studies have shown that there
is a gradual increase in the incidence of adenocarcinoma of the distal esophagus along with gastric cardia
adenocarcinoma. Thirty-five years ago, the age standardizied rate [ASR] of esophageal SCC in the city of Gonbad
[Golestan Province, northeast of Iran] was found to be one of the highest rates for any single cancer that had been
reported worldwide [ASR >100/10[5]/year]. Recent studies have shown that the incidence of SCC in Gonbad has
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declined to less than half of what it was in the past. This decline in the incidence of esophageal SCC parallels an
improvement in the socioeconomic situation of people living in this region. According to recent cancer registry data in
Iran there is still an obvious intracountry variability between the incidence of esophageal cancer in the south with an
ASR of 3 for males and 2 for females in Kerman and 43 and 36 in the northeastern province of Golestan. The reasons
for this very high rate of SCC in northeastern Iran have been the subject of several studies during the past 35 years.
According to results of these studies the suspected risk factors are: low intake of fruits and vegetables, drinking hot
tea, consumption of opium products and tobacco, H.pylori infection in the stomach, using unhealthy drinking water from
cisterns and genetic susceptibility. The main suspected mutagens are polycyclic aromatic hydrocarbons [PAH] and Nnitroso compounds. In order to embark primary and secondary prevention of this fatal cancer, further prospective
studies are presently underway in the region. The Golestan esophageal cancer cohort study which follows of 50,000
subjects is on going. We expect simple and feasible evidence based preventive strategies to be implemented in the
future according to the results of this study.
pathology
Carcinosarcoma of the esophagus.
Zia ur Rehman; Pal, Inam; Ahmed, Zubair; Qureshi, Asim
E-mail:[email protected]
The Aga Khan University Hospital - Department of Surgery
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 282-284 (9 ref.)
Keywords: Carcinosarcoma; Immunohistochemistry
Abstract: Carcinosarcoma of the esophagus is a rare neoplasm characterized histologically by presence of
carcinomatous and sarcomatous elements. Case report of Carcinosarcoma of the esophagogastric junction whose
morphological and immunohistochemical features makes it quite distinctive from other tumours is presented. It was an
ulcerated lesion diagnosed in an elderly Afghan lady located 34 cms from the incisor teeth. The patient was a smoker.
Eye Foreign Bodies
Long-term corneal complication of retained anterior chamber-angle foreign body.
Jastaneiah, Sabah S.
King Khaled Eye Specialist Hospital - Cornea and Anterior Segment Division
Saudi Journal of Ophthalmology 2010; 24 (3): 105-108 (5 ref.)
Keywords: Anterior Chamber; Cornea-pathology; Edema-etiology
Abstract: A 33-year-old patient referred to the cornea and anterior segment department to evaluate inferior corneal
edema related to a retained intraocular foreign body [IOFB] in the anterior chamber-angle. The foreign body, which
was a single piece of glass caused by an exploded light bulb twenty years back, was surgically removed; edema
resolved and vision improved to 20/30. In the presence of an anterior chamber IOFB; long-term adverse effects should
be considered. We would advise removal of the FB regardless of the inertness and location facts, as long as the risk
and benefits of the surgical intervention are carefully evaluated.
Fatty Acid-Binding Proteins
diagnostic use
Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: the
potential for influencing patient management.
Alhadi, Hafidh A.; Fox, Keith A.A.
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 41-49 (14 ref.)
Keywords: Myocardial Infarction-diagnosis; Early Diagnosis; Prospective Studies; Sensitivity and Specificity;
Predictive Value of Tests; Creatine Kinase-diagnostic use
Abstract: The objective of this study was to evaluate the diagnostic value of heart-type fatty acid-binding protein [HFABP] in patients with acute chest pain and compare it with standard cardiac markers. We undertook a prospective
evaluation of 100 consecutive patients admitted with acute chest pain suggestive of acute coronary syndromes [ACS].
Serum cardiac troponin I [cTnI], cardiac troponin T [cTnT], creatine kinase-MB [CK-MB] mass, myoglobin, and H-FABP
were determined at presentation and 2, 4, 8-10, and 16-24 hours after presentation. The main outcome measure was
the best sensitivity value within 6 hours after symptom onset. H-FABP peak concentration occurred at 8 hours after
symptoms onset and was the most sensitive early marker with 79.9% and 98% of patients with AMI identified at
presentation and 2 hours after presentation respectively. The sensitivity of all other cardiac markers [CK-MB mass,
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IMEMR Current Contents
Subject Index
cTnI, cTnT, and myoglobin] at presentation was<62%. The negative predictive value of H-FABP [94%] was also
superior to other markers within the first 2 hours of presentation. Myoglobin was the second most sensitive early
marker at presentation. Peak sensitivity of cTnI, CK-MB mass, and cTnT were present at 4, 8-10, and 8-10 hours
respectively after presentation. Combined measurement of H-FABP and cTnI on two occasions during the first 8 hours
after symptom onset was sufficiently sensitive and specific for the early diagnosis of most patients with acute MI and
may provide advantages over other cardiac marker combinations.
Validity of cardiac markers as diagnostic and prognostic indicators of complications in patients
undergoing percutaneous coronary intervention.
Alhadi, Hafidh A.; Fox, Keith A.A.
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 31-40 (25 ref.)
Keywords: Troponin I-diagnostic use; Troponin T-diagnostic use; Prognosis; Angioplasty, Transluminal,
Percutaneous Coronary; Sensitivity and Specificity; Reproducibility of Results; Prospective Studies; Creatine Kinasediagnostic use
Abstract: The aim of this study was to assess the diagnostic and prognostic value of heart-type fatty acid-binding
protein [H-FABP] in elective percutaneous coronary intervention [PCI] and compare it with standard cardiac markers. A
prospective evaluation was done of 80 consecutive patients admitted for elective PCI. Serum cardiac troponin T
[cTnT], cardiac troponin I [cTnI], creatine kinase-MB [CK-MB mass], myoglobin, and H-FABP were determined preangioplasty and 1, 2, 4, and 16-24 hrs post-angioplasty. Elevated cardiac markers were correlated with demographic,
angiographic and procedural variables. Patients were followed up for 20-26 months. H-FABP peaked early at 2 hours
and was useful for the early detection of evolving AMI within 1-3 hours after angioplasty. Cardiac-TnI, myoglobin, HFABP, CK-MB mass, and cTnT concentrations were elevated in 46.25%, 17.5%, 13.3%, 11.25%, and 7.5%
respectively. Cardiac-TnI was the most sensitive marker for detecting all complications and was superior to all other
markers. Elevated cardiac markers were correlated with old age [P<0.02]; chest pain +/- ECG changes of ischaemia
[P<0.003]; use of stents [P<0.019] and major complications such as major dissection [P<0.004]; transient vessel
closure [P<0.022]; bail out stent [P<0.003], and AMI [P<0.042]. Elevated cardiac markers were associated with a
reduction of event-free survival [16.92 versus 20.67 months, P<0.03]. Heart-type-FABP measurements at 1 hour [or
thereafter] post-PCI may offer an early chance of detecting evolving AMI; cTnI was the most sensitive marker for the
detection of major complications in patients undergoing PCI. Measurements of cTnI 16-24 hours post-PCI should be
part of the routine management of patients following elective PCI.
Fatty Liver
Non-alcoholic fatty liver disease [NAFLD] - is it an emerging risk factor for coronary artery
disease?: preliminary study in a local Indian population.
Thiruvagounder, Manopriya; Khan, Shaheen; Sheriff, Dhastagir S.
University of Calicut - Department of Life Sciences
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 221-226 (26 ref.)
Keywords: Coronary Artery Disease; Risk Factors; Adiponectin; Plasminogen Activator Inhibitor 1; Tumor Necrosis
Factor-alpha; Insulin Resistance; Metabolic Syndrome X
Abstract: The objective of this study was to identify the presence of non-alcoholic fatty liver disease [NAFLD] in
patients with coronary artery disease [CAD]. 149 patients were selected, who had been referred to the Institute of
Cardiology, Banglore, India, between January 2007 and June 2009 and diagnosed with CAD. Four patients did not
participate in the study. Venous blood samples were taken from these cases, and age-matched healthy controls who
came for a master health check-up [N=100]. All were subjected to routine liver function tests including serum
transaminases, enzyme immunoassays for plasminogen activator inhibitor I [PAI-I], C reactive protein [CRP], and
tumour necrosis factor-alpha [TNF-alpha]. Using ultrasonography and serum alanine aminotransferase [ALT] levels,
the presence of NAFLD in CAD patients was reported. CAD patients with NAFLD had significantly higher liver enzymes
and marginally higher A1C levels compared to control subjects. Levels of TNF-alpha and PAI-I were higher in CAD
patients with NAFLD compared to both female and male controls [P <0.1 and P <0.05]. Levels of CRP [P <0.01 in both
groups] and uric acid were increased in both group of patients [P <0.05 and P <0.01 in male and female patients,
respectively]. Levels of adiponectin were significantly reduced in the patients compared to the controls [P <0.05 and P
<0.001] in male and female patients respectively. The increased serum levels of PAI-I and TNF-alpha reflected the
proinflammatory status in these CAD patients which may be due to the presence of NAFLD. This could contribute
additively to the development of cardiovascular events [CVD].
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Fissure in Ano
surgery
Fissurectomy with posterior midline sphincterotomy for management of chronic anal fissure.
Memon, Abdul Sattar; Siddiqui, Faisal Ghani; Hamad, Adeel
E-mail:[email protected]
Liaquat University of Medical and Health Sciences - Department of Surgery
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 229-231 (26 ref.)
Keywords: Treatment Outcome; Chronic Disease
Abstract: To determine the efficacy and safety of fissurectomy with posterior midline Sphincterotomy in the
management of chronic anal fissure in terms of symptomatic relief, complications and recurrence. Observational caseseries. Department of Surgery, Liaquat University Hospital, Jamshoro/Hyderabad, for a period of 3 years from January
2005 to December 2007. A total of 136 patients with chronic anal fissure were recruited for this study. All subjects
underwent elective fissurectomy and posterior Sphincterotomy. Surgery was performed either under spinal or general
anaesthesia. Symptomatic relief and early postoperative complications were recorded. The patients were followed for
18 months. Follow-up included assessment for complications such as pain, incontinence, keyhole deformity, and
recurrence. All patients presented with pain during and after defaecation. Forty [29.4%] patients presented with
bleeding per rectum. One hundred and sixteen [85%] patients complained of perianal swelling while 8 [5.9%] patients
complained of perianal itching. Retention of urine was the most common postoperative complication, seen in 10 [7.4%]
cases. It occurred within the first 24 hours after operation and all cases required catheterization. Six [4.4%] patients
complained of moderate to severe postoperative pain in the first 24 hours, requiring narcotic analgesics. Transient
incontinence of flatus and faeces occurred in 5 [3.7%] and 3 [2.2%] cases respectively. One patient presented with a
recurrent anal fissure after 8 months but responded to conservative treatment. Given the low rate of complications and
almost negligible rate of recurrence, fissurectomy with posterior midline Sphincterotomy is still a treatment of choice for
the management of chronic anal fissure.
Fluoroquinolones
pharmacology
Antimicrobial susceptibility testing of newer quinolones against gram positive and gram
negative clinical isolates.
Iffat, Wajiha; Shoaib, Muhammad Harris; Muhammad, Iyad Naeem; Rehana; Tasleem, Samiah; Gauhar, Shahnaz
E-mail:[email protected]
Dow Medical University - Dow College of Pharmacy
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 245-249 (22 ref.)
Keywords: Ofloxacin-pharmacology; Microbial Sensitivity Tests; Gram-Negative Bacteria-drug effects; GramPositive Bacteria-drug effects; Drug Resistance, Bacterial
Abstract: Antibiotic resistance development is an ongoing process associated with irrational antibiotic use. WHO
recommends regular surveillance programs for monitoring of antibiotic resistance. The present study is a step in this
direction. A total of 124 clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae and
Pseudomonas aeruginosa were collected from different hospitals in Karachi. In vitro antimicrobial susceptibility studies
were carried out by agar dilution method using newer quinolones that included Gatifloxacin and Levofloxacin. It was
observed that 50% [n=30] isolates of Staphylococcus aureus were resistant to gatifloxacin. Gatifloxacin was more
active against Pseudomonas aeruginosa [n=23] and showing complete susceptibility with MIC 1mg/L except for three
very resistant strains that shown resistance at even higher concentrations. Escherichia coli [n=45] has shown 15.5%
and Klebsiella pneumoniae [n=26] 34.61% resistance to gatifloxacin. Levofloxacin was more active against
Staphylococcus aureus and Escherichia coli showing complete susceptibility at 0.5 mg /L concentration. Pseudomonas
aeruginosa and Klebsiella pneumoniae were found to be resistant to Levofloxacin showing 36.36% and 23.08%
resistance respectively. The study strongly recommends the adherence to the antibiotic policy and regular
susceptibility testing to overcome the problem associated with antimicrobial resistance.
Food Microbiology
Microbilogical quality of home cooked meat meals and vegetable salads.
Elmacioglu, Funda; Tayfur, Muhittin; Bener, Ozgun; Akman, Mehmet; Aksoydan, Emine
Ondokuz Mayis University - Samsun Health Vocational High School
Pakistan Journal of Medical Sciences 2010; 26 (2): 416-419 (28 ref.)
Keywords: Food Contamination; Vegetables-microbiology; Meat-microbiology
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Abstract: To determine the microbiological quality of home meals and salads samples. A total of 180 samples were
collected between May 2007 and July 2007 in Ankara, Turkey. The samples were analysed for the presence of total
aerobic bacteria [TAB], thermotolerant coliform bacteria [TCB], Esherichia coli, Salmonella spp. and Staphylococcus
aureus. In the present study, S.aureus, coliforms, E.coli, and Salmonella were not detected in cooked meat meals
samples. TAB was detected in 22 [24.4%] meat dishes ranges 102-104. The cooked meat dishes samples were
analyzed for the presence of TCB, and detected in 2 [2.2%] meat dishes ranges 103-104. Numbers of the aerobic
mesophilic bacteria ranged from 102 to 105 cfu/g and coliforms from 37 to 1400 MPN/g in 17 [18.9%] of salad
samples. E.coli was detected at level 102-103 [n=12, 13.3%] and S. aureus was detected in 9 [10.0%] at levels of 103104 cfu/g salad samples tested. In 4 [4.4%] of the salads samples S.aureus and E.coli were isolated together. The
results indicate that the type of vegetable salads analysed may contain pathogenic bacteria and thereby represent a
risk to the consumers in regard to foodborne diseases. Thus, it remains essential to include the significance of effective
hygiene practices as an important safety measure in programmes of home hygiene, consumer education, and advice.
Food-Drug Interactions
Studies of food drug interactions.
Aman, Syed Faisal; Hassan, Fouzia; Naqvi, Baqar S.; Hasan, Syed Muhammmad Farid
E-mail:[email protected]
University of Karachi - Faculty of Pharmacy - Department of Pharmaceutics
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 313-320 (55 ref.)
Keywords: Biological Arialability; Area Under Curve
Abstract: Medicines can treat and alleviate many diseases provided that they must be taken properly to ensure that
they are safe and useful. One issue related with the medicines is that whether to take on empty stomach or with food.
The present work gives information regarding food-drug interactions that were studied by collecting seventy five
prescriptions from various hospitals. In most of the collected prescriptions, food-drug interactions were detected using
the literature available. It was also found that only few studies have been carried out so far on the effect of food on
drug disposition in the Asian population. Thus more studies on food-drug interactions particularly in the local population
is recommended in order to determine the effect of food and food components on drug disposition and to the kinetics of
the drugs which has not yet well highlighted in this part of the world.
Foreign Bodies
complications
Iatrogenic foreign body from left to right bronchus: the lessons learnt.
Mohamad, Irfan; Mohamad, Hazama; Ismail, Hashimah; Khamis, Nadzman; Othrub, Khaled
E-mail:[email protected]
University Sains Malaysia - School of Medical Sciences - Department of Otorhinolaryngology
Pakistan Journal of Medical Sciences 2010; 26 (2): 482-484 (7 ref.)
Keywords: Bronchi; Iatrogenic Disease; Bronchoscopy
Abstract: Iatrogenic foreign body in the airway is a known complication of medical treatment that may occur in
various clinical settings. The foreign material can be from extraluminal or intraluminal source. The symptoms may
manifest acutely or months and years after treatment. Our case highlighted the possibility of the dislodgement of the
foreign body during retrieval from the initial site, and the importance of prompt identification and management.
Foxes
Parasitology
Studies on intestinal helminthes infecting free-ranging red fox [vulpes vulpes] in north-western
part of Libya.
Hosni, M.M.; El Maghrbi, A.A.
Alfatah University - Faculty of Vet. Medicine - Department of Preventive Medicine
Veterinary Medical Journal 2009; 57 (1): 59-66
Keywords: Helminths; Intestinal Diseases, Parasitic; Cestode Infections
Abstract: Eighteen free-ranging live red fox [Vulpes vulpes] captured during the period ringed from October 2007 to
April 2008 from rural and semi-desert regions of North-Western part of Libya were investigated parasitologically for
presenceof intestinal helminthes. The study revealed that 2 foxes [11.1%] were free from intestinal helminthes and 16
foxes [88.9%] were infected with helminth parasites species. These helminthes were four cestodes: joyeuxiella
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echinorhynocoides 5[31 .25%], mesocestoides spp. 6[37.5%], diplopylidium nolleri 2[1 2.5%] and dipylidium caninum
1[6.25%].Three nematodes: Rictularia caherrsis 3[1 8.7%], Ancylostomacaninum 3[18.7%] and Toxocara canis
2[12.S%].Only one acanthoeephala: moniliformis dubius 4[25%]. No trematodes were found. All these helminthes were
recovered and reported for the first time from red fox [Vulpes vulpes] in north-western part of Libya. Five helminthes of
them has zoonotic important. Therefore, the study showed that the red fox [Vulpes vulpes] plays an important role in
the investigated area as a reservoir host of a number of parasites of domesticated and wild animals or may have
zoonotic importance. The results were discussed with reference to variations in the live behavior and diet in the rural
areas of North-western part of Libya.
Ganglioneuroma
diagnosis
Primary orbital ganglioneuroma in a 2-year-old healthy boy.
Al Khiary, Hattan; Ayoubi, Ayman; Elkhamary, Sahar M.
King Khaled Eye Specialist Hospital - Oculoplastic and Orbit Division
Saudi Journal of Ophthalmology 2010; 24 (3): 101-104 (12 ref.)
Keywords: Ganglioneuroma-pathology; Orbital Neoplasms-pathology; Exophthalmos-etiology; Biopsy
Abstract: A 2-year-old healthy child presented with progressive unilateral proptosis. Complete work up including:
general examination, detailed ophthalmic evaluation and radiological imaging were done. He underwent orbital
exploration via anterior orbitotomy incision and debulking of the tumor was done. The histopathological examination
confirmed the diagnosis of orbital ganglioneuroma. Ganglioneuroma is an unusual benign tumor of neuroplastic origin
with extremely rare orbital involvement with only one prior reported case in a youth. The tumor is slow growing and
non-metastasizing. Biopsy is necessary to differentiate it from the malignant neuroblastoma and excision is usually
curative.
Gangrene
etiology
Neonatal gangrene of the extremity: a complication of umbilical catheterization.
Mousavi, Seyed Abdollah; Sahebpour, Alireza Alam; Shahmohammadi, Soheila
E-mail:[email protected]
Mazandaran University of Medical Sciences - Faculty of Medicine - Department of Pediatric Surgery
Pakistan Journal of Medical Sciences 2010; 26 (2): 488-489 (9 ref.)
Keywords: Catheterization-adverse effects; Lower Extremity-pathology; Umbilical Veins
Abstract: We report a case of severe tissue ischemia after umbilical catheterization in a preterm newborn. Umbilical
catheters can accidentally enter branches of the iliac artery during attempted placement in the umbilical vein. If these
misplacements are not recognized by radiology and promptly corrected, arterial obstruction may lead to ischemia and
infarction of the extremities. This is the first report of below-knee gangrene due to peripheral vasospasm or thrombosis
occurring after umbilical vein catheterization [UVC]. We discuss that the radiographic verification is essential before
infusing medications.
Glaucoma
complications
[Annual world glaucoma day. Enhancing awareness of glaucoma: a leading cause of preventable
blindness].
Sbeity, Zaher; Ritch, Robert
E-mail:[email protected]
Einhom Clinical Research Center - Department of Ophthalmology
LMJ - Lebanese Medical Journal 2010; 58 (2): 120-121 (6 ref.)
Keywords: Glaucoma-epidemiology; Glaucoma-prevention and control; Blindness-etiology; Blindness-prevention
and control; Awareness
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Glucagonoma
diagnosis
A case of gllucagonoma and a review the literature.
Breizat, Abdel Hadi; Al Tahieneh, Amal S.
E-mail:[email protected]
Ministry of Health - Al Bashir Hospital - Department of Surgery
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 70-74 (15 ref.)
Keywords: Glucagonoma-pathology; Glucagonoma-surgery; Neoplasm Metastasis; Prognosis; Glucagonoma-drug
therapy; Streptozocin-therapeutic use; Treatment Outcome
Abstract: Glucagonoma is a rare islet cell tumor [alpha cell tumor] of the pancreas, when active it produces a
syndrome characterized by necrolytic migratory erythema, diabetes mellitus, weight loss, anemia, glossitis,
thromboembolism, neuropsychatric disturbances and hyperglucagonaemia. We present a case of a large pancreatic
head tumor with diabetes mellitus [DM], anemia, weight loss and muscle wasting. After complete resection of the
pancreatic tumor, the hyperglycaemia subsided. Peviewing 120 cases of glucagonoma in the literature the average
tumor diameter was 3.6 cm. Most of the tumors [90%] occurred in the body and the tail. Two thirds of the reported
glucagonomas were malignant and 53.3% metastasizes to other organs. Necrolytic migratory erythema [NME] is not a
prerequisite for the diagnosis of Glucagonoma syndrome, where anemia, hyperglycemia, muscle wasting and weight
loss may be the presenting features.
Graves Ophthalmopathy
radiotherapy
[Corticosteroids and radiotherapy in the treatment of graves-ophthalmopathy].
Nasr, E.; Khater, S.; Nehme Nasr, D.; Azoury, F.; Jambart, S.
E-mail:[email protected]
CHU Hotel-Dieu of France - Department of Endocrinology
LMJ - Lebanese Medical Journal 2010; 58 (2): 86-90 (16 ref.)
Keywords: Graves Ophthalmopathy-drug therapy; Treatment Outcome; Steroids-therapeutic use; Quality of Life;
Retrospective Studies
Abstract: Graves ophthalmopathy is a debilitating disease impairing the quality of life of affected individuals. The
management of moderate-to-severe active Graves' ophthalmopathy is a major therapeutic challenge, and the
treatment outcome is often unsatisfactory. We have carried out a retrospective study to assess the efficacy of
combined orbital irradiation and systemic corticosteroids. Ten patients were included; all patients had received 20
Grays to the retrobulbar tissues in ten fractions, and oral or intravenous glucocorticoids. The main therapeutic outcome
measures were the criteria of Donaldson and co-workers and a self-assessment evaluation. The quality of life outcome
was also evaluated by the GO-QOL [Graves' ophthalmopathy quality of life] questionnaire. Seven patients [70%]
demonstrated improvement in ocular parameters; the response was excellent in three cases, good in three cases and
fair in one case. Three patients showed no response to the treatment. The self-assessment evaluation showed that
75% of patients were satisfied with the results of the treatment. Proptosis was the most responsive sign to radiation
and steroids. A duration of the eye disease of more than 18 months was associated with less improvement and a
higher failure of the treatment. Concerning the quality of life, the score for visual fonctionning was 88.2 +/- 18.2 after
treatment, while the score for appearance was 63.3 +/- 23.3. In conclusion, a combination of orbital irradiation and
systemic steroids is associated with 70% of favorable responses, but the quality of life is not restored in the same
proportions and remains impaired after treatment.
Growth
Growth pattern and sexual maturation in type 1 diabetic patients Erbil city-Iraq.
Ahmed, Abbas Abdulkader
E-mail:[email protected]
Hawler Medical Uuniversity - College of Medicine
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 42-47 (30 ref.)
Keywords: Sexual Maturation; Diabetes Mellitus, Type 1-complications; Reference Values; Prospective Studies;
Case-Control Studies; Body Mass Index
Abstract: The aims of this study were to assess the physical growth and pubertal maturation in a group of children of
type 1 diabetes mellitus compared with controls. In this case-control study, physical growth assessment and sexual
maturity rating of 40 patients aged 8-18 years [26 males, 14 females] with established type 1 diabetes were compared
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with those of 40 healthy controls of the same age and gender. Assessment of height, weight, Body Mass Index [BMI]
and Sex Maturity Rating [SMR] were studied in comparison to a matched age group. The height of 10 patients [25%]
was less than 5th percentile, twenty nine patients [72.5%] were between 5-75th percentile and one [2.5%] above 75th
percentile in comparison with the results of the controls: one [2.5%], 23 [57.5%] and 16 [40%] respectively. The weight
of 11 patients [27.5%] was less than 5th percentile, twenty six patients [65%] were between 5-75th percentile and three
patients [7.5%] above 75th percentile in comparison with the results of the controls: one [2.5%], 25 [62.5%] and 14
[35%] respectively. The mean BMI was 19.52 +/- 3.48 in patients whereas in the control group it was 21.41 +/- 4.80.
The mean age of starting menarche in diabetic patients was 13.30 +/- 1.15 years in comparison to 12.69 +/- 0.85 years
of controls. Twenty four diabetic patients [60%] had normal SMR compared to 35 [87.5%] of controls, and sixteen
patients [40%] had delayed SMR compared to 5 [12.5%] of controls. It is concluded that diabetic children [type 1] are
associated with impairment of physical growth and delayed sexual maturation.
Guillain-Barre Syndrome
microbiology
Campylobacter jejuni infection and childhood guillain-barre syndrome.
Barzegar, Mohammad; Hashemilar, Mazyar; Bonyadi, Mohammad Reza
Tabriz University [Medical Sciences] - Pediatric Health Research Centre - Department of Pediatric Neurology
Pakistan Journal of Medical Sciences 2010; 26 (2): 304-309 (29 ref.)
Keywords: Campylobacter Jejuni; Campylobacter Infections-epidemiology; Prognosis; Prospective Studies; CaseControl Studies
Abstract: Guillain-Barre syndrome [GBS], acute postinfectious polyneuritis, is the most common cause of acute
neuromuscular paralysis. Infection with Campylobacter jejuni is recognized as a common antecedent of the GBS. This
study aimed to determine the frequency of this infection in children with GBS and, the clinical and epidemiologic
features of this association. We performed a prospective case-control study on a cohort of 47 children with GBS
admitted to Tabriz Childrens Hospital in the northwest of Iran between July 2006 and July 2008. Serologic
investigations were used to diagnose preceding C. jejuni infection. We found evidence of recent C. jejuni infection in
40.4% of the patients with GBS, as compared with 6.1% in household controls [odds ratio 10.5, 95% CI: 2.2-49.2,
P<0.001]. Duration to achieve independent walking was longer in C. jejuni-associated patients [P<0.013]. However
95% of C. jejuni-associated GBS patients achieved independent walking at end of one year. The patients with
preceding C jejuni infection were more likely to have axonal neuropathy [P<0.05]. Campylobacter jejuni infection is an
important antecedent illness in childhood Guillain-Barre syndrome in Iranian children, and is associated with good
prognosis.
Head and Neck Neoplasms
drug therapy
Squamous cell carcinoma of the head and neck: dramatic response to chemoradiotherapy.
Mosalaei, Ahmad; Hashemi, Seyed Basir; Sedaghat, Sanaz
E-mail:[email protected]
Shiraz University of Medical Sciences - Nemazee Hospital - Department of Radiation Oncology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 55-57 (5 ref.)
Keywords: Head and Neck Neoplasms-radiotherapy; Carcinoma, Squamous Cell-drug therapy; Carcinoma,
Squamous Cell-radiotherapy; Treatment Outcome
Health Manpower
Re: Afghanistan and Oman: personal reflections on a profound contrast.
Alshishtawy, Moeness
E-mail:[email protected]
Ministry of Health - Department of General of Planning
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 272-275 (13 ref.)
Keywords: Health Personnel; Students, Medical; Nurses; Physicians
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Health Personnel
Attitudes of health caregivers on teamwork and safety climate in an educational medical center.
Mahfoozpour, Soad; Mojdehkar, Reyhaneh
E-mail:[email protected]
Shahid Beheshti University of Medical Sciences - Faculty of Health
Pakistan Journal of Medical Sciences 2010; 26 (2): 450-453 (14 ref.)
Keywords: Attitude; Questionnaires; Patient Care Team; Safety; Occupational Health
Abstract: To study the attitudes of health caregivers on teamwork and safety climate in an educational Medical
Center in Tehran Iran. In this descriptive study, 225 residents physician, nurses and other paramedics working for at
least one month in the studied hospital participated. Data collection tool was Safety Attitudes Questionnaire [SAQ]
which consisted of three sections: provider group characteristics, 14 teamwork questions, and 13 safety climate
questions. Validity [content] and reliability [test-retest] of the questionnaire were confirmed and chi square test was
used for data analysis. The results indicated that from 225 subjects, 39.11% were male and 60.89% were female, with
70.23% being married and 26.66% being single. There was not a significant relationship between caregivers' attitudes
on teamwork and safety climate with provider group characteristics [gender, experience in organization, marital status,
and organizational position]. By comparing teamwork and safety climate points, the status of teamwork in the studied
hospital was better than that of safety climate and the caregivers were more satisfied with status of teamwork in the
hospital. Achievement of patient safety depends on teamwork. Safety climate also leads to an appropriate feedback
and culture of learning from errors. Therefore, further studies on safety climate related factors, for continuous
improvement in patient safety is recommended.
Health Services Research
National research for health system mapping in 5 countries in the Eastern Mediterranean Region
and perspectives on strengthening the systems.
Ghannem, Hassen; Becerra Posada, Francisco; Ijsselmuiden, Carel; Helwa, Iman; Haan, Sylvia
E-mail:[email protected]
University Of Sousse - Faculty of Medicine - Department of Epidemiology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 260-261 (5 ref.)
Keywords: Health Planning; World Health Organization; Health Systems Plans
Hearing
Hearing health practices and beliefs among over 20 year-olds in the Omani population.
Khandekar, Rajiv; Ved, P. Narang; Kantharaju, K.K.; Mane, Pratibha; Hassan, Abdul R.M.; Niar, Raghunandan; Fahim,
A. Shah; Al Khabori, Mazin; Al Harby, Saleh
E-mail:[email protected]
Ministry of Health - Eye and Ear Health Care - Department of Non-Communicable Disease Control
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 241-248 (25 ref.)
Keywords: Health Knowledge, Attitudes, Practice; Culture; Questionnaires; Noise; Hearing Loss
Abstract: The objective of this study was to investigate hearing health practices and beliefs among people over 20
years old in the Omani population. This descriptive study was conducted in Oman during 2007-2008. Arabic speaking
health staff interviewed a total of 598 selected people from urban and rural Oman and also industrial workers using a
closed ended questionnaire with 15 questions. Participants' responses to the hearing practice related questions were
graded into excellent [>/=20 points], average [10 to 19] and poor [<10 points]. The responses to the questions about
hearing beliefs were grouped into excellent [>/=25 points], good [5 to 24], average [-4 to 4], poor [-24 to -5] and very
poor [<-25] grades. We calculated the frequencies, percentage proportions and 95% confidence intervals of the
different grades of beliefs and hearing practice. The rates were also compared among different subgroups. We
performed regression analysis to identify predictors of good hearing practice and scientific beliefs. Among the 598
participants, an 'excellent' grade of hearing practice and belief was noted in 386 [64.5% [95% CI 60.7-68.4]] and
average in 205 [34.3% [95% CI 29.5 - 37.1]]. Being in the 20 to 39 years age group [OR=1.67] and an urban resident
[OR=0.53] were both predictors of an excellent grade of hearing practice, while male gender [OR=1.71] and illiteracy
[OR=1.80] were predictors of scientific beliefs. We noted high levels of good hearing practice and low levels of modern
scientific beliefs among Omani participants. The Ear Health Care program of Oman should focus on improving the
knowledge about healthy hearing so that attitudes and hearing practices are improved and noise-induced hearing loss
can be prevented or delayed.
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Hearing Loss, Sensorineural
epidemiology
Sensorineural hearing loss in patients with diabetes mellitus.
Yaseen, Ehab Taha; Abed, Ali
E-mail:[email protected]
Al Mustansiriyah Uuniversity - College of Medicine - Department of Surgery
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 32-37 (21 ref.)
Keywords: Hearing Loss, Sensorineural-Diabetes Mellitus; Diabetes Complications; Time Factors
Abstract: The aim of this study was to find cause effect relationship between diabetes and sensorineural hearing
loss. Hearing threshold of 70 diabetic patients and 70 healthy controls were determined using pure tone audiometry at
Al Yarmouk Teaching hospital. Their ages ranged between [9-45] years old. The patients were categorized into groups
according to their age, the duration of disease, complications, control and type of diabetes. These observations were
compared with those from the control subjects using appropriate statistical methods. The results of the study revealed
that mean hearing threshold was worse in diabetic patients than control subjects. All age groups with diabetes showed
significant low and high frequency hearing loss as compared to those who were well controlled. The threshold was
worse in complicated diabetics than in non complicated diabetics. Diabetics with longer duration shows worse
threshold than others. However, threshold was better in patients with good control of diabetes and there were no
differences in threshold between insulin and non insulin dependent diabetes. It was found that diabetics had a poorer
hearing threshold which was seen in all age groups, and there was a relationship between the duration, control and
complications of diabetes and the level of hearing loss. No significant difference in hearing loss was found between
insulin-dependent and non-insulin dependent diabetics.
Heart Defects, Congenital
surgery
Prevalence and risk factors of mortality after surgery for congenital heart disease in Tabriz, Iran:
a five year retrospective analysis.
Sohrab, Negargar; Alireza, Yagoubi; Ata, Mahmoodpoor; Mahmoud, Samadi; Bahram, Qaderi; Azad, Rahmani;
Etemadi, Sahar
Tabriz University of Medical Sciences - Department of Anesthesiology
Pakistan Journal of Medical Sciences 2010; 26 (2): 267-270 (16 ref.)
Keywords: Cardiovascular Surgical Procedures-methods; Prevalence; Risk Factors; Retrospective Studies; Mortality
Abstract: The mortality rate after surgeries for congenital heart disorders is the most important factor for
determination of the quality of these operations. A study that evaluate the mortality rate of these surgeries has not
been done till now in Iran. Therefore, the purpose of this study was to determine the prevalence and risk factors of
mortality after surgery for correction of congenital heart disease. In a retrospective study, 120 children who expired
after cardiac surgery and also 150 children who survived after surgery were evaluated between 2005 and 2009.
Personal and Social parameters and some risk factors were analyzed. Analysis of results was performed using SPSS
version 14 and descriptive and inferential statistics. It showed that 12.64% of children died after surgery. Important risk
factors of death were age, weight, height, body surface, preoperative Blood Urea Nitrogen, preoperative Prothrombin
Time, preoperative cyanosis and postoperative bleeding. The results of this study indicate that the death rate of
children after heart surgery in cardiovascular center of Tabriz Medical University seems to be high. Because of the lack
of studies in this field more trials are advised.
Hepatitis B Surface Antigens
blood
Prevalence of hepatitis B surface antigen and hepatitis C virus antibodies among blood donors
in Alexandria, Egypt.
Wasfi, O.A.S.; Sadek, N.A.
University of Alexandria - High Institute of Public Health - Department of Microbiology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 238-242 (33 ref.)
Keywords: Hepatitis C Antibodies-blood; Blood Donors; Prevalence; Cross-Sectional Studies; Enzyme-Linked
Immunosorbent Assay; Seroepidemiologic Studies
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Abstract: Hepatitis B and C virus infections are common serious complications of blood transfusion. Over a 6-month
period in 2007/08 all samples from a blood bank in Alexandria, Egypt [n=3420] were tested for hepatitis B surface
antigen [HBsAg] and anti-hepatitis C virus [HCV] antibodies. A total of 119 donors [3.5%] were positive for anti-HCV
and 47 [1.4%] for HBsAg. The mean age of HCV - positive donors was significantly higher than HBV-positive donors:
35.7 [SD 83] versus 29.9 [SD 7.4] years, HCV and HBV prevalence was highest among males [93.3% and 93.6%
respectively], in urban areas [66.4% and 80.9%] and among manual workers [64.7% and 46.8%]. The rates were lower
than previous studies in Egypt, perhaps due to predonation screening which excludes those known to be at high risk of
contracting bloodborne infections or who had other contraindications to blood donation.
Hepatitis B Vaccines
Hepatitis B vaccination coverage among Iranian children aged 15-26 months in 2006.
Esteghamati, A.; Keshtkar, A.A.; Nadjafi, L.; Gouya, M.M.; Salaramoli, M.; Roshandel, Gh.; Yaghini, F.
Ministry of Health and Medical Education - Centre for Disease Control and Prevention - Office of Vaccine Preventable
Diseases
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 93-100 (29 ref.)
Keywords: Vaccination-utilization; Questionnaires
Abstract: This study in 2006 estimated the hepatitis B virus [BHV] vaccination coverage in the Islamic Republic of
Iran at the national and district levels in urban, rural and remote populations of 41 university health service areas. Of 21
905 children recruited to the study, vaccination coverage based on vaccination card records was 100% in 14,15 and 10
of the 41 university areas for the 1st, 2nd and 3rd doses of HBV respectively. National levels of HBV1, HBV2 and
HBV3 coverage were 98.9%, 98.8% and 98.4% respectively. The lowest HBV vaccination coverage rate was 90.7% [in
a remote district]. HBV vaccination coverage was at an acceptable level in Iranian children.
Hepatitis C Antibodies
The prevalence of HCV antibodies in skin disease patients in Saudi Arabia.
Halawani, Mona; Balbisi, Amal; Alotaibi, Hend; Alsaif, Fahed; Bakir, Talal M.
E-mail:[email protected]
King Khalid University Hospital - Department of Dermatology
SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 35-39 (29 ref.)
Keywords: Skin Diseases-virology; Prevalence; Prospective Studies; Polymerase Chain Reaction; Hepatitis Cepidemiology
Abstract: Hepatitis C virus [HCV] infection is a worldwide health issue with about 3% of the world's population having
HCV. In Saudi Arabia, prevalence ranges from 1.0% to 5.87%. Cutaneous diseases can indicate the presence of HCV
infection. The research project aims to identify prospectively the prevalence of HCV infection in 200 patients with
various types of skin disorders and 50 healthy blood donors, and to quantify this association through clinical and
laboratory investigations. Two hundred patients with cutaneous manifestations who presented at the Dermatology
outpatient clinics of King Khalid University Hospital [KKUH] and King Abdulaziz University Hospital [KAUH], Riyadh,
and 50 healthy blood donors were prospectively studied. Patients were examined by a team of dermatologists and
clinical data were collected through a standard questionnaire. Ten milliliters of venous blood were collected from fully
consented, 8-1 Oh fasting patients and serum was analyzed for AST, ALT, double infection with HBsAg, anti-HCV
antibodies, and screened for HCV-RNA-PCR. Patients from the study [n = 200] consisted of 25 [12.5%] males and 175
[87.5%] females, with a mean age of 42.9 +/- 15.06 years. Clinical examinations revealed that [35%] had urticaria,
followed by pruritus [28%], lichen planus [25.5%], prurigo [10%], and palpable purpura [1.5%]. The main serum levels
of ALT and AST were within the normal reference ranges. Twenty-four patients [12%] tested positive for anti-HCV
antibodies, with 15 [62.5%] being positive for the presence of HCV-RNA by PCR and 9 [37.5%] resulting negative for
the viral RNA. Of the 24 anti-HCV positive patients, pruritus 12 [50%], urticaria 5 [20.8%], lichen planus 5[20.8%], and
palpable purpura 2[8.3%]. Five [2.5%] patients were positive for HBsAg, with 3 [60%] having pruritus and 2 [40%]
presenting with urticaria. Of the 50 healthy blood donors, only one [2%] tested positive for the presence of anti-HCV
antibodies, and all the donors tested negative for HBsAg. Results clearly indicate the prevalence of anti-HCV
antibodies in 24 out of 200 patients [12%] with skin manifestations seen at the dermatology outpatient clinics and
documented with HCV-RNA-PCR positivity of 15/24 [62.5%]. A p-value of <0.05 was considered significant, therefore,
it is suggested that patients presenting with urticaria, pruritus and LP be investigated to exclude the possibility of HCV
infection.
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immunology
Sero-prevalence of hepatitis C antibodies in the people visiting roadside barbers.
Makheja, Kirpal Das; Abro, Ali Hassan; Kumar, Susheel
E-mail:[email protected]
Jinnah Postgraduate Medical Center [JPMC] - Department of Medicine
Pakistan Journal of Medical Sciences 2010; 26 (2): 402-406 (24 ref.)
Keywords: Hepatitis C-epidemiology; Prevalence; Seraepidemiologic Studies; Barbering; Enzyme-Linked
Immunosorbent Assay
Abstract: Sharing of blades and shaving kits, especially unsterilized ones are known risk factors for the transmission
of Hepatitis C. The objective of this study was to determine the prevalence of Hepatitis C antibodies reactivity among
the patients admitted due to any medical condition and who have been visiting roadside barbers. This was a
descriptive study conducted from July 2007 to June 2008 in the Medical Unit-111, Jinnah Postgraduate Medical
Center, Karachi. The study was designed to include patient's demographics [age, occupation, marital status and
education], clinical information and duration of the visits to roadside barbers with an approximate frequency of shavings
per month. The patients with history of>3 visits to a roadside barber during the last six months were included in the
study. Whereas, the patients with history of liver disease, blood transfusion, surgery, dental treatment, tattoo marks,
intravenous drug use, on regular injectable medicine [like insulin, etc], multiple sexual partners and on haemodialysis
were excluded from the study. A blood sample was collected at the time of admission and the screening for HCVantibodies was done by Enzyme Linked Immuno-Sorbant Assay [ELISA]. A total of 184 male patients were included in
the study. The mean age+ SD of the patients under the study was 33.8+13.2 years. The majority of study patients were
uneducated and belonged to low socioeconomic group. Out of 184 patients, 70 [38%] were found to be HCVantibodies reactive. In comparison to younger patients [age<40 years], the older patients as well as those with history
of longer duration of visits to roadside barbers had high prevalence of HCV-antibodies reactivity, P.015 and P.02
respectively. There was no statistical significant difference for the prevalence of HCV-antibodies reactivity among the
different socioeconomic groups, educational level and marital status. In the present study, it is concluded that the
sharing of unsterilized shaving kits and used blades by roadside barbers are the main sources for the transmission of
HCV. The transmission rate of HCV infection increases with the duration and multiple exposures for shaving.
Hepatitis C, Chronic
Clinical significance of plasma homocysteine concentration in chronic hepatitis C patients with
liver cirrhosis.
Taba, Khalid; El Shayeb, Ayman; Shafeh, Reem; Deghady, Akram; Zein Eldin, Soheir
Alexandria University - Faculty of Medicine - Department of Tropical Medicine
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 755-760 (24 ref.)
Keywords: Liver Cirrhosis; Homocysteine-blood; Liver Function Tests-blood; Folic Acid-blood; Vitamin B 12-blood;
Disease Progression; Kidney Function Tests
Abstract: Homocysteine [Hcy] is a sulfur containing amino acid that is formed as an intermediate in methionine
metabolism. Extensive evidence shows that hyperhomocysteinemia is considered an independent risk factor for
atherothrombotic vascular disease. Methionine metabolism occurs mostly in the liver. Altered methionine metabolism,
in advanced liver disease, may play a pathogenic role. The aim of this work was to evaluate the clinical significance of
plasma Hcy concentration in chronic hepatitis C patients with liver cirrhosis. Twenty male patients [mean age 43.13 +/7.02 year] with chronic hepatitis C with liver cirrhosis [Group I] and 10 healthy age-matched control subjects [Group II]
were included into the study. Ten patients with liver cirrhosis were diagnosed with hepatorenal syndrome [HRS] [Group
Ia] and 10 did not have FIRS, Liver function, renal function tests, urinalysis, HCV Ab, HCV-PCR, plasma folate, B12
and Hcy concentration, abdominal ultrasound were performed for all studied subjects. Plasma Hcy concentration was
significantly elevated in cirrhotic patients compared to healthy controls [P<0.05]. Hcy was positively correlated with the
severity of liver disease as expressed by the Child score [P<0.05]. Plasma Hcy concentration was significantly higher
in patients with HRS than in patients without HRS [P<0.05], and inversely correlated with the creatinine clearance rate
[P<0.05]. There was no significant difference in folate and B12 levels between patients and controls. Plasma Hcy is
elevated in patients with chronic hepatitis C and liver cirrhosis, and correlated with the progression of liver disease,
Patients with cirrhosis complicated with HRS have higher Hcy concentration compared to patients with normal renal
functions, and Hcy level increases with the deterioration of renal function.
39
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Subject Index
Hernia, Ventral
etiology
Port site herniation of the small bowel following laparoscopic-myomectomy: a case report.
Elshafie, Ghazi A.; Al Wahaibi, Khalifa; Al Azri, Ahmed; Al Qadhi, Hani; Al Harthi, Abdullah
Sultan Qaboos University Hospital - Department of Surgery
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 106-110 (18 ref.)
Keywords: Laparoscopy-adverse effects; Abdominal Wall; Uterus-surgery; Hysteroscopy
Abstract: Bowel herniation, through fascial defects secondary to laparoscopic surgery at the site of trocar entry, is a
rare, but potentially serious, complication. Closure of the fascia at port sites measuring 10mm or more has been highly
recommended to avoid such complications. We report a case of a small bowel which herniated and strangulated
through the port site immediately after laparoscopic myomectomy. Resection of the strangulated bowel with primary
anastomosis was required to manage this complication. We present this case report with literature review to discuss
the risk factors and the methods to prevent such a complication post laparoscopic surgery.
Homocysteine
drug effects
Effect of low-dose folic acid supplementation versus HRT and combination of folic acid and HRT
on plasma level of homocysteine in postmenopausal women.
Nasrolahi, Shahla; Radnia, Nahid; Neghab, Nosrat; Shafie, Akram
Hamedan University of Medical Science and Health Service - School of Medicine - Department of Gynecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 310-313 (7 ref.)
Keywords: Folic Acid-therapeutic use; Folic Acid-administration and dosage; Homocysteine-blood; Postmenopause;
Hormone Replacement Therapy
Abstract: This study was designed to evaluate the effect of hormone replacement therapy [HRT] and folic acid
supplementation on Homocysteine [Hcy] level in postmenopausal women. This is a randomized clinical trial conducted
on 66 postmenopausal women [menopause at least for 2 years] attending Hamedan outpatient Fatemieh teaching
hospital. Since March 2006 till April 2007. The patients were randomly divided into four groups. Before studying plasma
level of Albumin, total protein, folate, fasting level of plasma Hcy was measured. The patients of first group received
folic acid 5mg daily. In the second group of patients took oral conjugated estrogen 0/625mg and medroxy progesterone
acetate 2/5 mg daily. In third group the patients received combination of folic acid and HRT and placebo in fourth
group. Fasting plasma level of Hcy was measured four weeks later. Plasma level of Hcy was significantly decreased in
group1, 2 and 3 [P<0/05] after treatment. There was significant difference between group 1, 3 [p=0/026] and 1, 4
[P=0/005] for plasma level of Hcy. HRT and folic acid therapy can reduce plasma Hcy. Combination of both HRT and
folic acid supplementation is more effective than HRT or folic acid alone in reduction of hyperhomocysteinemia.
Horner Syndrome
diagnosis
Horner's syndrome as a co-presentation of tuberculous retropharyngeal abscess.
Raza, Syed Nusrat; Rabat, Z.M.
E-mail:[email protected]
Combined Military Hospital - Department of ENT
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 279-281 (10 ref.)
Keywords: Retropharyngeal Abscess-diagnosis; Retropharyngeal Abscess-microbiology; Tuberculoma-diagnosis
Abstract: Tuberculosis is a disease known to affect any part of the body and to present in many interesting forms. A
case of tuberculous retropharyngeal abscess is described here presenting with odynophagia and Horner's syndrome.
Horner's syndrome as a presenting feature of tuberculous retropharyngeal abscess has never been reported in
Pakistan.
40
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Subject Index
Humeral Fractures
surgery
Comparison of shoulder function, radial nerve palsy and infection after nailing versus plating in
humeral shaft fractures.
Khan, Aizaz Saleem; Afzal, Waseem; Anwar, Adnan
E-mail:[email protected]
Combined Military Hospital - Department of Orthopaedic
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 253-257 (21 ref.)
Keywords: Fracture Fixation-methods; Fracture Fixation-adverse effects; Fracture Fixation, Intramedullary; Bone
Plates; Shoulder; Radial Neuropathy; Wound Infection; Treatment Outcome
Abstract: To compare shoulder function, radial nerve palsy and infection after interlocking nailing with plating of
fractures of shaft of humerus during 30 weeks of follow-up. Experimental study. Orthopaedic Wards of Combined
Military Hospital, Rawalpindi, from November 2006 to November 2008. Two groups of 30 patients each were inducted.
Group A [n=30] was treated with intramedullary interlocking nailing while Group B [n=30] underwent plating with
dynamic compression plate [DCP]. Shoulder function using ASES score, radial nerve palsy and infection were
observed for 30 weeks. In group A, 11 patients had severe or moderate shoulder dysfunction [ASES score below 39],
out of whom 8 [72%] were above 50 years. This age related disability was significant [p=0.003]. Transient palsy was
observed in 3 patients [10%] and mild wound infection in 2 [6%], which was not associated with age or open fracture.
In group B, only 1 patient had severe shoulder dysfunction, the difference was statistically significant between the two
groups [p=0.001], especially in patients above 50 years of age. There was no statistical difference in infection and
palsy rates between the two groups. Although nailing and plating are effective treatments for fractures of shaft of
humerus, ante-grade nailing may not be suitable in elderly patients, as it can cause significant shoulder dysfunction.
Hydroxyurea
therapeutic use
Hydroxyurea can reduce or eliminate transfusion requirements in children with major and
intermediate thalassemia.
Hashemi, Azamsadat; Abrjshamkar, Mahboobeh; Jenabzade, Ali Reza; Eslami, Ziae
E-mail:[email protected]
YAZD Shahid Sadougi University - Department of pediatric hematology and oncology
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 147-150 (23 ref.)
Keywords: beta-Thalassemia-drug therapy; Blood Transfusion; Ferritins-blood
Abstract: Hydroxyurea [HU] is a well known chemotherapeutic agent that has been used largely for various
myeloproliferative diseases over the past 20 years. In beta-thalassemia, the effect of HU is much less clear and
remains controversial. This study was undertaken to describe the hematologic and clinical responses of thalassemia
major and intermediate patients to HU treatment during 2 years. Seventy one major and twenty transfusion-dependent
intermediate thalassemia participants were selected among 150 beta-thalassemia patients. All patients underwent
laboratory tests, and the state of energy, social activity, tolerance, and mood were recorded in the beginning of the
study. Echocardiography was carried out before and during treatment with HU. All patients were treated with HU; the
initial dose was 10-15mg/kg/day given once a day. All the patients tolerated HU well and showed a dramatic response
to the drug. Nine of 20 intermediate and 8 of 71 major patients became completely transfusion free. In 6 intermediate
and 15 major patients, transfusion interval prolonged more than 50%. After treatment, 95% of intermediate and 81% of
major patients described an increase in social activity. HU therapy was also associated with a marked decrease in
serum ferritin level in major thalassemia patients. HU may be administered in thalassemia major and intermediate
patients to minimize or obviate the need for regular transfusion and concomitant iron overload. HU therapy appears to
be safe and effective when administrated in thalassemia patients.
41
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Subject Index
Hyperparathyroidism
diagnosis
Severe hyperparathyroidism versus parathyroid carcinoma: a clinical dilemma.
Al Fadhli, Mariam; Doi, Suhail A.R.; Muttikkal, Thomas; Al Sumait, Basel
E-mail:[email protected]
Mubarak Al-Kabeer Teaching Hospital - Department of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 94-100 (25 ref.)
Keywords: Parathyroid Neoplasms-diagnosis; Parathyroid Neoplasms-complications; Parathyroid Neoplasmssurgery
Abstract: No clinical or laboratory data allow a preoperative diagnosis of parathyroid carcinoma and only
occasionally does a definitive finding differentiate an adenoma from a carcinoma. We present a case of primary
hyperparathyroidism presenting with severe elevation of parathyroid hormone and serum calcium as well as
complications. We go on to discuss the case in the light of a literature review. The severity of the elevation of the
parathyroid hormone, other biochemical alterations, the presence of skeletal and renal complications and of a neck
mass should alert the clinician to a possible parathyroid carcinoma. Radical surgery is the only effective therapy for
parathyroid carcinoma, and should always be performed if a preoperative suspicion is entertained.
Hyperprolactinemia
drug therapy
Comparative effects of bromocriptine and cabergoline on serum prolactin levels, liver and
kidney function tests in hyperprolactinemic women.
Mahmood, Isam Hamo; Al Husaynei, Ahmed Jasim; Mohamad, Shatha Hani
E-mail:[email protected]
College of Medicine - Department of Pharmacology
Pakistan Journal of Medical Sciences 2010; 26 (2): 255-260 (22 ref.)
Keywords: Bromocriptine-therapeutic use; Ergolines-therapeutic use; Prolactin-drug effects; Kidney Function Tests;
Liver Function Tests; Treatment Outcome
Abstract: To compare the effects of cabergoline and bromocriptine on serum prolactin levels and liver and renal
functions in hyperprolactinemic women. This study involved one hundred women, who had symptoms of
hyperprolactinemia and elevated serum prolactin concentration. They were divided into two groups of 50 women. The
first group received 0.5 mg of cabergoline weekly and the second group received bromocriptine up to a maximum of
2.5 mg twice daily. Serum prolactin, total bilirubin, serum alkaline phosphatase activity, AST activity, ALT activity,
serum creatinine and serum urea concentrations and creatinine clearance were determined at baseline and at 8 week
interval [at the end of the trial]. The efficacy of treatment was assessed with the regular menstrual cycle, absence of
galactorrhea, oligomenorrhea and normalization of serum prolactin levels. Normalization of serum prolactin level was
achieved in 28 of 50 [56%] women taking bromocriptine and in 40 of 50 [80%] women taking cabergoline. Cabergoline
group showed a higher percent of improvement of the symptoms of hyperprolactinemia. Figures of 83.33% for
amenorrhea, 71.4% for galactorrhea and 95.45% for oligomenorrhea have been noted with cabergoline versus 55.5%,
33.33% and 72%, respectively for bromocriptine. Sixty six percent of the women taking bromocriptine were reported to
have adverse effects as compared with 30% of those taking cabergoline therapy. No significant adverse effects on liver
and kidney functions have been reported in the study. The present study demonstrated that both bromocriptine and
cabergoline are effective in the treatment of hyperprolactinemia but cabergoline has the advantage over bromocriptine
in terms of both efficacy and tolerability. Therefore it is preferred in the treatment of women with hyperprolactinemia.
However, both drugs showed no abnormality in liver function as well as kidney function tests.
Hypertension, Renovascular
complications
Renovascular disease and cognitive impairment in elderly: a novel risk maker.
Gomaa, Sekina A.; Kotb, Hesham T.; Mohamed, Azza Hassan; El Sawy, Mohamed M.; Awadalla, Amira A.
Alexandria University - Faculty of Medicine - Department of Internal
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 697-712 (53 ref.)
42
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Subject Index
Keywords: Cognition Disorders; C-Reactive Protein-blood; Intercellular Adhesion Molecule-1-blood; Carotid Arteriesultrasonography; Renal Artery-ultrasonography; Ultrasonography, Doppler, Color; Glomerular Filtration Rate; Aged;
Risk Factors
Abstract: Renal artery stenosis is most commonly due to either fibromuscular dysplasia or atherosclerosis.
Atherosclerosis accounts for 90 percent of cases of renal-artery stenosis. Renal-artery stenosis may occur alone
[isolated anatomical renal-artery stenosis] or in association with hypertension, renal insufficiency [ischemic
nephropathy], or both. The aim of the present work was to study the role of renovascular disease as a novel risk
marker of cognitive impairment in elderly. The study included 80 patients divided into 4 groups: Group 1: 20 cases of
elderly patients above 65 years and suffering from grade 2 or 3 CKD. Group II: 20 cases aged 20-40 years and
suffering from grade 2 or 3 CKD. Group III: 20 healthy controls aged above 65 years. Group IV: 20 healthy controls
aged 20-40. They had been evaluated for their: Clinical condition, including physical examination and history taking,
ECG, BMI estimation, MMMS examination, Routine investigation including: complete blood picture with differential
counting, bleeding and coagulation time, liver functions tests, lipid profile, fasting and post-prandial plasma glucose,
renal function tests, complete urine analysis, 24-hours proteins in urine, assessment of glomerular filtration rate [GFR]
by MDRD and creatinine clearance and in addition specific laboratory investigations were done including: Serum CRP
using turbidimetry, Microalbuminurea using turbidimetry, v-WF Ag by ELISA, s-ICAM. By ELISA and Duplex study was
performed on carotid and renal arteries. The results of the present study showed that there was a significant increase
in the BMI in groups land II in comparison to group III which was higher than group IV. The MMMS test was
significantly lower in group I in comparison to groups II and III which were in turn significantly lower than group IV.
Hemoglobin was significantly lower in groups I and II than group III and IV. Platelets count was significantly lower in
groups I and II than group III which was also significantly lower than group IV. Creatinine clearance was significantly
lower in groups I and II than in groups III and IV vWF levels were significantly lower in groups land II than in groups III
and IV s.ICAM I was significantly higher in groups I and II compared to groups Ill and IV. CRP was significantly
increased in groups I and II in comparison to groups III and IV Carotid plaque score was significantly higher in group I
than group II which was higher than groups III. Resistive index was significantly lower in groups land II than in groups
III and IV Acceleration index was significantly lower in groups I and II than in groups III and IV. A significant positive
correlation was found between age and urinary albumin, CRP, and s.ICAM. A significant negative correlation between
age and cereatinine clearance and MDRD in groups I, II and III. Reno vascular disease is common in elderly and the
most important cause is atherosclerosis in this group of patients. There are many risk factors for cognitive impairment
in patients suffering from renovascular disease and most of them are correctable. Renovascular disease can be
considered as a novel risk factor of cognitive impairment through many interacting mechanisms.
Ibuprofen
chemistry
Dissolution of ibuprofen from spray dried and spray chilled particles.
Elkordy, Amal A.; Essa, Ebtessam A.
E-mail:[email protected]
University of Sunderland - Department of Pharmacy
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 284-290 (22 ref.)
Keywords: Microscopy, Electron, Scanning; Solubility; Calorimetry, Differential Scanning; Spectroscopy, Fourier
Transform Infrared
Abstract: The formulation of hydrophobic drugs for oral drug delivery is challenging due to poor solubility, poor
dissolution and poor wetting of these drugs. Consequently, the aim of this study was to improve the dissolution of a
model poorly water soluble drug, ibuprofen. Microparticles containing ibuprofen were produced by spray drying and
spray chilling technology in the absence/presence of a hydrophilic surfactant. Poloxamer 127, tri-block copolymer, was
chosen as the hydrophilic surfactant to improve drug particle wettability and hence the dissolution rate. The prepared
formulations were evaluated for in vitro dissolution and intrinsic solubility. In addition, the produced drug particles were
characterised by scanning electron microscopy [SEM], differential scanning calorimeter [DSC] and Fourier transform
infrared spectroscopy [FT-IR]. SEM revealed changes in the surface morphology of processed ibuprofen, suggesting
the effective formation of the drug particles. DSC data showed shifting of the melting peak of the drug towards lower
melting temperature in the prepared particles, indicating the possibility of drug /polymer interaction. The results of the
dissolution studies of spray dried ibuprofen and spray dried ibuprofen/Poloxamer 127 particles showed significantly
[P<0.05] increased percentage drug release compared to control [ibuprofen raw material]. For spray chilling, the
prepared particles did not improve the dissolution of the drug, the dissolution was even less than that of the control.
DSC and FT-IR results demonstrated that spray drying reduced drug crystallinity, but for spray chilled particles there
was evidence of polymorphic changes in the drug with and without the surfactant. Consequently, it is believed that
spray drying of ibuprofen is a useful tool to improve wettability, solubility and hence the dissolution behaviour of poorly
water soluble drugs, in contrast to spray chilling technique.
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Infection Control
Status of hospital infection control measures at seven major tertiary care hospitals of northern
Punjab.
Ikram, Aamer; Shah, Sayed Ibrar Hussain; Naseem, Sajida; Absar, Syeda Fatima; Ullah, Safi; Ambreen, Tahira;
Sabee, M. S.M.; Niazi, Saifullah Khan
E-mail:[email protected]
Armed Forces Institute of Pathology - Department of Microbiology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 266-270 (20 ref.)
Keywords: Hospitals; Health Surveys; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Cross Infection
Abstract: To determine the availability and implementation of various hospital infection control measures at tertiary
care hospitals. Survery. National Institute of Science and Technology, Islamabad, from June through August 2008.
Seven tertiary care very busy hospitals were selected; one from Islamabad, 5 from Rawalpindi, and one from Lahore. A
detailed proforma was designed addressing all the issues pertaining to hospital infection control measures. Air
sampling was done and growth yielded was identified by standard methods. Analyses revealed that all of the hospitals
had an Infection Control Committee. Microbiological diagnostic facilities were adequate at all the hospitals and overall
microorganism yield was very high. Antibiotic policy was claimed by most, not available on ground. Majority of the
operation theatres were without proper air flow system and autoclaves were not being regularly monitored. There was
no proper disposal for sharps and needles. Incineration was not the usual mode for infectious waste. The results of the
present study imply availability of proper hospital infection control policies with need of strict implementation of such
measures.
Influenza A virus, H1N1 Subtype
Are patients with malignancy more prone to swine flu complications? current status and future
strategic plans.
Sabayarr, Behnam; Lankarani, Kamran Bagheri; Vaghefikia, Azadeh
Shiraz University of Medical Sciences - School of Medicine - Health Policy Research Center
MEJC - Middle East Journal of Cancer 2010; 1 (1): 37-39 (11 ref.)
Keywords: Influenza, Human-complications; Neoplasms-complications; Risk Assessment; Vaccination
Swine flu: a fact or manufactured panic attack.
Meo, Sultan Ayoub; Imran, Muhammad Babar
E-mail:[email protected]
King Saud University - King Khalid University Hospital - Department of Physiology
Pakistan Journal of Medical Sciences 2010; 26 (2): 497-498 (9 ref.)
Keywords: World Health Organization; Disease Outbreake; Correspondence as Topic
Understanding the influenza A H1N1 2009 pandemic.
Al Muharrmi, Zakariya
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Microbiology and Immunology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 187-195 (73 ref.)
Keywords: Disease Outbreaks; Polymerase Chain Reaction; Influenza Vaccines; Influenza, Human-diagnosis;
Influenza, Human-mortality; Influenza, Human-therapy
Abstract: A new strain of Influenza A virus, with quadruple segment translocation in its RNA, caused an outbreak of
human infection in April 2009 in USA and Mexico. It was classified as Influenza A H1N1 2009. The genetic material
originates from three different species: human, avian and swine. By June 2009, the World Health Organization [WHO]
had classified this strain as a pandemic virus, making it the first pandemic in 40 years. Influenza A H1N1 2009 is
transmitted by respiratory droplets; the transmissibility of this strain is higher than other influenza strains which made
infection control difficult. The majority of cases of H1N1 2009 were mild and self limiting, but some people developed
complications and others died. Most laboratory tests are insensitive except the polymerase chain reaction [PCR] which
is expensive and labour intensive. The Influenza A H1N1 2009 virus is sensitive to neuraminidase inhibitors
[oseltamivir and zanamivir], but some isolates resistant to oseltamivir have been reported. A vaccine against the new
pandemic strain was available by mid-September 2009 with very good immunogenicity and safety profile. Surveillance
is very important at all stages of any pandemic to detect and monitor the trend of viral infections and to prevent the
occurrence of future pandemics. The aim of this review is to understand pandemic influenza viruses, and what
strategies can be used for surveillance, mitigation and control.
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Subject Index
Injections
Assessment of injection practices in public sector expanded programme of immunization clinics
in Karachi.
Habibullah, Sultana; Afsar, Salahuddin
E-mail:[email protected]
Dow Medical College - Pakistan Medical Research Council Research Centre
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 1-4 (16 ref.)
Keywords: Safety Management; Medical Waste Disposal; Immunization Programs; Public Sector; Health Surveys;
Cross-Sectional Studies; Questionnaires
Abstract: A safe injection is defined as one that does not harm the receipent, expose the health worker to avoidable
risk or result in waste that is harmful to others. To assess injection practices in Public Sector Expanded Programme of
Immunization [EPI] clinics in three urban towns of Karachi and see if these clinics meet the necessary requirement for
staff competence, supply of vaccines, injection equipment and their disposal. This was a health centre based crosssectional survey conducted in 49 Public Sector EPI clinics from June 2008 to March 2009. These clinics were selected
using random table from three urban towns i.e. Saddar, Lyari and Jamshed town of Karachi. Variables of the study
were socio-demographic characteristics of the vaccinators including their training qualifications, staff competence,
information regarding supply of vaccines, injection equipment, puncture proof safety boxes, maintenance of cold chain
and vaccination/medical waste disposal. WHO tool for the assessment of injection safety was used as a questionnaire
for the collection of data and it was analyzed on computer package SPSS version 11. Data showed that 35 [71%]
vaccinators were males and of the total, 38 [78%] vaccinators were less than 30 years of age, 45 [92%] were trained
dispensers but also trained for vaccinations and 4 [8%] staff nurses. It was observed that in all clinics disposable
syringes were used for BCG and AD syringes were used for DPT, Measles and Hepatitis vaccination. Adequate
amount of vaccines, injection equipment and puncture proof safety boxes were available, cold chain for the
preservation of vaccines was well maintained, used syringes/needles were not re-used, families did not bring their own
syringes for vaccination. Recapping of used syringes was observed in 20% clinics, skin barrier [piece of gauze under
the thumb] while breaking vaccine bottles was not practiced in any EPI clinic. All used syringes and needles were
thrown in puncture proof safety boxes. There was no history of needle prick injuries among vaccinators. Policy
Document for safe injection practice and waste disposal was not found in any EPI clinic and the staff was ignorant
about it. The study concludes that in all 49 EPI clinics, injection practice was safe except its method of waste disposal,
sufficient amount of vaccines, injection equipment, and puncture proof safety boxes were available and staffs of these
clinics were well trained. The policy document for safe disposal of sharp waste/vaccination waste should be available
at all clinics and hospitals and staff should be trained for its use.
Interferon Alfa-2a
therapeutic use
Safety and efficacy of pegylated interferon alfa-2a for the treatment of hepatitis c in patients with
major thalassemia.
Alavian, Seyed Moayed; Abolghasemi, Hassan; Miri, Seyyed Mohammad; Keshvari, Maryam; Elizee, Pegah Karimi;
Behnava, Bita; Tabatabaei, Seyed Vahid; Hajibeigi, Bashir; Lankarani, Kamran Bagheri
E-mail: [email protected] Com
Grand floor of Baqiyatallah Hospital - Baqiyatallah Research Center for Gastroenterology and Liver Diseases
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 129-137 (24 ref.)
Keywords: Polyethylene Glycols; Hepatitis C-drug therapy; beta-Thalassemia; Cohort Studies; Treatment Outcome;
Prospective Studies
Abstract: Hepatitis C virus [HCV] infection is the most common transfusion transmitted disease in poly-transfused
patients worldwide. In this study we aimed to evaluate the effects of pegylated interferon alfa-2a [PEG-IFN A-2a] in
reducing serum ALT and eradicating serum hepatitis C virus [HCV] RNA in HCV infected polytransfused thalassemic
patients. A cohort of 51 HCV-RNA positive thalassemic patients were enrolled to our study and received 180 u,g PEGIFN A-2a once-weekly for 48 weeks. The primary end point was sustained virological response [SVR]. The secondary
outcome was normalization of ALT. Patient safety was assured by monthly, and if needed, weekly laboratory
assessment and visits. Of 52 patients, 42 participants completed the treatment schedule. A sustained virological
response [SVR] was attained in 22/51 [43%] cases. Among non-responders or relapsers to previous HCV antiviral
therapy, 9/27 [33%] attained an SVR. Five patients died during treatment and 3 subjects discontinued the therapy
because of adverse effects. Adverse events were generally mild, and laboratory abnormalities were rare. A course of
48-week PEG-IFN A-2a monotherapy is effective in eradicating HCV-RNA during treatment. But about one third of
thalassemic patients would relapse within 6 months of treatment schedule completion, in whom combination therapy is
needed.
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Intervertebral Disk Displacement
therapy
Complementary-alternative medicine used by patients with disc herniation.
Kiyak, Emine; Citlik, Seyhan
E-mail:[email protected]
Ataturk University - School of Nursing - Department of Internal Diseases Nursing
Pakistan Journal of Medical Sciences 2010; 26 (2): 358-363 (19 ref.)
Keywords: Complementary Therapies; Socioeconomic Factors
Abstract: The study aimed at determining the extent of use of complementary-alternative medicine [CAM] various
CAM methods used, and factors influencing CAM application by patients with disc herniation. The subjects of this
descriptive study consisted of 134 patients with disc herniation attending the physical therapy and rehabilitation
outpatient clinic of a hospital in Erzurum, Turkey, between January and June 2008. The data were analyzed using Chisquare test based on mean and percentages calculated. While most patients preferred CAM use [71.6%] for treatment
of disc herniation disease, some did not [28.4%]. Types of CAM used by the patients varied: 67.7%, herbal medicine;
63.5%, wool belt; 34.4%, hot application; 20.8%, plaster; 14.6%, Turkish baths and/or hot springs; 13.5%, fish and/or
fish oil; 9.4%, spinal manipulation; 6.3%, cupping therapy; 6.3%, salt; 5.3%, massage; 3.1%, corset; 2.1%, plastic bag
and soap treatment. No differences were identified between the socio-demographic and disease characteristics of both
groups of patients regardless of CAM use [P>0.05]. Study showed that patients with disc herniation had higher rates of
CAM use [71.6%]. No differences were determined between the socio-demographic and disease characteristics of both
groups of patients regardless of CAM use. Thus, nurse professionals should train patients about effective and
appropriate application of CAM.
Intestinal Diseases
diagnosis
Role of multi-row detector CT enterography in evaluation of small bowel disorders.
Gamal Eldin, Omneya Ahmed; Eid, Mohamed; Afifi, Mohamed Tamer; Fathi, Alaa Mohamed; Saleh, Tarek Rashad
Alexandria University - Faculty of Medicine - Department of Radiodiagnosis
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 739-753 (49 ref.)
Keywords: Tomography, X-Ray Computed; Intestine, Small-physiopatliology
Abstract: Imaging diagnosis of small bowel diseases has long been technically challenging. Imaging techniques
included plain radiography, contrast studies, computed tomography [CT], magnetic resonance imaging [MRI],
sonography, scintigraphy and angiography. Multi-row detector CT [MDCT] enterography is a new technique that
improved depiction and characterization of small bowel pathology. To assess the role of multi row detector computed
tomography [CT] enterography in evaluation of small bowel disorders. The study was conducted on 30 patients
suffering from known or suspected small intestinal disease and subjected to CT enterography using multi-detector row
CT and iso-osmotic mannitol as neutral enteric contrast material. CT showed symmetrical mural and mucosal changes
in 12 patients, seven of them associated with comb sign and creeping fat sign proved to be Crohn's disease and five
patients without specific features due to Crohn's, ulcerative colitis, typhoid colitis, ileitis sequel to complicated
appendicitis and typhlitis with ileitis. CT showed symmetrical thickening, grey attenuation pattern and aneurysmal
dilatation proved to be lymphoma in three patients. CT showed vascular occlusion and mural changes in two patients.
CT showed hyperattenuating lesion in two patients due to bowel wall hematoma, CT showed asymmetrical thickening
in four patients, two of them showed infiltrative mesenteric mass with calcifications and desmoplastic reaction proved
to be due to carcinoid tumour. One patient with asymmetrical thickening showed strongly enhancing lesion in the
enteric phase in the second part of duodenum proved to be periampullary carcinoma. The fourth patient with
asymmetrical thickening showed heterogeneous enhancement in the venous at distal heal loop with mesenteric
stranding, lymph adenopathy and liver deposit proved to be due to adenocarcinoma. CT showed dilated bowel loops
with transitional zone in two patients proved to be due to intestinal obstruction, There were five patients with
unremarkable CT features that were followed up without definite lesion. CT enterography with iso-osmotic mannitol is a
simple, non invasive, economic, effective method for assessing small bowel disease and can replace other imaging
modalities.
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Intubation, Intratracheal
adverse effects
An unnoticed broken sheathed metallic stylet in an endotracheal tube: a case report.
Sharma, Pradeep K.; Khan, Rashid M.; Kaul, Naresh
Khoula Hospital - Department of Anesthesia and ICU
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 126-128 (6 ref.)
Keywords: Intubation, Intracheal-instrumentation; Foreign Bodies
Abstract: We report a 58-years old patient, who underwent surgery for a fracture to the neck of the femur. Tracheal
intubation was performed with the aid of a stylet; however, 15 minutes later, it was brought to the notice of the
attending anesthesiologist that a broken piece of stylet had been left inside the lumen of the endotracheal tube. Prior to
this, there was no evidence of a foreign body in the endotracheal tube or tracheobronchial tree. The broken piece of
stylet was successfully retrieved with the help of a Kocher's forceps.
Iron
therapeutic use
Better results obtained by daily supplementation of iron drops in toddlers with iron deficiency
anemia in Iran.
Shahriari, Mahdi; Tootoonchi, Hassan
E-mail:[email protected]
Shiraz University of Medical Sciences - School of Health - Hematology and Oncology Ward, Department of Pediatrics
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 159-165 (8 ref.)
Keywords: Anemia, Iron-Deficiency-drug therapy; Treatment Outcome; Prospective Studies; Questionnaires
Abstract: The [Iron Supplementation Project] for anemic toddlers in Iran has not been subject to scientific studies
yet. Since daily consumption of iron drops by children could bring about physical and mental problems, the aim of this
study was to determine whether weekly doses of iron drops would also improve the iron status of children significantly.
We determined the iron status of 12 to 21-month-old anemic toddlers receiving iron drops [ferrous sulfate] daily
referred to health care centers in Shiraz. One hundred and four children were divided into two groups; one group
receiving iron drops [1 mg/kg] daily as before, and the other group receiving iron drops weekly [3 mg/kg]. After three
months children showed a significant increase in hemoglobin [Hb], mean corpuscular hemoglobin [MCH], and mean
cellular hemoglobin concentration [MCHC] levels. Although weekly supplementation led to a significant increase in Hb
levels, daily supplementation had a significantly greater effect than weekly supplementation on the levels of mean
corpuscular volume [MCV] and MCHC. We generally conclude that weekly iron supplementation is not suitable for
anemic children.
Kidney Neoplasms
diagnosis
Small incidental renal masses in adults: review of the literature.
Al Marhoon, Mohammed S.
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Surgery
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 196-202 (33 ref.)
Keywords: Incidental Findings; Kidney Neoplasms-therapy; Biopsy; Review Literature as Topic; Adult; Carcinoma,
Renal Cell
Abstract: Incidental renal tumours are becoming an important clinical problem that many physicians will need to deal
with. A good knowledge of the nature of these tumours and how to manage them is therefore needed. The aim of this
paper is to review the literature about incidental renal tumours in adults. Many incidentally discovered small renal
tumours [<4 cm] are benign and of low stage, grade and progression potential. The preferred management in young fit
patients is open or laparoscopic nephron-sparing surgery. Treatment alternatives include needle-ablative therapies and
surveillance in elderly unfit patients. Tumour renal biopsy is encouraged prior to needle-ablative therapy and
surveillance. Awareness about incidental renal masses and their management is essential for treating doctors.
47
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Subject Index
Laryngeal Neoplasms
diagnosis
Stridor caused by a rare laryngeal tumour.
Khan, Muhammad Irshad; Aldhawi, Zaid Muhammad; Almaghrabi, Lamia Hasan
E-mail:[email protected]
Riyadh Medical Complex - Department of ENT
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 276-278 (10 ref.)
Keywords: Laryngeal Neoplasms-pathology; Paraganglioma, Extra-Adrenal; Laryngeal Neoplasms-surgery
Abstract: This report describes stridor caused by a rare laryngeal tumour. The patient had presented to ENT with a
midline neck-mass and stridor of acute onset and diagnosed radiologically as a mass in the right lobe of thyroid gland
in continuity with enhancing polypoidal mass in trachea at the same level. Total thyroidectomy along with the resection
of the mass and tracheal ring was performed, trachea being anastomosed primarily. Histopathology reported it as a
paraganglioma of the larynx. The patient has been followed-up for 5 years with no clinical or radiological recurrence of
the tumour.
Laryngoscopy
Anatomical factors of anticipated prolonged laryngoscopy.
Ahmad, Merhij
E-mail:[email protected]
Department of Anesthesiology and Intensive Care
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 38-41 (10 ref.)
Keywords: Larynx-anatomy and histology; Risk Factors; Prospective Studies; Tongue
Abstract: To evaluate the impact of some anatomical factors on the frequency of anticipated prolonged
laryngoscopy. Our investigation included 504 adult patients of both sexes, aged 23-71 years, ASA I-II, scheduled for
various elective surgical procedures at Prince Rashed military hospital during the period January 2008 till December
2008, under general endotracheal controlled anesthesia. Frequency of prolonged laryngoscopy was determined in
relation to some anatomical factors. Total frequency of prolonged laryngoscopy [>15 seconds] was 13.3% [Group II,
n=67 patients] .There were no significant discrepancies regarding demographic data in this group. Group I [n=437]
included patients with decreased laryngoscopy time [<15 seconds]. p-value was more significant [<0.05] regarding the
following anatomical risk factors: mouth opening less than 5 cm, thyromental distance less than 6.5 cm and
sternomental distance less than 12.5 cm. The presence of at least three anatomical risk factors in the same patient
could anticipate prolonged laryngoscopy and hence disturbance of ventilation.
Leishmaniasis, Visceral
congenital
Congenital visceral leishmaniasis.
Haque, Md. Azizul; Ekram, A.R.M. Saifuddin; Sharmin, Laila Shamima; Belaluddin, Md.; Salam, M.A.
E-mail:[email protected]
Rajshahi Medical College - Department of Medicine
Pakistan Journal of Medical Sciences 2010; 26 (2): 485487 (15 ref.)
Keywords: Leishmaniasis, Visceral-diagnosis; Leishmania donovani
Abstract: Visceral leishmaniasis [kala-azar] is caused by the protozoan parasite Leishmania donovani and
transmitted by the bite of infected sand fly Phlebotomus argentipes. Only a few cases of congenital transmission have
been reported. We are reporting a 15 days old baby with congenital visceral leishmaniasis and then the literature is
reviewed.
Lenses, Intraocular
Intra-ocular lens power calculation in patients with high axial myopia before cataract surgery.
El Nafees, Raouf; Moawad, Ashraf; Kishk, Hanem; Gaafar, Walid
Mansoura University - Faculty of Medicine
Saudi Journal of Ophthalmology 2010; 24 (3): 77-80 (19 ref.)
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Subject Index
Keywords: Myopia; Cataract Extraction; Prospective Studies
Abstract: To evaluate the accuracy of different formulas used for IOL power calculation in patients with high axial
myopia undergoing cataract surgery. A prospective clinical study was carried out on 53 eyes of 51 patients with an
axial length from 25.5 to 31.4 mm including 21 males [41.2%] and 30 females [58.8%]. Calculation of the IOL power to
be implanted was done by three available IOL power formulas; Haigis formula, SRK/T formula, and Holladay I formula.
The mean error [ME] was calculated from the difference between the formula predicted refractive error and the actual
post operative refractive error. There was no statistically significant difference between the mean error of the three
formulas used in the overall performance or in the axial length subcategories. SRK/T formula caused the smallest
mean error, [+0.17 D]. Haigis formula showed a higher ME [+0.21 D] and Holladay formula caused a myopic
postoperative refractive error [+0.20 D]. The calculation of IOL power in patients with high axial myopia using the third
or the fourth generation formulas help in improvement of the accuracy of the calculation and decreasing the post
operative refractive error. SRK/T formula showed the lowest mean error, however, there was not statistically significant
difference between the three formulas used, neither in the overall performance, nor in axial length subcategories.
Leukemia, Lymphoid
epidemiology
Prevalence of human T-cell leukemia virus [HTL V-I] in acute lymphatic leukemia and
lymphomas in Alexandria.
El Saygh, Mervat; El Ghandour, Ashraf
Alexandria University - Faculty of medicine - Department of Microbiology and Internal Medicine [Hematology]
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 713-720 (16 ref.)
Keywords: Lymphoma; Deltaretrovirus; Prevalence
Abstract: The aim of this study was to find the incidence of human T. Cell leukemia virus [HTLV-I] in acute lymphatic
leukemia and lymphomas in Alexandria. 100 cases of acute lymphatic leukemia and lymphoma attended the Main
University Hospital, out patient clinics and internal medicine department-150 Control of other types of leukemias,
cancer and normal subjects attending also the out patient clinics and internal medicine department. The patients and
controls were subjected to the following: Clinical examination, White cell count total and differential, Bone marrow
Aspiration, Lactic acid dehydrogenase enzymens, Serum calcium, Erythrocytic Sedmentation Rate [E.S.R.], C-reactive
protein [C.R.F.], Anti HTLV-1 antibodies using SERODI-HTLV-1 [passive particle agglutination test manufactured by
FUJIREBIO Inc. Tokyo-Japan]. HTLV-I Ab was positive in 14% in cases of acute lymphatic leukemia and lymphoma.
While, it was positive in the control group compared to Normal subjects and other types of leukemia and cancer [3.3%].
It was found that HTLV-1 virus in acute lymphatic leukemia is less than in other endemic areas. Trials for immunization
are urgent. Blood blanks examination for the virus is essential, where it is transmitted by 1] blood 2] mother to child
[breast feeding] 15 and transpiacental, 3] Sexually transmitted disease [STD].
Leukoeytes
physiology
Leucocytes show improvement growth on PHA polymer surface.
Hassan, Mohamad A.; Amara, Amro A.; Abuelhamd, Ashraf T.; Haroun, Bakry M.
Mubarak City for Scientific Research and Technology Applications - Genetic Engineering and Biotechnology Research
Institute - Protein Research Department
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 332-336 (28 ref.)
Keywords: Polyhydroxyalkansates-pharmacology; Polyhydroxyalkansates-metabolism; Cell Proliferation; Cells,
Cultured; Hemolysis-drug effects
Abstract: Polyhydroxyalkanoate [PHA] from one fermentation process shows diverse physical properties when
extracted using different methods. Pseudomonas aeruginosa strain has been previously isolated from the Egyptian
ecosystem was cultivated on olive oil as a carbon source under PHA accumulation conditions. PHA was extracted
using four different extraction methods and the polymer give different biological properties. Leucocytes grown in
different rate on each preparation. RBCs haemolysis test was used to determine the polymers toxicity. PHA isolated
directly with chloroform give the highest leucocytes number [19.4 10 4 Cells/48 hr] and the lowest Haemolytic index
[2.28]. Bioassays used in this study are recommended for evaluating the in vitro polymer biocompatibility aiming to in
vivo application or as a cell line-supporting matrix.
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Lipoma
diagnosis
Lipoma Arborescens of the knee: report of a case with full range of motion.
Ensafdararr, Ahmad; Vosoughi, Amir Reza; Khozai, Arash; Torabi, Simin; Ensafdararr, Mohammad Reza
Shiraz University of Medical Sciences - Chamran Hospital - Research Center for Bone and Joint Diseases, Department
of Orthopedics
MEJC - Middle East Journal of Cancer 2010; 1 (1): 51-54 (10 ref.)
Keywords: Knee-pathology; Range of Motion, Articular; Synovial Membrane-pathology; Arthroscopy; Lipomapathology; Magnetic Resonance Imaging
Abstract: This report describes a rare intra-articular benign tumor, lipoma arborescens, of the knee joint in a 21 yearold female. The patient suffered from left knee joint swelling for five years with occasional pain. Swelling was soft and
boggy in the suprapatellar area. Motion of joint was complete. No abnormality was detected in any laboratory tests.
MRI showed a large soft tissue density in the suprapatellar area with high signal intensity on T[1] and T[2] weighted
images. Operative arthroscopy revealed a creamy brown hypertrophied synovium with diffuse papillary processes
characterized by villous proliferation of the synovium infiltrated by mature fat tissue, chronic inflammatory cells and
vessels as seen in the pathologic slides. Lipoma arborescens or villous lipomatous proliferation of the synovial
membrane should be distinguished from other similar lipomatoid conditions such as synovial lipoma and Hoffa disease.
Lipoma arborescens should be considered in patients with painless, slowly progressive swelling of a joint, especially
the knee.
Liver Function Tests
Liver function tests pre and post-cholecystectomy in gall bladder stone patients.
Bashi, Ahmed Yahya Dallal; Al Kataan, Mohammad Abdul Ghffoor; Al Khyatt, Muzahim Kasem
E-mail:[email protected]
Uuniversity of Mosul - College of Medicine - Department of Medical Biochemistry
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 15-21 (16 ref.)
Keywords: Cholecystectomy; Gallstones-complications; Gallstones-surgery
Abstract: To determine the changes in some liver function tests in gall stone patients before, after one week and
after one month of cholecystectomy. Sixty patients [19 males and 41 females], ages ranged from 22-79 years, were
included in this study. All of them underwent cholecystectomy in either of two hospitals [Al Zahrawae General hospital
and Ninevah Private Hospital] during a period of six months from 1st October 2004 to 31st March 2005. The following
tests were performed: total serum bilirubin, direct serum bilirubin, alanine aminotransferase activity, aspartate
aminotransferase activity, alkaline phosphatase activity, total serum protein and serum albumin. The results of the data
analyzed are presented according to the intervals at which the samples were obtained from the patients as follows:
Day of cholecystectomy, after one week of cholecystectomy, and after one month of cholecystectomy. There was a
significant reduction in total serum bilirubin, direct serum bilirubin, alanine transaminase, aspartate transaminase
activities after one month of cholecystectomy when compared to that before and after one week of operation.
Meanwhile, a significant elevation in alkaline phosphatase activity after cholecystectomy in both intervals. The
maximum elevation was after one week, and then it decreases significantly after one month of cholecystectomy when
compared to that after one week of operation. Gall stone is an important cause of significant pathological changes in
some liver profile parameters, these parameters will return toward normal after cholecystectomy. This normalization
will be increased with the time.
Mastitis
Microbiology
Influence of subclinical mastitis on some reproductive parameters in Holstein-Friesian dairy
cows.
Hussein, M.M.; El Agawany, A.A.; Khalil, A.A.Y.
Beni-Suef University - Faculty of Vet. Medicine - Department of Theriogenology
Veterinary Medical Journal 2009; 57 (1): 97-113 (75 ref.)
Keywords: Pregnancy, Animal; Reproduction
Abstract: Over a period of one year [Nov., 2007-Oct., 2008] a total of 1757 Holstein-Friesian cows belonging to a
commercial dairy farm in Giza-Egypt were included in this investigation. Somatic cell count [SCC] as a measure of
subclinical mastitis was recorded for three times in three consecutive months. Bacteriological examination was also
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done for milk sample. Reproductive data including days to first insemination, number of inseminations per conception
[S/C] and days open [DO] were individually recorded, also the percentage of cows conceived by 305 days in milking
[DIM] and percentage of culled cows for reproductive failure were recorded. The obtained data were recorded .The
animal status [parity and reproductive status] as well as the establishment and degrees of affection were also
considered. The obtained results were recorded and statistically analyzed. Results revealed that, the incidence of
subclinical mastitis was 31.75 and 23.79% of the total lactating non pregnant and lactating pregnant cows,
respectively. Among cases of subclinical mastitis, 75% were bacteriolo-gically positive. Coagulase-negative
staphylococci, Staphylococcus aureus, Streptococcus uberis and Streptococcus dysgalactiae were the prevalent
isolates. The adverse effects of subclinical mastitis on the reproductive performances in dairy herd included prolonged
days to first insemination; Days open; increased number of inseminations per conception and culling rate for infertility.
The establishment of subclinical mastitis during the interval to first insemination prolonged this stage while, the
establishment from the first insemination to the fertile one prolonged the days open and increase the number of
inseminations per conception.lt could be concluded that, subclinical mastitis was associated with unfavourable effects
on reproductive performance of dairy cows. Therefore, the appropriate management of lactating dairy cows to minimize
the incidence of mastitis should increase the profitability of dairy herds not only by improving milk quality, reducing the
use of antibiotics, reducing the amount of milk discarded, and reducing involuntary culling, but also by improving
reproductive performance.
Measles
epidemiology
Epidemiology of measles outbreaks in Qatar in 2007.
Al Kuwari, M.G.; Nozzal, Z.A.; Al Khenji, A.A.
Primary health care practice
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 186-190 (17 ref.)
Keywords: Disease Outbreaks; Retrospective Studies; Measles-Mumps-Rubella Vaccine
Abstract: While a major reduction in morbidity and mortality from measles has been achieved in Qatar since it
adopted the measles elimination programme in 1997, the country has experienced small, recurrent measles outbreaks.
The aim of this study was to determine the demographical and epidemiological characteristics of measles cases
reported to the surveillance programme in Qatar in 2007. Of 362 confirmed cases 67.7% were among children aged 114 years old and 16.9% were > 15 years. A majority of cases were unvaccinated [35.9%] or had unknown or
undocumented vaccination status [47.0%]. The high proportion of cases were among Pakistani nationals [39.5%]
followed by Qataris 927.6%]. Measles outbreaks were concentrated among the children of expatriates of Asian
ethnicity with unknown vaccination status. This highlights the importance of achieving uniformly high levels of
vaccination coverage in a community.
Measles Vaccine
immunology
Seroresponse to the second measles vaccine dose at school entry in Qassim province, Saudi
Arabia.
Khalil, M.K.M.; Nadrah, H.M.; Al Yahla, O.A.; El Ghazali, G.
E-mail:[email protected]
Ministry of Health - Medical Research Administration - Department of Communicable Diseases [Vaccinology] and
Research Development
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 191-195 (26 ref.)
Keywords: Immunization, Secondary; Immunization Schedule; Schools; Enzyme-Linked Immunosorbent Assay
Abstract: In 2001, the measles immunization schedule in Saudi Arabia was changed to 2 measles, mumps and
rubella vaccine doses at 12 months and at 6 years. In this follow-up study we evaluated the seroresponse to the
second measles dose before school entry. We recruited 138 children randomly from primary health care centres in
Qassinn; 124 children completed the study. Blood samples were collected before and 1 month after giving the second
measles dose, before the age of 6 years. There was a statistically significant increase in the geometric mean titre of
measles antibody, from 2205 m lU/mL before vaccination to 4723 mlU/mL after [P = 0.0001]. The proportion of children
with positive ELISA results increased fro++ 94.2% before vaccination to 99.2% after [P = 0.02], while the proportion
with protective level [^200 mlU/mL] increased from 97.1% before vaccination to 99.19% after [P= 0.21]. The 2-dose
measles immunization schedule can produce optimum protection at school entry if high vaccination coverage is
guaranteed.
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Medical Records
An improved record system for tracing outcome of [transferred-out] DOTS patients.
Shabbir, R.; Iqbal, M.; Anwar, E.; Qadeer, E.; Ahmed, N.
E-mail:[email protected]
King Edward Medical University - TB Research Centre
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 88-92 (12 ref.)
Keywords: Tuberculosis; Treatment Outcome; Quality Improvement
Abstract: This study in Pakistan aimed to develop an improved record-keeping mechanism for the DOTS programme
to establish the final treatment status of patients recorded as [transferred -out]. In an intervention study in 40 DOTS
diagnostics centres in Punjab province, a modification was made to the existing TB03 register. DOTS facilitators were
trained to keep proper records of patients who transferred-out and transferred-in. Among 4442 registered cases, 104
patients [2.3%] transferred out of reporting centres. Correct matching of [-out and -in] patients was achieved for 74
[71.2%] patients; the remaining 30 [28.8%] were untraced. By tracing transferred-out cases, the adjusted outcome
success rate increased in the intervention period from 89.6% to 90.9%.
Medication Errors
Medication errors in primary care in Riyadh city, Saudi Arabia.
Khoja, T.; Neyaz, Y.; Quresh, N.A.; Mogzoub, M.A.; Haycox, A.; Walley, T.
Cooperation Council for the Arab States of the Gulf
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 156-159 (22 ref.)
Keywords: Physicious, Primary Care; Primary Health Care; Cross-Sectional Studies; Drug Prescriptions
Abstract: Medication errors can cause a variety of adverse drug events but are potentially preventable. This crosssectional study analysed all medication public and 5 private primary health care clinics in Riyadh city, collected by
simple day. Prescriptions for 2463 and 2836 drugs from public and private clinics which were analysed using Neville et
al.'s classification of prescription errors. Prescribing errors were found on 990/5299 [18.7%] prescriptions. Both type B
and type C errors [major and minor nuisance] were more often associated with prescriptions from public than private
clinics. Type D errors [trivial] were significantly more likely to occur with private health sector prescriptions. Type A
errors [potentially serious] were rare [8/5299 drugs, 0.15%] and the rate did not differ significantly between the 2 health
sectors. The development of preventive strategies for avoiding prescription errors is crucial.
Medicine, Traditional
Traditional medicine: perceptions and experience of medical students from Egypt and Saudi
Arabia, a comparative study.
Makdoom, Naeem; Hanafi, Manal Ibrahim; Mohamed, Aida Mohey; Mubarak, Iman Ibrahim
Taibah University - Faculty of Medicine - Department of ENT
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 727-737 (25 ref.)
Keywords: Students, Medical; Perception; Comparative Study; Curriculum
Abstract: In view of the increasing popularity of traditional medicine [TM], it is imperative that medical students, the
health professionals of tomorrow, possess adequate knowledge on the topic. The incorporation of TM into medical
curricula is handled quite differently by different institutions and countries. To assess the knowledge, attitudes and
experience of Alexandria and Saudi medical students about TM and compare between them, and to identify their
perceptions and opinions about applicability and the importance of its integration into the medical curriculum. This is a
comparative descriptive study. A questionnaire-based cross-sectional survey was done on 489 fourth year medical
students selected randomly from Alexandria medical college and 85 fourth year students selected from Tiabah medical
college [Saudi Arabia]. Comparison between the two groups and different variables were tested using the x2-and
Mann-Whitney tests of significance, Taibah students were more aware of and believed that some of the TM modalities
are useful. The two groups of students lacked knowledge about their safety and efficacy. Taibah students were
significantly more experienced in TM than Alexandria students. Most of the students in the two groups believed that TM
should be used in conjunction with conventional medicine and that, if given adequate training, they would incorporate it
in their future medical practice. Most students in the two disciplines favored incorporation of TM into the medical
curriculum and the difference was not significant. Despite being aware of the usefulness of TM, only a few medical
students had pursued further knowledge. Therefore consideration for incorporation of TM in medical curriculum may be
helpful and necessary.
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Melatonin
administration and dosage
Effect of melatonin supplementation on plasma glucose and liver glycogen levels in rats
subjected to acute swimming exercise.
Kaya, Oktay; Kilic, Mehmet; Celik, Ilham; Baltaci, Abdulkerim Kasim; Mogulkoc, Rasim
E-mail:[email protected]
Sports Firat University - School of Physical Education
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 241-244 (15 ref.)
Keywords: Blood Glucose-analysis; Liver Glycogen-analysis; Physical Conditioning, Animal; Rats; Swimming;
Dietary Supplements
Abstract: The aim of the present study is to examine how melatonin supplementation affects plasma glucose and
liver glycogen levels in rats subjected to acute swimming exercise. Spraque-Dawley species thirty adult male rats were
allocated to 3 groups with equal number of animals: general control group which was not subjected to any procedure
[Group 1], the group subjected to a 30-minute acute swimming exercise [Group 2], and the group subjected to a 30minute acute swimming exercise after intraperitoneal [i.p.] melatonin supplementation [3 mg/kg/day] for 4 weeks
[Group 3]. Blood samples collected from the experimental animals by decapitation method were analyzed in terms of
plasma glucose, and glycogen levels were determined in liver tissue samples by histological method. The highest
plasma glucose levels were obtained in group 2 [p<0,05]. Plasma glucose levels in groups 1 and 3 were not different.
Mean liver glycogen level in group 3 was significantly higher than those in the other groups [p<0,01], while there was
no significant difference between group 1 and group 2 in terms of this parameter. Results of the study demonstrate that
melatonin supplementation can have a protective effect on liver glycogen reserves in rats subjected to acute swimming
exercise.
Meningioma
pathology
Cervical lymph node metastases from meningioma: report of two cases and treatment outcome.
Omidvari, Shapour; Nasrolahi, Hamid; Daneshbod, Yahya; Bagheri, Neda; Negahban, Shahrzad;
Mohammadianpanah, Mohammad; Ahmadloo, Niloofar; Ansari, Mansoor; Mosalaei, Ahmad
E-mail:[email protected]
Shiraz University of Medical Sciences - Nemazee Hospital - Department of Radiation Oncology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 45-49 (17 ref.)
Keywords: Lymphatic Metastasis; Treatment Outcome; Biopsy; Meningioma-drug therapy; Meningiomaradiotherapy; Immunohistochemistry
Abstract: Meningioma is usually a benign central nervous system [CNS] tumor. Metastasis is rare; however if it does
occur the most metastatic sites are the liver and lungs. Here, two cases of CNS meningioma with metastasis to
cervical lymph nodes are reported. The first case, a 48 year-old man developed cervical lymph node metastasis nine
years after primary tumor diagnosis. The second case, a 23 year-old woman with parietal lobe meningioma, developed
lymph node metastasis in the neck nine months after the diagnosis of meningioma.
Meningitis, Bacterial
cerebrospinal fluid
Predictors of bacterial meningitis in adult patients of South West Iran.
Alavi, Seyed Mohammad; Moshiri, Naser
E-mail:[email protected]
Joundishapour University of Medical Sciences - Joundishapour Infectious and Tropical Diseases Research Center
Pakistan Journal of Medical Sciences 2010; 26 (2): 341-346 (19 ref.)
Keywords: Meningitis, Bacterial-diagnosis; Cerebrospinal Fluid-chemistry; Cerebrospinal Fluid Proteins;
Retrospective Studies; Sensitivity and Specificity; Predictive Value of Tests
Abstract: To study the clinical and lab parameters in adult patients with suspected or confirmed bacterial meningitis
[BM] to find out the usefull predictors. This was a retrospective study conducted in Razi hospital, a training center
affiliated to Ahvaz Joundishapoor University of Medical Sciences in Iran. All patients with meningitis aged 18 years or
more between 2003 and 2007, with CSF pleocytosis and who had not received antibiotic treatment before lumbar
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puncture were reviewed. Among 312 patients with CSF pleocytosis, two hundred fifteen [68.9%] had BM and ninety
seven [31.1%] had aseptic meningitis [ASM]. The mean age for patients with BM was 34.7 +/- 17.7 years and for ASM
was 32.2 +/- 15.5 years [P=0.22, NS]. Sixty percent of the cases of BM and 61.2% of the cases of ASM occurred in
men [P=0.70, NS]. We identified the following predictors of BM: CSF-WBC count>100 per micro liter, CSF-glucose
level<40 mg/dl, CSF-protein level>80 mg/dl. Sensitivity, specificity, PPV, NPV of these predictors, and LR for BM are
86.5%,52.6%,80.2%, 63.7% and 104.1 for CSF-WBC count and 72.1%, 83.5%, 90.6%,57.4% and 164.2% for CSF
glucose, and 49.7%, 91.8%, 93.4%,45.2% and 104.5% for CSF protein. The CSF WBC count should not be used
alone to rule out bacterial meningitis. When it is combined with other factors such as CSF glucose and protein it helps
in decision making in patients suffering from bacterial meningitis.
Menorrhagia
therapy
Oral versus rectal misoprostol in the treatment of menorrhagia.
El Makhzangy, Ibrahim Mohamed; Hegab, Hassan Mansour
Alexandria University - Faculty of Medicine - Department of Obstetric and Gynecology
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 721-725 (20 ref.)
Keywords: Misoprostol-administration and dosage; Administration, Oral; Administration, Rectal; Comparative Study;
Treatment Outcome
Abstract: Excessive menstrual loss is a major problem. Effective medical treatments exist and its increased use will
improve patient choice and provide an alternative to surgery. Evaluation of the effects of oral and rectal misoprostol in
the treatment of excessive blood loss in cases of menorrhagia and comparing between both routes. Sixty women
complaining of regular but heavy periods [menorrhagia] were included in the study. They were divided into two equal
groups. Both groups were evaluated in two consecutive menstrual cycles. First without treatment [basal value] and the
second cycle by either rectal misoprostol tablets [three times daily for the first three days of the bleeding] or by oral
misoprostol tablets [one tablet three times daily for the first three days of the bleeding]. For both groups the estimated
menstrual blood loss [EBL] was assessed before and after treatment using subjective and objective assessment. A
highly statistical significant reduction in menstrual blood loss occurred by treatment in both groups [p=0.000]. Rectal
misoprostol produced the highest reduction in the menstrual blood loss with a percent change of 53.45%, while oral
misoprostol was less effective in reducing the menstrual blood loss with a percent change of 36.15% Both routes were
effective in improving dysmenorrhea and reducing the number of cycle days with no significant differences between
them. Both rectal and oral misoprostol are save and effective routes for reducing excessive menstrual blood loss
[menorrhagia], but rectal route is more effective.
Mental Retardation
psychology
Psychiatric disorders among mentally retarded adults in Kuwait.
Al Mutairi, Haya A.; Al Mutairi, Sara A.
Ministry of Health - Psychological Medicine Hospital - Department of Special Education Science
Bulletin of Alexandria Faculty of Medicine 2009; 45 (4): 691-696 (27 ref.)
Keywords: Adult; Prevalence; Behavioral Symptoms; Mental Health Services; Questionnaires
Abstract: Behavior disorders can be disabling for mentally retarded adults with negative consequences for the
adults, their families and paid carers. Psychiatric evaluation of adults with mentally retarded individuals remains
complex because of limitations in verbal abilities, atypical clinical presentation and challenging behavior. To determine
the prevalence of psychological disorders among mentally retarded personnel and the impact of gender, type of
adtninistered care and degree of mental retardation. The study design was a cross sectional descriptive one that was
carried out in a day care center and another full accommodation one. The target population of the study was potentially
all individuals suffering from mild or moderate degree of mental retardation aged 15-30 years in the selected facilities.
The final studied sample consisted of 160 persons. A specially designed questionnaire was prepared. It included data
about personal characteristics, degree of mental retardation and type of care facility, and a section about the presence
of psychological disorders. In this section twelve psychological disorders were identified to be studies using a
diagnostic rating scale of psychiatric disorders based on Diagnosis and Statistical Manual of Mental Disorders. Overall,
30.9% of persons with mental retardation have at least one psychiatric disorder. The most common psychological
disorder was the organic brain syndrome [15.6%]followed by autism and self-injury [7.5% for each], sleeping disorders
[6.9%] and sexual disorder [6.2%]. Psychological disorders were more commonly encountered among mentally
retarded females than males, except for obsession, without significant differences. Institutionalized mentally retarded
personnel tended to significantly suffer more from organic brain syndrome [27.6% compared with 3.8%, P<0.001], selfinjury [13.8% compared with 1.3%, P=0.005], sexual disorders [11.3% compared with 1.3%, P=0.018], schizophrenia
[13.8% compared with 0.0%, P 0.003], and autism [13.8% compared with 1.3%, p=0.005]. Only self-injury and organic
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brain syndrome were significantly associated with the severity of mental retardation. Psychiatric disorders are
frequently encountered among mentally retarded individuals in Kuwait. Guidance is required on mental health services
and staff training, including psychiatric treatment in community care and a model for inpatient services for mentally ill
persons.
Metformin
therapeutic use
Pioglitazone versus metformin in two rat models of glucose intolerance and diabetes.
Gad, Mohamed Z.; Ehssan, Noha A.; Ghiet, Mansour H.; Wahman, Lobna F.
E-mail:[email protected]
Ain Shams University - Faculty of Pharmacy - Biochemistry Department
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 305-312 (38 ref.)
Keywords: Thiazolidinediones-therapeutic use; Glucose Intolerance-drug therapy; Diabetes Mellitus, Experimental;
Hypoglycemic Agents-therapeutic use; Rats; Blood Glucose-analysis
Abstract: Insulin resistance has been implicated in the pathogenesis of type 2 diabetes. High fat diets cause insulin
resistance. Both metformin and pioglitazone are considered "insulin sensitizers" and used as antihyperglycemic agents
for type 2 diabetes treatment. The aim of this study is to Compare pioglitazone and metformin effects on carbohydrate
metabolism and insulin sensitivity in diabetic and glucose intolerant rats on high fat diet. Male albino rats were
randomized to seven groups. The 1 st group received high carbohydrate diet [control]. The 2 nd, 3 rd and 4 th groups
received high sunflower oil diets for 6 weeks and either left untreated, or given pioglitazone or metformin during the last
3 weeks. The 5 th, 6 th, and 7 th groups were made diabetic by STZ injection on day 15 of the 6 weeks-high fat diet
regimen. They were either left untreated, or given pioglitazone or metformin during the last 3 weeks. High-fat diet
induced glucose intolerance; represented by increase of serum glucose associated with increase in liver glucose-6phosphatase and decreases in liver glucose-6-phosphate dehydrogenase and glucokinase activities. No significant
differences were observed between pioglitazone and metformin. In diabetic rats, both pioglitazone and metformin
decreased elevated serum glucose by-30%. Only metformin increased hepatic glycogen, and normalized glucose-6phosphatase activity. On the other hand, pioglitazone normalized elevated renal glycogen content and increased
glucose-6-phosphate dehydrogenase activity. High sunflower oil diet impaired glucose tolerance. Pioglitazone and
metformin had comparable effects on estimates of carbohydrate metabolism and insulin sensitivity in high-fat fed rats,
but different effects in diabetic rats.
Methemoglobin
Studies of methemoglobin concentrations of three human erythrocyte genotypes [HB AA, HB
AS, and HB SS] in the presence of five anti-malarial drugs.
Chikezie, Paul C.; Monago, Comfort C.; Uwakwe, Augustine
Imo State University - Department of Biochemistry
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 151-157 (26 ref.)
Keywords: Erythrocytes-drug effects; Genotype; Antimalarials; Spectrophotometry
Abstract: Malaria remains the world's most devastating human parasitic infection. Our goal was to assess the
capacity of increasing concentrations of five antimalarial drugs [Fansidar[tm], Halfan[tm] , Quinine, Coartem[tm] and
Chloroquine phosphate] to elicit the generation of methemoglobin in three human erythrocyte genotypes [Hb AA,
HbASandHbSS]. Spectrophotometric method was used for determination of plasma methaemoglobin concentration in
the presence of 0.2 g%, 0.4 g%, 0.6 g% and 0.8 g% [w/v] of the five antimalarial drugs. The five antimalarial drugs
showed a concentration dependent variability to cause the elevation of plasma methemoglobin concentration in the
three genotypes. Specifically, Coartem[tm], exhibited the highest propensity to elevate plasma methemoglobin
concentration. However, the other four antimalarial drugs showed a statistically significant [P<0.05] but minimal effect
to cause elevation of plasma methemoglobin concentration. For instance, with Hb AS blood sample and at drug
concentration of 0.8g%, methaemoglobin concentrations [percentage] of 3.03 +/- 1.82, 2.65 +/- 0.45, 6.41 +/- 1.21, and
3.02 +/- 0.98 were obtained for halfan, quinine, coartem and chloroquine phosphate, respectively. The control value
was 2.17 +/- 1.82% of methemoglobin. The oxidative potentials of these four antimalarial drugs and their metabolites in
the red cells did not overwhelm the erythrocyte methemoglobin reducing capacity that could elicit the presentation in
vitro toxic methemoglobinemia.
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Miosis
prevention and control
Comparison of ketorolac tromethamine and prednisolone acetate in preventing surgically
induced miosis during cataract surgery.
Suleiman, Yusuf M.; Krdoghli, Najwa F.; Ahmad, Aksam J.
Tishreen University - Al Assad Hospital - Department of Ophthalmology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 57-63 (28 ref.)
Keywords: Ketorolac Tromethamine-therapeutic use; Prednisolone-therapeutic use; Cataract Extraction;
Prospective Studies
Abstract: The aim of this study was to compare the efficacy and safety of topical prednisolone acetate 1% and
topical ketorolac tromethamine 0.5% in the maintenance of pupillary mydriasis during cataract surgery. Fifty patients
were enrolled in this prospective, partially masked and randomised study. They were assigned to receive topical
treatment with either prednisolone acetate [n=25] or ketorolac tromethamine [n=25], starting 24 hours before cataract
extraction [either routine extracapsular cataract extraction or phacoemulsification]. One drop of the study medication
was instilled every 6 hours for a total of 4 drops. No epinephrine was used in the intraoperative irrigation solution. Pupil
diameter was measured three different times during surgery. To ensure participant safety, biomicroscopy,
ophthalmoscopy, intraocular pressure, adverse events and visual acuity were also monitored. The mean pupil diameter
change from the time of the pre-incision until after cortical irrigation and aspiration and lens implantation was
significantly less with ketorolac than with prednisolone [P=0.003]. Consequently, mean pupil diameter after cortical
irrigation and aspiration and lens implantation was significantly greater with ketorolac than with prednisolone
[P<0.0001]. No significant differences between groups were observed in the pupil diameter before the first incision
[P=0.244], nor after administration of a miotic agent [P=0.505]. Safety variables were comparable and no drug-related
adverse events were reported. Ketorolac tromethamine 0.5% and prednisolone acetate 1% solutions were equally well
tolerated without related adverse events, but ketorolac was better in preventing surgically induced miosis.
Misoprostol
administration and dosage
Sublingual versus oral misoprostol for induction of labour in prelabour rupture of membranes at
term.
Malik, Humaira Zaman; Khawaja, Nuzhat Parveen; Zahid, Bushra; Rehman, Rakhshanda
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 242-245 (22 ref.)
Keywords: Misoprostol-therapeutic use; Labor, Induced; Fetal Membranes, Premature Rupture; Administration,
Sublingual; Administration, Oral; Treatment Outcome; Randomized Controlled Trial as Topic
Abstract: To compare the efficacy of sublingual with oral misoprostol for induction of labour in primigravida with prelabour rupture of membranes at term. Randomized controlled trial. Department of Obstetrics and Gynaecology Unit-11,
Sir Ganga Ram Hospital, Lahore, from June 2004 to January 2006. The study included 100 primigravidas with
singleton pregnancy at term, having pre-labour rupture of membranes and unfavourable Bishop score with no
contraindication of induction of labour, vaginal delivery or misoprostol use. The cases were randomized into two equal
groups, A and B. Women in the group A were given 100 micro g of misoprostol orally at an interval of 4 hours to a
maximum of 2 doses while patients in the group B were prescribed the medicine sublingually [50 micro g, 4 hourly,
maximum of 2 doses]. Induction to delivery interval, mode of delivery and fetomaternal complications were main
outcome measures of the study. In the sublingual misoprostol group [B], 92% women delivered within 12 hours of
induction while 84% of subjects delivered in this time period in oral group [A, p < 0.05]. There was no failed induction in
either group. Regarding dosage, 64% of women delivered with single dose in group B while only 32% delivered with
single dose in group A [p < 0.05]. The frequency of vaginal delivery was 92% in group B versus 80% in group A, while
rate of caesarean section was 8% in the group B and 20% in the group A, which is statistically insignificant. No
significant fetomaternal complications were seen in both groups. The efficacy of sublingual misoprostol in the dosage
of 50 micro g was comparable to 100 micro g oral dose for the induction of labour in the primigravidas at term with prelabour rupture of membranes.
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Motor Activity
Impact of mild physical activity on the random blood sugar among yemeni diabetic patients.
Atef, Zayed A.; Al Kumaim, Mohamed; Al Ezzy, Yehia
E-mail:[email protected]
Sanaa Uuniversity - Faculty of Medicine - Department of Internal Medicine
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 9-14 (19 ref.)
Keywords: Blood Glucose; Diabetes Mellitus
Abstract: Descriptive study was carried out during the marathon of Yemeni diabetic patients as a public activity in the
World Diabetes Day [WDD] to encourage the Yemeni people and educate them about the importance of physical
activity, and to study the effect of walking as a mild physical activity on lowering blood sugar level. A total of 502
participants aged between 15 and 70 years, 85% males and 15% females, 352 diabetics; 8.32% type 1 and 26.29%
type 2. Also 150 [29%] non diabetic participants [unknown] were included. All participants subjected to analysis of
[RBS] at the beginning of marathon and at the end of it for most of them. After 4 km walking during 45 minutes we
found that there was a significant reduction in R.B.S; it was 24.44 mg/dl, 15.80 mg/dl, and 27.19 mg/dl among all
participants, type 1 and type 2 diabetic patients respectively. The significant reduction in R.B.S level after walking
means that the beneficial effect of exercise can be obtained by mild to moderate exercise, since the effect seems to
depend on overall energy expenditure rather than on intensity of exercise.
Multiple Sclerosis
The effect of urinary incontinence and sexual dysfunction on the quality of life among women
with multiple sclerosis.
Goris, Songul; Tasci, Sultan; Mirza, Meral; Ceyhan, Ozlem; Tekinsoy, Pinar; Sungur, Gonul
E-mail:[email protected]
University of Erciyes - Ataturk School of Health - Department of Medical Nursing
Pakistan Journal of Medical Sciences 2010; 26 (2): 277-281 (30 ref.)
Keywords: Urinary Incontineuce; Sexual Dysfunction, Psychological; Quality of Life; Questionnaires
Abstract: This study was conducted in order to determine the effect of urinary incontinence and sexual dysfunction
on the quality of life among women with Multiple Sclerosis [MS]. The descriptive study included 60 women with Multiple
Sclerosis [MS]. The data were collected through a questionnaire forms designed by the researchers, Arizona Sexual
Experiences Scale and Short Items Form of Health-Related Quality of Life. Chi-square, t and ANOVA test were used.
Almost half of the women had urinary incontinence problem and 63.0% did not visit the doctor. It was determined that
the urinary incontinence was higher in women, who were over 45 years old, married and had children, and diagnosed
for 6 years and more [p<0.05]. Twenty-eight point three percent [28.3%] of the MS women had sexual dysfunction. It
was determined that women with urinary incontinence had a lower quality of life and more sexual dysfunction.
Mupirocin
therapeutic use
[Does nasal decontamination reduce the incidence of infections after cardiac surgery?].
Jabbour, H.; Madi Jebara, S.; Jabbour, K.; Yazigi, A.; Haddad, F.; Hayek, G.; Yazbeck, P.; Antakly, M.C.
E-mail:[email protected]
University Hospital Center - Department of Anaesesiology
LMJ - Lebanese Medical Journal 2010; 58 (2): 65-70 (27 ref.)
Keywords: Nasal Cavity-microbiology; Thoracic Surgery; Preoperative Care; Surgical Wound Infection-prevention
and control; Prospective Studies; Treatment Outcome
Abstract: Mupirocin applied to the anterior nares four times daily usually eliminates Staphylococcus aureus,
including methicillin resistant, within 48 hours. Prophylactic intranasal mupirocin is safe, inexpensive and effective in
reducing the overall sternal wound infection after open-heart surgery. This study was designed to determine whether
decreasing nasal bacterial colonization by applying mupirocin intra nasally decreases mediastinal, sternal, pulmonary
and cutaneous infections after open-heart surgery. After institutional approval and informed consent, 392 patients were
included in a randomized, prospective study. Nasal cultures were taken for all patients before surgery. Patients were
divided in two groups : Group I [n=190] receiving mupirocin in the anterior nares 4 times daily for 48 hours before
surgery; Group II [n=202] was the control group. Patients were followed for a month after surgery. All mediastinal,
sternal, pulmonary and cutaneous infections were documented and treated with appropriate antibiotics. A Student test
for quantitative data and a X [2] test for qualitative data were used for statistical analysis. p</=0.05 was considered
significant. The two groups had the same demographic characteristics and risk factors. Nasal carriage of
Staphylococcus was 36.2% in the two groups. Neither mediastinitis nor sternitis were noticed in any of the two groups.
There was no statistical difference between the groups according to the frequency of the cutaneous infections [Group I
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: 19/190-Group II : 13/202] and pneumonia [Group I : 7/190-Group II : 13/202]. In patients who had nasal carriage of
Staphylococcus, nasal decontamination has not shown a statistical difference of cutaneous infections of the lower
limbs nor pneumonia. Although nasal decontamination reduced the incidence of sternal wound infection [Gr I 0/190-Gr
II 4/202; p=0.017]. Staphylococcus aureus, in the control group, induced more cutaneous infections [30.8% vs 11.7%;
p=0.048]. The usage of mupirocin for nasal decontamination before open-heart surgery reduces the incidence of the
sternal wound infection, and does not seem to affect the frequency of cutaneous infections of the lower limbs nor
pneumonia after this surgery.
Mycobacterium bovis
isolation and purification
Prevalence of bovine infection with mycobacterium bovis some Egyptian Governorates.
Mossad, A.A.; Radwan, G.S.; Samaha, H.A.; Nasr, E.A.; El Battawy, E.H.
Minufia University - Faculty of Veterinary Medicine - Department of Bacteriology, Immunology and Mycology
Veterinary Medical Journal 2009; 57 (1): 35-52 (57 ref.)
Keywords: Cattle; Prevalence; Tuberculin Test; Polymerase Chain Reaction
Abstract: One hundred and thirty seven [4.6%] out of 3000 cattle at different ages from seven governorates of Egypt
[Qualubia, Sharkia; Gharbia, Giza, Behira, Sohag and Ismailia] were found positive for tuberculosis by single
inradermal [SID] tuberculin Bacteriological examination of tested samples from slaughtered reactor cattle revealed the
isolation and identification of Mycobacterium bovis [M. bovis] and Mycobacterium other than tuberculosis [MOTT] in 90
[65.7%] and 7 [5.1%] samples, respectively. One hundred and eight [78.83%] serum samples out of 137 tuberculin
reactors were found positive for enzyme linked immunosorbent assay [ELISA] by using test. Post mortem [PM]
examination of slaughtered reactor cattle revealed tuberculous visible lesions [VL] and non-VL [NVL] in 94 [68.6%] and
43 [31.4%] animals, respectively. Tuberculous lesions were observed in 41 29.9%], 19[13.9%], 20 [15%] and 14
[10.2%] in 137 slaughtered reactor cattle with pulmonary, digestive, mixed and generalized VL, respectively. M.bovis
synthetic early secretory antigenic target 6 peptide antigen [ESAT6-p]. Polymerase chain reaction [PCR] amplification
assay was performed on selected tissues samples from 10 slaughtered tuberculin reactors with pulmonary, digestive,
mixed or generalized VL, or NVL. Eight [80%] out of the 10 samples gave positive results with PCR assay. On the
other side, only 6 [60%] and 7 [70%] of these samples were found positive for M.bovis isolation and ELISA,
respectively. The results obtained in the present study point to the importance of the periodical tuberculin testing of
animals, use of ELISA assays with M.bovis-specific antigens as a complimentary diagnostic toot to tuberculin test and
application of PCR test for direct and rapid diagnosis of tuberculosis. Improvement of diagnostic assays for M.bovis
may be of value in the effectiveness of test and slaughter eradication programs of bovine tuberculosis in governorates
of Egypt.
Mycoplasma
isolation and purification
Isolation of mycoplasma gallisepticum and mycoplasma synoviae from native, ross and
lohmann chickens in hail region of Saudi Arabia.
Alkhalaf, Abdullah N.; Harbi, Khaled B.; Alshamary, H.; Hashad, M.
Qassim University - College of Agriculture and Medicine - Department of Vet. Medicine
Veterinary Medical Journal 2009; 57 (1): 67-75 (22 ref.)
Keywords: Chickens; Mycoplasma gallisepticum; Mycoplasma synoviae
Abstract: In this study, M gallisepticum and M synoviae were isolated from different breeds of chickens in Flail region
of Saudi Arabia. Out of 200 samples [trachea, lungs, air sacs and synovial swabs] taken from native chickens of
different ages, 100 pure mycoplasma isolates were recovered. When typed by morphological, biochemical and
serological methods, 39 isolates were identified as M synoviae, 31 isolates were identified as M. gallisepticum. of 60
samples from Lohmman layers, 11 pure isolates were obtained and 6 of them were identified as M synoviae, I was M
gallisepticum. of 140 samples collected from Ross chickens and breeders, only samples collected from breeders aging
8 14 weeks [40 samples] resulted in positive mycoplasma isolation. Fifteen pure mycoplasma isolates were recovered
of which 3 were identified as M gallisepticum, 4 were identified as M synoviae. Tracheal samples and synovial fluids
resulted in the highest isolation rates from native and Lohmman chickens, respectively while synovial fluid and tracheal
samples resulted in equal rates of Mycoplasma isolation from Ross chickens. Agar media containing tryptone soy agar
base resulted in bigger Mycoplasma colonies and nipples.
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Myelodysplastic Syndromes
diagnosis
Clinico-haematological characteristics in Pakistani patients of primary myelodysplastic
syndrome according to world health organization classification.
Ehsan, Ayesha; Aziz, Mona
E-mail:[email protected]
Shaikh Zayed Postgraduate Medical Institute - Department of Haematology, Lahore
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 232-236 (25 ref.)
Keywords: Myelodysplastic Syndromes-blood; Myelodysplastic Syndromes-classification; World Health
Organization; Age Distribution
Abstract: To assess the applicability of WHO classification on a cohort of Pakistani myelodysplastic syndrome [MDS]
patients, and determine their epidemiological and clinico-pathological features. Case series. Haematology Department,
Shaikh Zayed Hospital, Lahore, from April 2004 to March 2006. Forty six patients of primary MDS diagnosed by World
Health Organization [WHO] criteria were included in the study by nonprobability purposive sampling. The cohort was
classified accordingly and the epidemiological, clinical and haematological parametres were assessed. Descriptive
statistics were used to describe the data. Forty six patients [28 males and 18 females] of primary MDS were included in
the study. The mean age was 46.21 years. According to the WHO classification, 12 cases of refractory anaemia, 24
cases of refractory cytopenia with multi lineage dysplasia, 1 case of refractory cytopenia with multi lineage dysplasia
and ring sideroblasts, 3 cases of MDS unclassified and 3 cases each of refractory anaemia with excess of blasts I and
II were diagnosed. Symptomatic anaemia was seen in 37 cases and pancytopenia was documented in 33 cases.
Dyserythropoiesis affected 41 cases. Grade III reticulosis was seen in 7 cases. ALIP was present in 13 cases. MDS
presented at a young age. Refractory cytopenia with multi lineage dysplasia was the dominant disease category.
Further studies are suggested for identifying the cytogenetic abnormalities and del 5q- category.
Myeloproliferative Disorders
Evolution of marginal zone lymphoma towards myeloproliferative disorder: a case report.
Arabi, Abdessamad; Brahimi, M.; Bekadja, M.A.; Saidi, D.; Touhami, H.
E-mail:[email protected]
University Hospital 1[st] November 1954 - Department of Haematology and bone marrow transplantation
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 171-174 (9 ref.)
Keywords: Lymphoma, B-Cell, Marginal Zone; Prognosis; Flow Cytometry; Molecular Biology
Myxoma
diagnosis
Aggressive angiomyxoma of scrotum presenting as an Inguinal Hernia.
Rehman, Safia; ul Muqim, Rooh; Gul, Tamjeed; Wazir, Mohammad Aziz; Zarin, Muhammad
E-mail:[email protected]
Khyber Teaching Hospital - , Surgical C Unit
Pakistan Journal of Medical Sciences 2010; 26 (2): 478-481 (12 ref.)
Keywords: Myxoma-pathology; Hernia, Inguinal-diagnosis; Scrotum-pathology
Abstract: Aggressive Angiomyxoma [AAM] is a rare mesenchymal tumor with a locally aggressive course. The most
common location is in the pelviperineal region and occurs mostly in females of childbearing age. In males, it is
extremely rare and thus is apt to be mistakenly diagnosed as an inguinal hernia or hydrocele. We report a case of 45
year old man who had right sided scrotal swelling for about four years. It was diagnosed as an inguinal hernia clinically.
On further investigations, it was found to be a soft tissue tumor of the scrotum. The patient underwent scrotal
exploration. At surgery, a huge lobulated gelatinous mass surrounding the right testicle was found. The mass was
excised including the testicle and sent for histopathological analysis. Histologic examination of the excised mass
revealed a nonencapsulated lesion composed of sparse spindle-shaped cells and a myxoid stroma with a prominent
vascular component. The cells showed focal and weak positivity for desmin. The findings were thus consistent with
aggressive angiomyxoma of the scrotum. The margins of the specimen were clear. The patient we report has so far
done well with no evidence of recurrence.
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Necrobiotic Disorders
diagnosis
An unusual skin presentation of necrobiotic xanthogranuloma.
Dilnawaz, Mansoor
E-mail:[email protected],com
Pilgrim Hospital - Department of Dermatology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 274-275 (10 ref.)
Keywords: Skin Manifestations; Xanthogranuloma, Juvenile; Paraproteinemias-diagnosis; Prognosis
Abstract: A well appearing 73-year-old Caucasian lady presented with a long-standing history of yellowish atrophic
lesions on her limbs and trunk. The lesions were asymptomatic. These were found to be consistent with the diagnosis
of Necrobiotic Xanthogranuloma [NXG] on histology. The reported patient did not have the characteristic skin changes
and instead had unusual lesions reminiscent of morphoea not described in the literature. She reported no associated
systemic symptoms.
Neoplasms
epidemiology
Cancer epidemiology in Lebanon.
Shamseddine, Ali I.; Musallam, Khaled M.
American University of Beirut Medical Center - Hematology and Oncology Division - Department of Internal Medicine
MEJC - Middle East Journal of Cancer 2010; 1 (1): 41-44 (10 ref.)
Keywords: Registries; Sex Distribution; Incidence; Risk Factors; Age Distribution; Early Detection of Cancer; Breast
Self-Examination
Abstract: The main obstacle facing cancer preventive strategies worldwide is a lack of well conducted
epidemiological studies to guide local and international efforts for disease control. In Lebanon, long due political strain
has added yet another obstacle to the development of methodologies aiming to collect data on cancer epidemiology.
However, through several efforts dated from the 1960s the picture is becoming clearer. We herein review the outcome
of all such efforts and their interpretation as a guide for future preventive strategies.
Trend of childhood cancers in Iraq after the two gulf wars.
Lafta, Riyadh K.; Abdulrazaq, May R.; Al Shujairi, Tariq A.
E-mail:[email protected]
Mustansiriya Uuniversity - College of Medicine
JABHS - Journal of the Arab Board of Health Specializations 2010; 11 (1): 48-54 (33 ref.)
Keywords: Prevalence; Age Distribution; War
Abstract: This study was conducted to find out the rates of childhood malignancies in Baghdad hospitals, and to
study the changes in the trend of these diseases in three periods of time after the first and the second Gulf war. This
hospitAl based record study was conducted during the period from February through June 2007 in the two main
centers of childhood oncology in Baghdad; Children Welfare Teaching Hospital, and Child's Central Teaching Hospital.
All the records of patients [age between 0-15 years and diagnosed as having malignant diseases during the following
three periods] were included. The first period includes the years [1990, 1991], the second period [1997, 1998], and the
third period includes the years [2004, 2005]. The total sample was 2013 patients; 1172 males and 841 females; 462
patients were diagnosed in the first period, 688 in the second and 863 patients in the third period. The study showed a
slight increase in the rate of childhood malignancies over the three periods [3.46, 3.52, and 4.04] /100000/ year
respectively. There was an increase in the number of cases in all age groups especially patient's age less than 5
years. The male: female ratio was 1.4:1 with no significant change through the 3 periods. Leukemia was the most
common childhood malignancy followed by lymphoma and solid tumors [1202, 421, and 332] patients respectively. The
majority of patients live in the middle region of Iraq with the highest frequency from Baghdad. There is an increase in
the survival percentage [9.9%, 25.5%, and 32.4%] and decrease in fatality percentage over the three periods [41.3%,
32.4%, and 27.9%] respectively. There is an increase in the rate of childhood cancer in Iraq during the studied period,
with no detectable changes in the trend regarding the type, and geographical distribution.
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Nutrition Assessment
Anthropometric assessment of nutritional status and socio-demographic characteristics in
children up to 2 years of age.
Shahid, Anjum; Ramzan, Afroze; Memon, Ashfaque
National Institute of Child Health - PMRC Specialized Research Centre on Child Health
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 10-13 (22 ref.)
Keywords: Nutritional Status; Anthropometry; Cross-Sectional Studies; Questionnaires; Socioeconomic Factors;
Malnutrition
Abstract: Malnutrition is one of the major causes of morbidity and mortality in children. It is important to realize that
normal length and weight being attained at 1 year of age, would predict the nutritional status at 3 years of age. To
asses the nutritional status and the associated socio-demographic characteristics in supposedly healthy children of up
to 2 years of age and highlight the importance of anthropometric measurements in routine child health care. A
crosssectional study using purposive sampling technique was conducted on children attending well baby clinic of
National Institute of Child Health, Karachi during the year 2003-2005. Anthropometric measurements i.e. height and
weight, were measured and a standard questionnaire was used to interview the mothers regarding sociodemographic
back ground information after a verbal informed consent and ensuring confidentiality. Height for age, weight for age
and weight for height of the children were compared with the National Centre of Health Statistics [NCHS] reference
population of the United States, and Z-score < -2 SD were considered as stunted, under weight and wasted
respectively. Data was analyzed using SPSS software package. We observed stunting in 22%, wasting in 15% and
under weight in 31.6% children. Majority of children with low weight were between 19 - 24 months of age. Regarding
socio-economic status of the households, 53.8% had family income less than Rs6000 /month and almost 50% had a
family size of 6-10 persons. Parents' education to the level of illiteracy [father, 27% and mother, 40%] and incomplete
immunization [20%] were other associated factors for stunting, wasting and under weight. About 32% of children up to
2 years of age in the selected population were under weight, followed by stunning [22%]. Anthropometric measurement
of children is a useful in routine child care settings as it will facilitate early identification and timely interventions for
emerging health problems.
Obesity
complications
Pattern of obesity and associated diabetes in Lebanese adolescents: a pilot study.
Salameh, P.; Barbour, B.
E-mail:[email protected]
Lebanese University - Faculty of Public Health
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 226-230 (27 ref.)
Keywords: Diabetes Mellitus-epidemiology; Body Mass Index; Blood Glucose; Overweight-complications;
Questionnaires; Cross-Sectional Studies; Comorbidity; Risk Assessment; Students
Abstract: Obesity-associated diabetes in adolescents is increasing throughout the world. In this study, body mass
index and capillary blood glucose were measured in a randomly selected sample of adolescents from 3 Lebanese
private schools. Obesity was evaluated according to international Obesity Task Force cut-offs. Out of 300 students,
18.7% were at risk of obesity 3.0% were obese. Random glycaemia level was >/= 140 mg/dL in 10.3% of students. In
those fasting, 10.5% had glucose intolerance and 3.5% had diabetes. Glucose levels were significantly higher in
overweight versus normal weight individuals: 86 [SD 13] versus 96 [SD 16] mg/dL. Among the normal weight group
8.6% had abnormal glycaemia while among those who were overweight 37.0% had abnormal glycaemia. Lebanese
school students have high rates of overweight and of obesity-associated diabetes and glucose intolerance.
epidemiology
The association between obesity and blood pressure among adolescents in Dubai, UAE.
Bin Zaal, Afra A.; Musaiger, Abdulrahman O.; D'Souza, Reshma
Ministry of Health - Department of Preventive Medicine
Pakistan Journal of Medical Sciences 2010; 26 (2): 271-276 (27 ref.)
Keywords: Blood Pressure; Body Mass Index
Abstract: To investigate the association between obesity and the risk of elevated blood pressure [BP] in adolescents
in Dubai, United Arab Emirates [UAE]. Representative sample of 661 adolescents aged 12 to 17 years were selected
by means of a multistage stratified random sampling technique. The mean body mass index [BMI] of males was higher
than that of females at all ages except at 13 years of age, where the females had higher mean BMI values [24.1kg/m2]
compared to males [21.9 kg/m2]. Males had higher levels of systolic blood pressure [SBP] [117.1mm Hg-126.8 mm Hg]
than females [109.2mmHg-117.1mmHg]. The prevalence of high SBP increased as the weight increased, as 50% of
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males with high SBP were obese, compared with 62.5% among females. Male and female adolescents with elevated
SBP were 5 times [95% CI 2.3, 9.7] and 16 times [95% CI 3.5, 17.3] respectively, more likely to be obese compared to
those with normal SBP. Similarly, those with elevated diastolic blood pressure [DBP] were two times [95% CI 1.1, 4.4]
and four times [95% CI 1.6, 8.5] more likely to be obese compared to those with DBP in the normal range. The high
prevalence of obesity among adolescents in Dubai and its association with high BP calls for urgent action to prevent
and control obesity in this age group.
Olfactory Bulb
ultrastructure
Morphological and quantitative features of mitral cells in the rat olfactory bulb after
administration of propranolol.
Khilji, Muhammad Saad; Tahir, Mohammad; Jafari, Fahim Haider
E-mail:[email protected]
University of Health Sciences - Islamabad Medical and Dental College - Department of Anatomy
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 237-241 (24 ref.)
Keywords: Olfactory Bulb-drug effects; Propranolol; Rats, Sprague-Dawley; Olfactory Bulb-anatomy and histology
Abstract: To determine the cytoplasmic morphological changes in the mitral cells and quantitative changes [number
of mitral cells and thickness of mitral cell layer in microns] in the rat olfactory bulb after administration of propranolol.
Experimental study. The Department of Anatomy, University of Health Sciences, Lahore, from January 2006 to
January 2007. Twenty samples were obtained from two randomly divided groups of rats, each comprising 10 animals
for control and experimental work respectively. Each group was treated with normal saline [5 ml/kg] and propranolol [1
mg/kg] respectively for one month. The skull was fixed in 20% formalin for 10 days and decalcified in 10%
formalin/10% nitric acid. The olfactory bulb along with olfactory cortex was dissected. After processing, 10 microns
thick sections were obtained. The slides were stained with Hematoxylin and Eosin and Bielschowksy's silver stain
[Glees-Marsland modification] and studied under light microscope. The morphology, quantitative analysis of mitral cell
layer and the number of mitral cells were studied in the histological study and compared using t-test with significance at
p < 0.05. In the propranolol treated group changes observed in the morphology of the mitral cells included presence of
cytoplasmic vacuoles at the periphery of the cells. There was significant increase in the thickness of mitral cell layer
and number of the mitral cell in the propranolol treated group [p < 0.05]. This study showed morphological and
quantitative changes in the olfactory bulb in response to treatment with propranolol, hence it has implications in odour
induced learning.
Oral Health
Oral health of Iranian children in 2004: a national pathfinder survey of dental caries and
treatment needs.
Bayat Movahed, S.; Samadzadeh, H.; Ziyarati, L.; Memory, N.; Khosravi, R.; Sadr Eshkevari, P.S.
E-mail:[email protected]
Tehran University of Medical Sciences - Faculty of Dentistry
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 243-249 (15 ref.)
Keywords: Dental Caries-epidemiology; Dental Health Surveys; DMF Index; Prevalence; Needs Assessment
Abstract: A second nationwide survey in 2004 aimed to describe the oral health status of children in the Islamic
Republic of Iran and to provide baseline data for the organization and evaluation of the national oral health promotion
programme. WHO pathfinder sampling procedures were used to select representative samples of children aged 3, 6, 9
and 12 years. Data on decayed/missing/filled teeth, caries-free rates and treatment needs were collected from 18 946
children using WHO standard methods. The mean dmft/DMFT indices were 1.9/- for 3-year-olds, 5.0/0.2 for 6-yearolds, 3.6/0.9 for 9-year-olds and 0.6/1.9 for 12-year-olds. Significant differences in dental caries prevalence were found
according to sex, province, urban/rural residence, family income and parents' level of education.
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Orbit
surgery
A combined surgical and prosthetic approach for the successful management of a mutilated eye
socket: a case report.
Prithviraj, D.R.; Khare, Sumit; Gupta, Anish; Shruthi, D.P.
Government Dental College and Research Institute - Department of Prosthodontics and Implantology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 129-132 (6 ref.)
Keywords: Orbit-injuries; Prostheses and Implants; Reconstructive Surgical Procedures-methods
Abstract: Facial disfigurement through the loss of an eye due to a road traffic accident can be devastating for the
patient and may leave few options for an ophthalmologist, especially if the situation demands urgency. In the present
case report, the patient had a major accident, which resulted in the severe disruption of the socket. The requirements
of the prosthodontist regarding the morphology of the socket guided the ophthalmologist to undertake reconstructive
surgery. The prosthesis was then fabricated such that both its longevity and the morphology of the socket were safe
guarded.
Orthodontics, Interceptive
education
Impact of an educational leaflet on parents' knowledge and awareness of children's orthodontic
problems in Shiraz.
Oshagh, M.; Danoei, S. Momeni; Ghahremoni, Y.; Pojuhi, N.; Boushehri, S. Ghodsi
E-mail:[email protected]
Shiraz University of Medical Sciences - Faculty of Dentistry - Shims Orthodontic and Educational Research Centre,
Department of Orthodontics
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 121-125 (22 ref.)
Keywords: Parents; Knowledge; Awareness; Malocclusion; Questionnaires; Prospective Studies; Teaching
Abstract: Raising parents' awareness about dentofacial malocclusions is important for avoiding delays in seeking
treatment. The aim of the present research was to assess the impact of an educational leaflet on parent's knowledge
and awareness of orthodontic malocclusion in children. Parents of 533 7-9-year-old schoolchildren were randomized
into a leaflet group who received an educational leaflet and a control group with no leaflet. Pre-and post-intervention
test scores on a questionnaire about orthodontic problems were compared. Differences between post- and pre-test
scores were significantly higher in the leaflet group than the control group for the total score and the domain on general
awareness of orthodontic problems. Scores on the domain of knowledge of referral intervals did not differ significantly.
Information leaflets may be useful for increasing parents' awareness of orthodontic problems in children.
Osteoma, Osteoid
diagnosis
Osteoid osteoma of the patella presenting as chronic anterior knee pain case report and review
of the literature.
Mehdinasab, Seyed Abdol Hossein; Sarrafan, Nasser; Alvavinejad, Pooyan
E-mail:[email protected]
Jondishapur University of Medical Sciences - Imam Khomeini Hospital - Department of Orthopedic surgery
Pakistan Journal of Medical Sciences 2010; 26 (2): 490-493 (27 ref.)
Keywords: Patella-pathology; Knee Joint-pathology; Pain-etiology; Osteoma, Osteoid-radiography; Tomography, XRay Computed
Abstract: Osteoid osteoma is a benign bone forming tumor with a characteristic radiographic appearance. Femur
and tibia is the frequent site of involvement. Osteoid osteoma in the patella is a rare condition of which only a few
cases have been reported in the literature. Non-specific knee pain, difficulty to distinguish nidus, and lack of typical
sclerotic bone formation in plain radiographs cause a delay in diagnosis. We report a 15 years old girl with anterior left
knee pain since 1.5 year. Imaging findings and biopsy of the lesion confirmed osteoid osteoma. The pain was relieved
after surgical resection of the tumor and patient was symptom free with no evidence of recurrence at 12 months after
surgery.
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Overweight
epidemiology
Prevalence of overweight and obesity and associated risk factors in urban primary-school
children in Babol, Islamic Republic of Iran.
Hajian Tilaki, K.O. ; Sojjodi, P.; Razavi, A.
E-mail:[email protected]
Babol University of Medical Sciences - Babol Faculty of Medicine - Department of Social Medicine and Health
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 109-114 (29 ref.)
Keywords: Obesity-epidemiology; Risk Factors; Students; Schools; Urban Population; Questionnaires; CrossSectional Studies; Body Mass Index; Prevalence
Abstract: Childhood obesity is a major public health problem globally because of changes in lifestyles. We assessed
the prevalence of overweight/obesity and associated factors in urban schoolchildren in Babol in a cross-sectional study
of 1000 schoolchildren aged 7-12 years. Weight and height were measured and data on sports activities and leisure
time physical activities were collected by questionnaire. Overweight/obesity were assessed by comparing body mass
index [BMI] values to the BMI index for age and sex percentiles set by CDC, Atlanta. The prevalence of obesity and
overweight was 5.8% and 12.3% respectively. The prevalence was significantly lower in girls compared with boys [ageadjusted OR= 0.69, 95% Cl: 0.50-0.96] and higher among private-school educated children compared with publicschool educated students [age adjusted OR = 2.17, 95% Cl: 1.47-3.18]. For each additional score of leisure time
physical activity, the age-adjusted OR decreased significantly.
Pain
etiology
[Chronic pain in children and adolescents: a review].
Huijer, Huda Abu Saad
American University of Beirut - School of Nursing - Faculty of Medicine
LMJ - Lebanese Medical Journal 2010; 58 (2): 105-110 (45 ref.)
Keywords: Chronic Disease; Pain-epidemiology; Pain Measurement; Family; Pain-drug therapy; Pain-therapy
Abstract: Chronic pain in children has been increasing in prevalence and studies have provided evidence that it
impacts the functional/physical aspects of the children's life and their psychological and emotional well-being. Family
caregivers of children and adolescents with chronic pain suffer a great sense of burden affecting their emotional,
social, and family functioning. The problem is also exacerbated by the additional financial burden secondary to
increased physician consultation and medication use. A better understanding of pain in children is needed in order to
gain insight in the etiology. The aim of the following article is to provide a review of the literature on the prevalence of
chronic pain in children and adolescents and the factors associated with it.
Pancreatic Neoplasms
genetics
Differences in molecular pathologic characteristics of pancreatic adenocarcinoma between
Egyptian and Moroccan patients.
Robinson, Sara; Soliman, Amr S.; Karkouri, Mehdi; Omer, Hoda Gad; Greenson, Joel R.
University of Michigan - School of Public Health - Department of Epidemiology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 27-36 (17 ref.)
Keywords: Pancreatic Neoplasms-pathology; Adenocarcinoma-genetics; Pathology, Molecular; Mutation-genetics;
Genes, ras
Abstract: Pancreatic cancer has not been well studied, especially in developing countries. We studied the variations
in genetic mutations in pancreatic adenocarcinoma between Moroccan and Egyptian populations. The molecular
pathology of 30 tumors from a large hospital in Casablanca, Morocco were examined and compared with the findings
of 44 tumors from the Gharbiah Governate in Egypt. K-ras mutations in codons 12 and 13 in addition to p53 mutations
in exons 5-8 were evaluated. Overall, differences in the rates of K-ras mutations were not statistically significant [48.00
and 34.09%, respectively]; however differences in rates of p53 mutations were statistically significant with p53
mutations more common in Moroccan tumors than in Egyptian tumors [46.67 and 16.28%, respectively]. G ->T
mutations of the K-ras gene were most commonly seen Egyptian tumors, whereas G -> A mutations were the most
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common type of mutations in Moroccan tumors. Logistic regression analysis showed that a p53 mutation in any exon
as well as a p53 mutation in exon 5 predicted the country of residence and those mutations occurred more frequently
in Moroccan patients. Our study shows that differences exist within the Arab population in the molecular pathology of
both the K-ras and p53 genes. Further studies are necessary to clarify the differences in molecular pathways of
pancreatic cancer in the Middle East and to investigate the role of environmental and/or genetic factors related to those
pathways.
Paternity
A long-term baby mix-up case in the Eastern Mediterranean region.
Tug, A.; Ozguven, H.D.
E-mail:[email protected]
University of Ankara - Faculty of Medicine - Department of Forensic Sciences
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 257-259 (7 ref.)
Keywords: DNA Fingerprinting; Parents; Family; Adaptation, Physiological
Patient Satisfaction
Satisfaction of patients staying in day surgery clinic from nursing services.
Ozlu, Zeynep Karaman; Ozer, Nadiye; Arslan, Sevban; Cantekin, Isin
E-mail:[email protected]
Ataturk University - Health Sciences Faculty
Pakistan Journal of Medical Sciences 2010; 26 (2): 438-443 (19 ref.)
Keywords: Nursing Services; Nursing Service Hospital; Ambulatory Surgical Procedures-nursing; Questionnaires
Abstract: To examine day surgery patients' satisfaction levels with nursing services using Scale of Patient
Perception of Hospital Experience with Nursing [PPHEN]. The study design was descriptive. Data were collected by
the researcher in the Day Surgery clinic of a university hospital in Turkey. Participants with literacy were 18 years old
and older. The sample included 148 patients agreeing to participate in the study. Data were collected using a
questionnaire including socio-demographic questions for patients and PPHEN Scale, Turkish Version adapted to
Turkish by Coban. The data were assessed through descriptive statistics, t-test, Man-Whitney U Test and Kruskal
Wallis variance analysis. When PPHEN point averages according to age were compared, the point average for the age
group of 66 years and above was 72.78 [SD=8.28], for the age group of 19 to 40, 68.26 [SD=11.6]; and the difference
between these points was found statistically significant [P=0.041]. For PPHEN point averages according to patients'
educational backgrounds, it was 70.50 [SD=10.19] for primary school graduates, 64.57 [SD=15.97] for university
graduates; and the difference was found statistically significant [P=0.000]. In this study, it was, in general, found out
that the patients were satisfied with the nursing services.
Pericarditis, Constrictive
microbiology
Rapidly progressive effusive constrictive
staphylococcus aureus [MSSA].
pericarditis
caused
by
methicillin
sensitive
Akhtar, Naveed; Khalid, Ayesha; Ahmed, Waqas; Rasheed, Khalid
E-mail:[email protected]
Shifa International Hospital - Department of Cardiology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 271-273 (10 ref.)
Keywords: Staphylococcus aureus; Methicillin; Pericardial Effusion-microbiology; Thoracic Injuries-complications
Abstract: Effusive-constnctive pericarditis is a clinical syndrome characterized by concurrent pericardial effusion and
pericardial constriction, where constrictive hemodynamics are persistent after effusion is drained. It may present at any
point along the clinical course, from the occurrence of an effusion to the development of chronic pericardial
constriction. We refer an unusual case of effusive constrictive pericarditis developing rapidly within days, following
purulent pericarditis secondary to chest trauma.
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Perinatal Mortality
Perinatal Mortality contributors in singleton gestation.
Sajjad Ur Rahman
E-mail:[email protected]
Hamad Medical Corporation - Women's Hospital
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 290-291 (6 ref.)
Keywords: Birth Weight; Gestational Age; Infant, Premature
Phacoemulsification
adverse effects
Completing phaco following anterior capsular tear.
Little, Brian
Moorfields Eye Hospital NHS Foundation Trust
Saudi Journal of Ophthalmology 2010; 24 (3): 95-99 (8 ref.)
Keywords: Phacoemulsification-methods; Capsulorhexis; Lens Capsule, Crystalline-injuries
Abstract: A primary tear-out of the capsulorrhexis or a later anterior capsule tear occurs in less than 1% of
phacoemulsification procedures [Marques et al., 2006]. It is a relatively uncommon complication but a hazardous and
important one, although comparatively little has been published on its management. With the nucleus still in the bag at
this stage, the surgeon is faced with the sizeable challenge of completing surgery without propagating a wrap-around
tear to the posterior capsule. These are perilous conditions to face, but by using the right techniques the surgeon can
still prevail. There is a clear set of principles that are based on self-knowledge of the surgeon's own skills and
experience, combined with their understanding of how to control the forces acting on the tear and the tolerances of the
capsular bag to surgical manipulation. Applying these principles in practice has enabled the development of a range of
techniques now available to safely remove the nucleus under these challenging conditions. However, by far the most
important principle of all is that if in doubt, not to proceed.
Pharmacogenetics
[Pharmacogenetics and personalized medicine: the future for drug prescribing].
Mitri, Zahi; Esmerian, Maria O.; Simaan, Joseph A.; Sabra, Ramzi; Zgheib, Nathalie K.
American University of Beirut - Faculty of Medicine - Department of Pharmacology and Therapeutics
LMJ - Lebanese Medical Journal 2010; 58 (2): 101-104 (27 ref.)
Keywords: Individualized Medicine; Toxicology; Polymorphism, Genetic; Genotype
Abstract: Pharmacogenetics, the study of interindividual variations in DNA sequence related to drug response, aims
at the optimization of treatment regimens based on each patient's unique genetic makeup. Currently, there is a trend
towards moving away from the concept of "one drug fits all" to a rather more individualized and personalized medicine.
The goal is to define the appropriate drug dose that maximizes efficacy and minimizes toxicity in each individual
patient. An example of genotyping for CYP2C9 genetic polymorphisms in patients receiving oral anticoagulants is
provided. In spite of its inherent challenges, we hope that pharmacogenetic research and clinical applications expand
to improve healthcare outcomes in Lebanon and worldwide.
Physician's Practice Patterns
Determinants of physicians' medication prescribing behaviour in primary care in Riyadh city,
Saudi Arabia.
Magzoub, M.A.; Neyaz, Y.; Khoja, T.; Qureshi, N.A.; Haycox, A.; Walley, T.
King Ahdulaziz Medical City - College of Medicine - Department of Medical Education
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 160-166 (23 ref.)
Keywords: Drug Prescriptions; Behavior; Primary Health Care; Physicians, Primary Care; Questionnaires;
Knowledge
Abstract: This study in Saudi Arabia explored the determinants of physicians' prescribing behaviour in primary care
in Riyadh city. A self-administered questionnaire designed to explore factors influencing prescribing [sociodemographic
factors; practice access to educational materials; pharmaceutical company representatives, and patients factors] was
completed by 87 PHC physicians. A factor analysis of 56 variables extracted 7 factors that explained 46% of the
variance. Of these, 4 components positively related to perceived good prescribing behaviour could be summarized as:
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clinical experience of physicians; use of educational materials for continuous updating of medical knowledge;
enhanced levels of continuing medical education and willingness to involve patients in decision-making; and working
as a team using pharmacists for consultation and emphasizing the role of medical education.The other 3 factors
derived from the analysis were less easy to interpret and may have been statistical anomalies [or measurement errors].
Physician-Patient Relations
"I found it on the internet": preparing for the e-patient in Oman.
Masters, Ken; Ng'ambi, Dick; Todd, Gail
E-mail:[email protected]
IT Health Ed
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 169-179 (52 ref.)
Keywords: Internet; Education, Medical; Diffusion of Innovation; Communication
Abstract: In the Information Age, the communication patterns between doctor and patient are changing. Using
Everett Rogers' theory of Diffusion of Innovations, this paper begins by examining the diffusion of the Internet in the
world and in Oman. It then considers the emergence of e-patients. The characteristics of e-patients are described in
some detail. The paper ends by describing steps that should be taken when teaching medical students in Oman so that
they can be prepared for e-patients.
Plant Extracts
pharmacology
Analgesic and antiinflammatory activity of methanolic extract of acalypha indica linn.
Rahman, M. Aminur; Bachar, Sitesh C.; Rahmatullah, Mohammed
University of Development Alternative - Department of Biotechnology and Genetic Engineering
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 256-258 (15 ref.)
Keywords: Analgesics-pharmacology; Euphorbiaceae-chemistry; Mice; Rats
Abstract: Previous phytochemical analysis of methanolic extract of Acalypha indica L. has indicated the presence of
steroid, flavonoid and terpenoid types of compounds. Since these compounds are of pharmacological interest, coupled
with the use of this plant in traditional medicine, prompted us to check A. indica L. for possible analgesic and
antiinflammatory activities. The methanolic extract of A. indica L. showed statistically significant [P<0.001] analgesic
activity in mice in a dose-dependent manner. A sustained and significant [P<0.001] inhibition of carrageenan-induced
inflammation of rat paw was observed with 125 mg/kg and 250 mg/kg body weight. The methanolic extract of A. indica
L. also demonstrated antiinflammatory effect in a dose-dependent manner. Maximum inhibition by the extract was
observed at 250 mg/kg body weight after three hours of ingestion, which was comparable to that of the standard drug
phenylbutazone at a dose of 100 mg/kg body weight. The obtained results provide a support for the use of this plant in
traditional medicine.
Antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from super
ficial skin infection.
Pirzada, A.J.; Shaikh, W.; Usmanghani, K.; Mohiuddin, Ejaz
E-mail:[email protected]
University of Sindh - Institute of Botany
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 337-340 (26 ref.)
Keywords: Sapindaceae; Antifungal Agents-pharmacology; Dermatomycoses-microbiology; Fungi-drug effects
Abstract: Antimicrobial activity of solvent extracts of leaves and shoot of Dodonaea viscosa Jacq have been
determined against fungi, Aspergillus niger, Aspergillus flavus, Paecilomyces varioti, Microsporum gypseum, and
Trichophyton rubrum causing skin diseases. All crude extracts were found to be effective against tested fungi. However
chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous
extracts. More over in present study some basic elements have been analyzed, Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn
from the medicinal plant Dodonaea viscosa Jacq. by using atomic absorption spectrophotometry and UV
spectrophotometry. The medicinal plant Dodonaea viscosa Jacq contains considerable amount of elements which
have therapeutic effects in skin diseases.
Bioactivity of major components from the seeds of bunium persicum [boiss.] fedtch.
Sharififar, Fariba; Yassa, Narguess; Mozaffarian, Valiolah
E-mail:[email protected]
Kerman University of Medical Sciences - School of Pharmacy - Department of Pharmacognosy
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 300-304 (19 ref.)
Keywords: Apiaceae-chemistry; Seeds-chemistry; Antioxidants-pharmacology; Oils, Volatile-pharmacology
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Abstract: Zire Kermani [Bunium persicum] is an Iranian plant which is commonly used as antispasmodic,
carminative, anti obesity and lactogage. The essential oil and different extracts of the seeds of this plant were
evaluated for antioxidant activity by three complementary methods: DPPH assay, beta-carotene bleaching and
ammonium thiocyanate methods. The oil and methanolic extract of B. persicum exhibited the highest antioxidant
activity with IC50=23.4 +/- 1.6 and 45.7 +/- 3.6 micro gmL-1 in DPPH assay and the most inhibition of beta-carotene
oxidation and lipid peroxidation. The GC/MS analysis of the essential oil of B. persicum indicated the gammaTerpinene [46.1%] and cuminaldehyde [15.5%] as the major components of the oil. Furthermore the active methanol
extract of the plant was fractioned by column chromatography to afford several fractions, of which in more purification,
kaempferol, caffeic acid and p-coumaric acid were found to be the antioxidant components of this extract. These
results confirm the in vitro antioxidant and radical scavenging activity of the essential oil and methanolic extract of B.
persicum, which warranty the use of the plant in many traditional uses.
Hypoglycaemic activity of ethyl acetate fraction of the leaf extract of Telfairia occidentalis.
Eseyin, O.A.; Ebong, P.; Eyong, E.U.; Umoh, E.; Agboke, A.
E-mail:[email protected]
University of Uyo - Faculty of Pharmacy
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 341-343 (18 ref.)
Keywords: Plant Leaves-chemistry; Diabetes Mellitus, Experimental; Cucurbitaceae; Rats, Wistar; Hypoglycemic
Agents-pharmacology
Abstract: The leaf of Telfairia occidentalis has been found to possess hypoglycemic or antihyperglycemic effect. The
hypoglycemic principle of the leaf is yet to be isolated. The aim of this study is to evaluate the hypoglycemic activity of
some fractions of ethanolic leaf extract of Telfairia occidentalis in rat as a step toward activity directed isolation of the
hypoglycemic component. Ethanolic leaf extract was successively extracted with ethyl acetate, butanol and ethanol to
obtain ethyl acetate, butanol and ethanol fractions [I-III]. The residue was taken as fraction IV. 250 mg/kg of the various
extracts were orally administered to normoglycaemic and alloxan-induced diabetic albino rats. Blood glucose
concentration was evaluated at 0, 1, 2 and 4 hours after treatment with One Touch glucometer. None of the fractions
reduced glucose concentration in the normoglycaemic rats, while only ethyl acetate fraction lowered glucose
concentration significantly at 2 and 4 hours [49.7 and 39.0%] compared to control value of 74.9 and 69.7%,
respectively, in the diabetic rats. The results showed that the hypoglycemic component of the ethanolic leaf extract of
the plant is contained in the ethyl acetate fraction.
Plant Gums
administration and dosage
Investigation and comparison of colon specificity of novel polymer khaya gum with guar gum.
Prabhu, Prabhakara; Ahamed, Nissara; Matapady, Harish Nairy; Ahmed, Mohd. Gulzar; Narayanacharyulu, R.;
Satyanarayana, D.; Subrahmanayam, E.V.S.
E-mail:[email protected]
NGSM Institute of Pharmaceutical Sciences - Department of Pharmaceutics
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 259-265 (11 ref.)
Keywords: Polymers-administration and dosage; Colon-metabolism; Meliaceae; Budesonide-administration and
dosage; Galactans-administration and dosage; Rabbits; Rats; Tablets; Drug Carriers
Abstract: To investigate the colon specificity of novel natural polymer khaya gum and compare with guar gum.
Release profile of tablets was carried out in presence and absence of rat cecal contents. The fast disintegrating core
tablets of budesonide, were initially prepared by direct compression technique. Later, these tablets were coated with
khaya gum or guar gum. After suitable pre compression and post compression evaluation, these tablets were further
coated using Eudragit L-100 by dip coating technique. X-ray images were taken to investigate the movement, location
and the integrity of the tablets in different parts of gastro intestinal tract in rabbits. The release profiles revealed that
khaya gum or guar gum, when used as compression coating, protected the drug from being released in the upper parts
of the gastro intestinal tract to some extent but the enteric coated formulations completely protected the drug from
being released in the upper parts of the gastro intestinal tract, and released the drug in the colon by bacterial
degradation of gums. It was found that both the polysaccharide polymers exhibited different release profiles in
presence and absence of rat cecal contents. However, further enteric coat helped in targeting the drug to colon very
effectively. Better dissolution models revealed the colon specificity of polysaccharides and alone can not be used either
for targeting the drug to the colon or for sustaining or controlling the release of drug.
Plants, Medicinal
Organosulfur compounds and possible mechanism of garlic in cancer.
Omar, S.H.; Al Wabel, N.A.
E-mail:[email protected]
Al Qassim University - College of Pharmacy
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SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 51-58 (82 ref.)
Keywords: Garlic; Sulfur Compounds-pharmacology; Anticarcinogenic Agents-therapeutic use; Neoplasmsprevention and control; Anticarcinogenic Agents-pharmacology
Abstract: Garlic [Allium sativum], a member of the family Liliaceae, contains an abundance of chemical compounds
that have been shown to possess beneficial effects to protect against several diseases, including cancer. Evidence
supports the protective effects of garlic in stomach, colorectal, breast cancer in humans. The protective effects appear
to be related to the presence of Organosulfur compounds, predominantly allyl derivatives, which also have been shown
to inhibit carcinogenesis in forestomach, esophagus, colon, mammary gland and lung of experimental animals. The
exact mechanisms of the cancer-preventive effects are not clear, although several hypotheses have been proposed.
Organosulfur compounds modulate the activity of several metabolizing enzymes that activate [cytochrome P450s] or
detoxify [glutathione S-transferases] carcinogens and inhibit the formation of DNA adducts in several target tissues.
Antiproliferative activity has been described in several tumor cell lines, which is possibly mediated by induction of
apoptosis and alterations of the cell cycle. Organosulfur compounds in garlic are thus possible cancer-preventive
agents. Clinical trials will be required to define the effective dose that has no toxicity in humans.
Scrutinizing the aqueous extract of leaves of Pedalium murex for the antiulcer activity in rats.
Banji, David; Singh, Jaideep; Banji, Otilia J.F.; Shanthamurthy, M.
E-mail:[email protected]
Nalanda College of Pharmacy - Department of Pharmacology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 295-299 (29 ref.)
Keywords: Plant Extracts-pharmacology; Phytotherapy; Anti-Ulcer Agents-pharmacology; Rats
Abstract: Peptic ulcer is manifested largely due to an alteration in lifestyle and diet. The antiulcer efficacy of the
aqueous extract of leaves of Pedalium murex on ethanol induced gastric lesions was investigated in our studies. This
has been substantiated by ascertaining the content of total acid, acid volume, total protein, ulcer index and glutathione.
Ulceration was induced in 36 hours fasted rats by the administration of 80% ethanol [1ml/kg] orally. The reference
standard [famotidine, 3mg/kg] and aqueous extract of leaves of Pedalium murex in doses of 50, 100, 200mg/kg was
given to different groups, one hour before the administration of ethanol. Marked gastric mucosal lesions were observed
with ethanol. A perceptible elevation in ulcer index, total acidity, acid volume, total protein and diminution of glutathione
was observed. Pretreatment with aqueous extract of leaves of Pedalium murex particularly at a dose of 200mg/kg in a
single schedule and 100mg/kg for 15 and 30 days treatment annihilated these alterations and elevated the level of
glutathione. Therefore the aqueous extract of leaves of Pedalium murex could be regarded as a favorable
antiulcerogen which could be attributed to its content of flavonoids and mucilage.
toxicity
Assessment of acute toxicity and reproductive capability of a herbal combination.
Riaz, Azra; Khan, Rafeeq Alam; Ahmed, Shadab; Afroz, Syeda
University of Karachi - Faculty of Pharmacy - Department of Pharmacology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 291-294 (39 ref.)
Keywords: Reproduction-drug effects; Phytotherapy; Lethal Dose 50; Fertility; Pregnancy; Mice
Abstract: The drug under investigation is an herbal combination of Withania somnifera, Tribulus terrestris, Mucuna
Pruriens and Argyreia speciosa which has been used for several years of its bio-stimulating, revitalizing and fertility
enhancing effects. Present preclinical study is specifically designed to access the safety and efficacy of the product.
The result of acute oral toxicity reveals that product is safe up to the dose of 5000mg/kg. The effects of study related to
reproductive capability of drug on both sex reveals increase in reproduction rate up to two generations i.e. F0 and F1.
Polycystic Ovary Syndrome
Leptin levels in relation to marital status and neuroendocrine function in Iraqi females with
polycystic ovary syndrome.
Khalaf, Ban H.
Al Mustansriya University - College of Pharmacy - Department of Pharmacotherapy
SPJ - Saudi Pharmaceutical Journal 2010; 18 (1): 41-44 (34 ref.)
Keywords: Leptin-blood; Luteinizing Hormone-blood; Follicle Stimulating Hormone-blood; Prolactin-blood; Marital
Status
Abstract: The present study was designed to evaluate the relationship between serum leptin levels and the
hormones related to fertility in Iraqi females with polycystic ovary syndrome [PCOS] and marital status. This study was
conducted during the period from July to December 2007. Twenty-four women [12 married and 12 unmarried] with
PCOS and not maintained on any type of therapy were included in the study. Twelve healthy and normal ovulatory
women with an age range matched with that of PCOS women were included. After an overnight fasting, blood samples
were drawn from all women at random days. While in those with regular menstrual cycles, blood samples were
obtained during the follicular phase of the cycle, except for samples utilized for the assay of progesterone that
performed in the day 21 of the cycle [luteal phase]. After preparation of serum, the levels of leptin, luteinizing hormone
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[LH], follicle-stimulation hormone [FSH], progesterone, testosterone and prolactin were analyzed. Both groups of
PCOS patients showed significantly lower levels of serum leptin, while prolactin, LH and FSH and testosterone were
significantly elevated compared to controls. No significant differences were reported among PCOS patients with
different marital status. In conclusion, impaired plasma leptin levels in PCOS women were associated with impaired
endocrinological parameters related to fertility.
drug therapy
Comparison of metformin and cyproterone-estrodiol compound effect on hs C-reactive protein
and serum androgen levels in patients with poly cystic ovary syndrome.
Aghamohammadzadeh, Nasser; Aliasgarzadeh, Akbar; Baglar, Leila; Abdollahifard, Seddigheh; Bahrami, Amir;
Najafipour, Farzad; Niafar, Mitra
Tabriz University [Medical Sceneries] - School of Medicine - Department of Endocrinology
Pakistan Journal of Medical Sciences 2010; 26 (2): 347-351 (26 ref.)
Keywords: Metformin; Cyproterone Acetate; C-Reactive Protein-drug effects; Androgens-blood; Drug Combinations;
Estradiol-analogs and derivatives
Abstract: The aim of this study was comparison of the effects of Metformin and Cyproterone-estradiol compound on
serum androgens and highly sensitive C-reactive protein levels. Sixty patients with Poly Cystic Ovary Syndrome
[PCOS] were enrolled in this study conducted during a period of 16 months from December 2004 to March 2006. Thirty
subjects were in each group and treated with Metformin one gram per day or Cyproterone-estradiol compound 21 days
monthly and at the beginning and after 3 and 6 months, weight, height, testosterone, dehydroepiandrosterone sulfate
[DHEA-S] and hs-CRP levels were measured. Mean age of patients was 23.5 +/- 8.7 years with the range of 15 to 49
years. In both groups significant decreases in DHEA-S levels and in Cyproterone-estradiol compound group a
significant decrease in testosterone levels were seen after 6 months, but there were no significant decrease on hsCRP levels. Comparison of two groups showed that there were no significant differences in the effects of these two
drugs on serum testosterone, DHEA-S and hs-CRP levels. In our study the level of hs-CRP at the beginning of
treatment were significantly higher in patients who were overweight and obese. Also we found that Cyproteroneestradiol compound causes significant decrease at the level of hs-CRP in overweight and obese patients. The results
of this study are different from those of previous studies about beneficial effects of Metformin on hs-CRP levels but are
similar to the results of studies that revealed probably obesity and overweight has important role in inducing
inflammation and increasing CRP levels.
Polyps
pathology
Location, size and clinical symptoms of uterine polyps.
Barati, M.; Masihi, S.; Ilkhan, S.
E-mail:[email protected]
Imam Khomayni Hospital - Department of Obstetrics and Gynecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 380-383 (9 ref.)
Keywords: Polyps-diagnosis; Uterus-pathology; Hysteroscopy; Metrorrhagia-diagnosis; Cross-Sectional Studies
Abstract: In this study we tried to find relationship between location, size and clinical symptoms of uterine polyps.
Our cross sectional study was performed during the year 2008 in Ahwaz Imam Khomayni Hospital. Patients who
underwent office hysteroscopy were evaluated and those with hysteroscopic diagnosis of polyp were entered in the
study. Hysteroscopic findings of location and size of polyps and clinical presentations of Abnormal Uterine Bleeding
[AUB] dysmenorrhea, infertility, discharge, spotting plus discharge were evaluated. One hundred and twenty four
patients were evaluated. The most common location of polyp and clinical presentation were cervical canal and AUB,
respectively. Polyp sizes of equal or less than 1 cm are commonly seen in cervical canal and cornea and more than 1
cm polyps are commonly found in uterine cavity and near internal os. In this study we showed that location of polyp is
important in clinical presentation. Patients presented with AUB had polyps more common in uterine cavity, patients
with spotting plus discharge had polyps more in cervical canal.
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Postoperative Hemorrhage
prevention and control
Reducing post operative bleeding after tonsillectomies in children by modifying the monopolar
diathermy technique: a study of 1500 patients.
Gooda, M. Rafique; Sheikh, Irshad; Suleri, Azam
E-mail:[email protected]
Hamdard University - Hamdard College of Medicine and Dentistry - Department of ENT and Head and Neck Surgeon
Pakistan Journal of Medical Sciences 2010; 26 (2): 434-437 (25 ref.)
Keywords: Tonsillectomy; Diathermy-methods; Prospective Studies
Abstract: To evaluate the effects of modifications of the present technique of monopolar diathermy tonsillectomy on
the incidence of post operative bleeding and compare them with international data for tonsillectomies done without
modifications. This is a prospective, longitudinal experimental study. Fifteen hundred patients were studied from
January 2000 to January 2008. Patient's age ranged from five to fifteen years. All patients underwent tonsillectomies
by modified monopolar diathermy method. The incidence of postoperative bleeding was assessed. Two patients
developed significant secondary haemorrhage, which is defined as requiring a return to the operating theater for the
control of bleeding. One patient with secondary bleed required blood transfusion in addition to a return to the operating
theater. Five patients developed minor secondary bleed that was controlled by conservative means. Two patients
developed reactionary bleeding that was controlled in the operating room before return of the patient to the bed.
Modifications in the existing technique produces a significantly lower incidence of post operative bleeding from the
tonsillar fossae and compares well than those reported in the international literature.
Postpartum Hemorrhage
prevention and control
Simple technique of uterine compression sutures for prevention of primary postpartum
hemorrhage during caesarian section.
Nahar, Shamsun; Nargis, Shamim Fatema; Khannam, Merina
E-mail:[email protected]
Victory Nursing and Infertility Management Centre - Department of Obstetrics and Gynaecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 319-323 (11 ref.)
Keywords: Suture Techniques; Sutures; Cesarean Section; Treatment Outcome
Abstract: To report our clinical experience of the effect of applying simple technique of uterine compression sutures
to prevent primary postpartum hemorrhage in atonic uterus developed during caesarian section. The use of simple
uterine compression sutures in atonic uterus during caesarian section was reviewed within the period of January 2006
to March 2008 in a tertiary obstetric unit in three Medical College. It is a descriptive observational study. In atony
uterus, first to treat fundal compression, used Intravenous or Intramuscular uterotonic drugs followed by per-rectal use
of misoprostol and observed 10-15 minutes and then applied simple technique of uterine compression sutures. Age of
patients ranged from 15-40 years. 49 patients were primiparae and 54 patients were multiparae. Indications for
caesarian section were previous caesarian section 21 [20%], large baby head to disproportion 23 [22%], obstructed
labour and prolonged labour 29 [28%], twin pregnancy 16 [15.5%], polyhydromnios 4 [3.8%], abruptio placenta 4
[3.2%], placenta preavia accreta 7 [6.5%], All cases were maintained with post-operative 10 units oxytocin for 8 hours.
Two patients needed one unit blood transfusion after surgery. No post-operative excessive bleeding was observed.
There was no alteration of uterine involution and lochial discharge. In followed up cases subsequent pregnancy were
12 [11.6%]. Extreme degree of uterine compression may leads to uterine anatomic damage. Simple compression
technique is surgically easy, with life saving potential, offers relative safety, time saving and can be managed by
trainee doctors after some experience.
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PPAR gamma
agonists
Pioglitazone, a ppar-gamma ligand inhibited the nicotinamide streptozotocin induced sperm
abnormalities in type-2 diabetic wistar rats.
Rabbani, Syed Imam; Devi, Kshama; Khanam, Salma
Al-Ameen College of Pharmacy - Department of Pharmacology
Pakistan Journal of Pharmaceutical Sciences 2010; 23 (3): 326-331 (30 ref.)
Keywords: Spermatozoa-drug effects; Diabetes Mellitus, Type 2-metabolism; Niacinamide-toxicity;
Thiazolidinediones-pharmacology; Rats, Wistar; Streptozocin-toxicity
Abstract: Oxidative stress due to chronic hyperglycemia is known to cause infertility in diabetic patients. Pioglitazone
[PIO], a PPAR-gamma ligand is known to possess the antioxidant property however, its role on the oxidative stress
mediated germinal damage in Type-2 diabetes mellitus [T2DM] is poorly studies in the literature. In this study, the
effect of PIO [1 and 10 mg/kg, p.o. daily for 4 weeks] was evaluated against the nicotinamide [NA-230 mg/kg, ip] and
streptozotocin [STZ-65 mg/kg, ip] induced changes in sperm abnormality and antioxidant status in Wistar rats. The
effect of PIO on the male reproductive cells was studied by determining the sperm shape abnormality and sperm count
in the experimental T2DM. The antioxidant profile was studied by estimating the serum lipid peroxidation [LPO],
glutathione [GSH] and glutathione peroxidase [GPx] levels. The higher dose of PIO [10 mg/kg] significantly [P<0.001]
reduced the sperm shape abnormality and increased the sperm count [P<0.00l], besides decreasing [P<0.05] the LPO
and enhancing the GSH and GPx levels in the diabetic rats. However, the lower dose of PIO [1 mg/kg] produced
inhibitory [P<0.05] effect against the changes induced by T2DM in the sperm shape abnormality and GSH levels. alpha
tocopherol tested as alpha standard antioxidant agent prevented [P<0.001] the NA-STZ mediated alterations in sperm
abnormalities and antioxidant enzyme levels. The results suggest that the inhibitory effect of PIO against the 12DM
induced sperm abnormality could be related to its antioxidant property.
Pregnancy Outcome
The comparative study of pregnancy outcomes in primiparous and multiparous women with
increasing age.
Nooritajer, Maryam; Aghamohammadi, Azar
E-mail:[email protected]
Islamic Azad University Branch of Islamshahr - Faculty of Basic Sciences
Pakistan Journal of Medical Sciences 2010; 26 (2): 430-433 (13 ref.)
Keywords: Parity; Women; Age Factors; Retrospective Studies
Abstract: To compare the pregnancy outcomes in primiparous women and multiparous [more suitable word for our
population] women over 35 and below 35 years. This is a descriptive comparative study which enrolled 1021 pregnant
women and pregnancy outcomes were compared in 4 groups of primiparous and multiparous women over and below
35. To analyze the inputs using SPSS software, the 2 test, Fisher, Odds-Ratio and logistic regression with forward
method were used. In primiparous women, there is a statistically significant relation between the age over 35 and
preeclampsia, gestational diabetes, preterm labor, cesarean section and low birth weight. In multiparous women, there
is a significant relation between age of over 35, preeclampsia and low birth weight. In the women over 35 years parity
is effective on the measure of preeclampsia and cesarean delivery. Mother's increased age can be an independent
factor for pregnancy outcomes. The primiparous women are more likely to be affected by age. As a matter of fact the
aged women can have a natural vaginal delivery with a term infant and the over age mustnt be a contraindication for
pregnancy.
Pregnant Women
Beliefs and practices of Iranian pregnant mothers regarding vitamins and minerals.
Mashayekhi, S.O.; Dilmaghanizadeh, M.; Fardiazar, Z.; Bamdad Moghadam, R.; Ghandforoush Sattari, M.
E-mail:[email protected]
National Public Health Management Centre - Department of Pharmacology and Toxicology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 203-207 (26 ref.)
Keywords: Vitamins; Minerals; Health Education; Culture; Questionnaires
Abstract: The objective of this descriptive study was to examine the vitamin and mineral supplements safety beliefs
and practices of Iranian pregnant women. Data were collected from 400 randomly chosen women. More than 50% of
the participants believed that taking vitamins and minerals during pregnancy was safe; 87% reported taking iron during
pregnancy; of which 71.7 % reported their doctor as the main recommender; 21.8% reported first trimester as the most
beneficial time for iron supplementation, 13.0% second trimester and 3.0% third trimester. Although an appropriate
intake of vitamins and minerals can assure health in pregnancy, excess can be harmful. Educational programmes for
women of childbearing age are necessary.
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Prenatal Care
Antenatal care in primary health care centres in Medina, Saudi Arabia, 2009: a cross-sectional
study.
Habib, F.; Hanafi, M.I.; El Sogheer, A.
Taibah University - College of Medicine - Department of Obstetrics and Gynaecology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 196-202 (29 ref.)
Keywords: Primary Health Care; Cross-Sectional Studies
Abstract: This study evaluated antenatal care [ANC] services for pregnant women attending primary health care
centres in Medina city, Saudi Arabia in 2009. A cross-sectional survey collected data on ANC tasks performed at visits
by 394 pregnant women attending 7 clinics. ANC was assessed in 3 domains: clinical assessment [at the initial visit
and return visit], health promotion and care provision. The mean duration of initial visits was 10.3 [SD 2.3] minutes and
of return visits was 9.1 [SD 1.1] minutes. Overall performance on ANC tasks was fair. The significant predictors of ANC
performance of tasks were: size of population served per centre; presence of more than 1 physician carrying out ANC
at the centre; physician's age, mother tongue, nationality and qualifications; and woman's education and employment
status. Having more physicians available for ANC in primary care centres could improve the standard of care.
psychology
Antenatal care seeking behaviour among slum mothers: a study of Rajshahi city corporation,
Bangladesh.
Rahman, Mahfuzar; Islam, Rafiqul; Rahman, Mosfequr
University of Rajshahi - Department of Population Science and Human Resource Development
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 50-56 (15 ref.)
Keywords: Behavior; Mothers; Poverty Areas; Immunization Programs-utilization
Abstract: The study aimed to identify the important effects of some selected variables in antenatal care [ANC]
seeking behaviour among slum mothers. The data for the study were collected in 2006 from 700 mothers in the slum
areas of Rajshahi City Corporation [RCC], Bangladesh. The results indicate that tetanus toxoid [TT] is relatively
widespread in slum areas of RCC. Serious health implications were observed for the mothers and their children who
lived in the study areas because more than half of the respondents [56.1%] were not assisted at their last childbirth by
any health professional. The respondents were too poor to buy iron tablets/syrup and vitamin tablets/syrup during their
last pregnancy. The application of a logistic regression model suggested that demographic and socio-economic factors
were associated with ANC seeking behaviour among slum mothers. Respondents' education, place of treatment,
husband's occupation, family's income, and exposure to mass media had highly significant effects on mothers seeking
medical checkups during their last pregnancy.
Publications
A comparative analysis of writing scientific references manually and by using endnote
bibliographic software.
Skaik, Younis Abed Al Wahhab M.
E-mail:[email protected]
Al Azhar University - Faculty of Applied Medical Sciences - Department of Laboratory Medicine
Pakistan Journal of Medical Sciences 2010; 26 (2): 498-499 (3 ref.)
Keywords: Writing; Databases, Bibliographic; Authorship; Information Systems; Handwriting; Correspondence as
Topic
standards
Publication audit for the year 2009 and revised guidelines for authors of Pakistan Journal of
Medical Sciences.
Jawaid, Shaukat Ali
E-mail:[email protected]
Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences 2010; 26 (2): 500-502 (4 ref.)
Keywords: Management Audit; Journalism, Medical; Authorship
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Purkinje Cells
Effects of sodium nitrite-induced hypoxia on cerebellar Purkinje cells in adult rats.
Zaidi, Zeenat F.
E-mail:[email protected]
King Saud University - Faculty of Medicine - Department of Anatomy
Pakistan Journal of Medical Sciences 2010; 26 (2): 261-266 (38 ref.)
Keywords: Hypoxia, Brain; Sodium Nitrite; Rats
Abstract: To explore the changes in Purkinje cells in adult rats after inducing chemical hypoxia by sodium nitrite
Adult male albino rats, weighing 180-200 gm were used in this study. The animals were fasted for three hours prior to
drugs administration. One hour after sodium nitrite [75 mg/kg] subcutaneous injection, rats were decapitated. The
brains were removed and placed overnight in fixative containing 10% formalin. Cerebellum were paraffin-embedded for
hematoxylin and eosin staining and cut at 5 micro m in the coronal plane. Fifty Purkinje cells along the line of cells from
two randomly chosen portions of each section were counted at a magnification of x20. Cells in a total of five sections
were counted to compute the ratio of damaged cells to intact neurons. There was no marked difference in the general
appearance and thickness of the cerebellar cortices of the control and the sodium nitrite treated rats. The principal
findings in the treated group were that almost all the Purkinje cells showed autolytic changes. Their arrangement as a
single layer was also deranged in certain areas. Some areas showed complete loss of Purkinje neurons. Sodium
nitrite-induced hypoxia results in severe damage to the Purkinje neurons.
Referral and Consultation
Re: the trend to seek a second opinion abroad among cancer patients in Oman: challenges and
opportunities.
Chopra, Pradeep
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Surgery
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 276-277 (2 ref.)
Keywords: Neoplasms; Family
Retinal Vein Occlusion
drug therapy
Early avastin management in acute retinal vein occlusion.
Mehany, Shaaban A.; Mourad, Khaled M.; Shawkata, Ahmad M.; Sayeda, Mohammed F.
El-Minia University - El-Minia Faculty of Medicine - Department of Ophthalmology
Saudi Journal of Ophthalmology 2010; 24 (3): 87-94 (39 ref.)
Keywords: Antibodies, Monoclonal-therapeutic use; Treatment Outcome; Prospective Studies
Abstract: To evaluate the safety, functional and anatomical effects of intravitreal Avastin [bevacizumab] in treatment
of recent retinal venous occlusion. Prospective interventional series non-comparative study. Department of
Ophthalmology, Faculty of Medicine, El-Minia University, Egypt. The study included 30 eyes of 30 patients with recent
retinal venous occlusion of less than 3 months duration 12 eyes [40%] of patients with central retinal vein occlusion
[CRVO] and 18 eyes [60%] with branch retinal vein occlusion [BRVO] were injected with intravitreal bevacizumab 1.25
mg [0.05 ml] of commercially available bevacizumab [Avastin; Genentech, Inc., San Francisco, CA] at a concentration
of 25 mg/ml as a primary treatment. The mean number of injections was 2.7 [range, 1-6 injections] 6-8 weeks intervals
and follow-up for 12 months [range, 913 months]. Patients underwent visual acuity testing [VA] as functional
assessment. Anatomically, optical coherence tomography [OCT] is used for measurement of central retinal thickness
[CRT] to detect macular edema [ME], fundus photography and fluorescein angiography [FA] to detect venous
tortuosity, optic disc edema and surface wrinkling rather than ME. All finding at baseline and each follow-up visit were
reported. The mean age of all patients was 65.3 years +/- 8.5 [range, 55-82 years], 20 males and 10 females patients.
The mean baseline VA was 20/240 [log MAR 1.08 +/- 0.52] and improved to 20/60 [log MAR 0.48 +/- 0.32] with
statistically significance difference change [P<0.001]. The mean baseline CRT was 455 micro m +/- 126 [range,
386510], decreased to 356 micro m +/- 118 [range, 296-416] after 1 month with statistically significance difference
change [P<0.02] and to 402 micro m +/- 170 [range, 338-468] after 6 months [P<0.067] and to 250 micro m +/- 48
[range, 200298] at last follow-up with statistically significance difference change from the baseline [P<0.001]. There
were great proportional decrease in venous tortuosity, optic disc edema and surface wrinkling after 1 month of
injection. Neither systemic nor intraocular adverse events were reported. Intravitreal Avastin [IVA] is safe well tolerated,
effectively improve VA, fundus picture and stabilize anterior segment neo-vascular activity in patients with recent retinal
venous occlusion.
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Retinoblastoma
ultrasonography
Ultrasonography in diagnosis of retinoblastoma.
Arif, Muhammad; Kundi, Niamat Ullah Khan
E-mail:[email protected]
Kust Institute of Medical Sciences - Department of Ophthalmology
PJMR - Pakistan Journal of Medical Research 2010; 49 (1): 18-20 (11 ref.)
Keywords: Retinoblastoma-diagnosis; Early Detection of Cancer; Tomography, X-Ray Computed
Abstract: Retinoblastoma is a common childhood malignant intraocular tumor. Early detection and urgent treatment
enhances survival in terms of sight and life. Ultrasonography has emerged as an indispensable tool for its examination
and diagnosis. To evaluate the reliability of ophthalmic Ultrasonography as a diagnostic tool for retinoblastoma in
children. Eye [A] unit department of Ophthalmology, Khyber Teaching Hospital, Peshawar, Pakistan, from January,
2007 to January, 2009. Patients with suspected clinical features of retinoblastoma were admitted in referral center for
retinoblastoma. After recording history, patients underwent investigations which included Ultrasonography later
supported by examination under anesthesia and C.T Scan orbit and brain. Treatment was offered following initial
diagnosis. A total of 25 children were initially diagnosed as retinoblastoma and were admitted in Eye [A] unit during the
last 2 years. There were 16 males and 9 females. There were 16 unilateral and 9 bilateral cases. On ophthalmic
Ultrasonography, out of 34 eyes [25 patients], 33 [97%] revealed calcification and high reflectivity. Later a C.T Scan
orbit and brain was also done. Histopathological confirmation was carried out in 17 enucleated eyes of 25 patients;
where 9 patients had bilateral disease, 4 specimens were lost and 4 patients had intracranial extension and therefore
enucleation was not advised in this group. Ophthalmic ultrasound is an easy, reliable and non invasive method for the
diagnosis of retinoblastoma.
Rh-Hr Blood-Group System
genetics
Non-invasive prenatal determination of fetal rhd genotyping from maternal plasma: a preliminary
study in Pakistan.
Mohammed, Nuruddin; Kakal, Fatima; Somani, Mehreen; Zafar, Wajiha
E-mail:[email protected]
The Aga Khan University Hospital - Department of Obstetrics and Gynaecology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 246-249 (20 ref.)
Keywords: Prenatal Diagnosis; Fetus; Genotype; Mothers; Plasma; Cross-Sectional Studies; Reverse Transcriptase
Polymerase Chain Reaction
Abstract: To determine the accuracy of the non-invasive pre-natal real-time polymerase chain reaction based fetal
RhD genotyping from maternal plasma. Cross-sectional study. Juma Health Sciences Research Laboratory, The Aga
Khan University Hospital, Karachi, from July to December 2008. Cell-free plasma DNA from 21 D-negative women with
D-positive spouse between 20-39 weeks of gestation was tested for the presence of exon 5 region of RhD gene using
real-time polymerase chain reaction. beta-globin was employed as the house-keeping gene. Sensitivity and specificity
of the real-time PCR-based non-invasive fetal RhD genotyping was obtained by calculating proportion of the D-positive
fetuses that were D-positive at birth as well. Of the 21 D-negative women 13 and 8 neonates were determined to be Dpositive and D-negative, respectively, by serologic studies on cord blood samples at birth. RhD status was correctly
determined in 17 of 21 cases. There were three false-positive and one false-negative results. The sensitivity and
specificity of the assay was 92.3% [95% Cl: 62.1, 99.6] and 62.5% [95% Cl: 25.9, 89.8], respectively. The positive and
negative predictive value of the assay was 80% [95% Cl: 51.4, 94.7] and 83.3% [36.5, 99.1], respectively. These
preliminary results demonstrate the feasibility of non-invasive pre-natal diagnosis of fetal RhD status of D-negative
mothers in Pakistan.
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Rhinitis, Allergic, Persnnial
therapy
Comparative study of efficacy of mucosal electrocautry versus submucosal diathermy for the
treatment of inferior turbinate hypertrophy of nose.
Chand, Gian; Kumar, Sanjay; Khemani, Asudo Mal
E-mail:[email protected]
Sindh Government Hospital - Department of ENT
Pakistan Journal of Medical Sciences 2010; 26 (2): 454-457 (10 ref.)
Keywords: Hypertrophy; Treatment Outcome; Turbinates-pathology; Rhinitis, Vasomotor-therapy; Retrospective
Studies; Diathermy; Electrocoagulation
Abstract: To compare the efficacy of submucosal electrocautry versus submucosal diathermy for the surgical
treatment of inferior turbinate hypertrophy of nose and to analyze the outcome of both treatment options. Retrospective
study was done in 100 cases at the department of otorhinolaryngology, head and neck surgery department JPMC and
PMCH Nawabshah, form January 2007 to July 2008. The patients suffering from inferior turbinate hypertrophy were
included in this study having ages between 20 to 35 years. Demographic data were obtained from the patient files at
the Hospital and were complied for result. Among one hundred patients which were evaluated and surgically treated,
30 cases were of allergic rhinitis, 28 cases of vasomotor rhinitis, 22 cases were of chronic hypertrophic rhinitis and rest
of 20 cases had mild septal deviation. The results were evaluated for the patients, pre-, post-operative symptoms and
clinical findings. Submucosal diathermy was found more successful in relieving the patients' symptoms and decreasing
the size of the inferior turbinates as compared to mucosal electrocautry.
Rhinitis, Allergic, Seasonal
drug therapy
Montelukast versus nigella sativa for management of seasonal allergic rhinitis: a single blind
comparative clinical trial.
Ansari, Munawar Alam; Ansari, Noor Alam; Junejo, Sameen Afzal
E-mail:[email protected]
Liaquat University of Medical and Health Sciences - Department of Pharmacology and Therapeutics
Pakistan Journal of Medical Sciences 2010; 26 (2): 249-254 (23 ref.)
Keywords: Nigella Sativa; Phytotherapy; Quinolines-therapeutic use; Treatment Outcome
Abstract: To compare the therapeutic role of leukotriene receptor blocker Montelukast with N. Sativa seeds in
seasonal allergic rhinitis patients. Comparative uncontrolled single blind clinical assessment was carried out over forty
seven untreated adult patients torment from seasonal allergic rhinitis and staring for outpatient management. All
patients were chosen from different primary care health centers, registered and were divided in a single-blind approach
to obtain Montelukast, 10 mg/day, group I [n=24] and 250 mg/day of N. Sativa, group II [n=23] orally for two weeks.
Patients joined-up the study has completed the therapeutic plan. Montelukast and N. Sativa both demonstrated a
significant and early decrease in daytime as well as ophthalmic symptoms, while montelukast showed diminished and
late effects on nighttime symptoms when compared with N. Sativa. In addition montelukast has also been showing to
cause drug allied side effects like headache, dizziness and heart burn. It would come into view that N. Sativa is safe
and thoroughly free from threat of adverse effects. So it is a liable management alternative for seasonal allergic rhinitis
patients.
Schistosomiasis
history
[Schistosomiasis in Morocco: from discovery to after elimination].
Barkia, H.; Barkia, A.; Nhammi, H.; Belghyti, D.
E-mail:[email protected]
Ibn Tofail University - Research Unit for Comparative Parasitology - Laboratories for Biology and Parasitology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 250-256 (10 ref.)
Keywords: Schistosomiasis-prevention and control; Schistosomiasis-transmission
Abstract: This paper outlines the history of schistosomiasis in Morocco and the efforts made to eliminate it from the
country. Since it was first diagnosed in 1914 in Marrakesh, schistosomiasis remained for decades a public health
76
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problem in Morocco. A national control programme was launched in 1982 and it led to a considerable reduction in the
incidence and morbidity associated with the disease. Consequently, the programme shifted from disease control to an
elimination process launched in 1994. This process aimed to eliminate the disease transmission by the end of 2004
and has helped to clear all known foci. Today, the challenge is to maintain schistosomiasis elimination and to be
certified schistosomiasis-free by the World Health Organization.
Schools, Medical
Afghanistan and Oman: personal reflections on a profound contrast.
Foster, Ken
E-mail:[email protected]
Kabul General Hospital
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 144-147 (7 ref.)
Keywords: Education, Medical; Learning; Geography; Delivery of Health Care
How do we define a medical school?: reflections on the occasion of the centennial of the Flexner
Report.
Karle, Hans
E-mail:[email protected]
Health Sciences Sultan Qaboos University - College of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 160-168 (20 ref.)
Keywords: Education, Medical; Privatization
Abstract: A century after the Flexner Report on medical education in North America, which revolutionised the training
of medical doctors all over the world, it is time to revisit this famous document and analyse symptoms and signs of a
return to pre-Flexnerian conditions. With the ongoing mushroom growth over the last decades of small, proprietary
educational institutions of low quality and driven by for-profit purposes, medical education is in a threatened position.
This trend is of general international interest because of the increasing migration of medical doctors. There is a need
for discussion of what should be the rational criteria and basic requirements for establishing new medical schools.
Sepsis
epidemiology
Incidence of late onset neonatal sepsis in very low birth weight infants in a tertiary hospital: an
ongoing challenge.
Al Faleh, Khalid M.
E-mail:[email protected]
King Saud University - King Khalid University Hospital - Neonatal Intensive Care Unit
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 227-230 (13 ref.)
Keywords: Infant, Newborn; Infant, Very Low Birth Weight; Incidence; Age of Onest; Hospitals; Incidence
Abstract: Late onset neonatal septicaemia [LONS] is one of the major causes of morbidity and mortality in very low
birth weight [VLBW] infants. The main objective of this study was to investigate the rate of LONS in the Neonatal
Intensive Care Unit [NICU] of King Khalid University Hospital [KKUH] in Riyadh, Saudi Arabia over a three year period
and compare it to international standards. To determine the incidence of LONS, a retrospective study was undertaken
and premature infants with a birth weight less than 1250 g were included, giving a total of 273 infants. Their bacterial
profile and the antimicrobial susceptibility of the isolates were investigated, and the changes in trends over the study
period studied. 91.5% of included infants [217/237] had 1 or more blood cultures obtained beyond the second day of
life. 41% [98/237] of included infants had at least one episode of proven sepsis. The majority [71.4%] of first episode
sepsis was caused by Gram-positive organisms. Coagulase negative Staphylococcus accounted for around 80% of all
Gram-positive infections. Gram-negative pathogens accounted for 24.5% of the late onset infections while fungal
organisms were responsible for 4%. The rate of LONS was high and exceeded internationally reported rates in our
tertiary care NICU. Gram-positive organisms continue to be major causative isolates. High priority should be placed on
preventative steps to control nosocomial sepsis.
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Skin Diseases, Vesiculobullous
diagnosis
Use of direct immunofluorescent microscopy in the diagnosis of vesiculobullous disorders of
skin.
Rizvi, Shoaib Raza; Sadiq, Saleem
E-mail:[email protected]
Sindh Institute of Urology and Transplantation - Department of Histopathology
Pakistan Journal of Medical Sciences 2010; 26 (2): 411-415 (16 ref.)
Keywords: Fluorescent Antibody Technique, Direct; Retrospective Studies
Abstract: To determine the relative frequencies of various vesiculobullous disorders of skin in our patients and the
morphological and direct immunofluorescent patterns of these disorders. This retrospective study was carried out in the
Department of Pathology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi, Pakistan on
all the cases of vesiculobullous disorders of skin diagnosed in the department from January 2002 to June 2007. All the
skin biopsies received during the study period were reviewed and cases of vesiculobullous disorders were selected for
detailed study. Direct immunofluorescent [DIF] staining was done on these cases using fluorescein isothiocyanate
conjugate [FITC] labelled antibodies for IgG, IgA, IgM, C3c and Fibrinogen. The data was analysed statistically using
SPSS software. A total of 62 DIF proven cases of vesiculobullous disorders of skin were studied. Pemphigus vulgaris
[PV] was found to be the most frequent disorder [32.25%] followed by bullous pemphigoid [BP] with a frequency of
27.42%. The relative frequencies of pemphigus foliaceus [PF], dermatitis herpetiformis [DH], childhood bullous
pemphigoid [CBP] and chronic bullous dermatosis of childhood [CBDC] were 20.96%, 6.45%, 4.83% and 6.45%
respectively. One case each of IgA pemphigus [IgAP] and herpes gestationis [HG] were seen. IgA pemphigus can only
be diagnosed after having observed the immunofluorescence pattern of this disorder. Definitive diagnosis of certain
blistering lesions of skin requires the DIF microscopy. However, in special circumstances it needs to be reinforced with
either salt split skin technique or immune electron microscopy.
Smoking
epidemiology
Prevalence and correlates of tobacco use among grade 8-10 students in Peshawar, Pakistan.
Shaikh, M.A.; Hunt, B.P.
E-mail:[email protected]
Independent Consultant
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (2): 180-181 (4 ref.)
Keywords: Prevalence; Students; Tobacco Use Disorder-epidemiology
[Tobacco: its control is urgently needed].
Kinj, Nadeem
E-mail:[email protected]
American University Hospital
LMJ - Lebanese Medical Journal 2010; 58 (2): 122-124
Keywords: Smoking-prevention and control; Awareness; Smoking Cessation; Developing Countries
Abstract: Smoking is a chronic disease that kills five million yearly. Nicotine is responsible for the addictive part.
Smoking is quite neglected, due to its predominance in poor and underdeveloped countries. Available smoking
cessation programs have a limited role to play. Fighting tobacco dependence requires a multidisciplinary approach
involving awareness campaigns, enforcing no smoking laws in public places, raising taxes and careful watching of our
kids not to get addicted.
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Snake Venoms
history
Could deadly snake venom save lives?
Banerjee, Yajnavalka; Bayoumi, Riad; Farook, Seyad M.S.
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Biochemistry
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 142-143 (2 ref.)
Keywords: Snake Venoms-therapeutic use; Captopril-history
Somatoform Disorders
The concept of somatisation: a cross-cultural perspective.
Al Busaidi, Zakiya Q.
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Family Medicine and Public Health
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 180-186 (47 ref.)
Keywords: Cross-Cultural Comparison; Review Literature as Topic; International Classification of Diseases;
Diagnostic and Statistical Manual of Mental Disorders
Abstract: Somatisation is generally defined as the tendency to experience psychological distress in the form of
somatic symptoms and to seek medical help for these symptoms, which may be initiated and/or perpetuated by
emotional responses such as anxiety and depression. Somatisation has been recognised as a commonly encountered
problem, especially in primary health care, contributing to frequent use of medical services and to frustration in both the
patient and the doctor. In recent years, there has been a great deal of dissatisfaction with the terminology and
classification of somatisation, and the way this definition is applied to non-Western cultures. This dilemma pertains to
different aspects of the definitions, mainly their usefulness, adequacy and applicability. This article aims to review the
literature on the development of the concept of somatisation and how this definition is applied from a cross-cultural
aspect.
Soybeans
Effect of soybean diet on serum lipids an lipoproteins of postmenopausal women.
Ghafarzadeh, Masoumeh; Namdari, Mehrdad
E-mail:[email protected]
Lorestan University of Medical Sciences - Department of Gynecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 407-410 (15 ref.)
Keywords: Diet; Lipids-blood; Lipoproteins-blood; Postmenopause; Women
Abstract: To investigate the effect of soybean on serum lipids and lipoproteins in hypercholesterolemic
postmenopausal women. One hundred participants were included and divided randomly into two arms. One arm
received two grams of soy every day, while the other group received similar shaped capsules filled with placebo.
Subjects and outcome assessors were kept blind to the contents of the capsules. Serum cholesterol, triglyceride and
low-and high-density lipoproteins were measured before and after the intervention. The two groups were similar in their
baseline characteristics. We observed no favorable changes in lipid profile in either of the two groups. The two arms of
the study responded similarly to the intervention and no statistically significant difference was observed between these
responses. This double-blind randomized controlled trial does not support the hypothesis that the use of soybean
improves serum lipid constituents in postmenopausal women having hypercholesterolemia.
Stomach
abnormalities
Pyloric duplication cyst: a rare congenital anomaly.
Rathore, Altaf Hussain; Hussain, Riaz; Rathore, Farhan
E-mail:[email protected]
Foundation Hospital
Pakistan Journal of Medical Sciences 2010; 26 (2): 494-496 (17 ref.)
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Keywords: Cysts-diagnosis; Cysts-surgery; Stomach-surgery
Abstract: Pyloric duplication cyst is one of the rarest congenital anomalies. We present such a case in a boy of 6-1/2
years old who was treated by us successfully. The theories of its embryogenesis, mode of presentations, diagnosis
and treatment are discussed.
Stress, Psychological
Stress in postgraduate trainee doctors of public and private Universities of Karachi.
Mumtaz, Yasmin; Jahangeer, Ashraf; Habib, Adnan; Adnan, Sara; Mumtaz, Zara
E-mail:[email protected]
Dow University of Health Science - Department of Community Medicine
Pakistan Journal of Medical Sciences 2010; 26 (2): 420-425 (20 ref.)
Keywords: Physicians; Universities; Cross-Sectional Studies; Teaching; Private Sector; Public Sector; Training
Support
Abstract: To evaluate and compare stress level of Postgraduate trainee doctors in public and private sector Medical
Universities. A comparative cross sectional study was conducted at Dow University of Health Sciences and Agha Khan
University Hospital Karachi among Postgraduate Medical trainee who are doing FCPS, MCPS, and DCPS from Jan.
2008-Dec. 2008. A total of 207 doctors were selected by non-probability convenience sampling technique. Main
outcome was major stress level of Medical trainees or resident. Out of the total 207 trainee doctors 62.3% were found
to be under stress. Proportion of females with stress was 66.3%. Most of the married PGs 67.2% had high stress level.
A large proportion almost 69.7% of doctors who were in stress belongeds to low income group. This study did not find
any statistical significance of stress with respect to different demographic and socioeconomic variable that were age,
gender, monthly income, specialty and university. The stress level of Postgraduate trainees in both the universities was
found to be high. The stress was found to be high among female trainees but no risk factor showed significant
association with stress. Every effort should be made to help the future healers in understanding the symptoms of stress
and ways to deal with it effectively and safely.
Stress in the medical profession and its roots in medical school.
Al Lamki, Lamk
Sultan Qaboos University - College of Medicineand health Sciences
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 156-159 (17 ref.)
Keywords: Schools, Medical; Medicine; Human
epidemiology
A comparative study of perceived stress among female medical and non-medical university
students in Dammam, Saudi Arabia.
Al Dabal, Badria K.; Koura, Manal R.; Rasheed, Parveen; Al Sowielem, Latifa; Makki, Suhair M.
E-mail:[email protected]
Dammam University - College of Medicine - Department of Family and Community Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 231-240 (18 ref.)
Keywords: Students, Medical; Students; Universities; Cross-Sectional Studies; Questionnaires
Abstract: The objective of this study was to investigate any differences between female undergraduate medical and
non-medical students for: 1] prevalence and causes of perceived academic stress, and 2] changes in physical, mental,
psychological and emotional health as well as life-style since starting college studies. A cross-sectional study was
conducted at Dammam University, Dammam, Saudi Arabia, in January 2008. All 319 pre-clinical female medical
students were included in the study and 297 non-medical students from the College of Applied Studies and Community
Services [CASCS] were selected by stratified random sampling. The study instrument was a questionnaire on the
"Influence of Studying on Students' Health". More medical students [48.6%] reported being frequently stressed due to
studies than CASCS students [38.7%, P <0.01]. Unsuitable teaching methods, an unsatisfactory study environment,
and fear of failure in examinations were more frequently mentioned by medical than non-medical students [P <0.05].
While underlying social problems were significantly more common in medical students, economic problems were more
prevalent among CASCS students [P <0.05, P <0.05]. More medical than non-medical students reported a worse
status of physical and mental health, anxiety and depression and negative life-style changes since initiation of the
college programme. Medical students were at higher risk of physical and mental health problems than non-medical
students due to academic stress. Since a substantial proportion of CASCS students also experienced academic stress,
we recommend that a student support committee be established for both colleges to provide counselling and guidance
in healthy ways to cope with stress.
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Strongyloidiasis
diagnosis
A case of gastric and duodenal strongyloidiasis.
Al Sajee, Dhuha M.A.; Al Hamdani, Aisha
E-mail:[email protected]
Sultan Qaboos University Hospital - Department of Pathology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 262-265 (7 ref.)
Keywords: Stomach-parasitology; Duodenum-parasitology; Strongyloides Stercoralis; Albendazole-therapeutic use
Abstract: Strongyloides stercoralis is a nematode parasite which causes a protracted asymptomatic intestinal
infection. It is considered a life threatening condition in immunocompromised patients when hyperinfection is
associated with disseminated disease. The diagnosis by routine stool examination is very limited since the larval output
in stools is very low. We present the case of a 52 year-old Omani man from Salalah, in the southern region of Oman,
with a 15-year history of type 2 diabetes mellitus and recently discovered to have hairy cell leukaemia, who complained
of nausea, abdominal pain, loss of appetite and loss of weight. An oesophagogastroduodoscopic biopsy was obtained
and histopathologic examination revealed gastrointestinal strongyloidiasis.
Students, Medical
[Health habits and vaccination status of Lebanese residents: are future doctors applying the
rules of prevention?]
Hage, Nasr C.; Sayegh, J.; Abi Rizk, G.
E-mail:[email protected]
University of Saint-Joseph [USJ] - Department of Family Medicine
LMJ - Lebanese Medical Journal 2010; 58 (2): 91-96 (31 ref.)
Keywords: Motor Activity; Life Style; Health Behavior; Vaccination-utilization
Abstract: There has never been a nationally representative survey of medical students' personal health-related
practices, although they are inherently of interest and may affect patient-counseling practices. This study evaluated the
health practices and the vaccination status of first year residents working at the academic hospital Hotel-Dieu de
France. The medical files of all medicine and surgery residents in their first year of specialization between the years
2005 and 2008 were reviewed. These residents were required to go through a preventive medical visit at the University
Center of Family and Community Health. One hundred and nine residents [109] were included in the study; 68
[62.39%] were male and 41 [37.61%] were female with a mean age of 26 years. Only 6 residents [5.50%] practiced
physical activity according to international guidelines [more than three times a week for more than 30 minutes each
time]. Most residents [n=76; 69.73%] used to skip one or two meals especially breakfast and as a consequence 30
male [44.11%] and 4 female [9.75%] students were overweight, with a statistical difference between the two sexes
[Fisher test, p-value=0.001]. Twenty-eight residents [25.69%] were smokers with a male predominance. Fourteen
residents of both genders [12.84%] drank alcohol regularly [>3 times a week] and 71 [65.14%] had a drink occasionally
[once a month or less]. Only 25 residents [23%] of the cohort had a complete and up-to-date immunization status. The
immunization gap was basically against measles, mumps, rubella [MMR] and diphtheria, tetanus, poliomyelitis [dT
Polio]. Ninety-nine residents [90.83%] had full immunization against hepatitis B with an adequate response in 78
residents [71.56%]. This study showed that our residents did not always have a healthy lifestyle especially when it
comes to physical activity and eating habits. They also lacked an adequate vaccination. Interventions should take
place in order to promote healthy life style and to improve their vaccination status.
Substance-Related Disorders
epidemiology
[A rapid situation assessment [RSA] study of alcohol and drug use in Lebanon].
Karam, Elie G.; Ghandour, Lilian A.; Maalouf, Wadih E.; Yamout, Karim; Salamoun, Mariana M.
E-mail:[email protected]
Balamand University - School of Medicine - Department of Psychiatry and Clinical Psychology
LMJ - Lebanese Medical Journal 2010; 58 (2): 76-85 (30 ref.)
Keywords: Alcohol-Related Disorders-epidemiology; Smoking; Cannabis; Heroin; Schools; Universities; CrossSectional Studies
Abstract: Research on substance use and misuse in Lebanon is scarce and, when available, focuses on a specific
substance or a limited segment of the population. The objective of this Rapid Situation Assessment [RAS] study was to
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survey the use of multiple substances in diverse segments of the Lebanese population. A multi-method and multisample survey was conducted to collect quantitative and qualitative data from the academic sector [high school and
university students], substance users in treatment or under arrest [prison, detention], and non-institutionalized "street"
users. Age of first use of substances started as early as 9 years in the youth sample. Moreover, 12% of the high school
students reported smoking one or more packs of cigarettes per day and 9% of the university students met criteria for
DSM-IV alcohol abuse. Cannabis represented the most commonly used illicit drug in both high school and university
students, and tranquilizers were the most frequently misused medicinal substance. Heroin was responsible for 50% of
the treatment admissions, followed by cocaine [20%], and alcohol [20%]; heroin was also the most common substance
of arrest. Recidivism was almost the rule for heroin users across all treatment settings. Unperceived need for treatment
was the most common reason for not seeking treatment in non-institutionalized drug users [47.6%]. Injecting drug use
was a common behavior noted within substance using populations, in treatment and non-institutionalized [about 50%
of them], with a high rate of needle sharing practices. About half of all patients in treatment had a history of police
arrests, and about one-third of those in prison ever received prior treatment for substance use. The study points
towards a growing trend for substance use problems in early adolescence that warrants close monitoring. Further
investigation of these patterns is needed since the Lebanese population might have specific pathways of abuse. There
is a need to bring together various health, legislative, and academic stakeholders for a continuous appraisal of data
from substance abuse studies as evidenced by the recent, although slow, progress in the fields of legislation and
treatment that follow such concerted efforts.
Surgery, Computer-Assisted
Image guidance surgery: is it useful to the orbital surgeon?
Durairaj, Vikram D.
University of Colorado - School of Medicine - Department of Ophthalmology and Otolaryngology
Saudi Journal of Ophthalmology 2010; 24 (3): 67-68 (2 ref.)
Keywords: Orbit-surgery
Survival Analysis
Parametric modelling of survival following HIV and AIDS in the era of highly active antiretroviral
therapy: data from Australia.
Nakhaee, F.; Law, M.
E-mail:[email protected]
Kerman University of Medical Sciences - Faculty of Health - Department of Biostatistics and Epidemiology
EMHJ - Eastern Mediterranean Health Journal 2011; 17 (3): 231-237 (24 ref.)
Keywords: Models, Statistical; HIV Infections; Acquired Immunodeficiency Syndrome; Anti-Retroviral Agents
Abstract: Parametric survival models have not previously been applied to survival following a diagnosis of HIV/ AIDS
in Australia. Four different parametric models-exponential, Weibull, log-normal and log-logistic-were applied to data
both on HIV-positive cases and on cases diagnosed with AIDS collected through the national HIV/AIDS surveillance
system. Using likelihood based goodness-of-fit criteria the Weibull model was found to be the best-fitted model for
predicting survival following a diagnosis of HIV infection without and with a diagnosis of AIDS. Several covariates-age,
sex, combined HIV exposure category, CD4 cell counts, antiretroviral treatment and AIDS-defining illnesses-were
included in the parametric model to predict factors associated with future mortality. Predicted deaths were in
agreement with the observed deaths following HIV infection and AIDS. The Weibull model will be applied for future
projections of deaths from HIV/AIDS.
Technetium Tc 99m Sestamibi
diagnostic use
Diagnostic accuracy of [99m]TC-MIBI for breast carcinoma in correlation with mammography
and sonography.
Tunio, Mutahir Ali
E-mail:[email protected]
Radiation Oncology Sindh Institute of Urology and Transplantation [SIUT]
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 289 (4 ref.)
Keywords: Carcinoma, Ductal, Breast-diagnosis; Carcinoma, Ductal, Breast-Radionuclide Imaging; Carcinoma,
Ductal, Breast-ultrasonography; Mammography; Ultrasonography, Mammary; Biopsy
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Theileria
Parasitology
Detection of Theileria infection in dromedary camels.
El Maghrbi, A.A.; Hosni, M.M.
Alfatah University - Faculty of Vet. Medicine - Department of Microbiology and Parasitology
Veterinary Medical Journal 2009; 57 (1): 53-58 (20 ref.)
Keywords: Prevalence; Camels; Ticks; Erythrocytes; TEB p pretein, hyalomma dromedarii
Abstract: Camels are important source of meat and wool. These products depend mainly on the general health
conditions which are affected by infection with several diseases such as blood parasites. The examination was done
on 215 camels by Giemsa stained blood films prepared from the blood collected from imported camels slaughtered at
three slaughter house in Tripoli-Libya [February July 2008]. Out of 215 examined camels, 14 [6.5%] were infected with
Theileria spp. The morphology of the detected Theileria in the erythrocytes was oval forms. The main size measured
1.3 x 0.4 micro m. The schizonts inside the lymphocyte were irregular in shape and showed varying number of red
granules. Hyalomma dromedarii were identified from the camels infected with Theileria.
Thyroid Function Tests
The diagnostic yield of thyroid function tests and their cost-effectiveness in the student clinic at
Sultan Qaboos University: retrospective chart review.
El Shafie, Kawther; Al Shaqsi, Asila; Al Mahrouqi, Badriya; Al Lawati, Hadia; Ganguly, Shyam S.; Al Adawi, Samir; Al
Shafaee, Mohammed
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Family Medicine and Public
Health
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 215-220 (25 ref.)
Keywords: Cost-Benefit Analysis; Retrospective Studies; Students; Universities
Abstract: To assess the significance of requesting thyroid function tests [TFT] and their cost effectiveness for
specific and non-specific symptoms of thyroid disease in a specific population in Oman. A retrospective chart review
study was conducted in the student clinic at Sultan Qaboos University in Oman in the year 2007-2008. It included all
patients [N=319] of both sexes for whom TFTs were requested. The patients' main complaints and the final diagnoses
were collected from their medical records. The most common presentations for which TFTs were requested were
irregular periods [n=82]; fatiguability [n=49], palpitations [n=39]; weight changes [n=22]; hair changes [n=20]; sensation
of heat and cold [n=18]; diarrhoea and constipation [n=13], and neck swelling [n=13].The most common diagnoses
reached in relation to these complaints were polycystic ovarian syndrome [n=51]; iron deficiency anaemia [n=42];
anxiety and depression [n=11] ; thyroid disease [n=18], and no specific diagnosis [n=193]. The percentage of thyroid
diseases among females [7.1%] compared to males [1.2%] was statistically significant [P <0.05]. Thyroid disease
accounted for 61.5% of those patient with neck swelling, 7.7% of those with palpitations, 4.1% of those with fatigue, 3%
of those with other complaints, and 1.2% of those with irregular periods. The cost of the tests was around 20,000 US
dollars. TFT is necessary for those presenting with neck swelling, but restraint should be used in administering the test
for those complaining of palpitations or fatigue. Additionally, irregular periods have little link with TFT abnormality.
Thyroid Neoplasms
pathology
Multiple bone metastases in a patient with differentiated thyroid cancer [DTC]: complete
resolution following thyroidectomy and four ablation doses of 1-131.
Elshafie, Omayma T.; Hussein, Samir; Al Hamdani, Aisha; Bererhi, Haddia; Woodhouse, Nicholas J.Y.
E-mail:[email protected]
Sultan Qaboos University Hospital - Departments of Medicine
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 101-105 (13 ref.)
Keywords: Thyroid Neoplasms-complications; Neoplasm Metastasis; Thyroid Neoplasms-radiotherapy; Thyroid
Neoplasms-surgery; Bone Neoplasms; Iodine Radioisotopes-therapeutic use
Abstract: Multiple bone metastases from a differentiated thyroid cancer are usually incurable. We report the case of
a young Omani woman who presented with 8 discrete skeletal lesions three years after a total thyroidectomy.
Following four ablation doses of I-131 she has remained in clinical and biochemical remission for over five years. An
extraordinary aspect of this case was the persistent refusal of her husband to use contraception either for himself or his
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wife. This resulted in her treatment being delayed for more than 6 years during which time the patient delivered and
breastfed four additional healthy babies.
Thyrotoxicosis
radiotherapy
Re: radiation exposure levels in family members of Omani patients with thyrotoxicosis treated
with radioiodine [I-131] as outpatients.
Ravichandran, Ramamoorthy; Al Saadi, Amal
E-mail:[email protected]
National Oncology Center
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (1): 138-141 (6 ref.)
Keywords: Radiation Injuries; Maximum Allowable Concentration; Family; Iodine Radioisotopes-adverse effects
Timolol
therapeutic use
Evaluation of the role of timolol 0.1% gel in myopic regression after laser in situ keratomileusis.
El Awady, Hatem E.; Ghanem, Asaad A.; Gad, Mohamed A.
Mansoura University - Faculty of Medicine
Saudi Journal of Ophthalmology 2010; 24 (3): 81-86 (12 ref.)
Keywords: Timolol-administration and dosage; Myopia; Keratomileusis, Laser In Situ; Prospective Studies;
Treatment Outcome
Abstract: To evaluate the efficacy of the concomitant administration of antiglaucoma medications namely timolol
0.1% gel in cases with myopic regression after myopic laser in situ keratomileusis [LASIK]. Prospective observational
clinical trial. Ninty five eyes of 75 patients were included in this study prospectively. The mean myopic regression was1.29 +/- 0.83 diopters [range-0.5 to-4.62] after myopic LASIK. The eyes were divided into two groups: 50 eyes
administrated timolol 0.1% gel once daily for 12 months [treated group], and 45 eyes were age matched [control
group]. We assessed the amounts of myopic regression in terms of changes in the refraction [spherical equivalent and
astigmatism], intraocular pressure [IOP], pachymetry and the refractive power of the cornea measurements for all
participants. The refractive error and visual acuity were similar between the two groups at baseline. The treated group
had an improvement in spherical equivalent significantly from-1.29 +/- 0.83 to-0.94 +/- 1.07 diopters [P=0.012].
Astigmatism was changed from-0.94 +/- 0.53 to-0.86 +/- 0.60 diopters but this change was not statistically significant
[P=0.20]. The IOP was decreased significantly from 12.6 +/- 1.9 to 9.0 +/- 1.1 mm Hg [P<0.001]. Central corneal
thickness was changed from 425.6 +/- 19.86 to 429 +/- 18.1 micro m but not statistically significant [P=0.56]. The
central corneal power decreased significantly from 37.2 +/- 1.8 to 36.4 +/- 1.3 diopters [P<0.05]. Timolol 0.1% gel was
effective for reduction and improvement of myopic regression especially the spherical errors after myopic LASIK.
Tooth
growth and development
Dental maturity amongst various vertical and sagittal facial patterns.
Sukhia, Rashna H.; Fida, Mubassar
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 225-228 (20 ref.)
Keywords: Face-anatomy and histology; Cross-Sectional Studies; Retrospective Studies
Abstract: To compare the mean dental maturity amongst three vertical facial patterns [short, average and long
anterior facial heights] and also amongst two sagittal facial patterns [skeletal class I and II] in orthodontic patients.
Cross-sectional analytical study. The Aga Khan University Hospital, Karachi, from August to October 2008. Data was
retrospectively retrieved from pretreatment orthodontic records of patients who visited the orthodontic clinic. The
sample was divided into three vertical groups, namely short, average and long anterior facial types, and two sagittal
groups, namely skeletal class I and II. Dental development was assessed using the Demirjian's system. One way
ANOVA and independent sample t-test were used to find any difference in dental maturity amongst vertical and sagittal
facial patterns, respectively. There was no statistically significant difference in dental maturity amongst the three
vertical facial patterns [p=0.111] and also amongst the two sagittal groups [p=0.975]. Statistically significant gender
dimorphism [p < 0.001] was seen amongst boys and girls for dental maturity with girls being more advanced than boys
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Subject Index
in their dental development. Dental maturation in the three vertical and the two sagittal groups showed no statistically
significant difference in our studied population sample and thus need no variations in treatment initiation timings.
However, girls should be treated earlier as they are dentally more advanced than boys.
Tracheostomy
An evaluation of the quality of life in patients with tracheostomy.
Gul, Nur Dilek; Karadag, Ayise
Hacettepe University Adult Hospital - Department of Ear, Nose and Throat Clinic
Pakistan Journal of Medical Sciences 2010; 26 (2): 444-449 (21 ref.)
Keywords: Quality of Life; Nursing Care; Questionnaires
Abstract: To evaluate the quality of life in patients with tracheostomy. All the patients, who have had tracheostomy
operations between 1998-2009 at a University Hospital, Turkey, constitute the population of the study [70 patients].
The data have been collected between June-July 2009 by using the Short Form 36 Quality of Life Scale [QoL]. It has
been determined that the QoL scores of patients, whose life span with tracheostomy is three months to one year, who
have received chemotherapy or radiotherapy, have difficulties in breathing and eating are lower in the various subdimensions of the QoL scale. Together with this, it has been determined that the scores of patients who can perform
their tracheostomy care independently, have no complications, use esophageal speech, whose sense of smell has not
been impaired, and state that their physical appearance has not been affected are higher in the various subdimensions the Quality of Life [QoL] scale. Tracheostomy has a profoundly negative impact on quality of life.
Trial of Labor
Magnetic resonance pelvimetry for trial of labour after a previous caesarean section.
Gowri, Vaidyanathan; Jain, Rajeev; Rizvi, Syed
E-mail:[email protected]
Sultan Qaboos University - College of Medicine and Health Sciences - Department of Obstetrics and Gynaecology
SQUMJ - Sultan Qaboos University Medical Journal 2010; 10 (2): 210-214 (14 ref.)
Keywords: Pelvimetry; Cesarean Section; Pregnancy; Retrospective Studies; Magnetic Resonance Spectroscopy;
Delivery, Obstetric
Abstract: To stratify the magnetic resonance [MR] pelvimetric diameters according to mode of delivery and establish
possible reference values for pelvic diameters and outlet index for trial of labor after a previous caesarean section. This
is a retrospective study of 125 patients at Sultan Qaboos University Hospital who underwent MR pelvimetry prior to a
trial of vaginal delivery after a previous caesarean section between May 2001 and October 2003. Sagittal inlet,
Transverse inlet, interspinous diameter, sagittal outlet and transverse outlet diameters were measured in all patients.
The mean diameters were stratified according to delivery modality [vaginal delivery or caesarean section]. The outlet
index [sum of interspinous, sagittal outlet and intertuberous diameters], biparietal diameter of the foetus and head
circumference were compared in women who delivered by caesarean section or vaginally. All the diameters except
sagittal inlet, were significantly larger [P < 0.05] in women who delivered normally as compared with those who had a
caesarean section for any indication. The mean outlet index in the spontaneous delivery group with vertex presentation
31.89 +/- 2.05, was significantly larger than that of the elective and emergency caesarean section, which were 29.69
+/- 1.85 and 30.62 +/- 1.80 respectively. The mean head circumference was also found to be significantly larger in the
caesarean section deliveries. An outlet index of 31.89 +/- 2.05 and the pelvic diameters, transverse inlet 12.56 +/0.80cm, sagittal outlet 10.54 +/- 1.00 cm, interspinous diameter10.46 +/- 0.89cm, and intertuberous diameter
[transverse outlet] 10.89 +/- 1.02cm are useful cut-off points for vaginal delivery in our population.
Trigonella
Antineoplastic effect of Fenugreek [Trigonella Foenum Graecum] seed extract against acute
myeloblastic leukemia cell line [KG-1].
Alizadeh, Shaban; Jahanmehr, Seyed Abdol Hamid; Ardjmand, Ali Reza; Rezaian, Mostafa; Dargahi, Hosejn; Einolahi,
Nahid; Sadrossadat, Monjreh
E-mail:[email protected]
Tehran University of Medical Sciences - Faculty of Allied Medical Sciences - Hematology and Blood Banking
department
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 139-146 (50 ref.)
Keywords: Plant Extracts-therapeutic use; Leukemia, Myelocytic, Acute-drug therapy; Treatment Outcome;
Apoptosis; Antifibrinolytic Agents
Abstract: Treatment of cancer patients using conventional chemotherapy causes serious side effects and, at best,
merely extends the patient's lifespan by a few years. The potential of alternative therapies may therefore be of great
benefit in cancer control. The effect of Trigonella Foenum Graecum seed extract has been previously reported on
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some neoplastic cells. Here, its effect is evaluated on human acute myeloblastic leukemia cell lines. The cell line KG-1
was treated with various concentrations of Fenugreek seeds extract with various durations. Cellular enumeration,
viability test, staining and light microscopy, and apoptosis induction were evaluated. Results showed significant
cytotoxic effect of Fenugreek seeds extract against this cell line which resulted in growth inhibition, cell death and
morphological changes. Apoptosis induction was not considerable. Fenugreek seeds extract did not change the count
and morphology of normal lymphocytes. Applying herbal medicines could be an effective and safe treatment for
leukemia. To our knowledge, this is the first study that suggests significant chemotherapeutic effects of Fenugreek
seeds against these cell lines.
Tuberculosis, Meningeal
diagnosis
Modified kenneth jones criteria for diagnosing tuberculous meningitis in children.
Anwar, Muhammad; Ahmad, Ameer; Ahmad, Fiaz; Mazhar, Attaullah
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 258-261 (20 ref.)
Keywords: Cross-Sectional Studies; Tuberculosis, Meningeal-cerebrospinal fluid; Early Diagnosis
Abstract: To evaluate accuracy of modified Kenneth Jones scoring criteria [MKJSC] as a screening tool to diagnose
tuberculous meningitis in children. Cross-sectional study. Paediatric Medicine, Unit-1, Bahawal Victoria Hospital,
Bahawalpur, from May 2006 to March 2007. A total of 100 children admitted through emergency in Paediatric
Medicine, Unit-l, were included who were having fever and features suggestive of central nervous system [CNS]
infection. Lumbar puncture was done in all patients after written consent. Findings of lumbar puncture were taken as
gold standard for the diagnosis of IBM. MKJSC was applied on each patient and accuracy determined against the gold
standard. Out of 100 children, 47 were diagnosed as IBM on the basis of CSF results. All children had scored 0-7 or
above according to MKJSC. A score 1-2, 3-4, 5-6 and 7 or more was obtained in 23, 25, 30 and 22 children
respectively. Children who had scored 5 or more received ATT. Accuracy of MKJSC was calculated to be 91%.
MKJSC is a simple and accurate tool to improve tuberculous meningitis case detection rate in children.
Tuberculosis, Pulmonary
drug therapy
Drug resistance pattern in multidrug resistance pulmonary tuberculosis patients.
Rao, Nisar Ahmed; Irfan, Muhammad; Soomro, Mir Muhammad; Mehfooz, Zeeshan
E-mail:[email protected]
Ojha Institute of Chest Diseases - Department of Pulmonology
JCPSP - Journal of the College of Physicians and Surgeons Pakistan 2010; 20 (4): 262-265 (25 ref.)
Keywords: Tuberculosis, Multidrug-Resistant; Retrospective Studies; Microbial Sensitivity Tests
Abstract: To evaluate the frequency of drug resistance profiles of multidrug resistant tuberculosis [MDR-TB] isolates
of pulmonary tuberculosis patients, against both the first and the second line drugs. An observational study. The
multidrug resistant tuberculosis [MDR-TB] ward of Ojha Institute of Chest Diseases, Karachi, from 1996 to 2006.
Culture proven MDR-TB cases [resistant to both isoniazid and Rifampicin] were retrospectively reviewed. Susceptibility
testing was performed at the clinical laboratory of the Aga Khan University. Sensitivity against both first and second
line anti-tuberculosis drugs was done. Susceptibility testing was performed using Agar proportion method on enriched
middle brook 7H10 medium [BBL] for Rifampicin, Isoniazid, Streptomycin, Ethambutol, Ethionamide, Capreomycin and
Ciprofloxacin. Pyrazinamide sensitivity was carried out using the BACTEC 7H12 medium. During the study period MTB
H37Rv was used as control. Out of total 577 patients, all were resistant to both Rifampicin and Isoniazid [INH]. 56.5%
isolates were resistant to all five first line drugs. Resistances against other first line drugs was 76.60% for
Pyrazinamide, 73% for Ethambutol and 68.11% for Streptomycin. Five hundred and ten [88%] cases were MDR plus
resistant to one more first line drug. Forty [07%] isolates were MDR plus Quinolone-resistant. They were sensitive to
Capreomycin but sensitivity against Amikacin and Kanamycin were not tested. There were high resistance rates in
MDR-TB to remaining first line and second line drugs. Continuous monitoring of drug resistance pattern especially of
MDR isolates and treatment in specialized centers is a crucial need for future TB control in Pakistan.
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Tumor Lysis Syndrome
etiology
Spontaneous tumor lysis syndrome: a case report and review of literature.
Hashem, Ashraf Ahmed Hussein; Dowod, Tarek Abdel Hameed Mostafa; Abdelmajeed, Mohsen Mahmooud
E-mail:[email protected]
Ministry of Health - Adan Hospital - Medical Department
Pakistan Journal of Medical Sciences 2010; 26 (2): 458-463 (19 ref.)
Keywords: Tumor Lysis Syndrome-diagnosis; Tumor Lysis Syndrome-drug therapy; Kidney Failure-etiology;
Hyperkalemia; Uric Acid-blood; Prostatic Neoplasms-complications
Abstract: We report a case of spontaneous tumour lysis syndrome [STLS] in a patient with disseminated hormonal
refractory cancer prostate. Tumour lysis syndrome [TLS] complicating Non-Hematological malignancy is infrequent and
STLS is a very rare occurrence in solid tumor. Clinicians should keep in mind the possibility of STLS in patients with
solid tumor and should have the experience to interpret the clinical and laboratory tests to identify it and rapidly initiate
its management.
Urinary Bladder Neoplasms
genetics
CTLA-4 Exon one +49 A/G gene variants in patients with superficial and invasive bladder cancer:
a study in southern Iran.
Aminsharifi, Alireza; Ghaderi, Abbas; Naeimi, Sirous; Khezri, Abdolaziz; Agahi, Neda; Aminiarr, Amir; Zamiri, Nima
Shiraz University of Medical Sciences - Department of Urology
MEJC - Middle East Journal of Cancer 2010; 1 (1): 15-20 (19 ref.)
Keywords: Urinary Bladder Neoplasms-immunology; Antigens, CD; Polymorphism, Genetic; Genotype
Abstract: Cytotoxic T-cell lymphocyte antigen 4 [CTLA-4] is a member of the superfamily of immunoglobulins that
are mainly expressed by activated T cells. It is established that blockade of CTLA-4 receptors leads to the
enhancement of an immune response. Different polymorphisms of the CTLA-4 gene have been described which cause
increased susceptibility to various malignancies such as lymphoma or multiple myeloma. Considering that bladder
cancer is one of the most prevalent cancers worldwide, we have evaluated the role of CTLA-4 gene polymorphism at
position +49 A/G in the formation or progression of bladder cancer in southern Iran. A total of 226 individuals between
February 2005 and June 2006 were included and placed into two subgroups: patients diagnosed with bladder cancer
and a control group. Demographic data and risk factors were collected from both groups. The DNA of all subjects was
extracted from their blood samples. Different genotypes of the CTLA-4 gene were determined using the restriction
fragment length polymorphism [RFLP] technique and data were compared in both groups by using Pearson's chisquare test. The prevalence of AA, AG and GG genotypes at position 49, according to the PCR-RFLP method, were
57.5%, 37.2% and 5.3% in the control group, respectively. In the patient group, the prevalence of these genotypes
was: AA in 57.5%, AG in 32.7% and GG in 9.8%. Statistical analysis of data showed no significant difference in both
groups [P value=0.40]. Also there was no correlation between different genotypes of the CTLA-4 gene and
invasiveness of the disease in our cases. Although polymorphism of the CTLA-4 gene at position 49 of exon-1
increases susceptibility to several malignancies, our study showed no relationship between polymorphism at this
position and genetic susceptibility to the development of bladder cancer, nor was there any association with disease
progression.
Urinary Diversion
methods
Outcomes of transurethral and suprapubic urinary diversion following hypospadias repair in
children.
Osifo, Osarumwense David; Azeez, Abiodun Luqman
E-mail:[email protected]
University of Benin - Teaching Hospital - Paediatric Surgery Unit
Pakistan Journal of Medical Sciences 2010; 26 (2): 329-334 (18 ref.)
Keywords: Hypospadias-surgery; Treatment Outcome; Prospective Studies; Cystostomy
Abstract: To determine the outcomes and efficacy of transurethral urinary diversion/stenting with size six feeding
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Subject Index
tube and that of suprapubic cystostomy after hypospadias repair in children. An 8-year prospective experience at the
University of Benin Teaching Hospital on the outcomes of suprapubic urinary diversion [2000-2002] and transurethral
diversion/stenting [2003-2007] after hypospadias repair in children. During the study period, a total of 196 children had
urinary diversion following hypospadias repair, 69 [35.2%] suprapubic and 127 [64.8%] transurethral. They were aged
between 6 months and 12 years. Children who had transurethral diversion were relatively younger [mean age 2.3 +/2.1 years] compared to suprapubic [3 +/- 3.8 years]. Although anchorage to the glans penis and bed restriction in 115
[90.6%] children were required, urinary diversion was more effective, postoperative complications were rare, no trigone
irritation, and excellent cosmetic results [121 [95.3%]] were recorded following transurethral diversion with a size six
feeding tube. Conversely, the creation of suprapubic cystostomy increased operation and hospitalization duration with
higher incidences of trigone irritation, 28 [4.6%], fistula formation, 18 [26.1%], catheter blockage, 10 [14.5%], soiling of
operation site with urine and fewer number of children [48 [69.6%]] with excellent cosmetic results. Transurethral
urinary diversion/stenting with a size six feeding tube was very effective and gave better results than suprapubic
cystostomy. The feeding tube is cheap, readily available and may provide a better means of post hypospadias repair
urinary diversion in children where an ideal transurethral paediatric catheter is not available.
Urological Manifestations
Prevalence of lower urinary tract symptoms among men in a rural district of western Turkey.
Unsal, Alaettin; Ayranci, Unal; Tozun, Mustafa
Eskisehir Osmangazi University - Medical Faculty - Public Health Department
Pakistan Journal of Medical Sciences 2010; 26 (2): 294-299 (28 ref.)
Keywords: Prevalence; Rural Population; Risk Factors; Cross-Sectional Studies
Abstract: The aim was to determine the prevalence of lower urinary tract symptoms [LUTS] in men aged 40 years or
older, as well as to compare characteristics of patients with and without LUTS. The paper is a cross-sectional survey
conducted on men with LUTS in a district of western Turkey between November 1st and December 31st. The
questionnaire was filled in by a face to face method, and consisted of the men's socio-demographic characteristics,
LUTS related characteristics, and the questions pertaining to international prostate symptom score [IPSS]. The
prevalence of LUTS was 51.5%. The comparative analyses between patients who had and those who did not have
LUTS showed that patients in settlement area Kaymaz, those aged 70 and over, those with primary school education
and below, those who were married, those who had recurrent UTI, those who were using medicines continuously,
those with a history of previous surgery, those with family history of LUTS had a higher prevalence of LUTS. In
conclusion the number of the respondents having LUTS was common among men in this region of Turkey.
Uterine Prolapse
surgery
Evaluation of a modified surgical technique for correction of vaginal and uterine prolapse in
bovine.
Hussien, M.M.; Abdel Fattah, M.; Khalil, A.A.Y.; Sedeek, A.M.
Beni-Suef University - Faculty of Vet. Medicine - Department of Theriogenology
Veterinary Medical Journal 2009; 57 (1): 115-131 (47 ref.)
Keywords: Pelvic Organ Prolopse-surgery; Cattle Diseases
Abstract: This study was carried out on 81 cows [48 vaginal and 33 uterine prolapses] and 83 buffalo-cows [53
vaginal and 30 uterine prolapses] belonging to 8 commercial dairy farms located in Beni-Suef, El-Menia and ElFayoum provinces in the period from January 2006 to December 2008. A modified surgical technique and epidural
analgesic regimen were applied on the investigated animals and compared with the field traditionally used technique. A
total of 81 cases of prolapses from 3330 calveings [243%] were recorded, 48 cases [1.44%] of them were vaginal
prolapse and 33 cases [0.99%] were uterine prolapse. Concerning buffalo cows, out of 1680 calvings, a total of 83
cases [4.94%] had prolapses, including 53 cases [3.15%] vaginal prolapse and 30 cases [1.78%] uterine prolapse. The
incidence of reproductive tract prolapse was higher in multiparous aged cows [93.75% and 87.88% vaginal and uterine
prolapse, respectively] than in primiparous cows [6.25% and 12.12% vaginal and uterine prolapses, respectively] and
also higher in cows with poor body condition scores [1.66% vaginal and 1.10% uterine] than in well fed animals with
good body condition score [1.05% vaginal and 0.91% uterine]. Buffalo cows showed the same trend. About 4 5.83% of
cows with vaginal and 33.33% of cows with uterine prolapse were previously suffered from vaginal prolapse, while only
16.66% of cows with vaginal and 12.12% of those with uterine prolapse were previously suffered from uterine prolapse.
This indicated that uterine prolapse is not a heritable condition, and it is not likely to reoccur, and there is no need to
cull the cow as long as she breeds back, controversial to vaginal prolapses that reoccur and are heritable and needs
culling of the cow and her heifer offspring. The investigated fertility parameters in unaffected animals were better than
females affected with prolapses, although better non significant differences were detected with modified method than
traditional ones. The incidence of postoperative complications in groups of animals treated with the modified technique
were significantly [p<0.01] lower than in animals treated with traditional technique. Concerning the survival rate of the
affected animals, higher percentages were recorded after using the modified technique. In general, the prognosis was
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favorable for uncomplicated cases. In conclusion, early hygienic interference and prompt treatment using the modified
technique may be imperative to improve the prognosis by reducing the postoperative complications and increasing the
future fertility of affected animals.
Venous Thrombosis
genetics
Methyltetrahydrofolate reductase C677T mutation and 4G/5G plasminogen activator inhibitor-I
polymorphism in a child with deep vein thrombosis.
Eshghi, Peyman; Pour, Kourosh Goudarzi; Aghakhani, Roxana
E-mail:[email protected]
Shaheed Beheshti University of Medical Sciences - Departmen of Pediatric Hematoiogy/Oncology
IJBC - Iranian Journal of blood and Cancer 2009; 1 (4): 167-170 (16 ref.)
Keywords: Venous Thrombosis-enzymology; Plasminogen Activator Inhibitor 1-genetics; Polymorphism, Genetic;
Mutation-genetics
Vesicovaginal Fistula
etiology
Intra vaginal wooden foreign body causing multiple internal fistulae and bladder stone in a 12
years girl.
Jan, Iftikhar Ahmad; Arif, Khurrum; ul Haq, Anwar; Gondal, Mudassar; Orakzai, Hazratullah
E-mail:[email protected]
National Institute of Rehabilitation Medicine - Department of Pediatric Surgery
Pakistan Journal of Medical Sciences 2010; 26 (2): 470-473 (10 ref.)
Keywords: Foreign Bodies-complications; Vagina-pathology; Urinary Bladder Calculi
Abstract: Vaginal foreign bodies in girls may be accidental, self-inflicted or secondary to child abuse. These may
causes a number of complications like Infections, abscess formation, intestinal perforation, vaginal discharge and
internal fistulae. We are presenting a case of a 13 years old girl who presented with a supra-pubic mass and dysuria.
X-ray showed a radio-opaque shadow in pelvis. The child was admitted in medical ward with the diagnosis of bladder
stone and UTI. She was pouring frank pus from the vagina. On rectal digital examination a hard foreign body was felt in
the rectum. Investigations revealed that she had a large pelvic collection, a sharp wooden Foreign Body [FB] extending
from the rectum through the vagina in to the urinary bladder forming a bladder stone. Patient also developed rectovaginal and vesico-vaginal fistulae. Foreign body was removed along with the bladder stone, pelvic abscess drained
and colostomy was performed. Later repair of vesico-vaginal fistula were performed, recto-vaginal fistula closed
spontaneously and colostomy closed. Patient became fully continent for urine and feces after completion of surgical
procedures. A careful history from the child revealed that she had inserted the foreign body herself as a self-exploring
practice.
Profile of women who experienced vesicovaginal fistula due to obstetric trauma.
Rafi, Junaid
E-mail:[email protected]
Department of Obstetrics and Gynaecology
Pakistan Journal of Medical Sciences 2010; 26 (2): 499 (1 ref.)
Keywords: Wounds and Injuries; Delivery, Obstetric-adverse effects; Correspondence as Topic
Wounds and Injuries
Injury patterns from road traffic accidents.
Khan, Zaka U.; Al Asiri, Khaled M.; Iqbal, Javaid
E-mail:[email protected]
Armed Forces Hospital - Department of Trauma and Orthopaedics
Pakistan Journal of Medical Sciences 2010; 26 (2): 394-397 (9 ref.)
Keywords: Accidents, Traffic; Prospective Studies; Causality
Abstract: To report the pattern of injuries from high speed road traffic accidents [RTA] in the Southern Region of
Saudi Arabia. In this prospective criteria based one year study; data was collected upon arrival of patients to the
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Subject Index
accident and emergency department. The patients were grouped into two, with fractures [Group-1] and without [Group2]. A total of 1513 patients were included, 628 in Group-1 and 885 in Group-2. There were 1356 male and 157 female
patients in total. Majority were in the younger age group, drivers and front seat passengers. Fewer were using restrains
and more reported driving with high speeds in group-1 compared to group-2. Most accidents occurred during 12:00 hrs
to 24:00 hrs in both groups. Although most of the causative factors of Road traffic accidents in this region of Saudi
Arabia are similar to the rest of the world; some remain unique to the region.
90
Appendix I
Author Index
IMEMR Current Contents
Author Index
Abbasi, H.
Afsar, Salahuddin
DENTAL DEVICES, HOME CARE
INJECTIONS
Abdel Fattah, M.
Afzal, Waseem
UTERINE PROLAPSE (surgery)
HUMERAL FRACTURES (surgery)
Abdel Gawad, Soad M.
Agahi, Neda
CHOLESTASIS (etiology)
URINARY BLADDER NEOPLASMS (genetics)
Abdelmajeed, Mohsen Mahmooud
Agboke, A.
TUMOR LYSIS SYNDROME (etiology)
PLANT EXTRACTS (pharmacology)
Abdollahifard, Seddigheh
Aghakhani, Roxana
POLYCYSTIC OVARY SYNDROME (drug
therapy)
VENOUS THROMBOSIS (genetics)
Aghamohammadi, Azar
Abdou, Ahmed M. Saleh
PREGNANCY OUTCOME
BEHCET SYNDROME
Aghamohammadzadeh, Nasser
Abdul Halim, Ibrahim M.
AMINO ACIDS (urine)
POLYCYSTIC OVARY SYNDROME (drug
therapy)
Abdul Jalil, Huda K.
Ahamed, Nissara
AMINO ACIDS (urine)
PLANT GUMS (administration and dosage)
Abdul Rahim, H.F.
Ahmad, Aksam J.
ANEMIA (epidemiology)
MIOSIS (prevention and control)
Abdullah, Rana M.
Ahmad, Ameer
BETA-LACTAMS
TUBERCULOSIS, MENINGEAL (diagnosis)
Abdulrazaq, May R.
Ahmad, Fiaz
NEOPLASMS (epidemiology)
TUBERCULOSIS, MENINGEAL (diagnosis)
Abed, Ali
Ahmad, Merhij
HEARING LOSS, SENSORINEURAL
(epidemiology)
LARYNGOSCOPY
Ahmadloo, Niloofar
Abed, Y.
MENINGIOMA (pathology)
DIET
Ahmed, Abbas Abdulkader
Abi Rizk, G.
GROWTH
STUDENTS, MEDICAL
Ahmed, Aneela
Abid, Hamida
COMMUNICATION
BEVERAGES (microbiology)
Ahmed, Bilal
Abolghasemi, Hassan
ANODONTIA
INTERFERON ALFA-2A (therapeutic use)
Ahmed, Hafeez
Abrjshamkar, Mahboobeh
HYDROXYUREA (therapeutic use)
ANGIOPLASTY, TRANSLUMINAL,
PERCUTANEOUS CORONARY
Abro, Ali Hassan
Ahmed, Mohd. Gulzar
HEPATITIS C ANTIBODIES (immunology)
BEHCET SYNDROME
PLANT GUMS (administration and dosage)
Ahmed, N.
Absar, Syeda Fatima
MEDICAL RECORDS
INFECTION CONTROL
Ahmed, Shadab
Abu Eisheh, Asem
PLANTS, MEDICINAL (toxicity)
BODY COMPOSITION
Ahmed, Syed Waseemuddin
Abudayya, A.
ALKALOIDS (isolation and purification)
DIET
Ahmed, Waqas
Abuelhamd, Ashraf T.
PERICARDITIS, CONSTRICTIVE (microbiology)
LEUKOEYTES (physiology)
Ahmed, Zubair
Adnan, Sara
ESOPHAGEAL NEOPLASMS (pathology)
STRESS, PSYCHOLOGICAL
Akhtar, Naveed
Afifi, Mohamed Tamer
PERICARDITIS, CONSTRICTIVE (microbiology)
INTESTINAL DISEASES (diagnosis)
Akinloye, O.
Afroz, Syeda
CONTRACEPTION
PLANTS, MEDICINAL (toxicity)
93 IMEMR Current Contents
Author Index
Akman, Mehmet
Al Khabori, Mazin
FOOD MICROBIOLOGY
HEARING
Aksoydan, Emine
Al Khenji, A.A.
FOOD MICROBIOLOGY
MEASLES (epidemiology)
Akyil, Rahsan
Al Kheraije, K.
CORONARY ARTERY BYPASS (psychology)
CAMELS
Al Adawi, Samir
Al Khiary, Hattan
THYROID FUNCTION TESTS
GANGLIONEUROMA (diagnosis)
Al Asiri, Khaled M.
Al Khyatt, Muzahim Kasem
WOUNDS AND INJURIES
LIVER FUNCTION TESTS
Al Azri, Ahmed
Al Kumaim, Mohamed
HERNIA, VENTRAL (etiology)
MOTOR ACTIVITY
Al Baghli, Amani A.
Al Kuwari, M.G.
AMINO ACIDS (urine)
MEASLES (epidemiology)
Al Barki, Ahmed
Al Lamki, Lamk
CANTHARIDIN (poisoning)
ACCIDENTS, TRAFFIC (mortality)
STRESS, PSYCHOLOGICAL
Al Binali, Ali M.
Al Lamki, Neela
CANTHARIDIN (poisoning)
ESOPHAGEAL FISTULA (radiography)
Al Busaidi, Zakiya Q.
Al Lawati, Hadia
SOMATOFORM DISORDERS
THYROID FUNCTION TESTS
Al Dabal, Badria K.
Al Mahrouqi, Badriya
STRESS, PSYCHOLOGICAL (epidemiology)
THYROID FUNCTION TESTS
Al Ezzy, Yehia
Al Mamari, Ali S.
MOTOR ACTIVITY
DIABETES MELLITUS, TYPE 2 (genetics)
Al Fadhli, Mariam
Al Marhoon, Mohammed S.
HYPERPARATHYROIDISM (diagnosis)
KIDNEY NEOPLASMS (diagnosis)
Al Faleh, Khalid M.
Al Muharrmi, Zakariya
SEPSIS (epidemiology)
INFLUENZA A VIRUS, H1N1 SUBTYPE
Al Fifi, Suliman
Al Mutairi, Ghaida'a F.
CANTHARIDIN (poisoning)
AMINO ACIDS (urine)
Al Futaisi, Amna
ATTENTION DEFICIT DISORDER WITH
HYPERACTIVITY (diagnosis)
Al Mutairi, Haya A.
Al Hadi, Hafidh
Al Mutairi, Sara A.
BUNDLE-BRANCH BLOCK (etiology)
CORONARY ANGIOGRAPHY (methods)
MENTAL RETARDATION (psychology)
MENTAL RETARDATION (psychology)
Al Naamani, Rahma
Al Hadithi, Tariq S.
BURNS (epidemiology)
ATTENTION DEFICIT DISORDER WITH
HYPERACTIVITY (diagnosis)
Al Hamdani, Aisha
Al Qadhi, Hani
THYROID NEOPLASMS (pathology)
STRONGYLOIDIASIS (diagnosis)
HERNIA, VENTRAL (etiology)
Al Riyami, Fatma
Al Harby, Saleh
DIABETES MELLITUS, TYPE 2 (genetics)
HEARING
Al Saadi, Amal
Al Haroon, Sawsan S.
THYROTOXICOSIS (radiotherapy)
CELIAC DISEASE (diagnosis)
Al Sajee, Dhuha M.A.
Al Harthi, Abdullah
STRONGYLOIDIASIS (diagnosis)
HERNIA, VENTRAL (etiology)
Al Saleh, Jamal
Al Hashami, Hilal
BEHCET SYNDROME
ACROCALLOSAL SYNDROME
Al Saqri, Badriya
Al Husaynei, Ahmed Jasim
ESOPHAGEAL FISTULA (radiography)
HYPERPROLACTINEMIA (drug therapy)
Al Shafaee, Mohammed
Al Kataan, Mohammad Abdul Ghffoor
THYROID FUNCTION TESTS
LIVER FUNCTION TESTS
94 IMEMR Current Contents
Author Index
Al Shaqsi, Asila
Ali, Seham A.
THYROID FUNCTION TESTS
AMINO ACIDS (urine)
Al Sharbati, Marwan
Ali, Y.
ATTENTION DEFICIT DISORDER WITH
HYPERACTIVITY (diagnosis)
EPILEPSY (surgery)
Aliasgarzadeh, Akbar
Al Shujairi, Tariq A.
NEOPLASMS (epidemiology)
POLYCYSTIC OVARY SYNDROME (drug
therapy)
Al Shwaikh, Arwa M.
Alireza, Yagoubi
BETA-LACTAMS
HEART DEFECTS, CONGENITAL (surgery)
Al Sowielem, Latifa
Alizadeh, Shaban
STRESS, PSYCHOLOGICAL (epidemiology)
TRIGONELLA
Al Sumait, Basel
Alkhalaf, Abdullah N.
HYPERPARATHYROIDISM (diagnosis)
MYCOPLASMA (isolation and purification)
Al Tahieneh, Amal S.
Almaghrabi, Lamia Hasan
GLUCAGONOMA (diagnosis)
LARYNGEAL NEOPLASMS (diagnosis)
Al Tawil, Namir G.
Alotaibi, Hend
BURNS (epidemiology)
HEPATITIS C ANTIBODIES
Al Wabel, N.A.
Alsaif, Fahed
PLANTS, MEDICINAL
HEPATITIS C ANTIBODIES
Al Wahaibi, Khalifa
Alshamary, H.
HERNIA, VENTRAL (etiology)
MYCOPLASMA (isolation and purification)
Al Wardy, Nadia
Alshishtawy, Moeness
EDUCATION, MEDICAL
HEALTH MANPOWER
Al Wardy, Nadia M.
Alshishtawy, Moeness M.
EDUCATION, MEDICAL, UNDERGRADUATE
DELIVERY OF HEALTH CARE
Al Yahla, O.A.
Altun, Insaf
MEASLES VACCINE (immunology)
BODY FLUIDS
Al Zaidi, Rashid
Alvavinejad, Pooyan
ATTENTION DEFICIT DISORDER WITH
HYPERACTIVITY (diagnosis)
OSTEOMA, OSTEOID (diagnosis)
Aman, Syed Faisal
Alavi, Seyed Mohammad
FOOD-DRUG INTERACTIONS
MENINGITIS, BACTERIAL (cerebrospinal fluid)
Amara, Amro A.
Alavian, Seyed Moayed
LEUKOEYTES (physiology)
INTERFERON ALFA-2A (therapeutic use)
Ambreen, Tahira
Alazri, Faisal
INFECTION CONTROL
CLASSICAL LISSENCEPHALIES AND
SUBCORTICAL
Amin, R.M.
DISEASE MANAGEMENT
Aldabbagh, Ali Abdulrazak
ECHINOCOCCOSIS, HEPATIC (complications)
Aminiarr, Amir
URINARY BLADDER NEOPLASMS (genetics)
Aldhawi, Zaid Muhammad
LARYNGEAL NEOPLASMS (diagnosis)
Aminsharifi, Alireza
URINARY BLADDER NEOPLASMS (genetics)
Alfadhli, Eman
EDUCATION, MEDICAL
Amna, A.
ERYTHROCYTE INDICES
Alfutaisi, Amna
CLASSICAL LISSENCEPHALIES AND
SUBCORTICAL
Anjum, F.
Alhadi, Hafidh A.
Ansari, Mansoor
FATTY ACID-BINDING PROTEINS (diagnostic
use)
MENINGIOMA (pathology)
ERYTHROCYTE INDICES
Ansari, Munawar Alam
Ali, Javed
BEVERAGES (microbiology)
RHINITIS, ALLERGIC, SEASONAL (drug
therapy)
Ali, S.M. Inkisar
Ansari, Noor Alam
COMMUNICATION
RHINITIS, ALLERGIC, SEASONAL (drug
therapy)
95 IMEMR Current Contents
Author Index
Antakly, M.C.
Aziz, Mona
MUPIROCIN (therapeutic use)
MYELODYSPLASTIC SYNDROMES (diagnosis)
Anwar, Adnan
Azooz, Faika A.
HUMERAL FRACTURES (surgery)
CELL PHYSIOLOGICAL PHENOMENA
Anwar, E.
Azoury, F.
MEDICAL RECORDS
GRAVES OPHTHALMOPATHY (radiotherapy)
Anwar, Muhammad
Bachar, Sitesh C.
TUBERCULOSIS, MENINGEAL (diagnosis)
PLANT EXTRACTS (pharmacology)
Ara, Iffat
Badawy, Abdulla
ANTIDEPRESSIVE AGENTS (pharmacology)
ANTIDEPRESSIVE AGENTS (pharmacology)
Arab, Maliheh
Bagheri, Neda
ADNEXAL DISEASES (ultrasonography)
MENINGIOMA (pathology)
Arab, Seyedeh Elham
Baglar, Leila
DERMATOMYCOSES (epidemiology)
POLYCYSTIC OVARY SYNDROME (drug
therapy)
Arabi, Abdessamad
Bahoor, F.
MYELOPROLIFERATIVE DISORDERS
BREAST NEOPLASMS (etiology)
Ardjmand, Ali Reza
Bahram, Qaderi
TRIGONELLA
HEART DEFECTS, CONGENITAL (surgery)
Arefi, Sh.
BREAST NEOPLASMS (etiology)
Bahrami, Amir
Arif, Khurrum
POLYCYSTIC OVARY SYNDROME (drug
therapy)
VESICOVAGINAL FISTULA (etiology)
Baig, Mirza Tasawer
ALKALOIDS (isolation and purification)
Arif, Muhammad
RETINOBLASTOMA (ultrasonography)
Bakir, Talal M.
HEPATITIS C ANTIBODIES
Arowojolu, A.O.
CONTRACEPTION
Balbisi, Amal
HEPATITIS C ANTIBODIES
Arslan, Sevban
PATIENT SATISFACTION
Baltaci, Abdulkerim Kasim
MELATONIN (administration and dosage)
Asadi, S.
BREAST NEOPLASMS (etiology)
Bamdad Moghadam, R.
Asgary, S.
PREGNANT WOMEN
ANTICHOLESTEREMIC AGENTS (therapeutic
use)
Banerjee, Yajnavalka
SNAKE VENOMS (history)
Ata, Mahmoodpoor
Banji, David
HEART DEFECTS, CONGENITAL (surgery)
PLANTS, MEDICINAL
Atef, Zayed A.
Banji, Otilia J.F.
MOTOR ACTIVITY
PLANTS, MEDICINAL
Awadalla, Amira A.
HYPERTENSION, RENOVASCULAR
(complications)
Bano, Samina
Ayoubi, Ayman
Barati, M.
GANGLIONEUROMA (diagnosis)
POLYPS (pathology)
Ayranci, Unal
Barbour, B.
UROLOGICAL MANIFESTATIONS
DYSMENORRHEA (epidemiology)
OBESITY (complications)
ANTIDEPRESSIVE AGENTS (pharmacology)
Barkia, A.
Azad, Rahmani
SCHISTOSOMIASIS (history)
HEART DEFECTS, CONGENITAL (surgery)
Barkia, H.
Azar, Maryam Razzaghy
SCHISTOSOMIASIS (history)
BONE DENSITY
Barzegar, Mohammad
Azeez, Abiodun Luqman
GUILLAIN-BARRE SYNDROME (microbiology)
URINARY DIVERSION (methods)
Basaleem, H.O.
Azhar, Iqbal
DISEASE MANAGEMENT
ALKALOIDS (isolation and purification)
96 IMEMR Current Contents
Author Index
Bashi, Ahmed Yahya Dallal
Chouairy, Camil J.
LIVER FUNCTION TESTS
CARCINOMA, SMALL CELL (pathology)
Bataclan, Maria F.
Citlik, Seyhan
ACROCALLOSAL SYNDROME
INTERVERTEBRAL DISK DISPLACEMENT
(therapy)
Bayat Movahed, S.
D'Souza, Reshma
ORAL HEALTH
OBESITY (epidemiology)
Bayoumi, Riad
Daneshbod, Yahya
SNAKE VENOMS (history)
MENINGIOMA (pathology)
Becerra Posada, Francisco
Danoei, S. Momeni
HEALTH SERVICES RESEARCH
ORTHODONTICS, INTERCEPTIVE (education)
Behnava, Bita
Dargahi, Hosejn
INTERFERON ALFA-2A (therapeutic use)
TRIGONELLA
Bekadja, M.A.
Dawood, Sami
MYELOPROLIFERATIVE DISORDERS
CANTHARIDIN (poisoning)
Belaluddin, Md.
Deghady, Akram
LEISHMANIASIS, VISCERAL (congenital)
HEPATITIS C, CHRONIC
Belghyti, D.
Delamarche, Paul
SCHISTOSOMIASIS (history)
BODY MASS INDEX
Bener, Ozgun
Devi, Kshama
FOOD MICROBIOLOGY
PPAR GAMMA (agonists)
Bererhi, Haddia
THYROID NEOPLASMS (pathology)
Dhakam, Sajid
Bin Zaal, Afra A.
ANGIOPLASTY, TRANSLUMINAL,
PERCUTANEOUS CORONARY
OBESITY (epidemiology)
Dikshit, Mohan B.
ACCIDENTS, AVIATION
Biria, M.
DENTAL DEVICES, HOME CARE
Dilmaghanizadeh, M.
PREGNANT WOMEN
Biswas, Mrinal
CARCINOMA, DUCTAL, BREAST (pathology)
Dilnawaz, Mansoor
NECROBIOTIC DISORDERS (diagnosis)
Bonyadi, Mohammad Reza
GUILLAIN-BARRE SYNDROME (microbiology)
Dinani, N. Jafari
ORTHODONTICS, INTERCEPTIVE (education)
ANTICHOLESTEREMIC AGENTS (therapeutic
use)
Brahimi, M.
Doi, Suhail A.R.
MYELOPROLIFERATIVE DISORDERS
HYPERPARATHYROIDISM (diagnosis)
Breizat, Abdel Hadi
Doleh, Wafa F.
GLUCAGONOMA (diagnosis)
BEHCET SYNDROME
Butt, Amir Mehmood
Dowod, Tarek Abdel Hameed Mostafa
ANODONTIA
TUMOR LYSIS SYNDROME (etiology)
Cantekin, Isin
Durairaj, Vikram D.
PATIENT SATISFACTION
SURGERY, COMPUTER-ASSISTED
Celik, Ilham
Ebong, P.
MELATONIN (administration and dosage)
PLANT EXTRACTS (pharmacology)
Ceyhan, Ozlem
Efange, Simon M.N.
MULTIPLE SCLEROSIS
APIACEAE
Chand, Gian
Ehsan, Ayesha
RHINITIS, ALLERGIC, PERSNNIAL (therapy)
MYELODYSPLASTIC SYNDROMES (diagnosis)
Chaudhry, Tanveer Anjum
Ehssan, Noha A.
BLEPHAROPHIMOSIS
METFORMIN (therapeutic use)
Chikezie, Paul C.
Eid, Mohamed
METHEMOGLOBIN
INTESTINAL DISEASES (diagnosis)
Chopra, Pradeep
Einolahi, Nahid
REFERRAL AND CONSULTATION
TRIGONELLA
Boushehri, S. Ghodsi
97 IMEMR Current Contents
Author Index
Ejaz, Muzamil Shabana
Ensafdararr, Mohammad Reza
COMMUNICATION
LIPOMA (diagnosis)
Ekim, Hasan
Eseyin, O.A.
CORONARY ARTERY DISEASE
PLANT EXTRACTS (pharmacology)
Ekram, A.R.M. Saifuddin
Eshghi, Peyman
LEISHMANIASIS, VISCERAL (congenital)
VENOUS THROMBOSIS (genetics)
El Agawany, A.A.
Eslami, Ziae
MASTITIS (Microbiology)
HYDROXYUREA (therapeutic use)
El Awady, Hatem E.
Esmerian, Maria O.
TIMOLOL (therapeutic use)
PHARMACOGENETICS
El Battawy, E.H.
Essa, Ebtessam A.
MYCOBACTERIUM BOVIS (isolation and
purification)
IBUPROFEN (chemistry)
Esteghamati, A.
El Gamal, Ali A.
HEPATITIS B VACCINES
ALGAE
Etemadi, Sahar
El Ghandour, Ashraf
HEART DEFECTS, CONGENITAL (surgery)
LEUKEMIA, LYMPHOID (epidemiology)
Eyong, E.U.
El Ghazali, G.
PLANT EXTRACTS (pharmacology)
MEASLES VACCINE (immunology)
Fahim, A. Shah
El Hage, Rawad
HEARING
BODY MASS INDEX
Fahmy, Basem A.G.
El Maghrbi, A.A.
CATFISHES
THEILERIA (Parasitology)
FOXES (Parasitology)
Faidulla, Rawand M.
BURNS (epidemiology)
El Makhzangy, Ibrahim Mohamed
MENORRHAGIA (therapy)
Fardiazar, Z.
PREGNANT WOMEN
El Nafees, Raouf
LENSES, INTRAOCULAR
Farook, Seyad M.S.
SNAKE VENOMS (history)
El Sawy, Mohamed M.
HYPERTENSION, RENOVASCULAR
(complications)
Fathi, Alaa Mohamed
El Saygh, Mervat
Fattahi, Mohammad Javad
LEUKEMIA, LYMPHOID (epidemiology)
ANTIGENS, CD95 (blood)
El Shafie, Kawther
Fazah, Abdallah
THYROID FUNCTION TESTS
BODY MASS INDEX
El Shayeb, Ayman
Fida, Mubassar
HEPATITIS C, CHRONIC
TOOTH (growth and development)
El Sogheer, A.
Firthouse, P.U. Mohamed
PRENATAL CARE
CYCLOOXYGENASE 2 INHIBITORS
(administration and dosage)
INTESTINAL DISEASES (diagnosis)
Elizee, Pegah Karimi
INTERFERON ALFA-2A (therapeutic use)
Foster, Ken
SCHOOLS, MEDICAL
Elkhamary, Sahar M.
GANGLIONEUROMA (diagnosis)
Fox, Keith A.A.
Elkordy, Amal A.
FATTY ACID-BINDING PROTEINS (diagnostic
use)
IBUPROFEN (chemistry)
Freeman, Helen
Elmacioglu, Funda
ACCIDENTS, TRAFFIC
FOOD MICROBIOLOGY
Fudllalah, Ferial M.N.
Elshafie, Ghazi A.
CATFISHES
HERNIA, VENTRAL (etiology)
Gaafar, Walid
Elshafie, Omayma T.
LENSES, INTRAOCULAR
DIABETES MELLITUS, TYPE 2 (genetics)
THYROID NEOPLASMS (pathology)
Gad, Mohamed A.
TIMOLOL (therapeutic use)
Ensafdararr, Ahmad
LIPOMA (diagnosis)
98 IMEMR Current Contents
Author Index
Gad, Mohamed Z.
Greenson, Joel R.
METFORMIN (therapeutic use)
PANCREATIC NEOPLASMS (genetics)
Gamal Eldin, Omneya Ahmed
Gul, Nur Dilek
INTESTINAL DISEASES (diagnosis)
TRACHEOSTOMY
Ganguly, Shyam S.
Gul, Tamjeed
THYROID FUNCTION TESTS
MYXOMA (diagnosis)
Garjani, Alireza
Gumrukcuoglu, Hasan Ali
CARNITINE (pharmacology)
CORONARY ARTERY DISEASE
Gatsing, Donatien
Gunes, Yilmaz
APIACEAE
CORONARY ARTERY DISEASE
Gauhar, Shahnaz
Gupta, Anish
FLUOROQUINOLONES (pharmacology)
ORBIT (surgery)
Ghaderi, Abbas
Haan, Sylvia
URINARY BLADDER NEOPLASMS (genetics)
HEALTH SERVICES RESEARCH
Ghafari, Mahmoud
Habib, Adnan
ANTINEOPLASTIC AGENTS, PHYTOGENIC
STRESS, PSYCHOLOGICAL
Ghafarzadeh, Masoumeh
Habib, F.
SOYBEANS
PRENATAL CARE
Ghahremoni, Y.
Habibagahi, Mojtaba
ORTHODONTICS, INTERCEPTIVE (education)
ANTIGENS, CD95 (blood)
Ghandforoush Sattari, M.
Habibullah, Sultana
PREGNANT WOMEN
INJECTIONS
Ghandour, Lilian A.
Haddad, F.
SUBSTANCE-RELATED DISORDERS
(epidemiology)
MUPIROCIN (therapeutic use)
Hage, Nasr C.
Ghanem, Asaad A.
STUDENTS, MEDICAL
TIMOLOL (therapeutic use)
Hagr, Abdulrahman A.
Ghannem, Hassen
EAR, INNER (surgery)
HEALTH SERVICES RESEARCH
Haider, G.
Ghazal, George Y.
ERYTHROCYTE INDICES
CARCINOMA, SMALL CELL (pathology)
Hajian Tilaki, K.O.
Ghiet, Mansour H.
OVERWEIGHT (epidemiology)
METFORMIN (therapeutic use)
Hajibeigi, Bashir
Ghorbani Haghjo, Amir
INTERFERON ALFA-2A (therapeutic use)
CARNITINE (pharmacology)
Halawani, Mona
Ghostine, B.
HEPATITIS C ANTIBODIES
EPILEPSY (surgery)
Halith, S. Mohamed
Gitay, Mehnaz
ANTIDEPRESSIVE AGENTS (pharmacology)
CYCLOOXYGENASE 2 INHIBITORS
(administration and dosage)
Gomaa, Sekina A.
Hamad, Adeel
HYPERTENSION, RENOVASCULAR
(complications)
FISSURE IN ANO (surgery)
Hamdi, K.
Gondal, Mudassar
BREAST NEOPLASMS (etiology)
VESICOVAGINAL FISTULA (etiology)
Hanafi, M.I.
Gooda, M. Rafique
PRENATAL CARE
POSTOPERATIVE HEMORRHAGE (prevention
and control)
Hanafi, Manal Ibrahim
Goris, Songul
EDUCATION, MEDICAL
MEDICINE, TRADITIONAL
MULTIPLE SCLEROSIS
Haque, Md. Azizul
Gouya, M.M.
LEISHMANIASIS, VISCERAL (congenital)
HEPATITIS B VACCINES
Harbi, Khaled B.
Gowri, Vaidyanathan
MYCOPLASMA (isolation and purification)
TRIAL OF LABOR
99 IMEMR Current Contents
Author Index
Haroun, Bakry M.
Hussain, Arshad
LEUKOEYTES (physiology)
BEVERAGES (microbiology)
Hasan, Syed Muhammmad Farid
Hussain, Mehmood
FOOD-DRUG INTERACTIONS
ANODONTIA
Hashad, M.
Hussain, Riaz
MYCOPLASMA (isolation and purification)
STOMACH (abnormalities)
Hashem, Ashraf Ahmed Hussein
Hussein, M.M.
TUMOR LYSIS SYNDROME (etiology)
MASTITIS (Microbiology)
Hashemi, Azamsadat
Hussein, Mohammed A.
HYDROXYUREA (therapeutic use)
CHOLESTASIS (etiology)
Hashemi, Seyed Basir
Hussein, Samir
HEAD AND NECK NEOPLASMS (drug therapy)
THYROID NEOPLASMS (pathology)
Hashemi, Seyed Baslr
Hussien, M.M.
ANTIGENS, CD95 (blood)
UTERINE PROLAPSE (surgery)
Hashemieh, Mojgan
Ibrahim, Hanan M.
ADNEXAL DISEASES (ultrasonography)
CAMELS (Microbiology)
Hashemilar, Mazyar
Iffat, Wajiha
GUILLAIN-BARRE SYNDROME (microbiology)
FLUOROQUINOLONES (pharmacology)
Hashim, Hasnah
Ijsselmuiden, Carel
CARCINOMA, DUCTAL, BREAST (pathology)
HEALTH SERVICES RESEARCH
Hassan, Abdul R.M.
Ikram, Aamer
HEARING
INFECTION CONTROL
Hassan, Fathelrahman Mahdi
Ikramullah
ABO BLOOD-GROUP SYSTEM
CELL DIFFERENTIATION (drug effects)
Hassan, Fouzia
Ilkhan, S.
FOOD-DRUG INTERACTIONS
POLYPS (pathology)
Hassan, Mohamad A.
Imran, Muhammad Babar
LEUKOEYTES (physiology)
INFLUENZA A VIRUS, H1N1 SUBTYPE
Haycox, A.
Iqbal, Javaid
DRUG PRESCRIPTIONS
MEDICATION ERRORS
PHYSICIAN'S PRACTICE PATTERNS
WOUNDS AND INJURIES
Iqbal, M.
MEDICAL RECORDS
Hayek, G.
MUPIROCIN (therapeutic use)
Irfan, Muhammad
TUBERCULOSIS, PULMONARY (drug therapy)
Hegab, Hassan Mansour
MENORRHAGIA (therapy)
Islam, Rafiqul
PRENATAL CARE (psychology)
Heidarpour, Majid
CARCINOMA, BASAL CELL (pathology)
Islam, Rajakul
CARCINOMA, DUCTAL, BREAST (pathology)
Heidarpour, Mitra
CARCINOMA, BASAL CELL (pathology)
Ismail, Hashimah
FOREIGN BODIES (complications)
Helwa, Iman
HEALTH SERVICES RESEARCH
Jabbour, H.
MUPIROCIN (therapeutic use)
Holmboe Ottesen, G.
ANEMIA (epidemiology)
DIET
Jabbour, K.
Hosni, M.M.
Jaberipour, Mansooreh
THEILERIA (Parasitology)
FOXES (Parasitology)
ANTIGENS, CD95 (blood)
MUPIROCIN (therapeutic use)
Jacob, Christophe
Hoycox, A.
BODY MASS INDEX
DRUG PRESCRIPTIONS
Jafari, Fahim Haider
Huijer, Huda Abu Saad
OLFACTORY BULB (ultrastructure)
PAIN (etiology)
Jafarnia, N.
Hunt, B.P.
BREAST NEOPLASMS (etiology)
SMOKING (epidemiology)
100 IMEMR Current Contents
Author Index
Jaffer, Yasmin
Kausar, Shabana
CONGENITAL ABNORMALITIES (epidemiology)
ENTAMOEHA HISTOLYTICA (isolation and
purification)
Jahangeer, Ashraf
Kaya, Oktay
STRESS, PSYCHOLOGICAL
MELATONIN (administration and dosage)
Jahanmehr, Seyed Abdol Hamid
Keikhaei, Bijan
TRIGONELLA
ANEMIA, IRON-DEFICIENCY (diagnosis)
Jain, Rajeev
ATTENTION DEFICIT DISORDER WITH
HYPERACTIVITY (diagnosis)
CLASSICAL LISSENCEPHALIES AND
SUBCORTICAL
TRIAL OF LABOR
Keshav, B.R.
Jambart, S.
Keshvari, Maryam
GRAVES OPHTHALMOPATHY (radiotherapy)
INTERFERON ALFA-2A (therapeutic use)
Jan, Iftikhar Ahmad
Khabir, Ahmad
VESICOVAGINAL FISTULA (etiology)
BLEPHAROPHIMOSIS
Jastaneiah, Sabah S.
Khalaf, Ban H.
EYE FOREIGN BODIES
POLYCYSTIC OVARY SYNDROME
Javidnia, Ali
Khaleghian, Ali
CARNITINE (pharmacology)
ANTINEOPLASTIC AGENTS, PHYTOGENIC
Jawaid, Shaukat Ali
Khalid, Ayesha
PUBLICATIONS (standards)
PERICARDITIS, CONSTRICTIVE (microbiology)
Jayaprakash, S.
Khalid, Imran
CYCLOOXYGENASE 2 INHIBITORS
(administration and dosage)
CARCINOMA, DUCTAL, BREAST (pathology)
ALBINISM, OCULOCUTANEOUS
Keshtkar, A.A.
HEPATITIS B VACCINES
Khalid, Mirza Umair
Jenabzade, Ali Reza
BLEPHAROPHIMOSIS
HYDROXYUREA (therapeutic use)
Khalife, Ali
Junejo, Sameen Afzal
CARCINOMA, BASAL CELL (pathology)
RHINITIS, ALLERGIC, SEASONAL (drug
therapy)
Khalil, A.A.Y.
Kakal, Fatima
MASTITIS (Microbiology)
UTERINE PROLAPSE (surgery)
RH-HR BLOOD-GROUP SYSTEM (genetics)
Khalil, M.K.M.
Kamil, Muhammad
MEASLES VACCINE (immunology)
CARCINOMA, DUCTAL, BREAST (pathology)
Khamis, Nadzman
Kamona, Atheel
FOREIGN BODIES (complications)
ESOPHAGEAL FISTULA (radiography)
Khan, Aizaz Saleem
Kantharaju, K.K.
HUMERAL FRACTURES (surgery)
HEARING
Khan, Mansoor
Karadag, Ayise
APPENDECTOMY (methods)
TRACHEOSTOMY
Khan, Muhammad Irshad
Karam, Elie G.
LARYNGEAL NEOPLASMS (diagnosis)
SUBSTANCE-RELATED DISORDERS
(epidemiology)
Khan, Rafeeq Alam
PLANTS, MEDICINAL (toxicity)
Karkouri, Mehdi
PANCREATIC NEOPLASMS (genetics)
Khan, Rashid M.
Karle, Hans
SCHOOLS, MEDICAL
INTUBATION, INTRATRACHEAL (adverse
effects)
APNEA
Karraz, Samer A.
Khan, Shaheen
AMINO ACIDS (urine)
FATTY LIVER
Kaul, Naresh
Khan, Zaka U.
INTUBATION, INTRATRACHEAL (adverse
effects)
APNEA
WOUNDS AND INJURIES
Khanam, Salma
PPAR GAMMA (agonists)
Kaur, Gurjeet
CARCINOMA, DUCTAL, BREAST (pathology)
101 IMEMR Current Contents
Author Index
Khandekar, Rajiv
Kundi, Niamat Ullah Khan
CONGENITAL ABNORMALITIES (epidemiology)
HEARING
RETINOBLASTOMA (ultrasonography)
Lafta, Riyadh K.
Khannam, Merina
NEOPLASMS (epidemiology)
POSTPARTUM HEMORRHAGE (prevention and
control)
Lankarani, Kamran Bagheri
Khare, Sumit
INTERFERON ALFA-2A (therapeutic use)
INFLUENZA A VIRUS, H1N1 SUBTYPE
ORBIT (surgery)
Lashari, M.H.
Khater, S.
GRAVES OPHTHALMOPATHY (radiotherapy)
ENTAMOEHA HISTOLYTICA (isolation and
purification)
Khawaja, Nuzhat Parveen
Law, M.
MISOPROSTOL (administration and dosage)
SURVIVAL ANALYSIS
Khemani, Asudo Mal
Lee, Hae Young
RHINITIS, ALLERGIC, PERSNNIAL (therapy)
CELL DIFFERENTIATION (drug effects)
Khezri, Abdolaziz
Little, Brian
URINARY BLADDER NEOPLASMS (genetics)
PHACOEMULSIFICATION (adverse effects)
Khilji, Muhammad Saad
Maalouf, Wadih E.
OLFACTORY BULB (ultrastructure)
SUBSTANCE-RELATED DISORDERS
(epidemiology)
Khoja, T.
Maarawi, J.
DRUG PRESCRIPTIONS
MEDICATION ERRORS
PHYSICIAN'S PRACTICE PATTERNS
EPILEPSY (surgery)
Madani, H.
Khosravi, R.
ORAL HEALTH
ANTICHOLESTEREMIC AGENTS (therapeutic
use)
Khozai, Arash
Madi Jebara, S.
LIPOMA (diagnosis)
MUPIROCIN (therapeutic use)
Kilani, Hashem
Magzoub, M.A.
BODY COMPOSITION
DRUG PRESCRIPTIONS
PHYSICIAN'S PRACTICE PATTERNS
Kilic, Mehmet
Mahfoozpour, Soad
MELATONIN (administration and dosage)
HEALTH PERSONNEL
Kim, Myeong Ok.
Mahmood, Isam Hamo
CELL DIFFERENTIATION (drug effects)
HYPERPROLACTINEMIA (drug therapy)
Kinj, Nadeem
Mahmood, Nasir
SMOKING (epidemiology)
ALBINISM, OCULOCUTANEOUS
Kishk, Hanem
Mahmood, Zafar Alam
LENSES, INTRAOCULAR
ALKALOIDS (isolation and purification)
Kiyak, Emine
INTERVERTEBRAL DISK DISPLACEMENT
(therapy)
Mahmoud, Samadi
Kotb, Hesham T.
Mahzoni, P.
HYPERTENSION, RENOVASCULAR
(complications)
ANTICHOLESTEREMIC AGENTS (therapeutic
use)
Koul, Roshan
Makdoom, Naeem
CLASSICAL LISSENCEPHALIES AND
SUBCORTICAL
MEDICINE, TRADITIONAL
HEART DEFECTS, CONGENITAL (surgery)
Makheja, Kirpal Das
Koura, Manal R.
HEPATITIS C ANTIBODIES (immunology)
STRESS, PSYCHOLOGICAL (epidemiology)
Makki, Suhair M.
Krdoghli, Najwa F.
STRESS, PSYCHOLOGICAL (epidemiology)
MIOSIS (prevention and control)
Malekafzali, B.
Krishnan, Lalitha
DENTAL DEVICES, HOME CARE
ACROCALLOSAL SYNDROME
Malik, Humaira Zaman
Kumar, Sanjay
MISOPROSTOL (administration and dosage)
RHINITIS, ALLERGIC, PERSNNIAL (therapy)
Mane, Pratibha
Kumar, Susheel
HEARING
HEPATITIS C ANTIBODIES (immunology)
102 IMEMR Current Contents
Author Index
Marjani, Hajiamin
Moghaddanr, Siavosh Nasseri
ESOPHAGEAL NEOPLASMS (epidemiology)
ESOPHAGEAL NEOPLASMS (epidemiology)
Mashayekhi, S.O.
Mogulkoc, Rasim
PREGNANT WOMEN
MELATONIN (administration and dosage)
Masihi, S.
Mogzoub, M.A.
POLYPS (pathology)
MEDICATION ERRORS
Masood, Shahla
Mohamad, Hazama
BREAST NEOPLASMS
FOREIGN BODIES (complications)
Masters, Ken
Mohamad, Irfan
PHYSICIAN-PATIENT RELATIONS
AIRCRAFT
FOREIGN BODIES (complications)
Mohamad, Shatha Hani
Matapady, Harish Nairy
HYPERPROLACTINEMIA (drug therapy)
PLANT GUMS (administration and dosage)
Mohamed, Aida Mohey
Mathew, Mariam
MEDICINE, TRADITIONAL
ACROCALLOSAL SYNDROME
Mohamed, Azza Hassan
Mazhar, Attaullah
TUBERCULOSIS, MENINGEAL (diagnosis)
HYPERTENSION, RENOVASCULAR
(complications)
Mbah, James A.
Mohammadi, Akram Ghara
APIACEAE
ADNEXAL DISEASES (ultrasonography)
Meerkhan, Suaad A.
Mohammadi, Sadollah
CELL PHYSIOLOGICAL PHENOMENA
CARNITINE (pharmacology)
Mehany, Shaaban A.
Mohammadianpanah, Mohammad
CENTRAL SEROUS CHORIORETINOPATHY
(drug therapy)
RETINAL VEIN OCCLUSION (drug therapy)
MENINGIOMA (pathology)
Mohammed, Mahmood J.
ALBINISM, OCULOCUTANEOUS
Mehdinasab, Seyed Abdol Hossein
OSTEOMA, OSTEOID (diagnosis)
Mohammed, Nagi H.S.
DIABETES MELLITUS, TYPE 2 (genetics)
Mehfooz, Zeeshan
TUBERCULOSIS, PULMONARY (drug therapy)
Mohammed, Nuruddin
RH-HR BLOOD-GROUP SYSTEM (genetics)
Memon, Abdul Sattar
FISSURE IN ANO (surgery)
Mohiuddin, Ejaz
PLANT EXTRACTS (pharmacology)
Memon, Ashfaque
NUTRITION ASSESSMENT
Mojdehkar, Reyhaneh
HEALTH PERSONNEL
Memory, N.
ORAL HEALTH
Monago, Comfort C.
METHEMOGLOBIN
Menassa, L.
EPILEPSY (surgery)
Mosalaei, Ahmad
Meo, Sultan Ayoub
MENINGIOMA (pathology)
HEAD AND NECK NEOPLASMS (drug therapy)
INFLUENZA A VIRUS, H1N1 SUBTYPE
Moshiri, Naser
Mikki, N.
MENINGITIS, BACTERIAL (cerebrospinal fluid)
ANEMIA (epidemiology)
Mossad, A.A.
Miri, Seyyed Mohammad
INTERFERON ALFA-2A (therapeutic use)
MYCOBACTERIUM BOVIS (isolation and
purification)
Mirza, Kamran Masood
Mourad, Khaled M.
ANODONTIA
CENTRAL SEROUS CHORIORETINOPATHY
(drug therapy)
RETINAL VEIN OCCLUSION (drug therapy)
Mirza, Meral
MULTIPLE SCLEROSIS
Mousavi, Seyed Abdollah
GANGRENE (etiology)
Mitri, Zahi
PHARMACOGENETICS
Moussa, Elie
BODY MASS INDEX
Moawad, Ashraf
LENSES, INTRAOCULAR
Moussa, R.
EPILEPSY (surgery)
Modarres, Aliakbar
BONE DENSITY
103 IMEMR Current Contents
Author Index
Mozaffarian, Valiolah
Naseem, Sajida
PLANT EXTRACTS (pharmacology)
INFECTION CONTROL
Mubarak, Iman Ibrahim
Naseer, Muhammad Imran
MEDICINE, TRADITIONAL
CELL DIFFERENTIATION (drug effects)
Muhammad, Iyad Naeem
Nasr, E.
FLUOROQUINOLONES (pharmacology)
GRAVES OPHTHALMOPATHY (radiotherapy)
Mumtaz, Yasmin
Nasr, E.A.
STRESS, PSYCHOLOGICAL
MYCOBACTERIUM BOVIS (isolation and
purification)
Mumtaz, Zara
Nasrolahi, Hamid
STRESS, PSYCHOLOGICAL
MENINGIOMA (pathology)
Munir, A.A.
Nasrolahi, Shahla
ERYTHROCYTE INDICES
HOMOCYSTEINE (drug effects)
Musaiger, Abdulrahman O.
Nazari, Hossain
OBESITY (epidemiology)
ANTINEOPLASTIC AGENTS, PHYTOGENIC
Musallam, Khaled M.
Neelakanthan, Punnuvella H.
NEOPLASMS (epidemiology)
APNEA
Muttikkal, Thomas
Negahban, Shahrzad
HYPERPARATHYROIDISM (diagnosis)
MENINGIOMA (pathology)
Naderi, Gh.
ANTICHOLESTEREMIC AGENTS (therapeutic
use)
Neghab, Nosrat
Nadjafi, L.
Nehme Nasr, D.
HEPATITIS B VACCINES
GRAVES OPHTHALMOPATHY (radiotherapy)
Nadrah, H.M.
Neyaz, Y.
MEASLES VACCINE (immunology)
DRUG PRESCRIPTIONS
MEDICATION ERRORS
PHYSICIAN'S PRACTICE PATTERNS
HOMOCYSTEINE (drug effects)
Naeimi, Sirous
URINARY BLADDER NEOPLASMS (genetics)
Ng'ambi, Dick
Nagarajan, M.
PHYSICIAN-PATIENT RELATIONS
CYCLOOXYGENASE 2 INHIBITORS
(administration and dosage)
Nhammi, H.
SCHISTOSOMIASIS (history)
Nahar, Shamsun
Niafar, Mitra
POSTPARTUM HEMORRHAGE (prevention and
control)
POLYCYSTIC OVARY SYNDROME (drug
therapy)
Najafi, Moslem
Niar, Raghunandan
CARNITINE (pharmacology)
HEARING
Najafipour, Farzad
POLYCYSTIC OVARY SYNDROME (drug
therapy)
Niazi, Saifullah Khan
Najeebullah
Nohra, G.
CELL DIFFERENTIATION (drug effects)
EPILEPSY (surgery)
Nakaya, Yutaka
Nooritajer, Maryam
ANTINEOPLASTIC AGENTS, PHYTOGENIC
PREGNANCY OUTCOME
Nakhaee, F.
Nozzal, Z.A.
SURVIVAL ANALYSIS
MEASLES (epidemiology)
Namdari, Mehrdad
Oguntibeju, O.O.
SOYBEANS
CONTRACEPTION
Naqvi, Baqar S.
Okais, N.
FOOD-DRUG INTERACTIONS
EPILEPSY (surgery)
Narayanacharyulu, R.
Omar, S.H.
PLANT GUMS (administration and dosage)
PLANTS, MEDICINAL
Nargis, Shamim Fatema
Omer, Hoda Gad
POSTPARTUM HEMORRHAGE (prevention and
control)
PANCREATIC NEOPLASMS (genetics)
INFECTION CONTROL
Omidvari, Shapour
MENINGIOMA (pathology)
104 IMEMR Current Contents
Author Index
Orakzai, Hazratullah
Rahman, M. Aminur
VESICOVAGINAL FISTULA (etiology)
PLANT EXTRACTS (pharmacology)
Oshagh, M.
Rahman, Mahfuzar
ORTHODONTICS, INTERCEPTIVE (education)
PRENATAL CARE (psychology)
Osifo, Osarumwense David
Rahman, Mosfequr
URINARY DIVERSION (methods)
PRENATAL CARE (psychology)
Othrub, Khaled
Rahmatullah, Mohammed
FOREIGN BODIES (complications)
PLANT EXTRACTS (pharmacology)
Oyabiyi, S.A.
Rajabi, Parvin
CONTRACEPTION
CARCINOMA, BASAL CELL (pathology)
Ozer, Nadiye
Ramzan, Afroze
CORONARY ARTERY BYPASS (psychology)
PATIENT SATISFACTION
NUTRITION ASSESSMENT
Rani, S.
Ozguven, H.D.
ERYTHROCYTE INDICES
PATERNITY
Rao, Nisar Ahmed
Ozlu, Zeynep Karaman
TUBERCULOSIS, PULMONARY (drug therapy)
PATIENT SATISFACTION
Rasheed, Khalid
Pal, Inam
PERICARDITIS, CONSTRICTIVE (microbiology)
ESOPHAGEAL NEOPLASMS (pathology)
Rasheed, Parveen
Pirzada, A.J.
STRESS, PSYCHOLOGICAL (epidemiology)
PLANT EXTRACTS (pharmacology)
Rathore, Altaf Hussain
Pojuhi, N.
STOMACH (abnormalities)
ORTHODONTICS, INTERCEPTIVE (education)
Rathore, Farhan
Pour, Kourosh Goudarzi
STOMACH (abnormalities)
VENOUS THROMBOSIS (genetics)
Ravichandran, Ramamoorthy
Prabhu, Prabhakara
THYROTOXICOSIS (radiotherapy)
PLANT GUMS (administration and dosage)
Raza, Syed Nusrat
Prithviraj, D.R.
HORNER SYNDROME (diagnosis)
ORBIT (surgery)
Razavi, A.
Qadeer, E.
OVERWEIGHT (epidemiology)
MEDICAL RECORDS
Rehana
Quresh, N.A.
FLUOROQUINOLONES (pharmacology)
MEDICATION ERRORS
DRUG PRESCRIPTIONS
Rehman, Rakhshanda
MISOPROSTOL (administration and dosage)
Qureshi, Asim
ESOPHAGEAL NEOPLASMS (pathology)
Rehman, Safia
MYXOMA (diagnosis)
Qureshi, N.A.
DRUG PRESCRIPTIONS
PHYSICIAN'S PRACTICE PATTERNS
Rezaian, Mostafa
Rabat, Z.M.
Rezaie, Marzieh
HORNER SYNDROME (diagnosis)
ANTINEOPLASTIC AGENTS, PHYTOGENIC
Rabbani, Syed Imam
Riaz, Azra
PPAR GAMMA (agonists)
PLANTS, MEDICINAL (toxicity)
Radnia, Nahid
Riazi, Gholam Hossein
HOMOCYSTEINE (drug effects)
ANTINEOPLASTIC AGENTS, PHYTOGENIC
Radwan, G.S.
Ritch, Robert
MYCOBACTERIUM BOVIS (isolation and
purification)
GLAUCOMA (complications)
TRIGONELLA
Rizk, T.
Raeburn, Sandy
EPILEPSY (surgery)
DIABETES MELLITUS, TYPE 2 (genetics)
Rizkalla, Esam H.
Rafi, Junaid
CATFISHES
VESICOVAGINAL FISTULA (etiology)
Rafsanjani, Khadijeh Arjmandi
BONE DENSITY
105 IMEMR Current Contents
Author Index
Rizvi, Shoaib Raza
Salloum, Ali N.
SKIN DISEASES, VESICULOBULLOUS
(diagnosis)
CARCINOMA, SMALL CELL (pathology)
Samaan, Samer F.
Rizvi, Syed
BETA-LACTAMS
TRIAL OF LABOR
Samadzadeh, H.
Robinson, Sara
ORAL HEALTH
PANCREATIC NEOPLASMS (genetics)
Samaha, E.
Rooh ul Muqim
EPILEPSY (surgery)
APPENDECTOMY (methods)
Samaha, H.A.
Roshandel, Gh.
HEPATITIS B VACCINES
MYCOBACTERIUM BOVIS (isolation and
purification)
Sabayarr, Behnam
Sarrafan, Nasser
INFLUENZA A VIRUS, H1N1 SUBTYPE
OSTEOMA, OSTEOID (diagnosis)
Sabee, M. S.M.
Satyanarayana, D.
INFECTION CONTROL
PLANT GUMS (administration and dosage)
Sabra, Ramzi
Sayed, Mohamed F.
PHARMACOGENETICS
CENTRAL SEROUS CHORIORETINOPATHY
(drug therapy)
Sadek, N.A.
Sayeda, Mohammed F.
HEPATITIS B SURFACE ANTIGENS (blood)
RETINAL VEIN OCCLUSION (drug therapy)
Sadiq, Saleem
SKIN DISEASES, VESICULOBULLOUS
(diagnosis)
Sayegh, J.
Sadjadi, Alireza
Sbeity, Zaher
ESOPHAGEAL NEOPLASMS (epidemiology)
GLAUCOMA (complications)
Sadr Eshkevari, P.S.
Scharawe, Hala I.
ORAL HEALTH
CAMELS (Microbiology)
Sadrossadat, Monjreh
Sedaghat, Sanaz
TRIGONELLA
HEAD AND NECK NEOPLASMS (drug therapy)
Saeed, Bashar Ali
Sedeek, A.M.
CELIAC DISEASE (diagnosis)
UTERINE PROLAPSE (surgery)
Safwat, El Sawy
Semnani, Shahryar
CAMELS (Microbiology)
ESOPHAGEAL NEOPLASMS (epidemiology)
Sahebpour, Alireza Alam
Shabana, Medhat
GANGRENE (etiology)
CANTHARIDIN (poisoning)
Saidi, D.
Shabbir, R.
MYELOPROLIFERATIVE DISORDERS
MEDICAL RECORDS
Sajjad Ur Rahman
Shabila, Nazar P.
PERINATAL MORTALITY
BURNS (epidemiology)
Salam, M.A.
Shafeh, Reem
LEISHMANIASIS, VISCERAL (congenital)
HEPATITIS C, CHRONIC
Salameh, P.
Shafie, Akram
OBESITY (complications)
HOMOCYSTEINE (drug effects)
Salamoun, Mariana M.
Shah, Sayed Ibrar Hussain
SUBSTANCE-RELATED DISORDERS
(epidemiology)
INFECTION CONTROL
STUDENTS, MEDICAL
Shahid, Anjum
Salaramoli, M.
NUTRITION ASSESSMENT
HEPATITIS B VACCINES
Shahmohammadi, Soheila
Saleem, Taimur
GANGRENE (etiology)
BLEPHAROPHIMOSIS
Shahriari, Mahdi
Saleh, Tarek Rashad
IRON (therapeutic use)
INTESTINAL DISEASES (diagnosis)
Shaikh, M. Zaman
Sallam, Mansour
DIABETES MELLITUS (prevention and control)
BUNDLE-BRANCH BLOCK (etiology)
CORONARY ANGIOGRAPHY (methods)
106 IMEMR Current Contents
Author Index
Shaikh, M.A.
Soliman, Amr S.
SMOKING (epidemiology)
PANCREATIC NEOPLASMS (genetics)
Shaikh, W.
Somani, Mehreen
PLANT EXTRACTS (pharmacology)
RH-HR BLOOD-GROUP SYSTEM (genetics)
Shamseddine, Ali I.
Soomro, Mir Muhammad
NEOPLASMS (epidemiology)
TUBERCULOSIS, PULMONARY (drug therapy)
Shanthamurthy, M.
Stigum, H.
PLANTS, MEDICINAL
ANEMIA (epidemiology)
Shariati, Mahmood
Strak, Sarkis K.
ANTIGENS, CD95 (blood)
CELIAC DISEASE (diagnosis)
Sharififar, Fariba
Sualeh, Mohammad
PLANT EXTRACTS (pharmacology)
ALKALOIDS (isolation and purification)
Sharma, Pradeep K.
Subrahmanayam, E.V.S.
INTUBATION, INTRATRACHEAL (adverse
effects)
PLANT GUMS (administration and dosage)
Sukhia, Rashna H.
Sharmin, Laila Shamima
TOOTH (growth and development)
LEISHMANIASIS, VISCERAL (congenital)
Suleiman, Yusuf M.
Shawkat, Ahmad M.
MIOSIS (prevention and control)
CENTRAL SEROUS CHORIORETINOPATHY
(drug therapy)
Suleri, Azam
Shawkata, Ahmad M.
POSTOPERATIVE HEMORRHAGE (prevention
and control)
RETINAL VEIN OCCLUSION (drug therapy)
Sultan, Intessar
Shehnaz, Syed I.
EDUCATION, MEDICAL
EDUCATION, MEDICAL
Sungur, Gonul
Shehri, Amer A.
MULTIPLE SCLEROSIS
CANTHARIDIN (poisoning)
Taba, Khalid
Sheikh, Irshad
HEPATITIS C, CHRONIC
POSTOPERATIVE HEMORRHAGE (prevention
and control)
Tabatabaei, Seyed Vahid
INTERFERON ALFA-2A (therapeutic use)
Sheriff, Dhastagir S.
FATTY LIVER
Tadayon, N.
DENTAL DEVICES, HOME CARE
Shi, Z.
DIET
Taheri, Nima
BONE DENSITY
Shoaib, Muhammad Harris
FLUOROQUINOLONES (pharmacology)
Tahir, Mohammad
OLFACTORY BULB (ultrastructure)
Shoolami, Leila Zahedi
BONE DENSITY
Tai, Javed Majid
Shruthi, D.P.
ANGIOPLASTY, TRANSLUMINAL,
PERCUTANEOUS CORONARY
ORBIT (surgery)
Takahashi, Akira
Siddiqui, Faisal Ghani
ANTINEOPLASTIC AGENTS, PHYTOGENIC
FISSURE IN ANO (surgery)
Tasawar, Zahida
Simaan, Joseph A.
PHARMACOGENETICS
ENTAMOEHA HISTOLYTICA (isolation and
purification)
Simsek, Hakki
Tasci, Sultan
CORONARY ARTERY DISEASE
MULTIPLE SCLEROSIS
Singh, Jaideep
Tasleem, Samiah
PLANTS, MEDICINAL
FLUOROQUINOLONES (pharmacology)
Skaik, Younis Abed Al Wahhab M.
Tayfur, Muhittin
PUBLICATIONS
FOOD MICROBIOLOGY
Sohrab, Negargar
Tehranian, Afsaneh
HEART DEFECTS, CONGENITAL (surgery)
ADNEXAL DISEASES (ultrasonography)
Sojjodi, P.
Tekinsoy, Pinar
OVERWEIGHT (epidemiology)
MULTIPLE SCLEROSIS
107 IMEMR Current Contents
Author Index
Thiruvagounder, Manopriya
Wasfi, O.A.S.
FATTY LIVER
HEPATITIS B SURFACE ANTIGENS (blood)
Todd, Gail
Wazir, Mohammad Aziz
PHYSICIAN-PATIENT RELATIONS
MYXOMA (diagnosis)
Tootoonchi, Hassan
Woodhouse, Nicholas J.Y.
IRON (therapeutic use)
DIABETES MELLITUS, TYPE 2 (genetics)
THYROID NEOPLASMS (pathology)
Torabi, Simin
Yaghini, F.
LIPOMA (diagnosis)
HEPATITIS B VACCINES
Touhami, H.
Yaghoobi, Reza
MYELOPROLIFERATIVE DISORDERS
DERMATOMYCOSES (epidemiology)
Tozun, Mustafa
UROLOGICAL MANIFESTATIONS
DYSMENORRHEA (epidemiology)
Yahyazadeh, S.H.
Tug, A.
Yamout, Karim
PATERNITY
SUBSTANCE-RELATED DISORDERS
(epidemiology)
BREAST NEOPLASMS (etiology)
Tuncer, Mustafa
CORONARY ARTERY DISEASE
Yaseen, Ehab Taha
Tunio, Mutahir Ali
HEARING LOSS, SENSORINEURAL
(epidemiology)
TECHNETIUM TC 99M SESTAMIBI (diagnostic
use)
Yasmin
ul Haq, Anwar
CYCLOOXYGENASE 2 INHIBITORS
(administration and dosage)
VESICOVAGINAL FISTULA (etiology)
Yassa, Narguess
PLANT EXTRACTS (pharmacology)
ul Muqim, Rooh
MYXOMA (diagnosis)
Yazbeck, P.
MUPIROCIN (therapeutic use)
Ullah, Safi
INFECTION CONTROL
Yazdanie, Nazia
ANODONTIA
Umoh, E.
PLANT EXTRACTS (pharmacology)
Yazigi, A.
Unsal, Alaettin
MUPIROCIN (therapeutic use)
UROLOGICAL MANIFESTATIONS
DYSMENORRHEA (epidemiology)
Younis, Nadeem J.
BEHCET SYNDROME
Usmanghani, K.
Younis, Saeed Nahdem
PLANT EXTRACTS (pharmacology)
ECHINOCOCCOSIS, HEPATIC (complications)
Ustadi, Abdulla M.
Youssef, Rasha M.
BEHCET SYNDROME
ANTIHYPERTENSIVE AGENTS (analysis)
Uwakwe, Augustine
Yurttas, Afife
METHEMOGLOBIN
CORONARY ARTERY BYPASS (psychology)
Vaghefikia, Azadeh
Zafar, Wajiha
INFLUENZA A VIRUS, H1N1 SUBTYPE
RH-HR BLOOD-GROUP SYSTEM (genetics)
Ved, P. Narang
Zahid, Bushra
HEARING
MISOPROSTOL (administration and dosage)
Vosoughi, Amir Reza
Zaidi, Zeenat F.
LIPOMA (diagnosis)
PURKINJE CELLS
Vossough, Parvaneh
Zamiri, Nima
BONE DENSITY
URINARY BLADDER NEOPLASMS (genetics)
Wahman, Lobna F.
Zangana, Abdulqadir Maghded
METFORMIN (therapeutic use)
ECHINOCOCCOSIS, HEPATIC (complications)
Walley, T
Zarin, Mohammad
DRUG PRESCRIPTIONS
APPENDECTOMY (methods)
Walley, T.
Zarin, Muhammad
DRUG PRESCRIPTIONS
MEDICATION ERRORS
PHYSICIAN'S PRACTICE PATTERNS
MYXOMA (diagnosis)
Zarrin, Majid
DERMATOMYCOSES (epidemiology)
108 IMEMR Current Contents
Author Index
Zehra, N.
Ziaee, F.
ERYTHROCYTE INDICES
BREAST NEOPLASMS (etiology)
Zein Eldin, Soheir
Ziyarati, L.
HEPATITIS C, CHRONIC
ORAL HEALTH
Zgheib, Nathalie K.
Zoha, S.M.S.
PHARMACOGENETICS
ALKALOIDS (isolation and purification)
Zia ur Rehman
Zubair, Hassan
ESOPHAGEAL NEOPLASMS (pathology)
CELL DIFFERENTIATION (drug effects)
109 Appendix II
List of EMR Journals Indexed in
IMEMR
(by country)
IMEMR Current Contents
EMR Journals List
Journal Title
ISSN
Status
Bahrain (3)
Arab Journal for Food and Nutrition
1608-8352
Active
Bahrain Medical Bulletin
1012-8298
Active
JBMS - Journal of the Bahrain Medical Society
1015-6321
Active
AAMJ - Al-Azhar Assiut Medical Journal
1687-1693
Interrupted
African Journal of Urology
1110-5704
Active
Afro-Arab Liver Journal
1687-224X
Active
Ain-Shams Journal of Forensic Medicine and Clinical Toxicology
1687-1030
Interrupted
Ain-Shams Medical Journal
0002-2144
Active
N/A
Active
Al-Azhar Journal of Dental Science
1110-6751
Interrupted
Al-Azhar Medical Journal
1110-0400
Active
Alexandria Dental Journal
1110-015X
Interrupted
Alexandria Journal of Food Science and Technology
1687-3920
Active
Alexandria Journal of Hepatogastroenterology
2090-1879
Active
Alexandria Journal of Pediatrics
1687-9945
Active
Alexandria Journal of Pharmaceutical Sciences
1110-1792
Interrupted
Alexandria Journal of Veterinary Science
1110-2047
Active
Alexandria Medical Journal [The]
0516-5849
Interrupted
Annals of Pediatric Surgery
1687-4137
Active
Egypt (127)
AJAIC - Alexandria Journal of Anaesthesia and Intensive Care
Applied Endocrinology in Egypt
1110-1776
Active
Arab Journal of Biotechnology
1110-6875
Active
Arab Journal of Gastroenterology
1687-1979
Active
Arab Journal of Laboratory Medicine [The]
1110-1822
Active
ASJOG - Ain-Shams Journal of Obstetrics and Gynecology
1697-2193
Interrupted
ASNJ - Alexandria Scientific Nursing Journal
1687-3858
Active
Assiut Medical Journal
1110-0494
Active
Assiut University Bulletin for Environmental Researches
1110-6107
Active
Benha Medical Journal
1110-208X
Active
Bulletin of Alexandria Faculty of Medicine
1110-0834
Active
N/A
Interrupted
Bulletin of Faculty of Pharmacy - Cairo University
1110-0931
Active
Bulletin of Faculty of Physical Therapy - Cairo University
1110-6611
Active
Bulletin of High Institute of Public Health [The]
1110-0036
Active
Bulletin of Pharmaceutical Sciences - Assiut University
1110-0052
Active
Bulletin of the Faculty of Science - University of Alexandria
0568-9619
Interrupted
Bulletin of Alexandria Thoracic Association
Bulletin of the National Nutrition Institute of the Arab Republic of Egypt
N/A
Active
Bulletin of the National Research Centre
1110-0591
Active
Bulletin of the Ophthalmological Society of Egypt
0078-5342
Interrupted
Childhood and Development Quarterly
1110-8681
Interrupted
113
IMEMR Current Contents
EMR Journals List
ISSN
Status
Clinical Diabetes
Journal Title
0891-8929
Active
EDJ - Egyptian Dental Journal
0070-9484
Active
Egyptian Heart Journal [The]
1110-2608
Active
Egyptian Journal of Anatomy [The]
1110-2144
Interrupted
Egyptian Journal of Biomedical Engineering
1012-5558
Interrupted
Egyptian Journal of Biophysics and Biomedical Engineering
1110-8525
Active
Egyptian Journal of Bronchology [The]
1687-8426
Active
Egyptian Journal of Chemistry
0449-2285
Active
Egyptian Journal of Community Medicine [The]
1110-1865
Active
Egyptian Journal of Dermatology and Andrology
1110-7650
Interrupted
N/A
Active
Egyptian Journal of Diabetes [The]
Egyptian Journal of Food Science
1110-0192
Active
Egyptian Journal of Genetics and Cytology
0046-161X
Interrupted
Egyptian Journal of Histology [The]
1110-0559
Active
Egyptian Journal of Hospital Medicine [The]
1687-2002
Active
Egyptian Journal of Immunology [The]
1110-4902
Active
Egyptian Journal of Medical Human Genetics [The]
1110-8630
Active
Egyptian Journal of Medical Laboratory Sciences
1110-5593
Active
Egyptian Journal of Medical Microbiology
1110-2179
Interrupted
Egyptian Journal of Microbiology
0022-2704
Active
Egyptian Journal of Neonatology [The]
1110-8991
Interrupted
Egyptian Journal of Neurology, Psychiatry and Neurosurgery [The]
1110-1083
Active
Egyptian Journal of Nutrition
1687-1235
Active
Egyptian Journal of Nutrition and Health
1687-7950
Active
Egyptian Journal of Occupational Medicine
1110-1881
Interrupted
Egyptian Journal of Otolaryngology [The]
1012-5574
Active
Egyptian Journal of Paediatrics [The]
1687-1677
Active
Egyptian Journal of Pediatric Allergy and Immunology
1687-1642
Active
Egyptian Journal of Pharmaceutical Sciences
0301-5068
Active
Egyptian Journal of Physiological Sciences
0301-8660
Interrupted
Egyptian Journal of Psychiatry [The]
1110-1105
Interrupted
Egyptian Journal of Schistosomiasis and Infectious and Endemic Diseases
1110-7278
Active
Egyptian Journal of Surgery [The]
1110-1121
Active
Egyptian Journal of Urology
1110-5712
Interrupted
Egyptian Journal of Veterinary Science
1110-0222
Active
Egyptian Medical Journal of the National Research Center
1687-1278
Interrupted
N/A
Interrupted
Egyptian Orthopaedic Journal [The]
1110-1148
Active
Egyptian Pharmaceutical Journal [National Research Center]
1687-4315
Active
N/A
Active
1110-161X
Active
Egyptian Orthodontic Journal
Egyptian Population and Family Planning Review [The]
Egyptian Rheumatology and Rehabilitation
114
IMEMR Current Contents
EMR Journals List
ISSN
Status
Egyptian Science Magazine [The]
Journal Title
1687-3815
Active
EJB - Egyptian Journal of Biochemistry and Molecular Biology [The]
1687-1502
Active
EJENTAS - Egyptian Journal of ENT and Allied Sciences
2090-0740
Active
EMHJ - Eastern Mediterranean Health Journal
1020-3397
Active
Gazette of the Egyptian Paediatric Association [The]
1110-6638
Interrupted
Health Services Journal of the Eastern Mediterrenean Region
1014-9899
Interrupted
JESN - Journal of Egyptian Society of Nephrology [The]
N/A
Active
Journal of Childhood Studies
2090-0619
Active
Journal of Drug Research of Egypt
0085-2406
Active
Journal of Hepatology, Gastroenterology and Infectious Diseases
1110-0796
Interrupted
Journal of Legal Medicine and Forensic Sciences [The]
1110-6468
Active
Journal of the Arab Society for Medical Research
1687-4293
Active
Journal of the Egyptian Medical Association [The]
0013-2411
Interrupted
Journal of the Egyptian National Cancer Institute
1110-0362
Active
N/A
Active
Journal of the Egyptian Public Health Association [The]
Journal of the Egyptian Society of Endocrinology, Metabolism and Diabetes [The]
1110-1245
Active
Journal of the Egyptian Society of Obstetrics and Gynecology [The]
0258-3216
Interrupted
Journal of the Egyptian Society of Parasitology
1110-0583
Active
N/A
Interrupted
Journal of the Egyptian Society of Pharmacology and Experimental Therapeutics [The]
Journal of the Egyptian Society of Toxicology
1110-127X
Active
Journal of the Medical Research Institute - Alexandria University
1110-0133
Interrupted
N/A
Active
JPC - Journal of Pediatric Club [The]
Kasr El Aini Journal of Surgery
0022-9237
Active
Kidney Forum
1369-3050
Interrupted
Mansoura Journal of Pharmaceutical Sciences
1110-1318
Active
Mansoura Medical Journal
1110-211X
Active
N/A
Interrupted
Medical Journal of Ahmed Maher Teaching Hospital [The]
Medical Journal of Cairo University [The]
0045-3803
Active
Medical Journal of Teaching Hospitals and Institutes [The]
1110-2039
Interrupted
Minoufia Medical Journal
1110-2098
Active
MJFCT - Mansoura Journal of Forensic Medicine and Clinical Toxicology
1110-5437
Interrupted
Neonatology
1687-0492
Interrupted
New Egyptian Journal of Medicine [The]
1110-1946
Active
Pan Arab Journal of Orthopaedic and Trauma [The]
1607-4912
Active
Population Researches and Studies
N/A
Active
Population Sciences
N/A
Interrupted
Population Studies
1110-1342
Interrupted
PUJ - Parasitologists United Journal
1687-7942
Active
Scientific Journal of Al-Azhar Medical Faculty [Girls] [The]
1110-2381
Interrupted
Scientific Journal of El-Minia Faculty of Medicine [The]
1110-2446
Active
Scientific Medical Journal
1110-5607
Active
115
IMEMR Current Contents
EMR Journals List
Journal Title
South Valley Medical Journal
ISSN
Status
1110-7529
Active
Suez Canal University Medical Journal
1110-6999
Active
Tanta Medical Journal
1110-1415
Interrupted
Tanta Medical Sciences Journal
1687-5788
Active
Veterinary Medical Journal
1110-1423
Active
Zagazig Journal of Forensic Medicine and Toxicology
1687-160X
Active
Zagazig Journal of Pharmaceutical Sciences
1110-5089
Interrupted
Zagazig Medical Association Journal
1110-2322
Interrupted
Zagazig University Medical Journal
1110-1431
Interrupted
Al-Kindy College Medical Journal
1810-9543
Active
Almustansiriya Journal of Pharmaceutical Sciences
1815-0993
Interrupted
Annals of the College of Medicine - Mosul
0028-1446
Interrupted
N/A
Interrupted
Bulletin of Endemic Disease - Baghdad
0007-4845
Interrupted
DMJ - Dohuk Medical Journal
2071-7326
Active
IMJ - Iraqi Medical Journal
0304-4564
Active
IOJ - Iraqi Orthodontic Journal
1816-0581
Active
IPMJ - Iraqi Postgraduate Medical Journal
1608-8360
Active
Iraqi Army Medical Journal
N/A
Interrupted
Iraqi Journal of Agriculture
1818-6645
Active
N/A
Interrupted
Iraq (30)
Basrah Journal of Surgery
Iraqi Journal of Biotechnology
Iraqi Journal of Community Medicine
1684-5382
Interrupted
Iraqi Journal of Medical Sciences
1681-6579
Interrupted
Iraqi Journal of Microbiology
N/A
Interrupted
Iraqi Journal of Pharmaceutical Sciences
N/A
Interrupted
1814-0823
Interrupted
Journal of Basic Medical Sciences
N/A
Interrupted
Journal of Community Medicine
N/A
Interrupted
Journal of Dohuk University
1812-7568
Interrupted
Journal of Karbala University
Iraqi Journal of Tropical Disease Researches
1813-0410
Interrupted
Journal of the College of Dentistry - Baghdad
N/A
Interrupted
Journal of the Faculty of Medicine - Baghdad
0041-9419
Active
N/A
Interrupted
Kufa Medical Journal
Medical Journal of Basrah University [The]
Medical Journal of Tikrit University [The]
New Iraqi Journal of Medicine [The]
Risafa Medical Journal
0253-0759
Active
N/A
Interrupted
1817-5562
Active
N/A
Interrupted
Scientific Nursing Journal
1812-2388
Active
Zanco Journal of Medical Sciences
1995-5588
Active
116
IMEMR Current Contents
EMR Journals List
Journal Title
ISSN
Status
Islamic Republic of Iran (155)
Acta Medica Iranica
0044-6025
Active
Advances in Cognitive Science
1561-4174
Interrupted
AJMB - Avicenna Journal of Medical Biotechnology
2008-2835
Active
Archives of Iranian Medicine
1029-2977
Active
Armaghane-danesh
1728-6506
Active
ARYA Atherosclerosis Journal
1735-3955
Active
Asian Journal of Sports Medicine
2008-000X
Active
Audiology
1735-1936
Active
Behbood Journal
1735-093X
Active
Bina Journal of Ophthalmology
1026-6399
Active
Cell Journal (Yakhteh)
2228-5806
Active
DARU - Journal of Pharmaceutical Sciences
1560-8115
Active
DENA - Quarterly Journal of Yasuj Faculty of Nursing and Midwifery
1735-8450
Active
Dental Journal - Shaheed Beheshti University of Medical Sciences
1735-7683
Active
DRJ - Dental Research Journal
1735-3327
Active
Endovascular Journal
2008-1812
Active
Feyz - Journal of Kashan University of Medical Sciences
1029-7855
Active
Gastroenterology and Hepatology from Bed to Bench
2010-2258
Active
Genetics in the 3rd Millennium
1728-6182
Active
Govaresh
1560-7186
Active
HAKIM Research Journal
1561-252X
Active
HAYAT - Journal of Faculty of Nursing and Midwifery [The]
1735-2215
Active
Health Information Management
1735-7853
Active
Hepatitis Monthly
1735-143X
Active
Homa-ye-Salamat
2008-2002
Active
Hormozgan Medical Journal
1735-2223
Active
IBJ - Iranian Biomedical Journal
1028-852X
Active
IEJ - Iranian Endodontic Journal
1735-7497
Active
IHJ - Iranian Heart Journal
1735-7306
Active
IJB - Iranian Journal of Biotechnology
1728-3043
Active
IJBC - Iranian Journal of Blood and Cancer
2008-4595
Active
IJCN - Iranian Journal of Child Neurology
1735-4668
Active
IJEM - Iranian Journal of Endocrinology and Metabolism
1683-4844
Active
IJFS - International Journal of Fertility and Sterility
2008-076X
Active
IJHOSCR - International Journal of Hematology-Oncology and Stem Cell Research
2008-2207
Active
IJI - Iranian Journal of Immunology
1735-1383
Active
IJKD - Iranian Journal of Kidney Diseases
1735-8582
Active
IJME - Iranian Journal of Medical Education
1608-9359
Active
IJMS - Iranian Journal of Medical Sciences
0253-0716
Active
IJO - Iranian Journal of Orthodontics
1735-5087
Active
117
IMEMR Current Contents
EMR Journals List
Journal Title
ISSN
Status
1735-0328
Interrupted
IJRM - Iranian Journal of Reproductive Medicine
1680-6433
Active
International Journal of Endocrinology and Metabolism
1726-913X
Active
International Journal of Environmental Research
1735-6865
Active
International Journal of Environmental Science and Technology
1735-1472
Active
International Journal of Occupational and Environmental Medicine
2008-6520
Active
International Journal of Organ Transplantation Medicine
2008-6490
Active
INTJVR - International Journal of Veterinary Research
2008-2533
Ative
IJPR - Iranian Journal of Pharmaceutical Research
Iran Journal of Nursing
2008-5923
Active
Iranian Cardiovascular Research Journal
1735-885X
Active
Iranian Journal of Allergy, Asthma and Immunology
1735-1502
Active
Iranian Journal of Arthropod-Borne Diseases
1735-7179
Active
Iranian Journal of Basic Medical Sciences
2008-3866
Active
Iranian Journal of Cancer Prevention
2008-2398
Active
Iranian Journal of Clinical Infectious Diseases
1735-5109
Active
Iranian Journal of Dermatology
0021-082X
Active
Iranian Journal of Diabetes and Lipid Disorders
1726-7544
Active
Iranian Journal of Diabetes and Obesity
2008-6792
Active
Iranian Journal of Environmental Health Science and Engineering
1735-1979
Active
Iranian Journal of Epidemiology
1735-7489
Active
Iranian Journal of Health and Environment
2008-2029
Active
Iranian Journal of Medical Microbiology
1735-8612
Active
Iranian Journal of Medical Physics
1735-160X
Active
Iranian Journal of Nuclear Medicine
1681-2824
Active
Iranian Journal of Nursing and Midwifery Research [IJNMR]
1735-9066
Active
Iranian Journal of Nutrition Sciences and Food Technology
1735-7756
Active
Iranian Journal of Obstetric, Gynecology and Infertility [The]
1680-2993
Active
Iranian Journal of Ophthalmology
1735-4153
Active
Iranian Journal of Otorhinolaryngology
1560-1293
Active
Iranian Journal of Parasitology
1735-7020
Active
Iranian Journal of Pediatrics
2008-2142
Active
Iranian Journal of Psychiatry
1735-4587
Active
Iranian Journal of Psychiatry and Behavioral Sciences
1735-8639
Active
Iranian Journal of Psychiatry and Clinical Psychology (ANDEESHEH VA RAFTAR)
4315-1735
Active
Iranian Journal of Public Health
0304-4556
Active
Iranian Journal of Radiation Research
1728-4554
Active
Iranian Journal of Radiology
1735-1065
Active
Iranian Journal of Veterinary Research
1728-1997
Active
Iranian Rehabilitation Journal
1735-3602
Active
JBUMS - Journal of Babol University of Medical Sciences
1561-4107
Active
JDT - Journal of Dentistry Tehran University of Medical Sciences
1735-2150
Active
118
IMEMR Current Contents
EMR Journals List
Journal Title
ISSN
Status
1728-1962
Interrupted
Journal of Arak University of Medical Sciences - Rahavard Danesh
1735-5338
Active
Journal of Dental Medicine - Tehran University of Medical Sciences
1024-641X
Active
Journal of Dental Research, Dental Clinics, Dental Prospects
2008-210X
Active
Journal of Dentistry - Shiraz University of Medical Sciences
1728-3426
Active
Journal of Environmental Studies
1025-8620
Active
Journal of Faculty of Nursing and Midwifery Quarterly- Shaheed Beheshti University of
Medical Sciences
1605-8941
Active
Journal of Fundamentals of Mental Health [The]
1028-6918
Active
Journal of Gorgan University of Medical Sciences
1562-4765
Active
Journal of Guilan University of Medical Sciences
2008-4048
Active
Journal of Health Administration
2008-1200
Active
Journal of Hygiene and Health
1735-2363
Active
Journal of Injury and Violence Research
2008-2053
Active
Journal of Iranian Anatomical Sciences
1728-6158
Active
Journal of Isfahan Dental School
1735-255X
Active
JMR - Journal of Medical Research
Journal of Isfahan Medical School
1027-7595
Active
Journal of Islamic Dental Association of Iran [The] - JIDA
1024-6428
Active
Journal of Jahrom University of Medical Sciences
1735-5168
Active
Journal of Kerman University of Medical Sciences
1023-9510
Active
Journal of Mashhad Dental School
1560-9286
Active
Journal of Mazandaran University of Medical Sciences
1735-9260
Active
Journal of Medical Council of Islamic Republic of Iran
1562-1073
Active
Journal of Medical Education
1735-3998
Active
Journal of Medical Science - Islamic Azad University of Mashhad
1735-7594
Active
Journal of Medicinal Plants
1684-0240
Active
Journal of Ophthalmic and Vision Research
2008-2010
Active
N/A
Active
Journal of Periodontology and Implant Dentistry
Journal of Qazvin University of Medical Sciences [The]
1561-3666
Active
Journal of Rafsanjan University of Medical Sciences
1735-3165
Active
Journal of Rehabilitation
1607-2960
Active
Journal of Reproduction and Infertility
1726-7536
Active
Journal of Research in Behavioural Sciences
1735-2029
Active
Journal of Research in Health Sciences [JRHS]
1682-2765
Active
Journal of Research in Medical Sciences
1735-5311
Active
Journal of Sabzevar School of Medical Sciences
1606-7487
Active
Journal of School of Public Health and Institute of Public Health Research
1735-7586
Active
Journal of Shaheed Sadoughi University of Medical Sciences and Health Services
1562-272X
Active
Journal of Shahrekord University of Medical Sciences
1735-1448
Active
Journal of Tehran University Heart Center [The]
1735-8620
Active
Journal of Veterinary Research
2010-2525
Active
Journal of Zahedan University of Medical Sciences and Health Services
1735-076X
Active
119
IMEMR Current Contents
EMR Journals List
Journal Title
Journal of Zanjan University of Medical Sciences and Health Services
ISSN
Status
1606-9366
Active
JRMS - Journal of Research in Medical Sciences
1735-1995
Active
JRRS - Journal of Research in Rehabilitation Sciences
1735-7519
Active
Jundishapur Journal of Microbiology [JJM]
2008-3645
Active
KOOMESH - Journal of the Semnan University of Medical Sciences
1608-7046
Active
Medical Journal of Mashad University of Medical Sciences
1735-4013
Active
Medical Journal of Tabriz University of Medical Sciences and Health Services
1608-5671
Active
Medical Journal of the Islamic Republic of Iran
1016-1430
Interrupted
Medical Sciences Journal of Islamic Azad University
1023-5922
Active
MEJC - Middle East Journal of Cancer
2008-6709
Active
Middle East Journal of Digestive Diseases
2008-5230
Active
Modares Journal of Medical Sciences
1562-9554
Active
Nursing and Midwifery Research
1753-5001
Active
Ofogh-E-Danesh
1735-1855
Active
Payesh - Health Monitor
1680-7626
Active
Pejouhandeh: Bimonthly Research Journal
1735-1022
Active
Qom University of Medical Sciences Journal
1735-7799
Active
Quarterly Journal of Medical Ethics
2008-4374
Active
N/A
Active
Quarterly Journal of Relief and Rescue
4544-2008
Active
Salmand - Iranian Journal of Aging
1735-806X
Active
Quarterly Journal of Medical Law
Scientific and Research Journal of Army University of Medical Sciences - J.A.U.M.S.
1727-1789
Active
Scientific Journal of Forensic Medicine
1027-1457
Active
Scientific Journal of Iranian Blood Transfusion Organization Research Center [The]
1027-9520
Active
Scientific Journal of Kurdistan University of Medical Sciences
1560-652X
Active
Scientific Medical Journal - Biomomthly Medical Research Journal Ahvaz Jundishapur
University of Medical Sciences [The]
1026-8960
Active
Social Welfare Quarterly
1735-8191
Active
Strides in Development of Medical Education
1735-4242
Active
Tanaffos
1735-0344
Active
Tehran University Medical Journal [TUMJ]
1683-1764
Active
Toloo-e-Behdasht
1728-5127
Active
Urology Journal
1735-1308
Active
Yafteh Journal
1563-0773
Active
Jordan (9)
Arab Journal of Psychiatry [The]
1016-8923
Active
Dirasat
1026-3772
Active
Jordan Journal of Pharmaceutical Sciences
1995-7157
Active
Jordan Medical Journal
0446-9283
Active
Journal of the Royal Medical Services
2078-8703
Active
Medical Journal of Islamic World Academy of Sciences
1016-3360
Active
N/A
Interrupted
Pan Arab Medical Journal
120
IMEMR Current Contents
EMR Journals List
ISSN
Status
Population Bulletin of ESCWA
Journal Title
0258-1914
Interrupted
Smile Dental Journal
2072-473X
Active
Bulletin of the Kuwait Institute for Medical Specialization
N/A
Active
Food and Nutrition Bulletin
N/A
Active
GJO - Gulf Journal of Oncology [The]
2078-2101
Active
KMJ - Kuwait Medical Journal
0023-5776
Active
N/A
Active
1011-7571
Active
1683-8068
Active
Kuwait (6)
Medical Arabization
Medical Principles and Practice
Lebanon (9)
ACES - Actualites Cliniques et Scientifiques
AJU - Arab Journal of Urology
N/A
Active
Arab Dental Journal
N/A
Interrupted
1810-9632
Active
Journal of the Arab Neonatology Forum
1812-1756
Interrupted
Lebanese Science Journal
1561-3410
Active
LMJ - Lebanese Medical Journal
0023-9852
Active
Middle East Journal of Anesthesiology
0544-0440
Active
Middle East Journal of Family Medicine
N/A
Active
N/A
Active
JLDA - Journal of the Lebanese Dental Association
Libyan Arab Jamahiriya (6)
DMJ - Derna Medical Journal
Garyounis Medical Journal
0254-7198
Interrupted
JMJ - Jamahiriya Medical Journal
N/A
Active
Libyan Journal of Infectious Diseases [The]
N/A
Active
LJM - Libyan Journal of Medicine
1819-6357
Active
N/A
Interrupted
Bulletin Epidemiologique
0851-8238
Interrupted
Journal du Practicien
1113-5667
Interrupted
Maroc Medical
0025-4053
Active
N/A
Active
Tabib Attifil Alarabi
Morocco (6)
Revue Marocaine de Chirurgie Orthopedique et Traumatologique
Revue Marocaine de Medecine et Sante
Revue Marocaine des Maladies de L'Enfant
0251-0758
Active
N/A
Interrupted
Oman (3)
Oman Journal of Ophthalmology
0974-620X
Active
Oman Medical Journal
1999-768X
Active
SQUMJ - Sultan Qaboos University Medical Journal
2075-051X
Active
Anaesthesia, Pain and Intensive Care
1607-8322
Active
Annals Abbassi Shaheed Hospital and Karachi Medical and Dental College
1563-3241
Active
N/A
Interrupted
Pakistan (71)
Annals of Jinnah Postgraduate Medical Centre - Karachi
121
IMEMR Current Contents
EMR Journals List
Journal Title
Annals of King Edward Medical College
ISSN
Status
1684-6680
Active
APMC -Annals of Punjab Medical College
1024-8919
Active
Bahria Journal of Professional Psychology
1816-0840
Active
Biomedica
1992-4852
Active
Challenge - Quarterly [The]
0528-7944
Interrupted
Community Medicine
0301-7265
Interrupted
Diabetes Digest
1369-7501
Active
GJMS - Gomal Journal of Medical Sciences
1819-7973
Active
Hamdard Medicus
0250-7188
Active
Infectious Diseases Journal of Pakistan
1027-0299
Active
International Journal of Pathology
1810-0155
Active
Isra Medical Journal
2073-8285
Active
JAMC - Journal of Ayub Medical College - Abbotabad - Pakistan
1025-9589
Active
JCPSP - Journal of the College of Physicians and Surgeons Pakistan
1022-386X
Active
JDUHS - Journal of the Dow University of Health Sciences
1995-2198
Active
JKCD - Journal of Khyber College of Dentistry
2220-2633
Active
JLUMHS - Journal of the Liaquat University of Medical Health Sciences
1729-0341
Active
N/A
Interrupted
JOPDAK - Journal of the Pakistan Dental Association Karachi
Journal of Basic and Applied Sciences
1814-8085
Active
Journal of Medical Sciences
1682-4474
Active
Journal of Medical Sciences
1997-3438
Active
Journal of Nephrology Urology and Transplantation
N/A
Interrupted
Journal of Surgery [The]
1681-4517
Interrupted
JPAD - Journal of Pakistan Association of Dermatologists
1560-9014
Active
JPDA - Journal of the Pakistan Dental Association
1680-2292
Active
JPIMS - Journal of Pakistan Institute of Medical Sciences
1683-6928
Interrupted
JPMA - Journal of Pakistan Medical Association
0030-9982
Active
JPMI - Journal of Postgraduate Medical Institute
1013-5472
Active
JPPS - Journal of Pakistan Psychiatric Society
1726-8710
Active
JSP - Journal of Surgery Pakistan International
1817-0242
Active
KMJ - KUST Medical Journal
2072-7763
Active
N/A
Interrupted
Medical Channel
1681-5491
Active
Medical Forum Monthly
1029-385X
Active
Medical Spectrum [The]
0254-8534
Interrupted
Medicine Today
1813-9876
Active
Mother and Child
0379-2617
Interrupted
Lahore Journal of Public Health
PAFMJ - Pakistan Armed Forces Medical Journal
0030-9648
Active
Pakistan Heart Journal
0048-2706
Active
Pakistan Journal of Biochemistry
0300-8185
Interrupted
N/A
Active
Pakistan Journal of Chest Medicine
122
IMEMR Current Contents
EMR Journals List
Journal Title
Pakistan Journal of Clinical Psychology
ISSN
Status
1019-438X
Active
Pakistan Journal of Community Medicine [The]
N/A
Interrupted
Pakistan Journal of Health
N/A
Interrupted
Pakistan Journal of Medical and Health Sciences
Pakistan Journal of Medical Ethics
Pakistan Journal of Medical Sciences
1996-7195
Active
N/A
Active
1682-024X
Active
Pakistan Journal of Neurology
N/A
Interrupted
Pakistan Journal of Obstetrics and Gynaecology
N/A
Active
Pakistan Journal of Ophthalmology
0886-3067
Interrupted
Pakistan Journal of Orthodontics, Pediatric and Community Dentistry
1608-134X
Interrupted
Pakistan Journal of Otolaryngology - Head and Neck Surgery
0257-4985
Active
Pakistan Journal of Pathology
1024-6193
Active
Pakistan Journal of Pharmaceutical Sciences
1011-601X
Active
Pakistan Journal of Pharmacology
0255-7088
Active
Pakistan Journal of Physiology
1819-270X
Active
Pakistan Journal of Psychology
0030-9869
Active
Pakistan Journal of Scientific and Industrial Research
0030-9885
Active
Pakistan Medical Journal
0031-000X
Interrupted
Pakistan Ophthalmology
0259-3661
Interrupted
Pakistan Oral and Dental Journal
1012-8700
Active
Pakistan Paediatric Journal
0304-4904
Active
PJC - Pakistan Journal of Cardiology
1016-1244
Active
PJMR - Pakistan Journal of Medical Research
0030-9842
Active
PJS - Pakistan Journal of Surgery
0258-8552
Active
Proceedings
N/A
Active
Professional Medical Journal - Quarterly [The]
1024-8919
Active
RMJ - Rawal Medical Journal
0303-5212
Active
Palestine (3)
Al-Quds Medical Journal
N/A
Interrupted
1815-2635
Active
N/A
Active
N/A
Interrupted
Heart Views
1995-705X
Active
JEMTAC - Journal of Emergency Medicine, Trauma and Acute Care
1999-7086
Active
Qatar Medical Journal
0253-8253
Active
Annals of Alquds Medicine
PMJ - Palestinian Medical Journal
Qatar (4)
Gulf Journal of Dermatology and Venereology [The]
Saudi Arabia (29)
Annals of Saudi Medicine
0256-4947
Active
Annals of Thoracic Medicine
1817-1737
Active
Hematology, Oncology and Stem Cell Therapy
1658-3876
Active
International Journal of Diabetes Mellitus
1877-5934
Active
123
IMEMR Current Contents
EMR Journals List
Journal Title
International Journal of Health Sciences
Joint Centre for Research in Prosthetics and Orthotics [The]
ISSN
Status
1658-3639
Active
N/A
Interrupted
Journal of Family and Community Medicine
1319-1683
Active
Journal of Infection and Public Health
1876-0341
Active
Journal of King Abdulaziz University - Medical Sciences
1319-1004
Interrupted
Journal of Taibah University Medical Sciences
1658-3612
Active
Journal of the Saudi Heart Association
1016-7315
Active
MEAJO - Middle East African Journal of Ophthalmology
0974-9233
Active
Neurosciences
1319-6138
Active
Pan Arab Journal of Neurosurgery
1319-6995
Active
N/A
Interrupted
Research Centre Bulletin
1019-5335
Interrupted
Saudi Epidemiology Bulletin
1319-3965
Active
Saudi Heart Journal
1018-077X
Interrupted
Saudi Journal of Disability and Rehabilitation
1319-6499
Active
Saudi Journal of Gastroenterology [The]
1319-3767
Active
Saudi Journal of Oto-Rhino-Laryngology Head and Neck Surgery [The]
1319-8491
Interrupted
Saudi Journal of Sports Medicine [The]
1319-6308
Interrupted
Saudi Medical Journal
0379-5284
Active
SDJ - Saudi Dental Journal [The]
1013-9052
Active
SGH Medical Journal
1658-2489
Active
SJA - Saudi Journal of Anaesthesia
1658-354X
Active
SJO - Saudi Journal of Ophthalmology
1319-4534
Active
SPJ - Saudi Pharmaceutical Journal
1319-0164
Active
Urology Annals
0974-7796
Active
1810-5386
Active
JMJ - Juba Medical Journal
N/A
Interrupted
Khartoum Pharmacy Journal
N/A
Interrupted
Omdurman Journal of Pharmaceutical Sciences
N/A
Active
SJPH - Sudanese Journal of Public Health
1990-7567
Active
Sudan Journal of Medical Sciences
1858-5051
Active
Sudan Medical Journal
0491-4481
Interrupted
Sudan Medical Monitor
1858-5000
Active
Sudanese Journal of Dermatology
1815-3941
Active
1683-0369
Active
Arabic Journal of Forensic Medicine and Criminal Science
N/A
Active
Damascus University Journal for Health Sciences
N/A
Active
JABHS - Journal of the Arab Board of Health Specializations
1561-0217
Active
JISHIM - Journal of the International Society for the History of Islamic Medicine
1303-667X
Active
Rehabilitation International
Sudan (9)
Gezira Journal of Health Sciences
Syrian Arab Republic (9)
Arab Journal of Pharmaceutical Sciences
124
IMEMR Current Contents
EMR Journals List
Journal Title
Journal of Clinical Laboratory [The]
Journal of the Arab Board of Medical Specializations
ISSN
Status
N/A
Active
1561-0217
Active
Journal of the Arab Dentist
N/A
Interrupted
Research Journal of Aleppo University - Medical Sciences Series
N/A
Active
Tunisia (9)
Archives de l'Institut Pasteur de Tunis
0020-2509
Active
Cahiers Medicaux de Tunisie
0300-5291
Interrupted
N/A
Interrupted
IDEES - Revue de Perfectionnement Medical et Paramedical
Maghreb Medical
0330-258X
Active
Revue Maghrebine de Pediatrie [La]
0330-7611
Active
N/A
Active
1737-8958
Active
Revue Maghrebine d'Endocrinologie - Diabete et de Reproduction [La]
Revue Tunisienne d'Infectiologie
SST - Sante et Securite au Travail
Tunisie Medicale [La]
N/A
Active
0041-4131
Active
United Arab Emirates (4)
EMJ - Emirates Medical Journal
0250-6882
Active
International Journal of Diabetes and Metabolism
1606-7754
Active
IRCMJ - Iranian Red Crescent Medical Journal
1561-4395
Active
JMS - Journal of Medical Sciences
1996-3262
Active
N/A
Active
N/A
Interrupted
Yemen (7)
Journal of Tropical Nephro-Urology
Sana'a University Journal of Medical Sciences
University of Aden Journal of Natural and Applied Sciences
1606-8947
Active
Yemeni Journal for Medical Sciences [The]
N/A
Interrupted
YHMRJ - Yemeni Health and Medical Research Journal
N/A
Active
YJMHR - Yemeni Journal of Medical and Health Research
N/A
Interrupted
YMJ - Yemen Medical Journal
N/A
Interrupted
Last update June 2011
125
Appendix III
List of EMR Journals Indexed in
IMEMR
(by title)
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
1
AAMJ - Al-Azhar Assiut Medical Journal
1687-1693
Interrupted
2
ACES - Actualites Cliniques et Scientifiques
1683-8068
Active
3
Acta Medica Iranica
0044-6025
Active
4
Advances in Cognitive Science
1561-4174
Interrupted
5
African Journal of Urology
1110-5704
Active
6
Afro-Arab Liver Journal
1687-224X
Active
7
Ain-Shams Journal of Forensic Medicine and Clinical Toxicology
1687-1030
Interrupted
8
Ain-Shams Medical Journal
0002-2144
Active
9
AJAIC - Alexandria Journal of Anaesthesia and Intensive Care
N/A
Active
10
AJMB - Avicenna Journal of Medical Biotechnology
2008-2835
Active
11
AJU - Arab Journal of Urology
N/A
Active
12
Al-Azhar Journal of Dental Science
1110-6751
Interrupted
13
Al-Azhar Medical Journal
1110-0400
Active
14
Alexandria Dental Journal
1110-015X
Interrupted
15
Alexandria Journal of Food Science and Technology
1687-3920
Active
16
Alexandria Journal of Hepatogastroenterology
2090-1879
Active
17
Alexandria Journal of Pediatrics
1687-9945
Active
18
Alexandria Journal of Pharmaceutical Sciences
1110-1792
Interrupted
19
Alexandria Journal of Veterinary Science
1110-2047
Active
20
Alexandria Medical Journal [The]
0516-5849
Interrupted
21
Al-Kindy College Medical Journal
1810-9543
Active
22
Almustansiriya Journal of Pharmaceutical Sciences
1815-0993
Interrupted
23
Al-Quds Medical Journal
N/A
Interrupted
24
Anaesthesia, Pain and Intensive Care
1607-8322
Active
25
Annals Abbassi Shaheed Hospital and Karachi Medical and Dental
College
1563-3241
Active
26
Annals of Alquds Medicine
1815-2635
Active
27
Annals of Jinnah Postgraduate Medical Centre - Karachi
N/A
Interrupted
28
Annals of King Edward Medical College
1684-6680
Active
29
Annals of Pediatric Surgery
1687-4137
Active
30
Annals of Saudi Medicine
0256-4947
Active
31
Annals of the College of Medicine - Mosul
0028-1446
Interrupted
32
Annals of Thoracic Medicine
1817-1737
Active
33
APMC -Annals of Punjab Medical College
1024-8919
Active
34
Applied Endocrinology in Egypt
1110-1776
Active
35
Arab Dental Journal
N/A
Interrupted
129
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
36
Arab Journal for Food and Nutrition
1608-8352
Active
37
Arab Journal of Biotechnology
1110-6875
Active
38
Arab Journal of Gastroenterology
1687-1979
Active
39
Arab Journal of Laboratory Medicine [The]
1110-1822
Active
40
Arab Journal of Pharmaceutical Sciences
1683-0369
Active
41
Arab Journal of Psychiatry [The]
1016-8923
Active
42
Arabic Journal of Forensic Medicine and Criminal Science
N/A
Active
43
Archives de l'Institut Pasteur de Tunis
0020-2509
Active
44
Archives of Iranian Medicine
1029-2977
Active
45
Armaghane-danesh
1728-6506
Active
46
ARYA Atherosclerosis Journal
1735-3955
Active
47
Asian Journal of Sports Medicine
2008-000X
Active
48
ASJOG - Ain-Shams Journal of Obstetrics and Gynecology
1697-2193
Interrupted
49
ASNJ - Alexandria Scientific Nursing Journal
1687-3858
Active
50
Assiut Medical Journal
1110-0494
Active
51
Assiut University Bulletin for Environmental Researches
1110-6107
Active
52
Audiology
1735-1936
Active
53
Bahrain Medical Bulletin
1012-8298
Active
54
Bahria Journal of Professional Psychology
1816-0840
Active
55
Basrah Journal of Surgery
N/A
Interrupted
56
Behbood Journal
1735-093X
Active
57
Benha Medical Journal
1110-208X
Active
58
Bina Journal of Ophthalmology
1026-6399
Active
59
Biomedica
1992-4852
Active
60
Bulletin Epidemiologique
0851-8238
Interrupted
61
Bulletin of Alexandria Faculty of Medicine
1110-0834
Active
62
Bulletin of Alexandria Thoracic Association
N/A
Interrupted
63
Bulletin of Endemic Disease - Baghdad
0007-4845
Interrupted
64
Bulletin of Faculty of Pharmacy - Cairo University
1110-0931
Active
65
Bulletin of Faculty of Physical Therapy - Cairo University
1110-6611
Active
66
Bulletin of High Institute of Public Health [The]
1110-0036
Active
67
Bulletin of Pharmaceutical Sciences - Assiut University
1110-0052
Active
68
Bulletin of the Faculty of Science - University of Alexandria
0568-9619
Interrupted
69
Bulletin of the Kuwait Institute for Medical Specialization
N/A
Active
70
Bulletin of the National Nutrition Institute of the Arab Republic of
Egypt
N/A
Active
130
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
71
Bulletin of the National Research Centre
1110-0591
Active
72
Bulletin of the Ophthalmological Society of Egypt
0078-5342
Interrupted
73
Cahiers Medicaux de Tunisie
0300-5291
Interrupted
74
Cell Journal (Yakhteh)
2228-5806
Active
75
Challenge - Quarterly [The]
0528-7944
Interrupted
76
Childhood and Development Quarterly
1110-8681
Interrupted
77
Clinical Diabetes
0891-8929
Active
78
Community Medicine
0301-7265
Interrupted
79
Damascus University Journal for Health Sciences
N/A
Active
80
DARU - Journal of Pharmaceutical Sciences
1560-8115
Active
81
DENA - Quarterly Journal of Yasuj Faculty of Nursing and
Midwifery
1735-8450
Active
82
Dental Journal - Shaheed Beheshti University of Medical Sciences
1735-7683
Active
83
Diabetes Digest
1369-7501
Active
84
Dirasat
1026-3772
Active
85
DMJ - Derna Medical Journal
N/A
Active
86
DMJ - Dohuk Medical Journal
2071-7326
Active
87
DRJ - Dental Research Journal
1735-3327
Active
88
EDJ - Egyptian Dental Journal
0070-9484
Active
89
Egyptian Heart Journal [The]
1110-2608
Active
90
Egyptian Journal of Anatomy [The]
1110-2144
Interrupted
91
Egyptian Journal of Biomedical Engineering
1012-5558
Interrupted
92
Egyptian Journal of Biophysics and Biomedical Engineering
1110-8525
Active
93
Egyptian Journal of Bronchology [The]
1687-8426
Active
94
Egyptian Journal of Chemistry
0449-2285
Active
95
Egyptian Journal of Community Medicine [The]
1110-1865
Active
96
Egyptian Journal of Dermatology and Andrology
1110-7650
Interrupted
97
Egyptian Journal of Diabetes [The]
N/A
Active
98
Egyptian Journal of Food Science
1110-0192
Active
99
Egyptian Journal of Genetics and Cytology
0046-161X
Interrupted
100
Egyptian Journal of Histology [The]
1110-0559
Active
101
Egyptian Journal of Hospital Medicine [The]
1687-2002
Active
102
Egyptian Journal of Immunology [The]
1110-4902
Active
103
Egyptian Journal of Medical Human Genetics [The]
1110-8630
Active
104
Egyptian Journal of Medical Laboratory Sciences
1110-5593
Active
105
Egyptian Journal of Medical Microbiology
1110-2179
Interrupted
131
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
106
Egyptian Journal of Microbiology
0022-2704
Active
107
Egyptian Journal of Neonatology [The]
1110-8991
Interrupted
108
Egyptian Journal of Neurology, Psychiatry and Neurosurgery [The]
1110-1083
Active
109
Egyptian Journal of Nutrition
1687-1235
Active
110
Egyptian Journal of Nutrition and Health
1687-7950
Active
111
Egyptian Journal of Occupational Medicine
1110-1881
Interrupted
112
Egyptian Journal of Otolaryngology [The]
1012-5574
Active
113
Egyptian Journal of Paediatrics [The]
1687-1677
Active
114
Egyptian Journal of Pediatric Allergy and Immunology
1687-1642
Active
115
Egyptian Journal of Pharmaceutical Sciences
0301-5068
Active
116
Egyptian Journal of Physiological Sciences
0301-8660
Interrupted
117
Egyptian Journal of Psychiatry [The]
1110-1105
Interrupted
118
Egyptian Journal of Schistosomiasis and Infectious and Endemic
Diseases
1110-7278
Active
119
Egyptian Journal of Surgery [The]
1110-1121
Active
120
Egyptian Journal of Urology
1110-5712
Interrupted
121
Egyptian Journal of Veterinary Science
1110-0222
Active
122
Egyptian Medical Journal of the National Research Center
1687-1278
Interrupted
123
Egyptian Orthodontic Journal
N/A
Interrupted
124
Egyptian Orthopaedic Journal [The]
1110-1148
Active
125
Egyptian Pharmaceutical Journal [National Research Center]
1687-4315
Active
126
Egyptian Population and Family Planning Review [The]
N/A
Active
127
Egyptian Rheumatology and Rehabilitation
1110-161X
Active
128
Egyptian Science Magazine [The]
1687-3815
Active
129
EJB - Egyptian Journal of Biochemistry and Molecular Biology
[The]
1687-1502
Active
130
EJENTAS - Egyptian Journal of ENT and Allied Sciences
2090-0740
Active
131
EMHJ - Eastern Mediterranean Health Journal
1020-3397
Active
132
EMJ - Emirates Medical Journal
0250-6882
Active
133
Endovascular Journal
2008-1812
Active
134
Feyz - Journal of Kashan University of Medical Sciences
1029-7855
Active
135
Food and Nutrition Bulletin
N/A
Active
136
Garyounis Medical Journal
0254-7198
Interrupted
137
Gastroenterology and Hepatology from Bed to Bench
2010-2258
Active
138
Gazette of the Egyptian Paediatric Association [The]
1110-6638
Interrupted
139
Genetics in the 3rd Millennium
1728-6182
Active
140
Gezira Journal of Health Sciences
1810-5386
Active
132
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
141
GJMS – Gomal Journal of Medical Sciences
1819-7973
Active
142
GJO - Gulf Journal of Oncology [The]
2078-2101
Active
143
Govaresh
1560-7186
Active
144
Gulf Journal of Dermatology and Venereology [The]
N/A
Interrupted
145
HAKIM Research Journal
1561-252X
Active
146
Hamdard Medicus
0250-7188
Active
147
HAYAT - Journal of Faculty of Nursing and Midwifery [The]
1735-2215
Active
148
Health Information Management
1735-7853
Active
149
Health Services Journal of the Eastern Mediterrenean Region
1014-9899
Interrupted
150
Heart Views
1995-705X
Active
151
Hematology, Oncology and Stem Cell Therapy
1658-3876
Active
152
Hepatitis Monthly
1735-143X
Active
153
Homa-ye-Salamat
2008-2002
Active
154
Hormozgan Medical Journal
1735-2223
Active
155
IBJ - Iranian Biomedical Journal
1028-852X
Active
156
IDEES - Revue de Perfectionnement Medical et Paramedical
N/A
Interrupted
157
IEJ - Iranian Endodontic Journal
1735-7497
Active
158
IHJ - Iranian Heart Journal
1735-7306
Active
159
IJB - Iranian Journal of Biotechnology
1728-3043
Active
160
IJBC - Iranian Journal of Blood and Cancer
2008-4595
Active
161
IJCN - Iranian Journal of Child Neurology
1735-4668
Active
162
IJEM - Iranian Journal of Endocrinology and Metabolism
1683-4844
Active
163
IJFS - International Journal of Fertility and Sterility
2008-076X
Active
164
IJHOSCR - International Journal of Hematology-Oncology and
Stem Cell Research
2008-2207
Active
165
IJI - Iranian Journal of Immunology
1735-1383
Active
166
IJKD - Iranian Journal of Kidney Diseases
1735-8582
Active
167
IJME - Iranian Journal of Medical Education
1608-9359
Active
168
IJMS - Iranian Journal of Medical Sciences
0253-0716
Active
169
IJO - Iranian Journal of Orthodontics
1735-5087
Active
170
IJPR - Iranian Journal of Pharmaceutical Research
1735-0328
Interrupted
171
IJRM - Iranian Journal of Reproductive Medicine
1680-6433
Active
172
IMJ - Iraqi Medical Journal
0304-4564
Active
173
Infectious Diseases Journal of Pakistan
1027-0299
Active
174
International Journal of Diabetes and Metabolism
1606-7754
Active
175
International Journal of Diabetes Mellitus
1877-5934
Active
133
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
176
International Journal of Endocrinology and Metabolism
1726-913X
Active
177
International Journal of Environmental Research
1735-6865
Active
178
International Journal of Environmental Science and Technology
1735-1472
Active
179
International Journal of Health Sciences
1658-3639
Active
180
International Journal of Occupational and Environmental Medicine
2008-6520
Active
181
International Journal of Organ Transplantation Medicine
2008-6490
Active
182
International Journal of Pathology
1810-0155
Active
183
INTJVR - International Journal of Veterinary Research
2008-2533
Ative
184
IOJ - Iraqi Orthodontic Journal
1816-0581
Active
185
IPMJ - Iraqi Postgraduate Medical Journal
1608-8360
Active
186
Iran Journal of Nursing
2008-5923
Active
187
Iranian Cardiovascular Research Journal
1735-885X
Active
188
Iranian Journal of Allergy, Asthma and Immunology
1735-1502
Active
189
Iranian Journal of Arthropod-Borne Diseases
1735-7179
Active
190
Iranian Journal of Basic Medical Sciences
2008-3866
Active
191
Iranian Journal of Cancer Prevention
2008-2398
Active
192
Iranian Journal of Clinical Infectious Diseases
1735-5109
Active
193
Iranian Journal of Dermatology
0021-082X
Active
194
Iranian Journal of Diabetes and Lipid Disorders
1726-7544
Active
195
Iranian Journal of Diabetes and Obesity
2008-6792
Active
196
Iranian Journal of Environmental Health Science and Engineering
1735-1979
Active
197
Iranian Journal of Epidemiology
1735-7489
Active
198
Iranian Journal of Health and Environment
2008-2029
Active
199
Iranian Journal of Medical Microbiology
1735-8612
Active
200
Iranian Journal of Medical Physics
1735-160X
Active
201
Iranian Journal of Nuclear Medicine
1681-2824
Active
202
Iranian Journal of Nursing and Midwifery Research [IJNMR]
1735-9066
Active
203
Iranian Journal of Nutrition Sciences and Food Technology
1735-7756
Active
204
Iranian Journal of Obstetric, Gynecology and Infertility [The]
1680-2993
Active
205
Iranian Journal of Ophthalmology
1735-4153
Active
206
Iranian Journal of Otorhinolaryngology
1560-1293
Active
207
Iranian Journal of Parasitology
1735-7020
Active
208
Iranian Journal of Pediatrics
2008-2142
Active
209
Iranian Journal of Psychiatry
1735-4587
Active
210
Iranian Journal of Psychiatry and Behavioral Sciences
1735-8639
Active
134
IMEMR Current Contents
EMR Journals List
S/N
ISSN
Status
211
Iranian Journal of Psychiatry and Clinical Psychology
(ANDEESHEH VA RAFTAR)
Journal Title
4315-1735
Active
212
Iranian Journal of Public Health
0304-4556
Active
213
Iranian Journal of Radiation Research
1728-4554
Active
214
Iranian Journal of Radiology
1735-1065
Active
215
Iranian Journal of Veterinary Research
1728-1997
Active
216
Iranian Rehabilitation Journal
1735-3602
Active
217
Iraqi Army Medical Journal
N/A
Interrupted
218
Iraqi Journal of Agriculture
1818-6645
Active
219
Iraqi Journal of Biotechnology
N/A
Interrupted
220
Iraqi Journal of Community Medicine
1684-5382
Interrupted
221
Iraqi Journal of Medical Sciences
1681-6579
Interrupted
222
Iraqi Journal of Microbiology
N/A
Interrupted
223
Iraqi Journal of Pharmaceutical Sciences
N/A
Interrupted
224
Iraqi Journal of Tropical Disease Researches
1814-0823
Interrupted
225
IRCMJ - Iranian Red Crescent Medical Journal
1561-4395
Active
226
Isra Medical Journal
2073-8285
Active
227
JABHS - Journal of the Arab Board of Health Specializations
1561-0217
Active
228
JAMC - Journal of Ayub Medical College - Abbotabad - Pakistan
1025-9589
Active
229
JBMS - Journal of the Bahrain Medical Society
1015-6321
Active
230
JBUMS - Journal of Babol University of Medical Sciences
1561-4107
Active
231
JCPSP - Journal of the College of Physicians and Surgeons
Pakistan
1022-386X
Active
232
JDT - Journal of Dentistry Tehran University of Medical Sciences
1735-2150
Active
233
JDUHS - Journal of the Dow University of Health Sciences
1995-2198
Active
234
JEMTAC - Journal of Emergency Medicine, Trauma and Acute
Care
1999-7086
Active
235
JESN - Journal of Egyptian Society of Nephrology [The]
N/A
Active
236
JISHIM - Journal of the International Society for the History of
Islamic Medicine
1303-667X
Active
237
JKCD - Journal of Khyber College of Dentistry
2220-2633
Active
238
JLDA - Journal of the Lebanese Dental Association
1810-9632
Active
239
JLUMHS - Journal of the Liaquat University of Medical Health
Sciences
1729-0341
Active
240
JMJ - Jamahiriya Medical Journal
N/A
Active
241
JMJ - Juba Medical Journal
N/A
Interrupted
242
JMR - Journal of Medical Research
1728-1962
Interrupted
243
JMS - Journal of Medical Sciences
1996-3262
Active
244
Joint Centre for Research in Prosthetics and Orthotics [The]
N/A
Interrupted
135
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
N/A
Interrupted
245
JOPDAK - Journal of the Pakistan Dental Association Karachi
246
Jordan Journal of Pharmaceutical Sciences
1995-7157
Active
247
Jordan Medical Journal
0446-9283
Active
248
Journal du Practicien
1113-5667
Interrupted
249
Journal of Arak University of Medical Sciences - Rahavard Danesh
1735-5338
Active
250
Journal of Basic and Applied Sciences
1814-8085
Active
251
Journal of Basic Medical Sciences
N/A
Interrupted
252
Journal of Childhood Studies
2090-0619
Active
253
Journal of Clinical Laboratory [The]
N/A
Active
254
Journal of Community Medicine
N/A
Interrupted
255
Journal of Dental Medicine - Tehran University of Medical Sciences
1024-641X
Active
256
Journal of Dental Research, Dental Clinics, Dental Prospects
2008-210X
Active
257
Journal of Dentistry - Shiraz University of Medical Sciences
1728-3426
Active
258
Journal of Dohuk University
1812-7568
Interrupted
259
Journal of Drug Research of Egypt
0085-2406
Active
260
Journal of Environmental Studies
1025-8620
Active
261
Journal of Faculty of Nursing and Midwifery Quarterly- Shaheed
Beheshti University of Medical Sciences
1605-8941
Active
262
Journal of Family and Community Medicine
1319-1683
Active
263
Journal of Fundamentals of Mental Health [The]
1028-6918
Active
264
Journal of Gorgan University of Medical Sciences
1562-4765
Active
265
Journal of Guilan University of Medical Sciences
2008-4048
Active
266
Journal of Health Administration
2008-1200
Active
267
Journal of Hepatology, Gastroenterology and Infectious Diseases
1110-0796
Interrupted
268
Journal of Hygiene and Health
1735-2363
Active
269
Journal of Infection and Public Health
1876-0341
Active
270
Journal of Injury and Violence Research
2008-2053
Active
271
Journal of Iranian Anatomical Sciences
1728-6158
Active
272
Journal of Isfahan Dental School
1735-255X
Active
273
Journal of Isfahan Medical School
1027-7595
Active
274
Journal of Islamic Dental Association of Iran [The] - JIDA
1024-6428
Active
275
Journal of Jahrom University of Medical Sciences
1735-5168
Active
276
Journal of Karbala University
1813-0410
Interrupted
277
Journal of Kerman University of Medical Sciences
1023-9510
Active
278
Journal of King Abdulaziz University - Medical Sciences
1319-1004
Interrupted
279
Journal of Legal Medicine and Forensic Sciences [The]
1110-6468
Active
136
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
280
Journal of Mashhad Dental School
1560-9286
Active
281
Journal of Mazandaran University of Medical Sciences
1735-9260
Active
282
Journal of Medical Council of Islamic Republic of Iran
1562-1073
Active
283
Journal of Medical Education
1735-3998
Active
284
Journal of Medical Science - Islamic Azad University of Mashhad
1735-7594
Active
285
Journal of Medical Sciences
1997-3438
Active
286
Journal of Medical Sciences
1682-4474
Active
287
Journal of Medicinal Plants
1684-0240
Active
288
Journal of Nephrology Urology and Transplantation
N/A
Interrupted
289
Journal of Ophthalmic and Vision Research
2008-2010
Active
290
Journal of Periodontology and Implant Dentistry
N/A
Active
291
Journal of Qazvin University of Medical Sciences [The]
1561-3666
Active
292
Journal of Rafsanjan University of Medical Sciences
1735-3165
Active
293
Journal of Rehabilitation
1607-2960
Active
294
Journal of Reproduction and Infertility
1726-7536
Active
295
Journal of Research in Behavioural Sciences
1735-2029
Active
296
Journal of Research in Health Sciences [JRHS]
1682-2765
Active
297
Journal of Research in Medical Sciences
1735-5311
Active
Journal of Sabzevar School of Medical Sciences
1606-7487
Active
1735-7586
Active
1562-272X
Active
298
299
300
Journal of School of Public Health and Institute of Public Health
Research
Journal of Shaheed Sadoughi University of Medical Sciences and
Health Services
301
Journal of Shahrekord University of Medical Sciences
1735-1448
Active
302
Journal of Surgery [The]
1681-4517
Interrupted
303
Journal of Taibah University Medical Sciences
1658-3612
Active
304
Journal of Tehran University Heart Center [The]
1735-8620
Active
305
Journal of the Arab Board of Medical Specializations
1561-0217
Active
306
Journal of the Arab Dentist
N/A
Interrupted
307
Journal of the Arab Neonatology Forum
1812-1756
Interrupted
308
Journal of the Arab Society for Medical Research
1687-4293
Active
309
Journal of the College of Dentistry - Baghdad
N/A
Interrupted
310
Journal of the Egyptian Medical Association [The]
0013-2411
Interrupted
311
Journal of the Egyptian National Cancer Institute
1110-0362
Active
N/A
Active
1110-1245
Active
312
Journal of the Egyptian Public Health Association [The]
313
Journal of the Egyptian Society of Endocrinology, Metabolism and
Diabetes [The]
137
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
314
Journal of the Egyptian Society of Obstetrics and Gynecology [The]
0258-3216
Interrupted
315
Journal of the Egyptian Society of Parasitology
1110-0583
Active
316
Journal of the Egyptian Society of Pharmacology and Experimental
Therapeutics [The]
N/A
Interrupted
317
Journal of the Egyptian Society of Toxicology
1110-127X
Active
318
Journal of the Faculty of Medicine - Baghdad
0041-9419
Active
319
Journal of the Medical Research Institute - Alexandria University
1110-0133
Interrupted
320
Journal of the Royal Medical Services
2078-8703
Active
321
Journal of the Saudi Heart Association
1016-7315
Active
322
Journal of Tropical Nephro-Urology
N/A
Active
2010-2525
Active
1735-076X
Active
1606-9366
Active
1560-9014
Active
N/A
Active
323
324
325
Journal of Veterinary Research
Journal of Zahedan University of Medical Sciences and Health
Services
Journal of Zanjan University of Medical Sciences and Health
Services
326
JPAD - Journal of Pakistan Association of Dermatologists
327
JPC - Journal of Pediatric Club [The]
328
JPDA - Journal of the Pakistan Dental Association
1680-2292
Active
329
JPIMS - Journal of Pakistan Institute of Medical Sciences
1683-6928
Interrupted
330
JPMA - Journal of Pakistan Medical Association
0030-9982
Active
331
JPMI - Journal of Postgraduate Medical Institute
1013-5472
Active
332
JPPS - Journal of Pakistan Psychiatric Society
1726-8710
Active
333
JRMS - Journal of Research in Medical Sciences
1735-1995
Active
334
JRRS - Journal of Research in Rehabilitation Sciences
1735-7519
Active
335
JSP - Journal of Surgery Pakistan International
1817-0242
Active
336
Jundishapur Journal of Microbiology [JJM]
2008-3645
Active
337
Kasr El Aini Journal of Surgery
0022-9237
Active
338
Khartoum Pharmacy Journal
N/A
Interrupted
339
Kidney Forum
1369-3050
Interrupted
340
KMJ - KUST Medical Journal
2072-7763
Active
341
KMJ - Kuwait Medical Journal
0023-5776
Active
342
KOOMESH - Journal of the Semnan University of Medical
Sciences
1608-7046
Active
343
Kufa Medical Journal
N/A
Interrupted
344
Lahore Journal of Public Health
N/A
Interrupted
345
Lebanese Science Journal
1561-3410
Active
346
Libyan Journal of Infectious Diseases [The]
347
LJM - Libyan Journal of Medicine
138
N/A
Active
1819-6357
Active
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
348
LMJ - Lebanese Medical Journal
0023-9852
Active
349
Maghreb Medical
0330-258X
Active
350
Mansoura Journal of Pharmaceutical Sciences
1110-1318
Active
351
Mansoura Medical Journal
1110-211X
Active
352
Maroc Medical
0025-4053
Active
353
MEAJO - Middle East African Journal of Ophthalmology
0974-9233
Active
354
Medical Arabization
N/A
Active
355
Medical Channel
1681-5491
Active
356
Medical Forum Monthly
1029-385X
Active
357
Medical Journal of Ahmed Maher Teaching Hospital [The]
N/A
Interrupted
358
Medical Journal of Basrah University [The]
0253-0759
Active
359
Medical Journal of Cairo University [The]
0045-3803
Active
360
Medical Journal of Islamic World Academy of Sciences
1016-3360
Active
361
Medical Journal of Mashad University of Medical Sciences
1735-4013
Active
362
Medical Journal of Tabriz University of Medical Sciences and
Health Services
1608-5671
Active
363
Medical Journal of Teaching Hospitals and Institutes [The]
1110-2039
Interrupted
364
Medical Journal of the Islamic Republic of Iran
1016-1430
Interrupted
365
Medical Journal of Tikrit University [The]
N/A
Interrupted
366
Medical Principles and Practice
1011-7571
Active
367
Medical Sciences Journal of Islamic Azad University
1023-5922
Active
368
Medical Spectrum [The]
0254-8534
Interrupted
369
Medicine Today
1813-9876
Active
370
MEJC - Middle East Journal of Cancer
2008-6709
Active
371
Middle East Journal of Anesthesiology
0544-0440
Active
372
Middle East Journal of Digestive Diseases
2008-5230
Active
373
Middle East Journal of Family Medicine
N/A
Active
374
Minoufia Medical Journal
1110-2098
Active
375
MJFCT - Mansoura Journal of Forensic Medicine and Clinical
Toxicology
1110-5437
Interrupted
376
Modares Journal of Medical Sciences
1562-9554
Active
377
Mother and Child
0379-2617
Interrupted
378
Neonatology
1687-0492
Interrupted
379
Neurosciences
1319-6138
Active
380
New Egyptian Journal of Medicine [The]
1110-1946
Active
381
New Iraqi Journal of Medicine [The]
1817-5562
Active
382
Nursing and Midwifery Research
1753-5001
Active
139
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
383
Ofogh-E-Danesh
1735-1855
Active
384
Oman Journal of Ophthalmology
0974-620X
Active
385
Oman Medical Journal
1999-768X
Active
386
Omdurman Journal of Pharmaceutical Sciences
N/A
Active
387
PAFMJ - Pakistan Armed Forces Medical Journal
0030-9648
Active
388
Pakistan Heart Journal
0048-2706
Active
389
Pakistan Journal of Biochemistry
0300-8185
Interrupted
390
Pakistan Journal of Chest Medicine
N/A
Active
391
Pakistan Journal of Clinical Psychology
1019-438X
Active
392
Pakistan Journal of Community Medicine [The]
N/A
Interrupted
393
Pakistan Journal of Health
N/A
Interrupted
394
Pakistan Journal of Medical and Health Sciences
1996-7195
Active
395
Pakistan Journal of Medical Ethics
N/A
Active
396
Pakistan Journal of Medical Sciences
1682-024X
Active
397
Pakistan Journal of Neurology
N/A
Interrupted
398
Pakistan Journal of Obstetrics and Gynaecology
N/A
Active
399
Pakistan Journal of Ophthalmology
0886-3067
Interrupted
400
Pakistan Journal of Orthodontics, Pediatric and Community
Dentistry
1608-134X
Interrupted
401
Pakistan Journal of Otolaryngology - Head and Neck Surgery
0257-4985
Active
402
Pakistan Journal of Pathology
1024-6193
Active
403
Pakistan Journal of Pharmaceutical Sciences
1011-601X
Active
404
Pakistan Journal of Pharmacology
0255-7088
Active
405
Pakistan Journal of Physiology
1819-270X
Active
406
Pakistan Journal of Psychology
0030-9869
Active
407
Pakistan Journal of Scientific and Industrial Research
0030-9885
Active
408
Pakistan Medical Journal
0031-000X
Interrupted
409
Pakistan Ophthalmology
0259-3661
Interrupted
410
Pakistan Oral and Dental Journal
1012-8700
Active
411
Pakistan Paediatric Journal
0304-4904
Active
412
Pan Arab Journal of Neurosurgery
1319-6995
Active
413
Pan Arab Journal of Orthopaedic and Trauma [The]
1607-4912
Active
414
Pan Arab Medical Journal
N/A
Interrupted
415
Payesh - Health Monitor
1680-7626
Active
416
Pejouhandeh: Bimonthly Research Journal
1735-1022
Active
417
PJC - Pakistan Journal of Cardiology
1016-1244
Active
140
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
418
PJMR - Pakistan Journal of Medical Research
0030-9842
Active
419
PJS - Pakistan Journal of Surgery
0258-8552
Active
420
PMJ - Palestinian Medical Journal
N/A
Active
421
Population Bulletin of ESCWA
0258-1914
Interrupted
422
Population Researches and Studies
N/A
Active
423
Population Sciences
424
Population Studies
N/A
Interrupted
1110-1342
Interrupted
425
Proceedings
N/A
Active
426
Professional Medical Journal - Quarterly [The]
1024-8919
Active
427
PUJ - Parasitologists United Journal
1687-7942
Active
428
Qatar Medical Journal
0253-8253
Active
429
Qom University of Medical Sciences Journal
1735-7799
Active
430
Quarterly Journal of Medical Ethics
2008-4374
Active
431
Quarterly Journal of Medical Law
432
Quarterly Journal of Relief and Rescue
433
Rehabilitation International
434
Research Centre Bulletin
435
Research Journal of Aleppo University - Medical Sciences Series
436
Revue Maghrebine de Pediatrie [La]
437
Revue Maghrebine d'Endocrinologie - Diabete et de Reproduction
[La]
438
Revue Marocaine de Chirurgie Orthopedique et Traumatologique
439
Revue Marocaine de Medecine et Sante
440
Revue Marocaine des Maladies de L'Enfant
441
Revue Tunisienne d'Infectiologie
442
Risafa Medical Journal
443
N/A
Active
4544-2008
Active
N/A
Interrupted
1019-5335
Interrupted
N/A
Active
0330-7611
Active
N/A
Active
N/A
Active
0251-0758
Active
N/A
Interrupted
1737-8958
Active
N/A
Interrupted
RMJ - Rawal Medical Journal
0303-5212
Active
444
Salmand - Iranian Journal of Aging
1735-806X
Active
445
Sana'a University Journal of Medical Sciences
N/A
Interrupted
446
Saudi Epidemiology Bulletin
1319-3965
Active
447
Saudi Heart Journal
1018-077X
Interrupted
448
Saudi Journal of Disability and Rehabilitation
1319-6499
Active
449
Saudi Journal of Gastroenterology [The]
1319-3767
Active
450
Saudi Journal of Oto-Rhino-Laryngology Head and Neck Surgery
[The]
1319-8491
Interrupted
451
Saudi Journal of Sports Medicine [The]
1319-6308
Interrupted
452
Saudi Medical Journal
0379-5284
Active
141
IMEMR Current Contents
EMR Journals List
S/N
ISSN
Status
453
Scientific and Research Journal of Army University of Medical
Sciences - J.A.U.M.S.
Journal Title
1727-1789
Active
454
Scientific Journal of Al-Azhar Medical Faculty [Girls] [The]
1110-2381
Interrupted
455
Scientific Journal of El-Minia Faculty of Medicine [The]
1110-2446
Active
456
Scientific Journal of Forensic Medicine
1027-1457
Active
457
Scientific Journal of Iranian Blood Transfusion Organization
Research Center [The]
1027-9520
Active
458
Scientific Journal of Kurdistan University of Medical Sciences
1560-652X
Active
459
Scientific Medical Journal
1110-5607
Active
460
Scientific Medical Journal - Biomomthly Medical Research Journal
Ahvaz Jundishapur University of Medical Sciences [The]
1026-8960
Active
461
Scientific Nursing Journal
1812-2388
Active
462
SDJ - Saudi Dental Journal [The]
1013-9052
Active
463
SGH Medical Journal
1658-2489
Active
464
SJA - Saudi Journal of Anaesthesia
1658-354X
Active
465
SJO - Saudi Journal of Ophthalmology
1319-4534
Active
466
SJPH - Sudanese Journal of Public Health
1990-7567
Active
467
Smile Dental Journal
2072-473X
Active
468
Social Welfare Quarterly
1735-8191
Active
469
South Valley Medical Journal
1110-7529
Active
470
SPJ - Saudi Pharmaceutical Journal
1319-0164
Active
471
SQUMJ - Sultan Qaboos University Medical Journal
2075-051X
Active
472
SST - Sante et Securite au Travail
N/A
Active
473
Strides in Development of Medical Education
1735-4242
Active
474
Sudan Journal of Medical Sciences
1858-5051
Active
475
Sudan Medical Journal
0491-4481
Interrupted
476
Sudan Medical Monitor
1858-5000
Active
477
Sudanese Journal of Dermatology
1815-3941
Active
478
Suez Canal University Medical Journal
1110-6999
Active
479
Tabib Attifil Alarabi
N/A
Interrupted
480
Tanaffos
1735-0344
Active
481
Tanta Medical Journal
1110-1415
Interrupted
482
Tanta Medical Sciences Journal
1687-5788
Active
483
Tehran University Medical Journal [TUMJ]
1683-1764
Active
484
Toloo-e-Behdasht
1728-5127
Active
485
Tunisie Medicale [La]
0041-4131
Active
486
University of Aden Journal of Natural and Applied Sciences
1606-8947
Active
142
IMEMR Current Contents
EMR Journals List
S/N
Journal Title
ISSN
Status
487
Urology Annals
0974-7796
Active
488
Urology Journal
1735-1308
Active
489
Veterinary Medical Journal
1110-1423
Active
490
Yafteh Journal
1563-0773
Active
491
Yemeni Journal for Medical Sciences [The]
N/A
Interrupted
492
YHMRJ - Yemeni Health and Medical Research Journal
N/A
Active
493
YJMHR-Yemeni Journal of Medical and Health Research
N/A
Interrupted
494
YMJ - Yemen Medical Journal
N/A
Interrupted
495
Zagazig Journal of Forensic Medicine and Toxicology
1687-160X
Active
496
Zagazig Journal of Pharmaceutical Sciences
1110-5089
Interrupted
497
Zagazig Medical Association Journal
1110-2322
Interrupted
498
Zagazig University Medical Journal
1110-1431
Interrupted
499
Zanco Journal of Medical Sciences
1995-5588
Active
Last update June 2011
143

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